Da Tian Bau

Summary

Affiliation: China Medical University Hospital
Country: Taiwan

Publications

  1. Pei J, Chang W, Hsu P, Chen C, Cheng S, Wang Y, et al. The contribution of XRCC3 genotypes to childhood acute lymphoblastic leukemia. Cancer Manag Res. 2018;10:5677-5684 pubmed publisher
    ..The polymorphism may be a potential detector and predictor of childhood ALL. ..
  2. Huang C, Chang W, Tsai C, Hsia T, Shen T, Bau D, et al. Interleukin-18 promoter genotype is associated with the risk of nasopharyngeal carcinoma in Taiwan. Cancer Manag Res. 2018;10:5199-5207 pubmed publisher
  3. Hsu P, Pei J, Chen C, Chang W, Kuo C, Cheng S, et al. Association of Matrix Metallopeptidase-2 Promoter Polymorphisms With the Risk of Childhood Leukemia. Anticancer Res. 2019;39:1185-1190 pubmed publisher
    ..The MMP-2 promoter genotypes play a minor role in determining personal susceptibility to childhood leukemia among the Taiwanese. ..
  4. Wu M, Wang Y, Li H, Chen W, Liao C, Shih T, et al. The Contribution of Interleukin-12 Genetic Variations to Taiwanese Lung Cancer. Anticancer Res. 2018;38:6321-6327 pubmed publisher
    ..0043). IL-12A rs568404 AA genotype may contribute to the etiology and serve as a genomic determinant of lung cancer in Taiwanese, especially smokers. ..
  5. Yen C, Tsai C, Chang W, Yang Y, Hung Y, Lee H, et al. Novel Combination of Arsenic Trioxide (As2O3) Plus Resveratrol in Inducing Programmed Cell Death of Human Neuroblastoma SK-N-SH Cells. Cancer Genomics Proteomics. 2018;15:453-460 pubmed publisher
    ..Combined treatment at extremely low concentration of two agents from natural products, As2O3 and resveratrol, has high potential as a cocktail of anticancer drugs for neuroblastoma. ..
  6. Yueh T, Hung Y, Shih T, Wu C, Wang S, Lai Y, et al. Contribution of Murine Double Minute 2 Genotypes to Colorectal Cancer Risk in Taiwan. Cancer Genomics Proteomics. 2018;15:405-411 pubmed publisher
    ..The combined effects of MDM2 SNP309 and other genes (such as matrix metalloproteinases) on CRC susceptibility and prognosis, should also be taken into consideration in the era of precision medicine. ..
  7. Hsiao W, Tsai C, Chang W, Wang S, Chao C, Chen W, et al. Association of Polymorphisms in DNA Repair Gene XRCC3 with Asthma in Taiwan. In Vivo. 2018;32:1039-1043 pubmed publisher
    ..No interaction of these genotypes with gender or age were found. Although XRCC3 plays a role in asthma etiology, the variant XRCC3 genotypes do not serve as practicable predictive markers for asthma risk in Taiwanese. ..
  8. Liao C, Wu H, Hu P, Hsu S, Shen T, Hsia T, et al. The Association of Matrix Metalloproteinase-1 Promoter Polymorphisms with Prostate Cancer in Taiwanese Patients. Anticancer Res. 2018;38:3907-3911 pubmed publisher
    ..6910), compared to those carrying the wild-type 2G allele. Our findings suggest that the polymorphic genotypes at MMP-1 promoter -1607 may play a major role in determining personal cancer susceptibility for prostate cancer in Taiwan. ..
  9. Lu M, Yang M, Li P, Fang H, Huang H, Chan Y, et al. Effect of Oligomeric Proanthocyanidin on the Antioxidant Status and Lung Function of Patients with Chronic Obstructive Pulmonary Disease. In Vivo. 2018;32:753-758 pubmed publisher
    ..Lung function was not significantly different between the two groups after 8 weeks. OPC supplementation was effective in increasing the antioxidant capacity, in addition to improving the lipid profiles in patients with COPD. ..

More Information

Publications59

  1. request reprint
    Shih L, Li C, Sun K, Chen L, Hsu C, Hung Y, et al. Association of Matrix Metalloproteinase-7 Genotypes to the Risk of Oral Cancer in Taiwan. Anticancer Res. 2018;38:2087-2092 pubmed
    ..Our results indicate that the MMP7 promoter genotypes only play an indirect role in determining the personal susceptibility to oral cancer in Taiwan. ..
