Jen Der Lin

Summary

Affiliation: Chang Gung Memorial Hospital
Country: Taiwan

Publications

  1. doi request reprint Early recurrence of papillary and follicular thyroid carcinoma predicts a worse outcome
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan Hsien 333, Taiwan, Republic of China
    Thyroid 19:1053-9. 2009
  2. ncbi request reprint Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytology
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, R O C
    Thyroid 15:708-17. 2005
  3. pmc Disease-specific mortality and secondary primary cancer in well-differentiated thyroid cancer with type 2 diabetes mellitus
    Szu Tah Chen
    Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, Republic of China
    PLoS ONE 8:e55179. 2013
  4. pmc Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV
    Sheng Hwu Hsieh
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, Taiwan
    Int J Endocrinol 2012:379097. 2012
  5. pmc Diabetes mellitus increased mortality rates more in gender-specific than in nongender-specific cancer patients: a retrospective study of 149,491 patients
    Wen Ko Chiou
    Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan
    Exp Diabetes Res 2012:701643. 2012
  6. doi request reprint Clinical presentations of thyroid cancer patients with multiple primary cancers
    J D Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
    J Endocrinol Invest 34:824-30. 2011
  7. ncbi request reprint Expression of sodium iodide symporter in benign and malignant human thyroid tissues
    J D Lin
    Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R O C
    Endocr Pathol 12:15-21. 2001
  8. ncbi request reprint Operative strategy for follicular thyroid cancer in risk groups stratified by pTNM staging
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, ROC
    Surg Oncol 16:107-13. 2007
  9. ncbi request reprint A 29-year retrospective review of papillary thyroid cancer in one institution
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
    Thyroid 17:535-41. 2007
  10. ncbi request reprint Papillary thyroid carcinomas with lung metastases
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
    Thyroid 14:1091-6. 2004

Detail Information

Publications80

  1. doi request reprint Early recurrence of papillary and follicular thyroid carcinoma predicts a worse outcome
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan Hsien 333, Taiwan, Republic of China
    Thyroid 19:1053-9. 2009
    ..We hypothesized that an early recurrence of papillary and follicular thyroid cancers implies a rapid growth of cancer resulting in high mortality rate...
  2. ncbi request reprint Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytology
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, R O C
    Thyroid 15:708-17. 2005
    ..9% (858/21,748 cases) of patients with thyroid nodules showed histopathologically proven malignancy. Thyroid cancer detected by ultrasonography with FNAC occurred an average of 10 years younger than in prior studies...
  3. pmc Disease-specific mortality and secondary primary cancer in well-differentiated thyroid cancer with type 2 diabetes mellitus
    Szu Tah Chen
    Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, Republic of China
    PLoS ONE 8:e55179. 2013
    ..This study investigated the effect of type 2 DM on the clinical presentations and therapeutic outcome of well-differentiated thyroid cancer...
  4. pmc Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV
    Sheng Hwu Hsieh
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, Taiwan
    Int J Endocrinol 2012:379097. 2012
    ..Male patients with TNM stages II to IV of papillary thyroid cancer need to adopt aggressive surgical and postoperative (131)I therapy...
  5. pmc Diabetes mellitus increased mortality rates more in gender-specific than in nongender-specific cancer patients: a retrospective study of 149,491 patients
    Wen Ko Chiou
    Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan
    Exp Diabetes Res 2012:701643. 2012
    ..Insufficient information is available concerning gender differences in DM with organ-specific and nonorgan-specific cancers. This study aimed to analyze gender differences in hospitalized cancer patients with or without type 2 DM...
  6. doi request reprint Clinical presentations of thyroid cancer patients with multiple primary cancers
    J D Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
    J Endocrinol Invest 34:824-30. 2011
    ..In thyroid cancer patients with multiple primary cancers, primary cancers tend to be more aggressive...
  7. ncbi request reprint Expression of sodium iodide symporter in benign and malignant human thyroid tissues
    J D Lin
    Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R O C
    Endocr Pathol 12:15-21. 2001
    ..Determination of the reason for discrepancies in the expression of hNIS in in vivo and in vitro studies will require further investigation...
