Albert M Wu
Affiliation: Chang Gung University
Wu A, Wu J, Singh T, Liu J, Tsai M, Gilboa Garber N. Interactions of the fucose-specific Pseudomonas aeruginosa lectin, PA-IIL, with mammalian glycoconjugates bearing polyvalent Lewis(a) and ABH blood group glycotopes. Biochimie. 2006;88:1479-92 pubmed
..Such information might be useful for the antiadhesive therapy of P. aeruginosa infections. ..
Wu A, Lisowska E, Duk M, Yang Z. Lectins as tools in glycoconjugate research. Glycoconj J. 2009;26:899-913 pubmed publisher
..Some chemical modifications of lectin ligands on the microtiter plates and blots (desialylation, Smith degradation, beta-elimination), which extend the applicability of these methods, are also described. ..
Wu A, Wu J, Tsai M, Kaltner H, Gabius H. Carbohydrate specificity of a galectin from chicken liver (CG-16). Biochem J. 2001;358:529-38 pubmed
..The binding site of CG-16 is as large as a tetrasaccharide of the beta-anomer of Gal, and is most complementary to lacto-N-tetraose and Gal(beta1-4)GlcNAc related sequences. ..
Wu A, Wu J, Herp A, Liu J. Effect of polyvalencies of glycotopes on the binding of a lectin from the edible mushroom, Agaricus bisporus. Biochem J. 2003;371:311-20 pubmed
Wu A, Wu J, Lin L, Lin S, Liu J. Binding profile of Artocarpus integrifolia agglutinin (Jacalin). Life Sci. 2003;72:2285-302 pubmed
..Gt; Man and Glc (inactive). Our finding should aid in the selection of this lectin for biological applications...
Wu A. Polyvalency of Tn (GalNAcalpha1-->Ser/Thr) glycotope as a critical factor for Vicia villosa B4 and glycoprotein interactions. FEBS Lett. 2004;562:51-8 pubmed
Wu A, Wu J, Liu J, Chen Y, Singha B, Chow L, et al
. Roles of mammalian structural units, ligand cluster and polyvalency in the Abrus precatorius agglutinin and glycoprotein recognition process. Mol Immunol. 2009;46:3427-37 pubmed publisher
..A comparison of the differential recognition factors and combining sites of APA with those of other lectins (Ricinus communis agglutinin, RCA(1) and ricin) is also illustrated...