  2. Hu P, Chang W, Chou A, Hsia N, Hung Y, Lin C, et al. The Association of MMP-8 Genotypes with Pterygium. In Vivo. 2018;32:41-46 pubmed
    ..Polymorphisms at MMP-8 -799C/T, Val436Ala and Lys460Thr may not mainly contribute to determining personal susceptibility to pterygium in the Taiwanese examined. ..
  3. Pei J, Chang W, Hsu P, Hung Y, Cheng S, Tsai C, et al. The Contribution of MMP-8 Promoter Genotypes to Childhood Leukemia. In Vivo. 2017;31:1059-1064 pubmed
    ..Our findings suggest that the polymorphisms at MMP-8 -799C/T, Val436Ala and Lys460Thr may not play a major role in determining the personal susceptibility to childhood ALL in Taiwan. ..
  4. request reprint
    Chuang C, Wang C, Hsu C, Hsiao C, Chen G, Yen S, et al. Contribution of Double-strand Break Repair Gene Nijmegen Breakage Syndrome 1 Genotypes, Gender Difference and Smoking Status to Taiwanese Lung Cancer. Anticancer Res. 2017;37:2417-2423 pubmed
    ..64) but not among the females and non-smokers. The CC genotype of NBS1 Glu185Gln may increase lung cancer risk only for males and smokers and may serve as a practical marker for early detective and predictive purposes of lung cancer. ..
  5. request reprint
    Tsai C, Chang W, Lin K, Shih L, Tsai M, Hsiao C, et al. Significant association of Interleukin-10 genotypes and oral cancer susceptibility in Taiwan. Anticancer Res. 2014;34:3731-7 pubmed
    ..The AG and GG genotypes of IL10 A-1082G, together with smoking and areca chewing habits, synergistically contribute to individual susceptibility for oral cancer. ..
  6. Tsai C, Hsu H, Wang Y, Chang W, Shih L, Sun K, et al. Contribution of MMP2 Promoter Genotypes to Oral Cancer Susceptibility, Recurrence and Metastasis in Taiwan. Anticancer Res. 2018;38:6821-6826 pubmed publisher
    ..The CT and TT genotypes of MMP2 promoter 1306 may have a protective effect on oral cancer susceptibility and metastasis risk within 5 years for Taiwanese. They may serve as predictive markers for oral cancer in precise medical practice. ..
  7. Liu L, Lin Y, Lin Y, Ho C, Hung C, Way T, et al. Banana Flower Extract Suppresses Benign Prostatic Hyperplasia by Regulating the Inflammatory Response and Inducing G1 Cell-cycle Arrest. In Vivo. 2018;32:1373-1379 pubmed publisher
    ..In summary, banana flower extract may be used as a therapeutic agent for BPH via anti-proliferative and anti-inflammatory activities. ..
  8. Yueh T, Wu C, Hung Y, Chang W, Fu C, Pei J, et al. The Contribution of MMP-7 Genotypes to Colorectal Cancer Susceptibility in Taiwan. Cancer Genomics Proteomics. 2018;15:207-212 pubmed
    ..The further genotyping work on MMP-7 and other genes (such as other MMPs, oncogenes and tumor suppression genes) on CRC susceptibility and prognosis, should be taken into consideration spontaneously in the precision medicine era. ..
  9. Lu M, Yang M, Li P, Fang H, Huang H, Chan Y, et al. Effects of Nutritional Intervention on the Survival of Patients with Cardiopulmonary Failure Undergoing Extracorporeal Membrane Oxygenation Therapy. In Vivo. 2018;32:829-834 pubmed publisher
    ..Following individual nutrition goals is critical for better outcomes, and this analysis might be useful in establishing individualized nutrition goals for oriental population when caring for critically ill patients. ..
  10. request reprint
    Shen T, Chang W, Tsai C, Chao C, Lin Y, Hsiao C, et al. The Contribution of Matrix Metalloproteinase-1 Promoter Genotypes in Taiwan Lung Cancer Risk. Anticancer Res. 2018;38:253-257 pubmed
    ..The MMP1 -1607 1G allele is a non-significant protective biomarker for lung cancer in Taiwan. ..
  11. request reprint
    Sun K, Tsai C, Chang W, Shih L, Chen L, Tsai M, et al. The Contribution of Matrix Metalloproteinase-1 Genotype to Oral Cancer Susceptibility in Taiwan. In Vivo. 2016;30:439-44 pubmed
    ..The 1G/2G genotype of MMP1 promoter 1607 may have a protective effect on oral cancer risk for smokers. The detailed mechanisms involved in this require further investigation. ..
