Jen Der Lin


Affiliation: Chang Gung Memorial Hospital
Country: Taiwan


  1. Lin J, Hsueh C, Chao T. Early recurrence of papillary and follicular thyroid carcinoma predicts a worse outcome. Thyroid. 2009;19:1053-9 pubmed publisher
    ..We hypothesized that an early recurrence of papillary and follicular thyroid cancers implies a rapid growth of cancer resulting in high mortality rate...
  2. request reprint
    Lin J, Chao T, Huang B, Chen S, Chang H, Hsueh C. Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytology. Thyroid. 2005;15:708-17 pubmed
    ..9% (858/21,748 cases) of patients with thyroid nodules showed histopathologically proven malignancy. Thyroid cancer detected by ultrasonography with FNAC occurred an average of 10 years younger than in prior studies. ..
  3. request reprint
    Lin J, Chao T, Chen S, Huang Y, Liou M, Hsueh C. Operative strategy for follicular thyroid cancer in risk groups stratified by pTNM staging. Surg Oncol. 2007;16:107-13 pubmed
    ..Over one-fourth of the follicular thyroid cancer patients in the high-risk group died of thyroid cancer despite aggressive treatment. ..
  4. Chiang K, Kuo S, Chen C, Ng S, Lin S, Yeh C, et al. MART-10, the vitamin D analog, is a potent drug to inhibit anaplastic thyroid cancer cell metastatic potential. Cancer Lett. 2015;369:76-85 pubmed publisher
    ..Since metastasis is the important cause of ATC-related death, our results strongly encourage the further in vivo study of MART-10 application against ATC. ..
  5. Kuo S, Chao T, Chang H, Hsueh C, Lin C, Chiang K, et al. Prognosis of papillary thyroid cancers with positive serum thyroglobulin antibody after total thyroidectomy. Asian J Surg. 2017;40:186-192 pubmed publisher
    ..202, respectively; cancer mortality, p = 0.181, p = 0.646, p = 0.656, respectively) based on the different follow-up times. Positive serum TgAb was not a risk factor, and was not associated with the prognosis of PTC patients. ..
  6. request reprint
    Lin J, Chen S, Chao T, Hsueh C, Weng H. Diagnosis and therapeutic strategy for papillary thyroid microcarcinoma. Arch Surg. 2005;140:940-5 pubmed
    ..Age, sex, and postoperative thyroglobulin level were the main prognostic factors in the high-risk group of patients with PTM. Conservative treatment of the incidental finding of PTM after suitable postoperative assessment is justified. ..
  7. Li Y, Chen S, Hseuh C, Chao T, Ho T, Lin J. Risk factors of distant metastasis in the follicular variant of papillary thyroid carcinoma. J Formos Med Assoc. 2016;115:665-71 pubmed publisher
    ..In FVPTC patients, postoperative investigation for distant metastasis may be warranted by the presence of these two positive risk factors or the absence of the one negative risk factor. ..
  8. Hsieh C, Lin H, Huang S, Hsueh C, Hsu H, Wang H, et al. Circulating epithelial cell enumeration facilitates the identification and follow-up of a patient with early stage papillary thyroid microcarcinoma: A case report. Clin Chim Acta. 2016;454:107-11 pubmed publisher
    ..CEC testing facilitates the identification of individuals at risk for cancer. Longitudinal follow-up of the CEC count may complement serum Tg testing for monitoring the status of patients with thyroid cancer. ..
  9. Wen Ko C, Szu Tah C, Feng Hsuan L, Chen Nen C, Ming Hsu W, Jen Der L. The impact of diabetes mellitus on the survival of patients with acromegaly. Endokrynol Pol. 2016;67:501-506 pubmed publisher
    ..DM and malignancy significantly influence the survival of patients with acromegaly; thus, these patients need close follow-up and appropriate therapy. (Endokrynol Pol 2016; 67 (5): 501-506). ..

More Information


  1. Lin J, Hsueh C, Chao T. Soft tissue invasion of papillary thyroid carcinoma. Clin Exp Metastasis. 2016;33:601-8 pubmed publisher
  2. Lin J, Chao T, Hsueh C, Kuo S. High recurrent rate of multicentric papillary thyroid carcinoma. Ann Surg Oncol. 2009;16:2609-16 pubmed publisher
    ..Multicentric papillary thyroid carcinoma (PTC) is not unusual in patients with PTC. However, its clinical features concerning cancer recurrence and mortality are not well described...
  3. Li Y, Tseng C, Hsu H, Lin H, Chen Y, Chen S, et al. Circulating epithelial cells as potential biomarkers for detection of recurrence in patients of papillary thyroid carcinoma with positive serum anti-thyroglobulin antibody. Clin Chim Acta. 2018;477:74-80 pubmed publisher
    ..8%) in predicting the recurrence. Our study suggests CECs testing could be a potential biomarker to identify recurrence in PTC patients with positive serum TgAb and undetectable serum Tg. ..