Jaung Geng Lin

Summary

Affiliation: China Medical University
Country: Taiwan

Publications

  1. ncbi request reprint The effect of high and low frequency electroacupuncture in pain after lower abdominal surgery
    Jaung Geng Lin
    Acupuncture Research Center, China Medical College, Taichung, Taiwan, ROC
    Pain 99:509-14. 2002
  2. pmc The association between socioeconomic status and traditional chinese medicine use among children in Taiwan
    Chun chuan Shih
    1The School of Chinese Medicine for Post Baccalaureate, I Shou University, Kaohsiung County 82445, Taiwan
    BMC Health Serv Res 12:27. 2012
  3. ncbi request reprint The role of acupuncture in cancer supportive care
    Jaung Geng Lin
    School of Chinese Medicine, China Medical University, 91 Hsueh Shih Road, Taichung, Taiwan
    Am J Chin Med 40:219-29. 2012
  4. pmc Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats
    Rong Tsung Lin
    Department of Internal Medicine, Division of Endocrinology and Metabolism, Tungs Taichung Metro Harbor Hospital, Taichung County, Taiwan, Republic of China
    BMC Complement Altern Med 9:26. 2009
  5. ncbi request reprint Acupuncture analgesia: a review of its mechanisms of actions
    Jaung Geng Lin
    Graduate Institute of Chinese Medical Science, China Medical University, Taiwan
    Am J Chin Med 36:635-45. 2008
  6. doi request reprint The mechanistic studies of acupuncture and moxibustion in Taiwan
    Jaung Geng Lin
    Graduate Institute of Chinese Medical Science, China Medical University Taichung, Taichung, Taiwan, China
    Chin J Integr Med 17:177-86. 2011
  7. ncbi request reprint Review: acupuncture analgesia in clinical trials
    Jaung Geng Lin
    Graduate Institute of Acupuncture Science, China Medical University, Taiwan
    Am J Chin Med 37:1-18. 2009
  8. doi request reprint Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and Ras
    Chyi Lo
    School of Chinese Medicine, China Medical University, Taichung, Taiwan
    Melanoma Res 21:267-73. 2011
  9. ncbi request reprint Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3
    Chin Cheng Su
    School of Chinese Medicine, Department of Microbiology, China Medical University, No 91, Hsueh Shih Road, Taichung City 404, Taiwan, ROC
    Anticancer Res 26:4379-89. 2006
  10. ncbi request reprint Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9
    Ya Yin Chen
    School of Chinese Medicine, China Medical University, Taichung 404, Taiwan, R O C
    Int J Oncol 36:1113-20. 2010

Collaborators

Detail Information

Publications93

  1. ncbi request reprint The effect of high and low frequency electroacupuncture in pain after lower abdominal surgery
    Jaung Geng Lin
    Acupuncture Research Center, China Medical College, Taichung, Taiwan, ROC
    Pain 99:509-14. 2002
    ..Our findings demonstrates that preoperative treatment with low-EA and high-EA can reduce postoperative analgesic requirements and associated side effects in patients undergoing lower abdominal surgery...
  2. pmc The association between socioeconomic status and traditional chinese medicine use among children in Taiwan
    Chun chuan Shih
    1The School of Chinese Medicine for Post Baccalaureate, I Shou University, Kaohsiung County 82445, Taiwan
    BMC Health Serv Res 12:27. 2012
    ..Limited studies are available on the socioeconomic status (SES) associated with TCM use among the pediatric population. We report on the association between SES and TCM use among children and adolescents in Taiwan...
  3. ncbi request reprint The role of acupuncture in cancer supportive care
    Jaung Geng Lin
    School of Chinese Medicine, China Medical University, 91 Hsueh Shih Road, Taichung, Taiwan
    Am J Chin Med 40:219-29. 2012
    ..Head and neck cancer patients receiving radiotherapy may develop xerostomia, which may be relieved by acupuncture. Acupuncture may also cause sedative and hypnotic effects in cancer patients for treating nervousness and insomnia...
  4. pmc Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats
    Rong Tsung Lin
    Department of Internal Medicine, Division of Endocrinology and Metabolism, Tungs Taichung Metro Harbor Hospital, Taichung County, Taiwan, Republic of China
    BMC Complement Altern Med 9:26. 2009
    ..This study reports the use of a large dose of prednisolone to evaluate the effects of EA in a state of insulin resistance...
  5. ncbi request reprint Acupuncture analgesia: a review of its mechanisms of actions
    Jaung Geng Lin
    Graduate Institute of Chinese Medical Science, China Medical University, Taiwan
    Am J Chin Med 36:635-45. 2008
    ..However, results of these experiments are still controversial. After 30 years of acupuncture research, there are still many puzzles left to be solved regarding the mechanism of AA...