  12. request reprint
    Chang W, Lin E, Hsu S, Hu P, Chuang C, Liao C, et al. Baicalin Scavenged Reactive Oxygen Species and Protected Human Keratinocytes Against UVB-induced Cytotoxicity. In Vivo. 2016;30:605-10 pubmed
  13. request reprint
    Shen T, Hsia T, Chao C, Chen W, Chen C, Chen W, et al. The Contribution of MMP-8 Promoter Polymorphisms in Lung Cancer. Anticancer Res. 2017;37:3563-3567 pubmed
    ..The polymorphisms MMP-8 C-799T, Val436Ala and Lys460Thr may not play a major role in mediating personal susceptibility to lung cancer in Taiwan. ..
  14. Liao C, Chang W, Hu P, Wu H, Hsu S, Liu Y, et al. The Contribution of MMP-7 Promoter Polymorphisms in Renal Cell Carcinoma. In Vivo. 2017;31:631-635 pubmed
    ..The MMP-7 C-153T polymorphism was not identified among the subjects investigated. Our findings suggest that the two MMP-7 polymorphisms A-181G and C-153T do not play a major role in determining personal susceptibility to RCC in Taiwan. ..
  15. Lai Y, Gong C, Fu C, Yueh T, Tsai C, Chang W, et al. The Contribution of Matrix Metalloproteinase-1 Genotypes to Hepatocellular Carcinoma Susceptibility in Taiwan. Cancer Genomics Proteomics. 2017;14:119-125 pubmed
    ..The 1G allele of MMP1 promoter 1607 may have a protective effect on HCC risk for non-smokers in Taiwan and further validations are needed in other population groups. ..
  16. Liao C, Chang W, Tsai C, Hu P, Wu H, Hsu S, et al. Association of Matrix Metalloproteinase-7 Genotypes with the Risk of Bladder Cancer. In Vivo. 2018;32:1045-1050 pubmed publisher
    ..The results of this study suggest that the two MMP-7 polymorphisms, - A-181G and C-153T, do not play a major role in determining personal susceptibility to bladder cancer in Taiwan. ..
  17. Chen G, Shen T, Chang W, Tsai C, Li H, Chuang C, et al. The Contribution of MMP-7 Promoter Polymorphisms to Taiwan Lung Cancer Susceptibility. Anticancer Res. 2018;38:5671-5677 pubmed publisher
    ..There was no evidence that the genotypes of MMP-7 A-181G may act as a biomarker in determining personal susceptibility to lung cancer in Taiwan. ..
  18. Tsai T, Wang Y, Chang W, Tsai C, Wu H, Hsu H, et al. Association of Matrix Metalloproteinase-8 Genotypes with the Risk of Bladder Cancer. Anticancer Res. 2018;38:5159-5164 pubmed publisher
    ..The polymorphism Lys460Thr at MMP8 was not found among Taiwanese patients. MMP8 C-799T, Val436Ala and Lys460Thr may only play an indirect role in determining personal cancer susceptibility for bladder cancer in Taiwan. ..
  19. request reprint
    Chen L, Huang C, Tsou Y, Bau D, Tsai M. Prognostic factor of severe complications in patients with hypopharyngeal cancer with primary concurrent chemoradiotherapy. Anticancer Res. 2015;35:1735-41 pubmed
    ..In advanced stage, but still resectable hypopharyngeal tumors, the poorer quality of life due to non-function larynx was noted after treating with CCRT. ..
  20. request reprint
    Hsia T, Chang W, Liang S, Chen W, Tu C, Chen H, et al. Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk in Taiwan males and smokers. Anticancer Res. 2014;34:7039-44 pubmed
    ..0003 and 0.0004, respectively). The CC and TC genotypes of IL-10 T-819C compared to the TT genotype may have a protective effect on lung cancer risk in Taiwan, particularly among males and smokers. ..
  21. request reprint
    Chang W, Tsai C, Wang J, Ying T, Hsiao T, Chuang C, et al. Contribution of X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) Genotype to Leiomyoma Risk. Anticancer Res. 2015;35:4691-6 pubmed
    ..The T allele (CT and TT genotypes) of XRCC3 rs861539 contributes to increased risk of leiomyoma among Taiwanese women and may serve as a early detection and predictive marker. ..
