Chien Lin Chen

Summary

Country: Taiwan

Publications

  1. pmc Impact of sleep dysfunction on anorectal motility in healthy humans
    Tso Tsai Liu
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    J Neurogastroenterol Motil 17:180-4. 2011
  2. pmc Atypical symptoms in patients with gastroesophageal reflux disease
    Chih Hsun Yi
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    J Neurogastroenterol Motil 18:278-83. 2012
  3. doi request reprint Influence of intraluminal acidification on esophageal secondary peristalsis in humans
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, 707, Sec 3, Chung Yang Rd, Hualien 970, Taiwan
    Dig Dis Sci 58:1948-54. 2013
  4. doi request reprint Association between swallow perception and esophageal bolus clearance in patients with globus sensation
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, 707, Sec 3, Chung Yang Rd, Hualien, Taiwan
    Dig Dis Sci 58:1042-8. 2013
  5. doi request reprint Esophageal solid bolus transit: studies using combined multichannel intraluminal impedance and manometry in healthy volunteers
    C L Chen
    Department of Medicine Radiology, Buddhist Tzu Chi General Hospital and Tzu Chi University, 707 Section 3 Chung Yang Road, Hualien, Taiwan
    Dis Esophagus 26:91-6. 2013
  6. doi request reprint Heterogeneity in oesophageal dysfunction among patients with different reflux symptoms
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Eur J Gastroenterol Hepatol 24:1059-65. 2012
  7. ncbi request reprint Identification of impaired oesophageal bolus transit and clearance by secondary peristalsis in patients with non-obstructive dysphagia
    C L Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 20:980-8. 2008
  8. doi request reprint Utility of esophageal impedance in identifying dysmotility in patients with erosive esophagitis
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    Dis Esophagus 21:539-43. 2008
  9. doi request reprint Proximal versus distal oesophageal motility as assessed by combined impedance and manometry
    C L Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, Australia
    Dig Liver Dis 41:104-9. 2009
  10. doi request reprint Clinical correlates of dysphagia to oesophageal dysmotility: studies using combined manometry and impedance
    C L Chen
    Department of Medicine, Buddhist Tzu Chi Medical Center and University School of Medicine, Hualien, Taiwan
    Neurogastroenterol Motil 20:611-7. 2008

Collaborators

Detail Information

Publications65

  1. pmc Impact of sleep dysfunction on anorectal motility in healthy humans
    Tso Tsai Liu
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    J Neurogastroenterol Motil 17:180-4. 2011
    ..We aimed to investigate whether sleep dysfunction would influence anorectal motility as determined by anorectal manometry. The effect of anxiety on anorectal motility was also determined...
  2. pmc Atypical symptoms in patients with gastroesophageal reflux disease
    Chih Hsun Yi
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    J Neurogastroenterol Motil 18:278-83. 2012
    ..We aimed to compare atypical characteristics in patients with NERD and ERD. We also investigated the presence of histological esophagitis in patients with NERD and ERD...
  3. doi request reprint Influence of intraluminal acidification on esophageal secondary peristalsis in humans
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, 707, Sec 3, Chung Yang Rd, Hualien 970, Taiwan
    Dig Dis Sci 58:1948-54. 2013
    ..Secondary peristalsis contributes to clearance of retained refluxate or material from the esophagus...
  4. doi request reprint Association between swallow perception and esophageal bolus clearance in patients with globus sensation
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, 707, Sec 3, Chung Yang Rd, Hualien, Taiwan
    Dig Dis Sci 58:1042-8. 2013
    ..Globus sensation is common, but its pathogenesis is not yet clear...
  5. doi request reprint Esophageal solid bolus transit: studies using combined multichannel intraluminal impedance and manometry in healthy volunteers
    C L Chen
    Department of Medicine Radiology, Buddhist Tzu Chi General Hospital and Tzu Chi University, 707 Section 3 Chung Yang Road, Hualien, Taiwan
    Dis Esophagus 26:91-6. 2013
    ..Solid boluses can be regarded as a valuable complement to viscous boluses in the detection of esophageal motility abnormalities when applied with combined MII-EM...
  6. doi request reprint Heterogeneity in oesophageal dysfunction among patients with different reflux symptoms
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Eur J Gastroenterol Hepatol 24:1059-65. 2012
    ..We aimed to examine the hypothesis of whether the presence of IOM differs between patients with gastro-oesophageal reflux disease with different symptom profiles...