  8. ncbi request reprint Operative strategy for follicular thyroid cancer in risk groups stratified by pTNM staging
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, ROC
    Surg Oncol 16:107-13. 2007
    ..Over one-fourth of the follicular thyroid cancer patients in the high-risk group died of thyroid cancer despite aggressive treatment...
  9. ncbi request reprint A 29-year retrospective review of papillary thyroid cancer in one institution
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
    Thyroid 17:535-41. 2007
    ..The goal of this study was to determine whether conservative surgical therapy had been adequate for low-risk patients with papillary thyroid cancer...
  10. ncbi request reprint Papillary thyroid carcinomas with lung metastases
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
    Thyroid 14:1091-6. 2004
    ..Limited information is available on the presentation, treatment outcomes, and prognostic factors of papillary thyroid carcinoma with lung metastases...
  11. ncbi request reprint Cystic change in thyroid cancer
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan
    ANZ J Surg 77:450-4. 2007
    ..To determine the incidence of cystic change of thyroid cancer detected by ultrasonography and to compare the diagnostic accuracy of fine-needle aspiration cytology (FNAC) postultrasonography in solid and cystic thyroid nodules...
  12. ncbi request reprint Diagnosis and therapeutic strategy for papillary thyroid microcarcinoma
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University, Chang Gung Memorial Hospital, 5 Fu Shin Street, Kweishan County, Taoyuan Hsien, Linkou, Taiwan
    Arch Surg 140:940-5. 2005
    ..Total thyroidectomy followed by radioactive iodine I 131 treatment is effective in papillary thyroid microcarcinoma (PTM) with lymph node or extrathyroid invasion...
  13. ncbi request reprint Vascular endothelial growth factor in thyroid cancers
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University, Taiwan, Republic of China
    Cancer Biother Radiopharm 20:648-61. 2005
    ..Future studies focused on recombinant human anti-VEGF research involving patients with advanced thyroid cancer, and investigation of the protection of high-risk patients by using novel antiangiogenic vaccines, are warranted...
  14. ncbi request reprint Papillary thyroid carcinoma with lymph node metastases
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, People s Republic of China
    Growth Factors 25:41-9. 2007
    ..In conclusion, aggressive surgical procedures performed by experienced surgeons or postoperative radioactive iodine therapy to minimize local recurrence of LN for PTC patients with high risk...
  15. ncbi request reprint Association of hematological factors with components of the metabolic syndrome in older and younger adults
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan, Taoyuan Hsien, Taiwan
    Aging Clin Exp Res 18:477-84. 2006
    ..This study retrospectively examined the characteristics of metabolic syndrome in an aged population and assessed the risk factors for these subjects...
  16. ncbi request reprint Clinical characteristics of poorly differentiated thyroid carcinomas compared with those of classical papillary thyroid carcinomas
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, ROC
    Clin Endocrinol (Oxf) 66:224-8. 2007
    ....
  17. ncbi request reprint Thyroglobulin and human thyroid cancer
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan Hsien, Taiwan, ROC
    Clin Chim Acta 388:15-21. 2008
    ..The detection of Tg by biochemical and molecular means has important diagnostic significance due to its pleiotropic roles in identification of tissue of thyroid origin, differentiation, and post-operative follow-up...
  18. doi request reprint Increased incidence of papillary thyroid microcarcinoma with decreased tumor size of thyroid cancer
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, ROC
    Med Oncol 27:510-8. 2010
    ..One-third of PTMC with clinically aggressive behavior cannot be treated as indolent disease. Invasive tumor markers or larger tumor size are useful to predict tumor recurrence or distant metastasis for PTMC...
  19. ncbi request reprint Comparison of three-dimensional anthropometric body surface scanning to waist-hip ratio and body mass index in correlation with metabolic risk factors
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan Hsien, Taiwan, R O C
    J Clin Epidemiol 55:757-66. 2002
    ..Further prospective long-term follow-up study is needed to determine the relationships of 3D body scanning data and HI to blood pressure, blood glucose, lipid, and uric acid levels...