  22. request reprint
    Hsiao C, Liu L, Shih T, Chuang C, Chen G, Wang H, et al. The Association of Matrix Metalloproteinase-8 Promoter Genotypes in Breast Cancer. Anticancer Res. 2018;38:2181-2185 pubmed
    ..MMP8 -799C/T, Val436Ala and Lys460Thr polymorphisms may only play an indirect role in determining personal cancer susceptibility to breast cancer in Taiwan. ..
  23. request reprint
    Hsia T, Chang W, Chen W, Liang S, Tu C, Chen H, et al. Genotype of DNA double-strand break repair gene XRCC7 is associated with lung cancer risk in Taiwan males and smokers. Anticancer Res. 2014;34:7001-5 pubmed
    ..2×10(-4) and 3.1×10(-4), respectively). The GG and GT genotypes of XRCC7 rs7003908 compared to the TT genotype had a protective effect on lung cancer risk in Taiwan, particularly among males and smokers. ..
  24. Hsiao C, Liu L, Shih T, Lai Y, Hsu S, Wang H, et al. The Association of Matrix Metalloproteinase-1 Promoter Polymorphisms with Breast Cancer. In Vivo. 2018;32:487-491 pubmed
    ..Other early diagnostic and predictive markers are urgently needed for personalized and precise breast cancer detection and therapy. ..
  25. request reprint
    Lin K, Yang M, Tsai C, Chang W, Hsiao C, Jeng L, et al. The Role of MTHFR Genotype in Colorectal Cancer Susceptibility in Taiwan. Anticancer Res. 2018;38:2001-2006 pubmed
    ..MTHFR rs1801133 T allele serves as a predictive marker for CRC risk and future studies with larger samples and functional evaluation are warranted to validate the current findings. ..
  26. request reprint
    Chang W, Liao C, Tsai C, Hu P, Wu H, Hsu S, et al. Association of Enhancer of Zeste 2 (EZH2) Genotypes with Bladder Cancer Risk in Taiwan. Anticancer Res. 2016;36:4509-14 pubmed
    ..Our findings provide evidence that the T allele of EZH2 rs887569 may be associated with the lower risk of bladder cancer development, especially among non-smokers. ..
  27. request reprint
    Su C, Lane H, Hsiao C, Liu L, Ji H, Li H, et al. Matrix Metalloproteinase-1 Genetic Polymorphism in Breast Cancer in Taiwanese. Anticancer Res. 2016;36:3341-5 pubmed
    ..The genotype of MMP1 promoter 1607 may not be a major determining factor for breast cancer risk. The contribution of MMP1 promoter 1607 genotype to prognosis and subtypes of breast cancer needs further investigation. ..
  28. Chang W, Liu L, Hsiao C, Su C, Wang H, Ji H, et al. The contributions of the tissue inhibitor of metalloproteinase-1 genotypes to triple negative breast cancer risk. Biomedicine (Taipei). 2016;6:4 pubmed publisher
    ..Thus, it is our conclusion that the CC genotype of TIMP-1 rs4898 compared to the TT wild-type genotype may increase the risk for breast cancer, especially TNBC in Taiwan, and may serve as an early detective and predictive marker. ..
  29. request reprint
    Lai C, Chang W, Hsieh Y, Hsu C, Tsai C, Chen A, et al. Association of Tissue Inhibitor of Metalloproteinase-1 Genotypes with Lung Cancer Risk in Taiwan. Anticancer Res. 2016;36:155-60 pubmed
    ..The CC genotype of TIMP1 rs4898 compared to the TT wild-type genotype may increase lung cancer risk in Taiwan and may serve as a marker for early detective and predictive purposes. ..
  30. request reprint
    Su C, Chang W, Hu P, Hsiao C, Ji H, Liao C, et al. Contribution of DNA Double-strand Break Repair Gene XRCC3 Genotypes to Triple-negative Breast Cancer Risk. Cancer Genomics Proteomics. 2015;12:359-67 pubmed
    ..46-4.28; p=4.63*10(-4)). XRCC3 rs861539 TT is a potential predictive marker for TNBC in Taiwanese women and investigations in other populations are warranted for further universal application in cancer detection and prediction. ..
  31. request reprint
    Yang M, Hsu C, Chang W, Yueh T, Lai Y, Chuang C, et al. Tumor Necrosis Factor-α Genotypes Are Associated with Hepatocellular Carcinoma Risk in Taiwanese Males, Smokers and Alcohol Drinkers. Anticancer Res. 2015;35:5417-23 pubmed
    ..0003, 0.0003, 0.0014, 0.6127, 0.7442 and 0.3010, respectively). Our results suggest that the AA and AG polymorphism of TNFA -308G/A genotypes associated with HCC risk in Taiwan, particularly among males, smokers and alcohol drinkers. ..