  6. doi request reprint The mechanistic studies of acupuncture and moxibustion in Taiwan
    Jaung Geng Lin
    Graduate Institute of Chinese Medical Science, China Medical University Taichung, Taichung, Taiwan, China
    Chin J Integr Med 17:177-86. 2011
    ..Mild local heat stress upregulated hepatic gene expression of heat shock protein 70 and protected the liver from subsequent ischemia-reperfusion injury. These studies supplement the knowledge of the mechanism of acupuncture...
  7. ncbi request reprint Review: acupuncture analgesia in clinical trials
    Jaung Geng Lin
    Graduate Institute of Acupuncture Science, China Medical University, Taiwan
    Am J Chin Med 37:1-18. 2009
    ..Therefore, the real effect of acupuncture can be investigated well. We conclude that acupuncture is a proven treatment for relieving pain. This conclusion is based on specific effects of acupuncture rather than placebo...
  8. doi request reprint Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and Ras
    Chyi Lo
    School of Chinese Medicine, China Medical University, Taichung, Taiwan
    Melanoma Res 21:267-73. 2011
    ..S2 human melanoma cells. These data, therefore, provide evidence for the role of GA as a potential cancer chemotherapeutic agent, which can markedly inhibit the invasive capacity of melanoma cells...
  9. ncbi request reprint Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3
    Chin Cheng Su
    School of Chinese Medicine, Department of Microbiology, China Medical University, No 91, Hsueh Shih Road, Taichung City 404, Taiwan, ROC
    Anticancer Res 26:4379-89. 2006
    ..Curcumin also promoted the expression of Bax, cytochrome C, p53 and p21 but inhibited the expression of Bcl-2. These observations suggest that curcumin may have a possible therapeutic potential in colon cancer patients...
  10. ncbi request reprint Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9
    Ya Yin Chen
    School of Chinese Medicine, China Medical University, Taichung 404, Taiwan, R O C
    Int J Oncol 36:1113-20. 2010
    ..In conclusion, these findings suggest that molecular targeting of MMP-9 mRNA expression by emodin, aloe-emodin and rhein might be a useful strategy for chemo-prevention and/or chemo-therapeutics of tongue cancers...
  11. ncbi request reprint Gallic acid induces apoptosis in A375.S2 human melanoma cells through caspase-dependent and -independent pathways
    Chyi Lo
    School of Chinese Medicine, China Medical University, Taichung 404, Taiwan, ROC
    Int J Oncol 37:377-85. 2010
    ..Therefore, GA may also induce apoptosis through a caspase-independent pathway. Our results suggest that GA might be a potential anticancer compound; however, in depth in vivo studies are needed to elucidate the exact mechanism...
  12. doi request reprint Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model
    Yi Shih Ma
    Graduate Institute of Chinese Medicine, China Medical University, Taichung 404, Taiwan
    Food Chem Toxicol 50:1271-8. 2012
    ..Overall, the potent in vitro and in vivo antitumor activities of emodin suggest that it might be developed for treatment of colon cancer in the future...
  13. ncbi request reprint Blocking the DNA repair system by traditional Chinese medicine?
    Mao Feng Sun
    Laboratory of Computational and Systems Biology, School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
    J Biomol Struct Dyn 28:895-906. 2011
    ..These features strengthen the binding affinity between Ku86 and the potential TCM ligand. We reported all four TCM compounds are potential Ku86 inhibitors and may be used to enhance radiotherapy for cancer treatment...
  14. ncbi request reprint Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells
    Hong Jye Hong
    School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    Cardiovasc Res 61:159-68. 2004
    ..However, whether ROS are involved in Ang II-induced ET-1 gene expression and the related intracellular mechanisms in vascular SMCs remains to be determined...
  15. ncbi request reprint Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells
    Yung Tsuan Ho
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung 404, Taiwan
    Anticancer Res 29:4063-70. 2009
    ....
  16. doi request reprint Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways
    Ching Lung Liao
    Graduate Institute of Chinese Medicine, China Medical University, Taichung 404, Taiwan, ROC
    Food Chem Toxicol 50:1734-40. 2012
    ....
  17. pmc Electroacupuncture-induced cholinergic nerve activation enhances the hypoglycemic effect of exogenous insulin in a rat model of streptozotocin-induced diabetes
    Yu Chen Lee
    Department of Acupuncture, China Medical University Hospital, Taichung, Taiwan
    Exp Diabetes Res 2011:947138. 2011
    ..This phenomenon may be related to enhancement of insulin signaling rather than to changes in FFA concentration...
  18. ncbi request reprint Microglia, apoptosis and interleukin-1beta expression in the effect of sophora japonica l. on cerebral infarct induced by ischemia-reperfusion in rats
    Chih Jui Lao
    Graduate Institute of Chinese Medical Science, College of Chinese Medicine, Taichung, Taiwan
    Am J Chin Med 33:425-38. 2005
    ..This effect of SJ involves its suppressive action of microglia, interleukin-1beta and apoptosis...
  19. doi request reprint An extract of Agaricus blazei Murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo
    Jaung Geng Lin
    China Medical University, Taichung, Taiwan
    Integr Cancer Ther 11:29-36. 2012
    ..Isolated T cells from spleens of ABM-treated mice resulted in increased T-cell proliferation compared with the untreated control with concanavalin A stimulation...