  20. ncbi request reprint Serum uric acid and leptin levels in metabolic syndrome: a quandary over the role of uric acid
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan, Taoyuan Hsien, Taiwan 333, ROC
    Metabolism 56:751-6. 2007
    ..In conclusion, serum UA is significantly related to risk factors of metabolic syndrome except for blood glucose. Waist-to-hip ratio and HOMA-IR were statistically different in subjects with and without metabolic syndrome...
  21. doi request reprint High recurrent rate of multicentric papillary thyroid carcinoma
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan County, Taoyuan Hsien, Taiwan ROC
    Ann Surg Oncol 16:2609-16. 2009
    ..Multicentric papillary thyroid carcinoma (PTC) is not unusual in patients with PTC. However, its clinical features concerning cancer recurrence and mortality are not well described...
  22. doi request reprint Therapeutic outcomes of papillary thyroid carcinomas with tumors more advanced than T1N0M0
    Jen Der Lin
    Department of Internal Medicine, Chang Gung University, Taiwan, ROC
    Radiother Oncol 89:97-104. 2008
    ..This retrospective study analyzed the role of total or near-total thyroidectomy and adjuvant radioactive iodide ((131)I) therapy in papillary thyroid carcinoma patients with disease more advanced than T1N0M0...
  23. doi request reprint Incidental and nonincidental papillary thyroid microcarcinoma
    Jen Der Lin
    Department of Internal Medicine, CDivision of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, ROC
    Ann Surg Oncol 15:2287-92. 2008
    ..Aggressive surgical treatment with (131)I therapy is indicated for nonincidental PTMC...
  24. ncbi request reprint Application of three-dimensional body scanner: observation of prevalence of metabolic syndrome
    J D Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan Hsien, Taiwan, ROC
    Clin Nutr 23:1313-23. 2004
    ..This retrospective cross-sectional study correlates blood pressure, blood glucose, lipid and uric acid levels with anthropometric measurements...
  25. ncbi request reprint Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasms
    Miaw Jene Liou
    Section of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taiwan
    Cancer Lett 191:223-7. 2003
    ..Moreover, further information including semi-quantitative real-time RT-PCR, is required to verify whether hTERT mRNA expression could serve as an adjunctive molecular marker for the preoperative diagnosis of thyroid malignancies...
  26. ncbi request reprint Therapeutic outcomes of papillary thyroid cancer patients in different risk groups
    Bie Yu Huang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Keelung and Linkou Chang Gung Memorial Hospital, Chang Gung University, Kweishan, Taoyuan Hsien, Taiwan, ROC
    Oncology 80:123-9. 2011
    ..The objective of this study was to determine the therapeutic outcome of papillary thyroid cancer (PTC) patients in different risk groups in one institute...
  27. ncbi request reprint Prognosis and risk stratification in young papillary thyroid carcinoma patients
    Sheng Fong Kuo
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Keelung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taiwan
    Endocr J 55:269-75. 2008
    ..Clinical classification is a good alternative classification system for predicting disease outcome in young PTC patients. Patients with confined intrathyroid lesion (<or=T2, N0, M0) may be regarded "low risk" PTC patients...
  28. doi request reprint Vascular endothelial growth factors and angiopoietins in presentations and prognosis of papillary thyroid carcinoma
    Chuen Hsueh
    Department of Pathology, Chang Gung Memorial Hospital, Linkou, Chang Gung University College of Medicine, Taiwan, R O C
    J Surg Oncol 103:395-9. 2011
    ..We expect angiogenetic factors are important in the presentation of local-regional neck or distant metastases in PTC...
  29. ncbi request reprint Correlation of the dysmetabolic risk factors with different anthropometric measurements
    Wen Ko Chiou
    Department of Industrial Design, Chang Gung University, Kweishen, Taoyuan Hsien, Taiwan
    Endocr J 52:139-48. 2005
    ..9% of the subjects. In conclusion, MI calculated from 3-D body scanner correlated with many important metabolic risk factors and associated with clinical disorders like DM, hyperlipidemia, hyperuricemia and hypertension...
