Research Topics
Genomes and GenesSpecies | Jong Shyan WangSummaryAffiliation: Chang Gung University Country: Taiwan Publications
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Detail Information
Publications
Exercise affects platelet-promoted tumor cell adhesion and invasion to endotheliumYu Wen Chen
Graduate Institute of Basic Medical Sciences, Chang Gung University, Tao Yuan, Taiwan
Eur J Appl Physiol 105:393-401. 2009..We conclude that SE, but not ME, enhances the capacity of PNA to adhere to ECs, withstand flowing blood, and facilitate the invasion of NPCs toward ECs...
Exercise prescription and thrombogenesisJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, Tao Yuan, 333, Taiwan
J Biomed Sci 13:753-61. 2006..These findings can aid in determining appropriate exercise regimes to prevent early thrombotic events and further hinder the cardiovascular disease progression...- Systemic vascular resistance is increased and associated with accelerated arterial stiffening change in patients with chronic cervical spinal cord injuryS C Huang
Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Tao Yuan, Taiwan
Eur J Phys Rehabil Med 49:41-9. 2013..Clinical Rehabilitation Impact. SI, rather than blood pressure, reflects not only cardiovascular risk but also TPR in chronic cervical SCI... - Effect of exercise training on oxidized LDL-mediated platelet function in ratsJ S Wang
Department of Physical Therapy, Chang Gung University, Taoyuan, Taiwan ROC
Thromb Haemost 83:503-8. 2000..Results in this study demonstrate that exercise training decreases Ox-LDL-potentiated platelet activation most likely by enhancing platelet-derived NO release... - Exercise paradoxically modulates oxidized low density lipoprotein-induced adhesion molecules expression and trans-endothelial migration of monocyte in menJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, Tao Yuan, Taiwan
Thromb Haemost 94:846-52. 2005..These findings provide a new insight into the may aid the development of suitable exercise intensity enable people to prevent early atherogenesis... - Warm-up exercise suppresses platelet-eosinophil/neutrophil aggregation and platelet-promoted release of eosinophil/neutrophil oxidant products enhanced by severe exercise in menJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, Tao Yuan, Taiwan
Thromb Haemost 95:490-8. 2006..However, LIE minimizes the risk of thromboinflammation... - Hypoxic exercise training reduces senescent T-lymphocyte subsets in bloodJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, Tao Yuan 333, Taiwan
Brain Behav Immun 25:270-8. 2011..These findings can help to determine an effective hypoxic exercise regimen to minimize immune dysfunction by retarding T-lymphocyte senescence... - Effects of moderate and severe intermittent hypoxia on vascular endothelial function and haemodynamic control in sedentary menJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, Tao Yuan, 333, Taiwan
Eur J Appl Physiol 100:127-35. 2007..However, SIH but not MIH decreases anti-oxidative capacity and increases lipid peroxidation in circulation, leading to suppression of vascular endothelial function, causing impairment of vascular haemodynamics... - Effects of normoxic and hypoxic exercise regimens on cardiac, muscular, and cerebral hemodynamics suppressed by severe hypoxia in humansJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, 259 Wen Hwa 1st Rd, Kwei Shan, Tao Yuan 333, Taiwan
J Appl Physiol 109:219-29. 2010.... - Chronic intermittent hypoxia modulates eosinophil- and neutrophil-platelet aggregation and inflammatory cytokine secretion caused by strenuous exercise in menJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, Kwei Shan, Tao Yuan 333, Taiwan
J Appl Physiol 103:305-14. 2007..Furthermore, SIH simultaneously increases circulatory anti-inflammatory IL-6 and IL-10 concentrations. These findings can help to develop effective IH regimens that improve aerobic fitness and minimize risk of thromboinflammation... - Exercise modulates platelet-nasopharyngeal carcinoma cell aggregation and subsequent tissue factor and matrix metalloproteinase activitiesJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, 259 Wen Hwa 1st Rd, Kwei Shan, Tao Yuan 333, Taiwan