  20. ncbi request reprint Gastrodia elata BL mediates the suppression of nNOS and microglia activation to protect against neuronal damage in kainic acid-treated rats
    Ching Liang Hsieh
    Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan
    Am J Chin Med 33:599-611. 2005
    ..5 g/kg and 1.0 g/kg of GE did not. This study demonstrated that GE was able to reduce nNOS, microglia activation and apoptosis, suggesting that GE has a protective effect against neuronal damage in KA-treated rats...
  21. doi request reprint The pulse spectrum analysis at three stages of pregnancy
    Yin Tzu Liao
    School of Chinese Medicine, China Medical University, Taichung, Taiwan
    J Altern Complement Med 18:382-6. 2012
    ....
  22. ncbi request reprint Effects of electroacupuncture at 'Anmian (Extra)' acupoints on sleep activities in rats: the implication of the caud al nucleus tractus solitarius
    Pei Lu Yi
    Neuroscience Laboratory, Department of Neurology, China Medical University Hospital, Taichung, Taiwan, ROC
    J Biomed Sci 11:579-90. 2004
    ..These results suggest that the caudal NTS may be involved in the regulation of EAc-induced sleep alterations...
  23. ncbi request reprint Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions
    Chin Cheng Su
    School of Chinese Medicine, China Medical University, Taichung City 404, Taiwan, ROC
    Anticancer Res 26:1281-8. 2006
    ..Curcumin was also found to significantly repress the in vitro invasion of colo 205 cells...
  24. ncbi request reprint Ultrasound induces cyclooxygenase-2 expression through integrin, integrin-linked kinase, Akt, NF-kappaB and p300 pathway in human chondrocytes
    Horng Chaung Hsu
    Department of Orthopaedics, China Medical University Hospital, Taichung, Taiwan
    Cell Signal 19:2317-28. 2007
    ..Taken together, our results provide evidence that US stimulation increases COX-2 expression in chondrocytes via the integrin/ILK/Akt/NF-kappaB and p300 signaling pathway...
  25. ncbi request reprint Alendronate inhibits cell invasion and MMP-2 secretion in human chondrosarcoma cell line
    Te Jen Lai
    Institute of Medicine, Chung Shan Medical University, Department of Psychiatry, Chung Shan Medical University Hospital, Taiwan, China
    Acta Pharmacol Sin 28:1231-5. 2007
    ..The aim of the present study was to investigate the effect of alendronate, a bisphosphonate, on the invasion and migration of human chondrosarcoma cells (JJ012)...
  26. doi request reprint Increase in plasma glucose lowering action of rosiglitazone by electroacupuncture at bilateral Zusanli acupoints (ST.36) in rats
    Hui Ching Pai
    Graduate Institute of Integrated Medicine, China Medical University, Taichung City, Taiwan
    J Acupunct Meridian Stud 2:147-51. 2009
    ..We applied EA at the Zusanli (ST.36) acupuncture point (acupoint) in combination with rosiglitazone (TZD) administration to evaluate their effect on plasma glucose and to explore possible mechanisms of action...
  27. pmc Paeoniae alba Radix Promotes Peripheral Nerve Regeneration
    Kun Shan Huang
    Graduate Institute of Chinese Medical Science, China Medical University, Taiwan
    Evid Based Complement Alternat Med 2011:109809. 2011
    ..05). These results suggest that the PR extract can be a potential nerve growth-promoting factor, being salutary in aiding the growth of injured peripheral nerve...
  28. ncbi request reprint Comments on "Line patterns in the mosaic electric properties of human skin--a cross-correlation study"
    Yue Der Lin
    School of Post Baccalaureate Chinese Medicine, China Medical College, Taichung, Taiwan
    IEEE Trans Biomed Eng 49:274. 2002
  29. ncbi request reprint Chinese medicinal herbs Muh-Shiang Bin-Lang-Wan increases the motility of sphincter of Oddi in anesthetized rabbits through activation of M1 muscarinic receptors
    Yung ing Kuo
    Institute of Chinese Medicine Science, China Medical University, Taichung, Taiwan, ROC
    Life Sci 74:533-42. 2003
    ..We conclude that MSBLW is effective in increasing the SO motility in rabbits through activation of M1 muscarinic receptors. However, potential application of MSBLW in the treatment of human biliary disorders needs further evaluation...
  30. ncbi request reprint The study of electroacupuncture on cerebral blood flow in rats with and without cerebral ischemia
    Ching Liang Hsieh
    Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan
    Am J Chin Med 34:351-61. 2006
    ..We concluded that both 2 and 15 Hz EA at both Zusanli acupoints induced the increase of CBF in rats with and without CI. Whether the effect of EA is related to NO or CGRP will be investigated in a future study...