  30. ncbi request reprint Clinical presentations and outcomes of surgical treatment of follicular variant of the papillary thyroid carcinomas
    Hung Yu Chang
    Division of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Kweishan County, Taoyuan Hsien, Taiwan, R O C
    Jpn J Clin Oncol 36:688-93. 2006
    ..Pre-operative diagnosis of FVPTC and its clinical course is important in identifying appropriate surgical procedures...
  31. ncbi request reprint Significance and association of serum uric acid (UA) levels with components of metabolic syndrome (MS) in the elderly
    Wen Ko Chiou
    Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, ROC
    Arch Gerontol Geriatr 55:724-8. 2012
    ..The results showed an association between serum UA levels and cardiovascular risk factors, and this finding warrants concern with regard to the aging population...
  32. ncbi request reprint Well-differentiated thyroid carcinoma with concomitant Hashimoto's thyroiditis present with less aggressive clinical stage and low recurrence
    Bie Yu Huang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Keelung and Linkou Chang Gung Memorial Hospitals, Chang Gung University, 5, Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
    Endocr Pathol 22:144-9. 2011
    ..PTC and FTC with HT presented with better clinical stage and better prognosis after same therapeutic modality. In conclusions, both PTC and FTC with HT have less aggressive clinical presentation and better prognosis...
  33. doi request reprint Therapeutic outcome and prognosis in young patients with papillary and follicular thyroid cancer
    Chung Huei Huang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu Shin St, Taoyuan Hsien, Kweishan County, Taiwan, ROC
    Pediatr Surg Int 28:489-94. 2012
    ..The aims of this study are to assess the clinical characteristics of papillary and follicular thyroid cancer in young patients and evaluate the long-term therapeutic outcomes and prognostic factors for cancer mortality and recurrence...
  34. ncbi request reprint Renal metastasis from papillary thyroid microcarcinoma
    Miaw Jene Liou
    Section of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taiwan
    Acta Otolaryngol 125:438-42. 2005
    ..The patient underwent a total thyroidectomy, radiotherapy, ablation treatment with 131I and thyroxine suppressive therapy. In conclusion, microcarcinoma cannot be ignored. Although uncommon, metastases may arise...
  35. doi request reprint Prognostic significance of Tiam1 expression in papillary thyroid carcinoma
    Chuen Hsueh
    Department of Pathology, Chang Gung Memorial Hospital, Linko, Chang Gung University College of Medicine, Kwei Shan, Taoyuan, Taiwan
    Virchows Arch 459:587-93. 2011
    ..0007). Multivariate analysis showed that Tiam1 expression was a significant and independent prognostic indicator (P=0.0090) for PTC patients. Tiam1 expression may be a novel and independent prognostic marker of PTC patients...
  36. ncbi request reprint Follicular thyroid carcinomas with lung metastases: a 23-year retrospective study
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, ROC
    Endocr J 51:219-25. 2004
    ..Older patients, higher postoperative Tg, and larger tumor size in follicular thyroid carcinoma need aggressive postoperative treatment...
  37. ncbi request reprint Significance of postoperative serum thyroglobulin levels in patients with papillary and follicular thyroid carcinomas
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
    J Surg Oncol 80:45-51. 2002
    ..This study was conducted to elucidate the significance of postoperative levels of Tg in patients with clinical presentations of papillary thyroid carcinoma, follicular thyroid carcinomas, or both...
  38. doi request reprint Prognostic evaluation of patients with multicentric papillary thyroid microcarcinoma
    Sheng Fong Kuo
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Chang Gung University, Taoyuan, Taiwan
    J Formos Med Assoc 110:511-7. 2011
    ..We hypothesize that patients with multicentric PTMC are associated with good clinical outcome, although multicentricity in papillary thyroid carcinoma may be associated with poor prognosis...
  39. ncbi request reprint The relationship between serum uric acid level and metabolic syndrome: differences by sex and age in Taiwanese
    Wen Ko Chiou
    Department of Industrial Design, Chang Gung University, Kweishan, Taoyuan, Taiwan, ROC
    J Epidemiol 20:219-24. 2010
    ..This study was performed to explore the potential value of UA level as a marker of MetS among male and female Chinese of different ages...