J Appl Physiol 103:763-70. 2007..These effects on HIE diminish after WUE. However, MIE minimizes the risk of thrombosis induced by platelet-NPC interactions... - Systemic hypoxia promotes lymphocyte apoptosis induced by oxidative stress during moderate exerciseJong Shyan Wang
Graduate Institute of Rehabilitation Science, Center for Healthy Aging Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, Tao Yuan, 333, Taiwan
Eur J Appl Physiol 108:371-82. 2010.... - Systemic hypoxia affects exercise-mediated antitumor cytotoxicity of natural killer cellsJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Healthy Aging Research, Chang Gung University, Tao Yuan, Taiwan
J Appl Physiol 107:1817-24. 2009..Moreover, exposure to 12% O(2) promotes the NK cytotoxicity with mobilizing the replicative senescent/inhibitory NKs into the bloodstream during ME... - Vitamin E suppresses enhancement of factor VIII-dependent thrombin generation by systemic hypoxiaJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, Kwei Shan, Tao Yuan, Taiwan
Stroke 40:656-9. 2009..Increased thrombin activity is an essential component of hemostatic reactions. This study elucidates how various hypoxic interventions impact endogenous thrombin generation (TG) after treatment with/without lipophilic antioxidant vitamin E... - Systemic hypoxia enhances bactericidal activities of human polymorphonuclear leuocytesJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Healthy Aging Research, Chang Gung University, Tao Yuan, Taiwan
Clin Sci (Lond) 116:805-17. 2009..However, this hypoxic effect on PMN bactericidal activity is ameliorated by pretreatment with vitamin E... - Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cellJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, Tao Yuan, Taiwan
Med Sci Sports Exerc 41:115-22. 2009..This investigation explores how various exercise regimens influence platelet-impeded cytotoxicity of NK to nasopharyngeal carcinoma cells (NPC)... - Effects of exercise intensity on lymphocyte apoptosis induced by oxidative stress in menJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, 333, Tao Yuan, Taiwan
Eur J Appl Physiol 95:290-7. 2005..However, moderate exercise attenuates lymphocyte apoptosis induced by oxidative stress, possibly by improving intracellular anti-oxidative capacity... - Effects of exercise training and deconditioning on platelet aggregation induced by alternating shear stress in menJong Shyan Wang
Graduate Institute of Rehabilitation Science, Center for Gerontological Research, Chang Gung University, Taoyuan, Taiwan
Arterioscler Thromb Vasc Biol 25:454-60. 2005..This study investigated how exercise training and deconditioning influence alternating shear-induced platelet aggregation (ASIPA) and clarify the mechanisms underlying ASIPA... - Role of chronic exercise in decreasing oxidized LDL-potentiated platelet activation by enhancing platelet-derived no release and bioactivity in ratsJ S Wang
Department of Physical Therapy, Chang Gung University, Taoyuan, Taiwan
Life Sci 66:1937-48. 2000..Moreover, exercise training decreases Ox-LDL-potentiated platelet activation most likely by enhancing platelet-derived NO release and bioactivity... - Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injuryJ S Wang
Department of Physical Therapy, Chang Gung University, Taoyun, Tawan
Thromb Haemost 84:118-23. 2000..Therefore, supplementation therapy with antioxidants may be needed for patients with SCI, especially in a strenuous arm exercise period... - Tai Chi Chuan training to enhance microcirculatory function in healthy elderly menJ S Wang
Department of Physical Therapy, Chang Gung University, Taipei, Taiwan
Arch Phys Med Rehabil 82:1176-80. 2001..To evaluate cutaneous microcirculatory function in geriatric Tai Chi Chuan (TCC) practitioners... - Effect of strenuous arm crank exercise on platelet function in patients with spinal cord injuryJong Shyan Wang
Department of Physical Therapy, Chang Gung University, Kwei Shan, Tao Yuan, Taiwan, ROC
Arch Phys Med Rehabil 83:210-6. 2002..To investigate the effects of arm crank exercise on various platelet functions and prostacyclin in individuals with spinal cord injury (SCI)... - Suppressed cutaneous endothelial vascular control and hemodynamic changes in paretic extremities with edema in the extremities of patients with hemiplegiaJong Shyan Wang