  31. ncbi request reprint Activation of activator protein-1 in cells exposed to electrical stimulation of various parameters used in electroacupuncture therapy
    Sheng Feng Hsu
    Acupuncture Department, China Medical University Hospital, School of Chinese Medicine, China Medical University Taichung, Taiwan, ROC
    Am J Chin Med 31:967-75. 2003
    ..In conclusion, our data suggest that electrical stimulation with an appropriate frequency, duration and pulse width could cause an increase in AP-1 activity in cells...
  32. ncbi request reprint Chrysophanol-induced cell death (necrosis) in human lung cancer A549 cells is mediated through increasing reactive oxygen species and decreasing the level of mitochondrial membrane potential
    Chien Hang Ni
    Department of Chinese Medicine, E Da Hospital I Shou University, Kaohsiung 824, Taiwan Graduate Institute of Chinese Medicine, China Medical University, Taichung 404, Taiwan
    Environ Toxicol . 2012
    ..In conclusion, human lung cancer A549 cells treated with chrysophanol exhibited a cellular pattern associated with necrotic cell death and not apoptosis in vitro. © 2012 Wiley Periodicals, Inc. Environ Toxicol 2012...
  33. ncbi request reprint Earthworm extracts facilitate PC12 cell differentiation and promote axonal sprouting in peripheral nerve injury
    Chao Tsung Chen
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 38:547-60. 2010
    ..25 microg/ml was significantly more than those in the controls (p < 0.05). These results showed that EW extracts can be a potential growth-promoting factor on regenerating peripheral nerves...
  34. ncbi request reprint Effects of Agaricus blazei Murill extract on immune responses in normal BALB/c mice
    Nou Ying Tang
    School of Chinese Medicine, Taichung, Taiwan, PCR
    In Vivo 23:761-6. 2009
    ..Taken together, these results show that ABM extract promoted immunomodulations in normal BALB/c mice in vitro and in vivo...
  35. ncbi request reprint Panax Notoginseng Burk attenuates impairment of learning and memory functions and increases ED1, BDNF and beta-secretase immunoreactive cells in chronic stage ischemia-reperfusion injured rats
    Chin Min Chuang
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 36:685-93. 2008
    ..The effect that PN has on astrocytes, NF-kappaB and beta-secreatase immunoreactive cells requires further study...
  36. ncbi request reprint Effect of electroacupuncture and transcutaneous electrical nerve stimulation at Hegu (LI.4) acupuncture point on the cutaneous reflex
    Qwang Yuen Chang
    Institute of Chinese Medical Science, China Medical College 91 Hseuh Shin Road, Taichung, Taiwan, ROC
    Acupunct Electrother Res 27:191-202. 2002
    ..In addition, the electrical stimulation of higher frequency such as 100Hz TENS acting on CR caused habituation easier...
  37. ncbi request reprint Effect of Polygala tenuifolia root on behavioral disorders by lesioning nucleus basalis magnocellularis in rat
    Yung Li Chen
    Graduate Institute of Chinese Medical Science, China Medical University, 91 HSue Hsi Rd, Taichung City, Taiwan
    J Ethnopharmacol 95:47-55. 2004
    ..The results suggest that PTW extract has some repairing effects on the memory and behavioral disorders produced by lesioning of the NBM in rats...
  38. ncbi request reprint Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells
    You Cheng Hseu
    Department of Food Science, Chungtai Institute of Health Sciences and Technology, Taichung, Taiwan
    Nutr Cancer 48:189-97. 2004
    ..The data suggest that A. camphorata exerts antiproliferative action and growth inhibition on HL-60 cells through apoptosis induction and that it may have anticancer properties valuable for application in drug products...
  39. doi request reprint Action potential bursts in central snail neurons elicited by paeonol: roles of ionic currents
    Yi Hung Chen
    Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung, Taiwan, China
    Acta Pharmacol Sin 31:1553-63. 2010
    ..to investigate the effects of 2'-hydroxy-4'-methoxyacetophenone (paeonol) on the electrophysiological behavior of a central neuron (right parietal 4; RP4) of the giant African snail (Achatina fulica Ferussac)...
  40. ncbi request reprint Effect of low-power pulsed laser on peripheral nerve regeneration in rats
    Yueh Sheng Chen
    Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Microsurgery 25:83-9. 2005
    ..These results suggest that pulsed laser irradiation could elicit suppressing effects on regenerating nerves...
  41. ncbi request reprint Observation of sympathomimetic effect of ear acupuncture stimulation for body weight reduction
    Ein Yiao Shen
    Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 37:1023-30. 2009
    ..Accordingly, the combination of an optimal exercise and diet program with repeated acupoint therapy may be necessary to maintain a healthy body weight...
  42. ncbi request reprint Variations of brain activities of acupuncture to TE5 of left hand in normal subjects
    Sheng Feng Hsu
    Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 39:673-86. 2011
    ..Acupuncture is proven to be able to affect brain waves, as the stimulation might have changed the tissues between the cranium and scalp; therefore, the brain waves are detected more easily...
  43. doi request reprint Safe needling depth of acupuncture points
    Pei Chi Chou
    School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan
    J Altern Complement Med 17:199-206. 2011
    ..The objective of this review is to investigate the existing scientific information on the safe needling depth of acupuncture points...