  40. ncbi request reprint Protective effect of physical activity independent of obesity on metabolic risk factors
    Chia Lin Li
    Dept of Health Care Management and Healthcare Databank Laboratory, Chang Gung University, Tao Yuan, Taiwan
    Int J Sport Nutr Exerc Metab 16:255-69. 2006
    ..Those participants with time spent in moderate activity more than 0.5 h each day had significantly less risk of high fasting glucose. Significantly, these associations were independent of BMI...
  41. ncbi request reprint Papillary thyroid cancer with chest metastases only detected using radioactive iodine
    Sheng Fong Kuo
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Fushing Street, Gueishan Shiang, Taoyuan, Taiwan 333, ROC
    Chang Gung Med J 27:663-72. 2004
    ..The aim of this study was to analyze the clinical features and treatment results of patients with PTC...
  42. ncbi request reprint Follicular thyroid carcinoma: From diagnosis to treatment
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, R O C
    Endocr J 53:441-8. 2006
    ..Dedifferentiated, anti-angiogenic, or gene therapies for follicular thyroid cancer with distant metastases or anaplastic transformation comprise the principal directions in future research for this cancer...
  43. ncbi request reprint Incidences of cancers in diabetic and non-diabetic hospitalized adult patients in Taiwan
    Wen Ko Chiou
    Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, and Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan Hsien, Taiwan
    Asian Pac J Cancer Prev 12:1577-81. 2011
    ..The study was to investigate the relationship between diabetes mellitus ( DM), specific cancers, age, and gender...
  44. ncbi request reprint Anaerobic thyroid abscess from a thyroid cyst after fine-needle aspiration
    Jui Hung Sun
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, 5 Fu Shin St, Kweishan County, Taoyuan Hsien, Taiwan, ROC
    Head Neck 24:84-6. 2002
    ..Anaerobic abscess formation within a thyroid cyst is rare but still possible, although aerobic thyroid abscess formation in the thyroid gland after fine-needle aspiration (FNA) has been observed in immunocompromised patients...
  45. doi request reprint Prognostic significance of pituitary tumour-transforming gene-binding factor (PBF) expression in papillary thyroid carcinoma
    Chuen Hsueh
    Department of Pathology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, 5 Fu Hsing St, Linko, Taoyuan, Taiwan
    Clin Endocrinol (Oxf) 78:303-9. 2013
    ....
  46. doi request reprint The role of radioactive iodine therapy in young patients with papillary thyroid cancer
    Sheng Fong Kuo
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
    Clin Nucl Med 34:4-6. 2009
    ..The aim of this study was to investigate the outcome of postoperative radioactive iodine (I-131) therapy in young patients with papillary thyroid carcinoma (PTC)...
  47. ncbi request reprint Sonography and fine-needle aspiration biopsy in the diagnosis of benign versus malignant nodules in patients with autoimmune thyroiditis
    Feng Hsuan Liu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan, ROC
    J Clin Ultrasound 37:487-92. 2009
    ..To correlate sonographic (US) characteristics and results of fine-needle aspiration biopsy (FNAB) of thyroid nodules in autoimmune thyroiditis (AT) with surgical pathological findings...
  48. doi request reprint Neck nodule and thyroid cancer in young without radiation exposure history
    Feng Hsuan Liu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu Shin St, Kweishan County, Taoyuan Hsien, Taiwan, ROC
    Pediatr Surg Int 25:785-8. 2009
    ..The aim of this study was to analyze the results of histopathological studies in neck masses observed in young patients. The neck masses were detected using ultrasonography and fine-needle aspiration cytology (FNAC)...
  49. pmc Utility of a histone deacetylase inhibitor (PXD101) for thyroid cancer treatment
    Shu Fu Lin
    Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, ROC
    PLoS ONE 8:e77684. 2013
    ..We evaluated the therapeutic effects of the histone deacetylase inhibitor PXD101 alone and in combination with conventional chemotherapy in treating thyroid cancer...
  50. ncbi request reprint Concurrent papillary thyroid cancer with pituitary ACTH-secreting tumor
    Sheng Fong Kuo
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Formos Med Assoc 106:330-5. 2007
    ..Finally, the patient died of pneumonia with septic shock 12 years after the diagnosis of thyroid cancer...