  7. ncbi request reprint Identification of impaired oesophageal bolus transit and clearance by secondary peristalsis in patients with non-obstructive dysphagia
    C L Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 20:980-8. 2008
    ..Multichannel intraluminal impedance identifies functional defects of oesophageal bolus clearance by secondary peristalsis in NOD patients and such defects are characterized by a longer oesophageal dwell and a prolonged clearance time...
  8. doi request reprint Utility of esophageal impedance in identifying dysmotility in patients with erosive esophagitis
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    Dis Esophagus 21:539-43. 2008
    ..MII helps identify bolus transit abnormalities not detected by conventional manometry. Combined MII-EM is clinically useful for detecting esophageal dysmotility in patients with erosive esophagitis...
  9. doi request reprint Proximal versus distal oesophageal motility as assessed by combined impedance and manometry
    C L Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, Australia
    Dig Liver Dis 41:104-9. 2009
    ..We investigated whether oesophageal motor function differs between the proximal and distal oesophagus...
  10. doi request reprint Clinical correlates of dysphagia to oesophageal dysmotility: studies using combined manometry and impedance
    C L Chen
    Department of Medicine, Buddhist Tzu Chi Medical Center and University School of Medicine, Hualien, Taiwan
    Neurogastroenterol Motil 20:611-7. 2008
    ..002). NOD patients show poor correlation between dysphagia and oesophageal motility parameters. The results suggest that, in patients with NOD, oesophageal motor dysfunction may play a limited role, if any, in the generation of dysphagia...
  11. doi request reprint Differences in oesophageal bolus transit between patients with and without erosive reflux disease
    C L Chen
    Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien 97004, Taiwan
    Dig Liver Dis 40:348-54. 2008
    ..We determined any difference in oesophageal function between reflux patients with and without erosive esophagitis by the application of concurrent manometry and impedance...
  12. ncbi request reprint Sleep symptoms and gastroesophageal reflux
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    J Clin Gastroenterol 42:13-7. 2008
    ..This study was to determine whether patients with significant nighttime heartburn had more disturbed sleep and more gastroesophageal acid reflux than those without significant nighttime heartburn...
  13. ncbi request reprint Assessment of esophageal motor function using combined multichannel intraluminal impedance and manometry in healthy volunteers: a single-center study in Taiwan
    Chien Lin Chen
    Division of Gastroenterology and Hepatology, Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    J Gastroenterol Hepatol 22:1039-43. 2007
    ..The aim of this study was to establish normative data in Chinese subjects for combined MII-EM and to correlate liquid and viscous bolus transit by impedance with esophageal contractions by manometry...
  14. ncbi request reprint Effect of acid suppression on gastric myoelectrical activity in GERD
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien 970, Taiwan
    Hepatogastroenterology 55:1353-5. 2008
    ..The study aimed to investigate whether acid suppression influences gastric myoelectrical activity in patients with reflux disease...
  15. doi request reprint Oesophageal bolus transit and clearance by secondary peristalsis in normal individuals
    Chien Lin Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, Australia
    Eur J Gastroenterol Hepatol 20:1129-35. 2008
    ..Secondary peristalsis is important for the clearance of retained refluxate or material from the oesophagus. Combined impedance and manometry can directly detect both oesophageal contraction and bolus transit...
  16. doi request reprint Evidence for oesophageal visceral hypersensitivity and aberrant symptom referral in patients with globus
    C L Chen
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, New South Wales, Australia
    Neurogastroenterol Motil 21:1142-e96. 2009
    ..The aberrant referral of oesophageal sensations in response to both mechanical and electrical stimulation supports the hypothesis that referral of symptoms to the neck might be a central phenomenon...
  17. ncbi request reprint Effects of lidocaine on esophageal secondary peristalsis in humans
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Neurogastroenterol Motil 22:606-10. 2010
    ..We aimed to investigate whether esophageal secondary peristalsis can be affected by intraluminal infusion of lidocaine into the esophagus...
  18. doi request reprint Altered sensorimotor responses to esophageal acidification in older adults with GERD
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Scand J Gastroenterol 45:1150-5. 2010
    ..This study aimed to compare the effect of intraluminal acidification on esophageal sensory perception and motor activity between older and younger patients with gastroesophageal reflux disease (GERD)...