Department of Physical Therapy, Gung University, Tao Yuan, Taiwan
Arch Phys Med Rehabil 83:1017-23. 2002..To investigate peripheral circulatory function and its underlying mechanisms in the paretic upper extremity after a stroke... - Tai Chi Chuan training is associated with enhanced endothelium-dependent dilation in skin vasculature of healthy older menJong Shyan Wang
Department of Physical Therapy Chang Gung University, 259 Wen Haw 1st Road, Kwei Shan, Tao Yuan 333, Taiwan, ROC
J Am Geriatr Soc 50:1024-30. 2002..Endothelium-dependent vasodilation declines with age. This study investigated whether Tai Chi Chuan (TCC) training could enhance endothelial function in the skin vasculature of older men... - Strenuous, acute exercise affects reciprocal modulation of platelet and polymorphonuclear leukocyte activities under shear flow in menJ S Wang
Graduate Institute of Rehabilitation Science and Graduate Institute of Basic Medical Science, Chang Gung University, Taoyuan, Taiwan
J Thromb Haemost 1:2031-7. 2003..However, strenuous exercise can also simultaneously enhance the antiplatelet effect of PMNs. The finding provides a new insight into the negative feedback of PMNs against exercise-evoked platelet-related thrombotic risk... - Intense exercise increases shear-induced platelet aggregation in men through enhancement of von Willbrand factor binding, glycoprotein IIb/IIIa activation, and P-selectin expression on plateletsJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, 333 Tao Yuan, Taiwan
Eur J Appl Physiol 91:741-7. 2004.... - Moderate-intensity exercise suppresses platelet activation and polymorphonuclear leukocyte interaction with surface-adherent platelets under shear flow in menJong Shyan Wang
Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, Tao Yuan, 333, Taiwan
Thromb Haemost 91:587-94. 2004.... - Effects of exercise training and detraining on oxidized low-density lipoprotein-potentiated platelet function in menJong Shyan Wang
Graduate Institute of Rehabilitation Science and Department of Physiology, Chang Gung University, Taoyuan, Taiwan
Arch Phys Med Rehabil 85:1531-7. 2004..To investigate how exercise training and detraining affect oxidized low-density lipoprotein (Ox-LDL)-potentiated platelet function in men... - Hypoxic exercise training promotes antitumour cytotoxicity of natural killer cells in young menJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, Tao Yuan, Taiwan
Clin Sci (Lond) 121:343-53. 2011..These findings could help to determine effective hypoxic exercise regimens for improving individual aerobic capacity and simultaneously promoting the natural cytotoxicity of NKs... - Strenuous, acute exercise suppresses polymorphonuclear leukocyte respiratory burst under adherence to surface-adherent platelets in menJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung University, Kwei Shan, Tao Yuan 333, Taiwan
Thromb Haemost 92:1076-85. 2004.... - Systemic hypoxia enhances exercise-mediated bactericidal and subsequent apoptotic responses in human neutrophilsJong Shyan Wang
Graduate Institute of Rehabilitation Science, Chang Gung Univ, 259 Wen Hwa 1st Rd, Kwei Shan, Tao Yuan 333, Taiwan
J Appl Physiol 107:1213-22. 2009..Therefore, we conclude that ME at 12-15% O2 enhances bactericidal capacity and facilitates the subsequent apoptosis of neutrophils... - Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-kappaB in IL-1beta-induced VCAM-1 expression in human tracheal smooth muscle cellsChien Chun Wang
Graduate Institute of Natural Products, Department of Pharmacology, 259 Wen Hwa 1st Road, Chang Gung University, Kwei San, Tao Yuan, Taiwan
Am J Physiol Lung Cell Mol Physiol 288:L227-37. 2005..These results provide new insight into the mechanisms of IL-1beta action that cytokines may promote inflammatory responses in airway disease... - Strenuous exercise promotes shear-induced thrombin generation by increasing the shedding of procoagulant microparticles from plateletsYu Wen Chen
Graduate Institute of Biomedical Sciences, Chang Gung University, Tao Yuan, Taiwan
Thromb Haemost 104:293-301. 2010..Therefore, we conclude that strenuous exercise modestly contributes to the acceleration of shear-induced TG by increasing the release of procoagulant microparticles from platelets... 