  44. ncbi request reprint Effects of "Chinese yam" on hepato-nephrotoxicity of acetaminophen in rats
    Shih Chang Lee
    Institute of Food Science, National Chung Hsing University, Taichung 40227, Taiwan, China
    Acta Pharmacol Sin 23:503-8. 2002
    ..To study the effect of yam in Taiwan, which is a commonly used Chinese medicine, on hepato-nephro-toxicity in rats...
  45. ncbi request reprint Antiproliferative effect of isosteviol on angiotensin-II-treated rat aortic smooth muscle cells
    Kar Lok Wong
    Department of Anesthesia, China Medical University and Hospital, Taichung, Taiwan, ROC
    Pharmacology 76:163-9. 2006
    ..Thus, this study provides important insights that may contribute to the effects of isosteviol on the cardiovascular system...
  46. ncbi request reprint Reducing fatigue of athletes following oral administration of huangqi jianzhong tang
    Kung tung Chen
    Department of General Education, Ming Hsin Institute of Technology Hsinchu, Taiwan, China
    Acta Pharmacol Sin 23:757-61. 2002
    ..To study the effect of Huangqi Jianzhong Tang in reducing fatigue improvement in athletes...
  47. doi request reprint Low back pain associated with sociodemographic factors, lifestyle and osteoporosis: a population-based study
    Yi Chun Chou
    Department of Physical Medicine and Rehabilitation, China Medical University Hospital, Taichung, Taiwan
    J Rehabil Med 45:76-80. 2013
    ..To investigate the prevalence and factors associated with low back pain among adults in Taiwan...
  48. pmc Electroacupuncture reduces cocaine-induced seizures and mortality in mice
    Yi Hung Chen
    Graduate Institute of Acupuncture Science, China Medical University, Taichung 40402, Taiwan
    Evid Based Complement Alternat Med 2013:134610. 2013
    ..These results suggest that EA alleviates cocaine-induced seizures and mortality and that the dopamine D3 receptor is involved, at least in part, in the anticonvulsant effects of EA in mice...
  49. doi request reprint Tanshinone IIA Attenuates H₂O₂ -induced injury in human umbilical vein endothelial cells
    Paul Chan
    Division of Cardiovascular Medicine, Department of Internal Medicine, Taipei Medical University, Taipei, Taiwan, R O C
    Am J Chin Med 40:1307-19. 2012
    ....
  50. doi request reprint Diallyl sulfide inhibits murine WEHI-3 leukemia cells in BALB/c mice in vitro and in vivo
    Fu Shun Yu
    School of Dental Hygiene, China Medical University, Taichung, Taiwan, Republic of China
    Hum Exp Toxicol 28:785-90. 2009
    ..One of the major characteristic of WEHI-3 leukemia is the enlarged spleen in murine after intraperitoneal (i.p.) injection of WEHI-3 cells. In conclusion, DAS affects WEHI-3 cells both in vitro and in vivo...
  51. doi request reprint Health-related quality of life in the elderly practicing T'ai Chi Chuan
    Tsung Jung Ho
    Chinese Medical Science, China Medical University, Taichung, Taiwan
    J Altern Complement Med 13:1077-83. 2007
    ..In Taiwan, TCC is a form of exercise that is widely practiced by the elderly. The aim of this cross-sectional study was to investigate the effects of TCC on the health-related quality of life (HRQOL) in the senior population...
  52. ncbi request reprint How to standardize 3 finger positions of examiner for palpating radial pulses at wrist in traditional Chinese medicine
    Chu Chang Tyan
    Graduate Institute of Chinese Medical Science, China Medical University CMU, Dept of Chinese Medicine, China Medical University Hospital CMUH, Taichung, Taiwan
    Acupunct Electrother Res 32:87-96. 2007
    ..Therefore, it is reasonable to assume that the length of the Cun is equal to the length of the DWP. Our findings confirm that the location of Cun is from the distal wrist crease to the highest point of PB...
  53. ncbi request reprint Effects of acupuncture on post-cesarean section pain
    Hung Chien Wu
    College of Dental Medicine, Kaohsiung Medical University, Taiwan, China
    Chin Med J (Engl) 122:1743-8. 2009
    ..Post-operation pain is a very subjective phenomenon. The aim of this study was to find out the effects of acupuncture or electro-acupuncture on post-cesarean pain...
  54. ncbi request reprint Capsaicin-induced apoptosis in human hepatoma HepG2 cells
    Shang Pang Huang
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Anticancer Res 29:165-74. 2009
    ....
  55. ncbi request reprint Eriobotrya japonica leaf and its triterpenes inhibited lipopolysaccharide-induced cytokines and inducible enzyme production via the nuclear factor-kappaB signaling pathway in lung epithelial cells
    Chang Hsien Lee
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung 40402, Taiwan
    Am J Chin Med 36:1185-98. 2008
    ..In conclusion, our findings suggested the potential mechanisms of PPY and its active component, ursolic acid, in the treatment of pulmonary inflammation...