  32. request reprint
    Chang W, Wang S, Chuang C, Ji H, Hsiao C, Hsu C, et al. Contribution of Interleukin-4 Genotypes to Lung Cancer Risk in Taiwan. Anticancer Res. 2015;35:6297-301 pubmed
    ..The TT genotype of IL-4 C-589T compared to the CC wild-type genotype may have a protective effect on lung cancer risk in Taiwan and may serve as an early detection and prediction marker. ..
  33. request reprint
    Pei J, Hsu P, Chou A, Tsai C, Chang W, Hsiao C, et al. Matrix Metalloproteinase-1 Genotype Contributes to the Risk of Non-solid Tumor in Childhood Leukemia. Anticancer Res. 2016;36:5127-5132 pubmed
    ..0183 and 0.0004, respectively) for childhood ALL, but there was no such difference for those having an age at onset of 3.5 years or more. Our results indicate that the MMP1 rs1799750 1G allele is a protective biomarker for childhood ALL. ..
  34. request reprint
    Hsia T, Chang W, Wang S, Shen T, Hsiao W, Liu C, et al. The Contribution of Interleukin-10 Promoter Genotypes to Susceptibility to Asthma in Adults. In Vivo. 2015;29:695-9 pubmed
    ..The CC genotype of IL10 T-819C compared to the TT genotype may have a protective effect on asthma risk in younger adults (25-40 years old), and males in Taiwan. ..
  35. request reprint
    Chang W, Yueh T, Tsai C, Ji H, Wu C, Wang S, et al. Contribution of DNA Repair Xeroderma Pigmentosum Group D Genotypes to Colorectal Cancer Risk in Taiwan. Anticancer Res. 2016;36:1657-63 pubmed
    ..3531), location (p=0.3006) and lymph node metastasis (p=0.1061). Asp312Asn, Lys751Gln and promoter -114 of the XPD gene were not found to be adequate predictive markers for colorectal cancer risk in Taiwan. ..
  36. request reprint
    Lo W, Chang W, Hsu H, Ji H, Hsiao C, Tsai C, et al. Significant Association of Interleukin-10 Polymorphisms with Childhood Leukemia Susceptibility in Taiwan. In Vivo. 2016;30:265-9 pubmed
    ..16-12.72, respectively). There was no difference in the distribution of A-1082G genotypes between childhood ALL and control groups. The genotypes at IL10 T-819C and A-592C may serve as predictive biomarkers for childhood ALL in Taiwan. ..
  37. request reprint
    Chang W, Liao C, Tsai C, Hu P, Wu H, Hsu S, et al. The Role of IL-10 Promoter Polymorphisms in Renal Cell Carcinoma. Anticancer Res. 2016;36:2205-9 pubmed
    ..The CC genotype of IL-10 T-819C genotype may have a protective effect on RCC risk in Taiwan. Further investigation with larger sample size in addition to genotype-phenotype correlation and intracellular mechanisms are our future work. ..
  38. request reprint
    Pei J, Chang W, Hsu P, Tsai C, Hsu C, Ji H, et al. The Association of Flap Endonuclease 1 Genotypes with the Risk of Childhood Leukemia. Cancer Genomics Proteomics. 2016;13:69-74 pubmed
    ..53 and 0.32, 95%CI=0.31-0.90 and 0.15-0.70, p=0.0042). The FEN1 rs174538 A allele is a protective biomarker for childhood ALL and this association is more significant in males and in patients at onset age of 3.5 years or older. ..
  39. request reprint
    Tsai C, Chang W, Gong C, Shih L, Chen L, Lin E, et al. Contribution of Matrix Metallopeptidase-1 Genotypes, Smoking, Alcohol Drinking and Areca Chewing to Nasopharyngeal Carcinoma Susceptibility. Anticancer Res. 2016;36:3335-40 pubmed
    ..The 1G/1G genotype of MMP-1 promoter -1607 may independently have a protective effect on NPC risk, without interaction with behavioral factors, including cigarette, alcohol and areca consumption. ..
  40. request reprint
    Chang W, Liao C, Miao C, Wu H, Hou L, Hsiao C, et al. The role of functional polymorphisms of cyclooxygenase 2 in renal cell carcinoma. Anticancer Res. 2014;34:5481-6 pubmed
    ..0331). These evidence indicated that COX2 G-765C genotype involved in the etiology of RCC and may serve as a novel genetic marker for susceptibility of RCC. ..