  19. doi request reprint Disease progression in non-erosive reflux disease (NERD): impact of initial esophageal acid exposure
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital, Tzu Chi University, Hualien, Taiwan
    Dis Esophagus 23:613-7. 2010
    ..Initial pathological acid exposure does not influence the use of acid suppression; however, it does influence the progression of NERD within 5 years of follow-up...
  20. doi request reprint Effects of mosapride on esophageal secondary peristalsis in humans
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Neurogastroenterol Motil 23:606-e249. 2011
    ..We aimed to investigate the effect of a 5-HT(4) agonist mosapride on esophageal distension-induced secondary peristalsis in normal subjects...
  21. doi request reprint Control of esophageal distension-induced secondary peristalsis by the GABA(B) agonist baclofen in humans
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Neurogastroenterol Motil 23:612-e250. 2011
    ..The effects of the gamma aminobutyric acid receptor type B (GABA(B) ) agonist on secondary peristalsis remain unclear in humans. We aimed to investigate the effect of a GABA(B) agonist baclofen on esophageal secondary peristalsis...
  22. doi request reprint Evidence for altered anorectal function in irritable bowel syndrome patients with sleep disturbance
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Digestion 84:247-51. 2011
    ..Sleep dysfunction is associated with altered gastrointestinal functioning and the presence of irritable bowel syndrome (IBS). We aimed to investigate whether sleep dysfunction would influence anorectal motility in IBS patients...
  23. ncbi request reprint Clinical utility of electrogastrography and the water load test in patients with upper gastrointestinal symptoms
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    J Smooth Muscle Res 42:149-57. 2006
    ..1; P<0.05). Although electrogastrography is helpful in differentiating subgroups of patients with nausea or satiety, it cannot directly differentiate disease states such as reflux disease, gastric ulcer, and functional dyspepsia...
  24. ncbi request reprint Utility of ambulatory pH monitoring and videofluoroscopy for the evaluation of patients with globus pharyngeus
    Chien Lin Chen
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hualien, Taiwan
    Dysphagia 22:16-9. 2007
    ..Ambulatory pH monitoring seemed to be less helpful for the evaluation of globus pharyngeus without reflux-like symptoms. Pharyngeal dysfunction is detected in a substantial proportion of patients by videofluoroscopy and radiography...
  25. doi request reprint Effects of capsaicin-containing red pepper sauce suspension on esophageal secondary peristalsis in humans
    C L Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Neurogastroenterol Motil 22:1177-82, e312-3. 2010
    ..The aim of this study was to evaluate the effects of capsaicin-containing red pepper sauce suspension on esophageal secondary peristalsis in healthy adults...
  26. ncbi request reprint Comparison of esophageal motility in patients with solid dysphagia and mixed dysphagia
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    Dysphagia 20:261-5. 2005
    ..This study has shown that abnormal esophageal motility occurs slightly more in mixed dysphagia than solid dysphagia. The clinical utility of a symptomatic differentiation of patients with solid or mixed dysphagia appears to be limited...
  27. ncbi request reprint The effect of acid suppression on sleep and cardiac autonomic regulation in GERD
    Chih Hsun Yi
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Taiwan
    Hepatogastroenterology 55:1649-52. 2008
    ..The study aim was to investigate whether acid suppression changed autonomic function and subjective sleep function in patients with erosive esophagitis...
  28. ncbi request reprint Comparable effects of capsaicin-containing red pepper sauce and hydrochloric acid on secondary peristalsis in humans
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    J Gastroenterol Hepatol 28:1712-6. 2013
    ..We aimed to evaluate whether acute esophageal instillation of capsaicin and hydrochloric acid had different effects on distension-induced secondary peristalsis...
  29. ncbi request reprint Autonomic responses to heartburn induced by esophageal acid infusion
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, 707, Section 3 Chung Yang Road, Hualien 970, Taiwan
    J Gastroenterol Hepatol 19:922-6. 2004
    ..Autonomic changes associated with the perception of heartburn in patients with GERD are poorly understood...
  30. ncbi request reprint Cardiac autonomic regulation differentiates reflux disease with and without erosive esophagitis
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan
    Scand J Gastroenterol 41:1001-6. 2006
    ..The objective of this study was to investigate potential differences in autonomic function by means of heart rate variability in GERD patients with and without erosive esophagitis...