  56. ncbi request reprint The utilization of traditional Chinese medicine and associated factors in Taiwan in 2002
    Chun chuan Shih
    Graduate Institute of Chinese Medical Science, College of Chinese Medicine, China Medical University, Taichung, Taiwan, China
    Chin Med J (Engl) 122:1544-8. 2009
    ..This study analyzes the utilization rate and the factors associated with the utilization of TCM in Taiwan...
  57. ncbi request reprint Pulse spectrum analysis, a faster and easier way to predict outcome of sepsis?
    Chien Jung Lin
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 36:1061-70. 2008
    ..The pulse spectrum analysis may be applied to evaluate the prognosis of CLP rats, and the rapidly and highly elevated C2 harmonic had a strong association with the 3-day mortality of CLP rats...
  58. doi request reprint Differences in pulse spectrum analysis between atopic dermatitis and nonatopic healthy children
    Jyh Min Liou
    Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan
    J Altern Complement Med 17:325-8. 2011
    ..The purpose of this study is to determine the differences in pulse spectrum analysis between patients with AD and nonatopic healthy individuals...
  59. ncbi request reprint Enhanced insulin sensitivity using electroacupuncture on bilateral Zusanli acupoints (ST 36) in rats
    Shih Liang Chang
    Graduate Institute of Integration of Chinese and Western Medicine, China Medical University, Taichung City, Taiwan, ROC
    Life Sci 79:967-71. 2006
    ..Thus, EA should be considered as an alternative method for improving insulin sensitivity and/or increase insulin-hypoglycemic activity in rats...
  60. pmc Effect of Qigong on quality of life: a cross-sectional population-based comparison study in Taiwan
    Tsung Jung Ho
    School of Public Health, China Medical University, Taichung, Taiwan
    BMC Public Health 11:546. 2011
    ..In Taiwan, Waitankung, a type of Qigong, is as popular as Tai Chi Chuan. This population-based comparison study compares the health-related quality of life between people practicing Waitankung and their comparable community residents...
  61. pmc Utilization pattern of traditional Chinese medicine for liver cancer patients in Taiwan
    Yueh Hsiang Liao
    Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan
    BMC Complement Altern Med 12:146. 2012
    ..Liver cancer is the second most common cancer in Taiwan. This study aimed to analyze the TCM utilization patterns of patients with liver cancer from 1996-2007 using a population-based random sample of one million insured patients...
  62. ncbi request reprint Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells
    Ya Yin Chen
    China Medical University, No 91, Hsueh Shih Road, Taichung 404, Taiwan
    Anticancer Res 30:945-51. 2010
    ..In conclusion, these agents induced DNA damage followed by the inhibition of DNA repair-associated gene expressions, including ATM, ATR, 14-3-3sigma, BRCA1, DNA-PK and MGMT in SCC-4 human tongue cancer cells...
  63. ncbi request reprint Effect of salvia miltiorrhiza bunge on cerebral infarct in ischemia-reperfusion injured rats
    Chih Jui Lo
    Institute of Chinese Medical Science, China Medical College, Taichung, Taiwan, ROC
    Am J Chin Med 31:191-200. 2003
    ..The therapeutic effect of SM may be partly due to its free radical scavenging activities...
  64. ncbi request reprint A clinical study of acupuncture and SSP (silver spike point) electro-therapy for dry eye syndrome
    Kuo Lieh Tseng
    Graduate Institute of Integration Chinese and Western Medicine, China Medical University, Taichung, Taiwan
    Am J Chin Med 34:197-206. 2006
    ..The SSP electro-therapy not only alleviated dry eye syndrome, but also reduced the number of applications of artificial tears necessary...
  65. ncbi request reprint Screening from the world's largest TCM database against H1N1 virus
    Tung Ti Chang
    Laboratory of Computational and Systems Biology, School of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan
    J Biomol Struct Dyn 28:773-86. 2011
    ..We therefore suggest that an enhanced hemagglutinin inhibitor, based on our scaffold, should be designed to bind both Glu83 and Asp103 with high affinity...
  66. ncbi request reprint Involvement of serotonin in the hypoglycemic response to 2 Hz electroacupuncture of zusanli acupoint (ST36) in rats
    Shih Liang Chang
    Graduate Institute of Integration Chinese and Western Medicine, China Medical University, Taichung, Taiwan, ROC
    Neurosci Lett 379:69-73. 2005
    ..Furthermore, injection of serotonin decreased the plasma glucose levels significantly. Therefore, we suggest that serotonin also involved in the hypoglycemic action of 2 Hz EA at both zusanli acupoints of normal rats...
  67. ncbi request reprint Effects of electroacupuncture treatment on impaired cognition and quality of life in Taiwanese stroke patients
    PeiChi Chou
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    J Altern Complement Med 15:1067-1073. 2009
    ..The objective of this study was to investigate the effect of electroacupuncture on cognitive function and health-related quality of life in patients who have had a stroke...