  41. Shen T, Tsai C, Chang W, Wang S, Chao C, Hsiao C, et al. Association of Interleukin-12A rs568408 with Susceptibility to Asthma in Taiwan. Sci Rep. 2017;7:3199 pubmed publisher
    ..0085) among asthmatic patients. These results suggest that IL-12A rs568408 may contribute to the etiology and symptoms severity of asthma, indicating its usefulness as a predictive and diagnostic biomarker of asthma. ..
  42. request reprint
    Chou A, Hsiao C, Shih T, Wang H, Tsai C, Chang W, et al. The Contribution of Matrix Metalloproteinase-7 Promoter Genotypes in Breast Cancer in Taiwan. Anticancer Res. 2017;37:4973-4977 pubmed
  43. Hung Y, Tsai C, Wu C, Shih L, Chen Y, Liu Y, et al. The Contribution of Matrix Metalloproteinase-8 Promoter Polymorphism to Oral Cancer Susceptibility. In Vivo. 2017;31:585-590 pubmed
    ..Our findings suggest that the polymorphisms at MMP-8 C-799T or Val436Ala may not play a major role in mediating personal risk of oral cancer; however, the detailed mechanisms require further investigation. ..
  44. request reprint
    Bau D, Yang M, Tsou Y, Lin S, Wu C, Hsieh H, et al. Colorectal cancer and genetic polymorphism of DNA double-strand break repair gene XRCC4 in Taiwan. Anticancer Res. 2010;30:2727-30 pubmed
    ..We conclude that the G allele of XRCC4 G-1394T may contribute to colorectal carcinogenesis and may be useful for early detection of colorectal cancer. ..
  45. Bau D, Tsai C, Lin C, Tsai R, Tsai M. Association of alpha B-crystallin genotypes with oral cancer susceptibility, survival, and recurrence in Taiwan. PLoS ONE. 2011;6:e16374 pubmed publisher
    ..05). Our results provide the first evidence that the G allele of CRYAB C-802G is correlated with oral cancer risk and this polymorphism may be a useful marker for oral cancer recurrence and survival prediction for clinical reference. ..
  46. request reprint
    Pei J, Chou A, Hsu P, Tsai C, Chang W, Wu M, et al. Contribution of Matrix Metalloproteinase-7 Genotypes to the Risk of Non-solid Tumor, Childhood Leukemia. Anticancer Res. 2017;37:6679-6684 pubmed
    ..5 years or more. Our results indicate that the MMP7 A-181G genotype interacts with age and gender and may serve as an early and predictive biomarker for childhood ALL. ..
  47. Chou A, Shen M, Chen F, Hsiao C, Shih L, Chang W, et al. The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis. Cancer Genomics Proteomics. 2017;14:455-460 pubmed
    ..12, 95%CI=0.03-0.53, p=0.0050). The FEN1 rs174538 A allele is a novel protective biomarker for endometriosis and this genotype may have interactions with age- and hormone-related factors on the development of endometriosis. ..
  48. request reprint
    Chang W, Tsai C, Ji H, Wu H, Chang Y, Lien C, et al. Associations of cyclooxygenase 2 polymorphic genotypes with bladder cancer risk in Taiwan. Anticancer Res. 2013;33:5401-5 pubmed
    ..Our findings provide evidence that the C allele of Cox-2 promoter G-765C may be associated with the overexpression of COX-2 during bladder cancer development and may be a useful marker for the early detection of bladder cancer. ..
  49. request reprint
    Yueh T, Chou A, Gong C, Fu C, Pei J, Wu M, et al. The Contribution of Excision Repair Cross-complementing Group 1 Genotypes to Colorectal Cancer Susceptibility in Taiwan. Anticancer Res. 2017;37:2307-2313 pubmed
    ..ERCC1 rs11615 T allele serves as a predictive marker for CRC risk and future studies with larger samples and functional evaluation are warranted to validate these findings. ..
  50. request reprint
    Hsia T, Tsai C, Liang S, Chang W, Lin L, Chen W, et al. Effects of ataxia telangiectasia mutated (ATM) genotypes and smoking habits on lung cancer risk in Taiwan. Anticancer Res. 2013;33:4067-71 pubmed
    ..0045 and 0.2758, respectively). Our results provide evidence that the A allele of ATM rs652311 may be associated with lung cancer risk, and may enhance the effects of smoking habit on lung cancer development. ..