  31. doi request reprint Characterization of esophageal pressure-flow abnormalities in patients with non-obstructive dysphagia and normal manometry findings
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Taiwan
    J Gastroenterol Hepatol 28:946-53. 2013
    ..We hypothesized that patients with NOD would demonstrate evidence of high flow-resistance during bolus passage which in turn would relate to the reporting of bolus hold up perception...
  32. ncbi request reprint Utility of electrogastrography in differentiating Parkinson's disease with or without gastrointestinal symptoms: a prospective controlled study
    Chien Lin Chen
    Department of Medicine, Parkinson s Disease Clinical and Research Center, Buddhist Tzu Chi General Hospital, 707 Section 3 Chung Yang Road, Hualien 970, Taiwan
    Digestion 71:187-91. 2005
    ....
  33. ncbi request reprint Sleep dysfunction in patients with GERD: erosive versus nonerosive reflux disease
    Chih Hsun Yi
    Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan
    Am J Med Sci 334:168-70. 2007
    ..This study was undertaken to investigate whether there are differences in sleep quality among patients with erosive esophagitis, NERD, and control subjects...
  34. ncbi request reprint Decline of hepatitis B carrier rate in vaccinated and unvaccinated subjects: sixteen years after newborn vaccination program in Taiwan
    Hans Hsienhong Lin
    Department of Gastroenterology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    J Med Virol 69:471-4. 2003
    ..Also, the protection persisted for at least 15 years...
  35. ncbi request reprint Cardiac autonomic dysregulation in patients with acute hepatitis
    Kuan Yang Chen
    Department of Medicine, Taipei Municipal Jen Ai Hospital, Taipei, Taiwan
    Am J Med Sci 332:164-7. 2006
    ..Autonomic dysfunction is common in patients with chronic liver disease, but it is still unclear whether acute hepatitis coincides with alterations in autonomic functions...
  36. ncbi request reprint Electrogastrography differentiates reflux disease with or without dyspeptic symptoms
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien 970, Taiwan
    Dig Dis Sci 49:715-9. 2004
    ..01). In conclusion, this study has shown that more gastric dysrhythmias were detected in the GERD+ patients accompanied with altered perception of stomach fullness...
  37. ncbi request reprint Gastric dysrhythmias and transient sleep impairment in healthy subjects
    Chien Lin Chen
    Department of Medicine, Tzu Chi University School of Medicine and Medical Center, Hualien 970, Taiwan
    Dig Dis Sci 49:176-9. 2004
    ..The study provides a potential clue that transient sleep impairment might influence gastric myoelectrical functioning in healthy individuals...
  38. doi request reprint Colonoscopic performance in a sedated health screening population: influence of colonoscope type
    Wei Yi Lei
    Department of Medicine, Buddhist Tzu Chi General Hospital, Taiwan
    Hepatogastroenterology 59:436-9. 2012
    ..The aim of this study was to determine whether different types of colonoscopes used would affect the colonoscopic performance and sedation practice...
  39. ncbi request reprint Esophageal acid exposure in healthy adults in Taiwan: experience with pH step-up method by dual-channel pH-metry
    Chih Hsun Yi
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi University School of Medicine and Medical Center, Hualien, Taiwan
    Kaohsiung J Med Sci 21:299-303. 2005
    ..0%/1.3%. Proximal and distal acid exposure were well correlated. Results showed that neither gender nor age influenced reflux parameters and that asymptomatic volunteers might experience some gastroesophageal reflux...
  40. ncbi request reprint Effect of laparoscopic Nissen fundoplication on symptoms and gastric myoelectric activity in gastroesophageal reflux disease
    Chien Lin Chen
    Division of Gastroenterology and Hepatology, Buddhist Tzu Chi General Hospital and Medical School, Hualien, Taiwan
    J Clin Gastroenterol 40:301-5. 2006
    ..The aim of this study was to determine whether laparoscopic fundoplication alters gastric myoelectric activity. Change of digestive symptoms was also assessed...
  41. ncbi request reprint Transfer function analysis of heart rate variability correlated with gastric myoelectrical activity using a liquid nutritional meal compared to water: are they different?