  68. ncbi request reprint Proliferative effects of Chishao on Schwann cells are FGF-uPA, and ERK- and JNK-dependent
    Kun Shan Huang
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 37:1191-202. 2009
    ..Based on the results, applying appropriate doses of chishao to Schwann cells would be a potential approach for enhancing neuron regeneration...
  69. ncbi request reprint Localization of cholecystokinin and vasoactive intestinal peptide in lower biliary tract in cats following electroacupuncture on right Qimen (LR14) and Riyue (GB 24): an immunohistochemistry study
    Yung Ling Kuo
    Institute of Chinese Medicine Science, China Medical College, Taichung, Taiwan, Republic of China
    Acupunct Electrother Res 30:15-25. 2005
    ..We conclude that EA regulates the biliary motility though increasing the distribution of CCK- and VIP-containing cells in duodenum and the sphincter of Oddi...
  70. pmc The stimulation effect of auricular magnetic press pellets on older female adults with sleep disturbance undergoing polysomnographic evaluation
    Chyi Lo
    School of Nursing, China Medical University, Taichung 40402, Taiwan Department of Nursing, China Medical University Hospital, Taichung, Taiwan
    Evid Based Complement Alternat Med 2013:530438. 2013
    ..Conclusions. Auricular therapy using magnetic pellets and stimulation by pressing was more effective in improving the sleep quality compared to auricular therapy without any stimulation...
  71. pmc How to design the control group in randomized controlled trials of acupuncture?
    Jaung Geng Lin
    School of Chinese Medicine, China Medical University, No 91 Hsueh Shih Road, Taichung 40402, Taiwan
    Evid Based Complement Alternat Med 2012:875284. 2012
    ..We compared the advantages and limitations associated with different control group designs in acupuncture RCTs, to assist researchers in this field...
  72. doi request reprint Microarray analysis reveals the inhibition of nuclear factor-kappa B signaling by aristolochic acid in normal human kidney (HK-2) cells
    Ya Yin Chen
    China Medical University, Taichung, Taiwan, China
    Acta Pharmacol Sin 31:227-36. 2010
    ..To study the molecular mechanism underlying the effect of aristolochic acid (AA), a major active component of plants from the Aristolochiaceae family using microarray analysis...
  73. ncbi request reprint 17beta-estradiol downregulates angiotensin-II-induced endothelin-1 gene expression in rat aortic smooth muscle cells
    Hong Jye Hong
    School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    J Biomed Sci 11:27-36. 2004
    ..Thus, this study provides important new insight regarding the molecular pathways that may contribute to the proposed beneficial effects of estrogen on the cardiovascular system...
  74. doi request reprint Osteoblast-derived TGF-beta1 stimulates IL-8 release through AP-1 and NF-kappaB in human cancer cells
    Yi Chin Fong
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    J Bone Miner Res 23:961-70. 2008
    ..The aim of this study was to investigate whether osteoblast-derived TGF-beta1 is associated with osteolytic bone diseases...
  75. ncbi request reprint Acupuncture stimulation at Baihui acupoint reduced cerebral infarct and increased dopamine levels in chronic cerebral hypoperfusion and ischemia-reperfusion injured sprague-dawley rats
    Chin Min Chuang
    Graduate Institute of Chinese Medical Science, College of Chinese Medicine, China Medical University, Taichung, Taiwan
    Am J Chin Med 35:779-91. 2007
    ..The AS also reduced brain atrophy after cerebral infarct, suggesting that AS at the Baihui acupoint acts as neuroprotector. However, regular stimulation at the Baihui acupoint enhances cognition and memory functions need further study...
  76. pmc Patterns of medical pluralism among adults: results from the 2001 National Health Interview Survey in Taiwan
    Chun chuan Shih
    China Medical University, Taichung, Taiwan
    BMC Health Serv Res 10:191. 2010
    ..A population-based survey and linkage with medical records was conducted to investigate MP amongst the Taiwanese population. Previous research suggests an increasing use of CAM worldwide...
  77. doi request reprint Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9
    Yung Tsuan Ho
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung 404, Taiwan
    Cancer Lett 279:155-62. 2009
    ....
  78. pmc Acupuncture for the treatment of opiate addiction
    Jaung Geng Lin
    School of Chinese Medicine, China Medical University, No 91 Hsueh Shih Road, Taichung 40402, Taiwan
    Evid Based Complement Alternat Med 2012:739045. 2012
    ....
  79. ncbi request reprint Effects of Ding-Chuan-Tang on bronchoconstriction and airway leucocyte infiltration in sensitized guinea pigs
    Shung Te Kao
    Department of Immunology and Cellular Physiology, Institute of Chinese Medicine Science, China Medical University, Taiwan, ROC
    Immunopharmacol Immunotoxicol 26:113-24. 2004
    ....
  80. ncbi request reprint [Current situation of the university education and examination system of Traditional Chinese Medicine (TCM) in Taiwan]
    Pei Chi Chou
    The Institute of Traditional Chinese Medicine TCM, The University of Chinese Medical Sciences, Taichung, Taiwan, 404, China
    Zhonghua Yi Shi Za Zhi 39:270-2. 2009
    ..In 1998, Chang Gung University established the department of TCM. With the development of TCM education, the licensing examination of Traditional Chinese physicians was gradually standardized...