Suppression of cerebral hemodynamics is associated with reduced functional capacity in patients with heart failureTieh Cheng Fu
Department of Physical Medicine and Rehabilitation, Gung Memorial Hospital, Keelung, Taiwan
Am J Physiol Heart Circ Physiol 300:H1545-55. 2011..We concluded that the suppression of cerebral/muscle hemodynamics during exercise is associated with ventilatory abnormality, which reduces functional capacity in patients with HF...- Role of exercise intensities in oxidized low-density lipoprotein-mediated redox status of monocyte in menJong Shyan Wang
Institute of Coaching Science, National College of Physical Education and Sports, Tao Yuan, Taiwan
J Appl Physiol 101:740-4. 2006..However, mild and moderate exercise likely protects individuals against suppression of anti-oxidative capacity of monocyte by ox-LDL... - Resveratrol protects vascular endothelial cell from ox-LDL-induced reduction in antithrombogenic activityYing Jen Chen
Department of General Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Chin J Physiol 50:22-8. 2007..The effect of ox-LDL on the NOS protein content was abrogated by pretreating EC with RSV. The results suggest that ox-LDL acts via reducing the endothelial NOS activity to suppress the antithrombogenic activity of the EC... - Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblastsShue Fen Luo
Chang Gung University, Chang Gung Memorial Hospital, Kwei San, Tao Yuan, Taiwan
Arthritis Rheum 62:105-16. 2010..To investigate the roles of MAPKs and NF-kappaB in tumor necrosis factor alpha (TNFalpha)-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human rheumatoid arthritis synovial fibroblasts (RASFs)... - Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damagesShu Er Chow
Center for General Studies, Chang Gung University, Kwei Shan, Taoyuan, Taiwan
J Appl Physiol 102:1520-7. 2007..In addition, ANG II-induced NOX activation is also attenuated. These results suggest that RSV or AST protects EC from oxLDL-induced oxidative stress by both direct ROS scavenging and inhibition of NOX activity... - ATP stimulates PGE(2)/cyclin D1-dependent VSMCs proliferation via STAT3 activation: role of PKCs-dependent NADPH oxidase/ROS generationI Ta Lee
Department of Anesthetics, Chang Gung Memorial Hospital at Linkuo and Chang Gung University, Kwei San, Tao Yuan, Taiwan
Biochem Pharmacol 85:954-64. 2013..These results suggested that ATPγS-induced cPLA2/COX-2 expression and PGE2 secretion is mediated through a PKC/NADPH oxidase/ROS/STAT3-dependent pathway in VSMCs... - Involvement of MAPKs and NF-kappaB in LPS-induced VCAM-1 expression in human tracheal smooth muscle cellsWei Ning Lin
Department of Physiology and Pharmacology, Chang Gung University, Kwei San, Tao Yuan, Taiwan
Cell Signal 19:1258-67. 2007..These results provide new insight into the mechanisms of LPS action that bacterial toxins may promote inflammatory responses in the airway disease... - Effects of exercise training and detraining on cutaneous microvascular function in man: the regulatory role of endothelium-dependent dilation in skin vasculatureJong Shyan Wang
Graduate Institute of Rehabilitation Sciences and Center for Gerontological Research, Chang Gung University, 259 Wen Hwa 1st Road, Kwei Shan, 333 Tao Yuan, Taiwan
Eur J Appl Physiol 93:429-34. 2005..The results suggest that endothelium-dependent dilation in skin vasculature is enhanced by moderate exercise training and reversed to the pretraining state with detraining... - Non-invasive cardiac index monitoring during cardiopulmonary functional testing provides additional prognostic value in patients after acute heart failureMing Feng Lee
Heart Failure Center, Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan
Int Heart J 53:364-9. 2012..02) were significant independent predictors. In conclusion, NICOM during the CPET was demonstrated to provide prognostic information in addition to traditional risk factors, biomarkers, and other well-established CPET parameters... - Absolute hypoxic exercise training enhances in vitro thrombin generation by increasing procoagulant platelet-derived microparticles under high shear stress in sedentary menYu Wen Chen
Healthy Aging Research Center, Graduate Institute of Rehabilitation Science, Chang Gung University, Tao Yuan, Taiwan
Clin Sci (Lond) 124:639-49. 2013..These findings provide new insights into how exercise training under a hypoxic condition influences the risk of thrombosis associated with stenotic arteries... - Systemic hypoxia affects cardiac autonomic activity and vascular hemodynamic control modulated by physical stimulationShu Chun Huang
Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Eur J Appl Physiol 106:31-40. 2009..Moreover, the BP and cardiac autonomic responses to 12% O(2), but not 15% O(2), exposure are depressed while performing posture change and the Valsalva maneuver... - VE-Cadherin(low)α-smooth muscle actin+ component of vascular progenitor cells correlates with the coronary artery Gensini scoreChao Hung Wang
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan
Circ J 76:477-84. 2012..This study sought to determine whether the level of this subpopulation correlated with the coronary Gensini score... - Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cellsShu Er Chow
Center for General Studies, Chang Gung University, Taoyuan, Taiwan
J Cell Biochem 113:3476-85. 2012..This study indicated wogonin-induced both autophagy and apoptosis through a variety of Akt pathways and suggested modulation of autophagy might provide profoundly the potential therapeutic effect... - Hypoxic exercise training causes erythrocyte senescence and rheological dysfunction by depressed Gardos channel activityTso Yen Mao
Graduate Institute of Physical Education, National Taiwan Sport University, Taiwan
J Appl Physiol 111:382-91. 2011..Simultaneously, this intervention depresses Gardos channel-modulated erythrocyte rheological functions. Results of this study provide further insight into erythrocyte senescence induced by HE... - Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63Shu Er Chow
Center for General Studies, Chang Gung University, Taoyuan, Taiwan
Cancer Chemother Pharmacol 68:835-45. 2011..Dysregulation of GSK-3β has been implicated in tumorigenesis and cancer progression. In this study, we investigated the antitumor activity and the mechanistic action of wogonin in human nasopharyngeal carcinoma (NPC) cells... - Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylationChiang-Wen Lee
Department of Pharmacology, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
J Cell Physiol 207:174-86. 2006..These results suggest that in HTSMCs, activation of MAPK pathways, NF-kappaB, and p300 is essential for TNF-alpha-induced VCAM-1 expression... - Cyclosporine increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 systemChao Hung Wang
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, 222, Mai Chin Road, Keelung, Taiwan
Am J Physiol Regul Integr Comp Physiol 294:R811-8. 2008..In summary, CsA manipulates the mobilization of EPCs into the circulation via the CD26/DPP IV system. Short-term CsA treatment has beneficial effects on angiogenesis of ischemic tissues... - Effects of negative pressures on epithelial tight junctions and migration in wound healingChih Chin Hsu
Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
Am J Physiol Cell Physiol 299:C528-34. 2010..Negative pressure of 125 mmHg can help disassemble the cell junction to enhance epithelial migration and subsequently result in quick wound closure... - A computational modeling and analysis in cell biological dynamics using electric cell-substrate impedance sensing (ECIS)Szi Wen Chen
Department of Electronic Engineering, Chang Gung University, Tao Yuan 333, Taiwan
Biosens Bioelectron 33:196-203. 2012..Our analyses indicated that the proposed study on ECIS time series could provide a hopeful start and great potentials in both modeling and elucidating the complex mechanisms of cell biological systems... - Downregulation of p57kip² promotes cell invasion via LIMK/cofilin pathway in human nasopharyngeal carcinoma cellsShu Er Chow
Center for General Studies, Chang Gung University, Taoyuan, Taiwan
J Cell Biochem 112:3459-68. 2011.... - Accuracy of body mass index to determine obesity in women with breast cancer: an observational study of Taiwanese sampleLi Ni Liu
Graduate Institute of Clinical Medical Sciences, Chang Gung University, and Department of Surgery, Chang Gung Memorial Hospital, Tao Yuan, Taiwan
Int J Nurs Stud 47:994-1000. 2010..Excessive body fat accumulation has been associated with a worse prognosis. However, the most popular clinical indicator of obesity is not fat itself, but body mass index (BMI)... - Neuromuscular electric stimulation enhances endothelial vascular control and hemodynamic function in paretic upper extremities of patients with strokeJong-Shyan Wang
Graduate Institute of Rehabilitation Sciences and Center for Gerontological Research, Chang-Gung University, Tao-Yuan, Taipei, Taiwan 10016
Arch Phys Med Rehabil 85:1112-6. 2004..CONCLUSIONS: NMES therapy may enhance the hyperemic arterial response and endothelium-dependent dilation in skin vasculature in the paretic upper extremities of patients with stroke...