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi Hospital and University, School of Medicine, Hualien 970, Taiwan, ROC
    Chin J Physiol 50:271-6. 2007
    ..05). The effects of water and Ensure on the parasympathetic and gastric electric activities are different, in which the latter is less likely to provoke an autonomic response after gastric stimulation...
  42. doi request reprint Disease characteristics in non-erosive reflux disease with and without endoscopically minimal change esophagitis: are they different?
    Wei Yi Lei
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Digestion 85:27-32. 2012
    ..NERD may include minimal change esophagitis (MCE) and no endoscopic abnormalities (MCE-). We aimed to determine whether intraesophageal acid reflux as well as esophageal motility differed between patients with and without MCE...
  43. doi request reprint Influence of intravenous propofol sedation on anorectal manometry in healthy adults
    Tso Tsai Liu
    Division of Gastroenterology and Hepatology, Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien 970, Taiwan
    Am J Med Sci 337:429-31. 2009
    ..We aimed to determine whether conscious sedation by propofol could affect anorectal manometry...
  44. ncbi request reprint Anorectal manometry in patients with chronic constipation: a single-center experience
    Tso Tsai Liu
    Division of Gastroenterology and Hepatology, Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan
    Hepatogastroenterology 55:426-9. 2008
    ..Constipation is a common complaint, but its clinical presentation varies with each individual. The aim of this study was to evaluate anorectal physiology in a prospective group of patients with chronic constipation...
  45. ncbi request reprint Minimal blood loss living donor hepatectomy
    C L Chen
    Department of Surgery, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan
    Transplantation 69:2580-6. 2000
    ..This study aims to describe the surgical technique and clinical outcomes of living donor hepatectomy with minimal blood loss requiring no blood transfusion...
  46. ncbi request reprint Magnetic resonance of the hepatic veins with angular reconstruction: application in living-related liver transplantation
    Y F Cheng
    Department of Diagnostic Radiology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Transplantation 68:267-71. 1999
    ....
  47. ncbi request reprint Liver graft regeneration in right lobe adult living donor liver transplantation
    Y F Cheng
    Department of Diagnostic Radiology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Taiwan
    Am J Transplant 9:1382-8. 2009
    ..Spleen size is a major factor contributing to portal flow and may directly trigger regeneration after transplant. Control of sufficient portal flow and adequate hepatic outflow are important factors in graft regeneration...
  48. ncbi request reprint Serotonin transporter mRNA expression is decreased by lamivudine and ribavirin and increased by interferon in immune cells
    C W Tsao
    Department of Nursing, Chung Hwa College of Medical Technology, Tainan County, Taiwan
    Scand J Immunol 63:106-15. 2006
    ..Our study indicates that these therapeutic drugs regulate 5-HTT expression, which implies that 5-HTT might be a trait marker in IFN-alpha-induced depression after hepatic therapy...
  49. ncbi request reprint A transient increase in endogeneous erythropoietin levels after paediatric liver transplantation
    S Goto
    Department of Surgery, University of Queensland, Brisbane
    Transpl Immunol 6:265-7. 1998
    ..A transient increase of endogeneous EPO following paediatric liver transplantation may be associated with extramedullary erythropoiesis in human liver grafts...
  50. doi request reprint Monitoring and assessing variation of sewage quality and microbial functional groups in a trunk sewer line
    Tzu Yi Pai
    Department of Environmental Engineering and Management, Chaoyang University of Technology, Wufeng, Taichung, 41349, Taiwan
    Environ Monit Assess 171:551-60. 2010
    ..It revealed that the degradation of organic matters, nitrification, and denitrification occurred in the trunk sewer line. But the results indicate that the condition seem favorable for nitrification...
  51. ncbi request reprint Expression of nm23 in the primary tumor and the metastatic regional lymph nodes of patients with gastric cardiac cancer
    N Y Hsu
    Division of Chest Surgery, Kaohsiung Chung Gang Memorial Hospital, Taiwan, Republic of China
    Clin Cancer Res 5:1752-7. 1999
    ..Our results show that the reduced nm23 expression in the primary tumor and in the nodal metastasis is the most useful marker for the poor prognosis of GCC following surgery...
  52. doi request reprint Effects of mosapride on secondary peristalsis in patients with ineffective esophageal motility
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    Scand J Gastroenterol 48:1363-70. 2013
    ..Despite its well-known prokinetic effect, mosapride enhances the efficiency of secondary peristalsis in patients with ineffective esophageal motility through augmenting esophageal sensitivity instead of motility...