  81. ncbi request reprint Carryover effects alter FMRI statistical analysis in an acupuncture study
    Tsung Jung Ho
    Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
    Am J Chin Med 36:55-70. 2008
    ..Therefore, in fMRI experiments with strong carryover effects, a single-block experimental design with multiple repetitions, separated by long enough periods of time, should be more suitable to extract task BOLD effects...
  82. ncbi request reprint [Development of traditional Chinese medicine in Taiwan before 1960s]
    Guang Wei Chen
    Graduate Institute of Chinese Medical Science, Taichung, China
    Zhonghua Yi Shi Za Zhi 37:71-5. 2007
    ..In this article, we will introduce the early development of traditional Chinese medicine in Taiwan chronologically...
  83. ncbi request reprint Immediate effects of acupuncture on gait patterns in patients with knee osteoarthritis
    Tung Wu Lu
    Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan, China
    Chin Med J (Engl) 123:165-72. 2010
    ..The study aimed to investigate the immediate effects of acupuncture on gait patterns in patients with knee OA...
  84. ncbi request reprint [Development of the public health insurance system of Traditional Chinese Medicine in Taiwan and the current situation]
    Pei Chi Chou
    School of Chinese Medicine, Chinese Medical University, Taichung, 404, Taiwan
    Zhonghua Yi Shi Za Zhi 40:222-4. 2010
    ..It is a valuable reference for other countries...
  85. ncbi request reprint The study of dynamic response to acute hemorrhage by pulse spectrum analysis
    Yu Hsin Chang
    Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan, R O C
    Am J Chin Med 34:449-60. 2006
    ..The observed change could be attributed to the induction of functional qi, and is a result of qi-blood balancing activity that organisms hold to survive against acute bleeding...
  86. ncbi request reprint Different patterns of pulse spectrum between survivors and non-survivors during progressive hemorrhage in rats
    Yu Hsin Chang
    Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan, ROC
    Am J Chin Med 34:575-89. 2006
    ..These results suggest that C3 might play an important role in physiology regarding surviving capability after progressive hemorrhage...
  87. ncbi request reprint Multiple sources of endogenous opioid peptide involved in the hypoglycemic response to 15 Hz electroacupuncture at the Zhongwan acupoint in rats
    Jaung Geng Lin
    Taipei Chinese Medical Association, Taipei City, Taiwan, ROC
    Neurosci Lett 366:39-42. 2004
    ..Increase in beta-endorphin levels from the adrenal gland enhances the secretion of insulin, there by reducing plasma glucose levels, and is partially involved in this EA stimulation...
  88. ncbi request reprint Release of beta-endorphin from adrenal gland to lower plasma glucose by the electroacupuncture at Zhongwan acupoint in rats
    Jaung Geng Lin
    Institute of Chinese Medical Science, China Medical College, Taichung City, Taiwan
    Neurosci Lett 326:17-20. 2002
    ..In conclusion, the increase of plasma beta-endorphin by EA at 2 Hz is mainly from the adrenal gland...
  89. ncbi request reprint The central serotonergic system mediates the analgesic effect of electroacupuncture on ZUSANLI (ST36) acupoints
    Fang Chia Chang
    Neuroscience Laboratory, Department of Neurology, China Medical University Hospital, Taichung, Taiwan ROC
    J Biomed Sci 11:179-85. 2004
    ..These observations suggest that 5-HT(1A) and 5-HT(3) receptors partially mediate the analgesic effects of EAc, but that the 5-HT(2) receptor is conversely involved in the nociceptive response...
  90. ncbi request reprint Needling sensation: explanation of incongruent conclusion drawn from acupuncture FMRI study
    Tsung Jung Ho
    J Altern Complement Med 13:13-4. 2007
  91. ncbi request reprint The efficacy of acupressure for decreasing agitated behaviour in dementia: a pilot study
    Man Hua Yang
    School of Nursing, National Yang Ming University, Taipei, Taiwan, Republic of China
    J Clin Nurs 16:308-15. 2007
    ..To investigate the efficacy of acupressure in decreasing agitated behaviours associated with dementia...
  92. ncbi request reprint The effects of acupuncture on cardiac muscle cells and blood pressure in spontaneous hypertensive rats
    Hung Chien Wu
    Department of Acupuncture, China Medical University Hospital, Taichung402, Taiwan, ROC
    Acupunct Electrother Res 29:83-95. 2004
    ..Therefore, acupuncture could be a good treatment modality for hypertension and hypertrophy of the heart...
  93. ncbi request reprint Preconditioned somatothermal stimulation on median nerve territory increases myocardial heat shock protein 70 and protects rat hearts against ischemia-reperfusion injury
    Jen Hwey Chiu
    Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan
    J Thorac Cardiovasc Surg 125:678-85. 2003
    ....