  53. doi request reprint Evidence for neurotrophic factors associating with TRPV1 gene expression in the inflamed human esophagus
    K R Shieh
    Institute of Neuroscience, Tzu Chi University, Hualien, Taiwan
    Neurogastroenterol Motil 22:971-7, e252. 2010
    ..We aimed to determine whether expression of TRPV1 was increased in severe inflamed human esophagus, and to test the hypothesis whether the expression of TRPV1 was mediated by neurotrophic factors such as NGF and GDNF...
  54. doi request reprint Relevance of ineffective esophageal motility to secondary peristalsis in patients with gastroesophageal reflux disease
    Chien Lin Chen
    Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
    J Gastroenterol Hepatol 29:296-300. 2014
    ..The study aimed to investigate the hypothesis whether the presence of Ineffective esophageal motility would affect physiological characteristics of secondary peristalsis...
  55. doi request reprint Hemorrhagic cholecystitis after anticoagulation therapy
    Yi Ya Chen
    Department of Medicine and Pathology, Tzu Chi University, Hualien, Taiwan
    Am J Med Sci 340:338-9. 2010
    ..As demonstrated in this case, underlying malignant changes in its early stage increase the risk of bleeding concomitant with anticoagulation usage...
  56. ncbi request reprint Tuberculosis in patients with end-stage renal disease
    H C Fang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Int J Tuberc Lung Dis 8:92-7. 2004
    ..To elucidate the clinical manifestations and risk factors of the mortality rate in uraemic patients with tuberculosis (TB) infection...
  57. ncbi request reprint Dyspeptic symptoms and water load test in patients with functional dyspepsia and reflux disease
    C L Chen
    Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan
    Scand J Gastroenterol 40:28-32. 2005
    ..The aim of this study was to assess the perception to gastric distension and its relationship to specific symptoms using the water load test (WLT) in FD and gastroesophageal reflux disease (GERD)...
  58. ncbi request reprint The relationship between insulin-like growth factor-II gene Apa I polymorphism and rheumatoid arthritis
    C M Huang
    Division of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan
    Scand J Rheumatol 33:126-7. 2004
  59. ncbi request reprint Epidermal growth factor receptor (EGFR) gene Bsr I polymorphism is associated with systemic lupus erythematosus
    C M Huang
    Department of Internal Medicine, Division of Immunology and Rheumatology, China Medical University Hospital, Taichung, Taiwan
    Lupus 13:773-6. 2004
    ..02, chi2 = 5.27). However, we did not detect any association between EGFR genotype and clinical or laboratory profiles in SLE patients. The results suggest that the EGFR gene Bsr I polymorphism is related to SLE...
  60. ncbi request reprint Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin
    W S Yang
    Department of Internal Medicine, College of Public Health, National Taiwan University, Taipei 100, Taiwan
    J Clin Endocrinol Metab 86:3815-9. 2001
    ..In addition, the increase in plasma adiponectin despite the reduction of the only tissue of its own synthesis suggests that the expression of adiponectin is under feedback inhibition in obesity...
  61. ncbi request reprint Interferon-alpha reduces insulin resistance and beta-cell secretion in responders among patients with chronic hepatitis B and C
    T Y Tai
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Endocrinol 178:457-65. 2003
    ..In patients who were successfully treated with IFN-alpha, insulin sensitivity improved and their plasma glucose stayed at the same level without secreting as much insulin from islet beta-cells...
  62. ncbi request reprint Colonoscopic diagnosis of whipworm infection
    Albert Ta Chung Lin
    J Gastroenterol Hepatol 20:965-7. 2005
  63. ncbi request reprint Analysis of 24-hour esophageal pH monitoring: the effect of state of consciousness
    Chien Lin Chen
    Lynn Health Science Institute, Oklahoma University Health Sciences Center, Oklahoma City, OK 73112, USA
    Curr Gastroenterol Rep 10:258-62. 2008
    ..The significance of these findings will increase our knowledge of esophageal physiology and the pathologic mechanisms underlying gastroesophageal reflux disease...
  64. ncbi request reprint Clinical challenges and images in GI. Mycotic aneurysm of the superior mesenteric artery
    Chien Lin Chen
    Gastroenterology 131:13, 337. 2006