  51. ncbi request reprint Clinical characteristics of patients with thyrotropin-secreting pituitary adenoma
    Yung Yen Wu
    Divisions of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan
    J Formos Med Assoc 102:164-71. 2003
    ..This retrospective study analyzed the clinical characteristics of patients with this disorder treated from 1991 to 2002...
  52. ncbi request reprint Insular carcinoma: infrequent subtype of thyroid cancer with aggressive clinical course
    Tzu Chieh Chao
    Department of Surgery, Chung Gung University, Chang Gung Memorial Hospital, 5 Fu Hsing Street, Kwei Shan, Taoyuan, Taiwan
    World J Surg 28:393-6. 2004
    ..In conclusion, insular carcinomas behave aggressively, so we believe they should be treated by total thyroidectomy plus neck dissection when nodal metastases are present...
  53. doi request reprint Diagnostic and therapeutic strategies for minimally and widely invasive follicular thyroid carcinomas
    Chao Chun Huang
    Department of Internal Medicine, Chang Gung University, Taoyuan Hsien, Taiwan
    Surg Oncol 20:1-6. 2011
    ..Patients diagnosed with MIFC had responded positively to the treatment; however, for patients diagnosed with WIFC to become disease-free, early diagnosis and aggressive surgical therapies in combination with (131)I therapy were required...
  54. ncbi request reprint Surgical treatment of Hurthle cell tumors of the thyroid
    Tzu Chieh Chao
    Division of General Surgery, Department of Surgery, Chang Gung University College of Medicine, and Chang Gung Memorial Hospital at Linkou, 5 Fuhsing Street, Kweishan, Taoyuan, Taiwan
    World J Surg 29:164-8. 2005
    ..Unilateral Hurthle cell adenoma can be treated by lobectomy/isthmusectomy, and Hurthle cell carcinoma can be treated by total thyroidectomy with minimal operative morbidity...
  55. ncbi request reprint To construct a forecasting model of the anthropometric chronic disease risk factor score
    Yi Chou Chuang
    Department of Health Care Management, Chang Gung University, Taoyuan, Taiwan
    Chang Gung Med J 29:135-42. 2006
    ..This new model will help people visualize their health status and get multiple information during the process of the healthy examination...
  56. doi request reprint The effects of weekly alendronate therapy in Taiwanese males with osteoporosis
    Jawl Shan Hwang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kaohsiung, Taiwan, ROC
    J Bone Miner Metab 28:328-33. 2010
    ..Thus, alendronate showed anti-osteoporotic effects by increasing BMD and decreasing the concentrations of bone markers. The adverse events were mild and showed no significant difference between the two groups on safety assessments...
  57. ncbi request reprint Associations between the metabolic syndrome and its components, watching television and physical activity
    Chia Lin Li
    Department of Health Care Management and Healthcare Databank Laboratory, Chang Gung University, Kweishan, Tao Yuan, Taiwan
    Public Health 121:83-91. 2007
    ..To examine the associations between watching television and physical activity with the metabolic syndrome and its components...
  58. ncbi request reprint An aberrant autocrine activation of the platelet-derived growth factor alpha-receptor in follicular and papillary thyroid carcinoma cell lines
    Kuei Tien Chen
    School of Medical Technology, Chang Gung University, Taoyuan, Taiwan
    Cancer Lett 231:192-205. 2006
    ..These findings imply that autocrine activation of PDGF-alpha receptor plays a crucial role in the carcinogenesis of thyroid cells...
  59. ncbi request reprint Extramedullary plasmacytoma of the thyroid
    Sheng Fong Kuo
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Gueishan Shiang, Taoyuan, Taiwan
    N Z Med J 119:U2005. 2006
    ..Diagnosis of thyroid plasmacytoma by fine-needle aspiration cytology is typically difficult, as it was for this patient. Currently, no treatment standard exists for thyroid plasmacytoma...
  60. ncbi request reprint Adrenal incidentalomas in Taiwan: high prevalence and malignancy rate
    Chih Ching Wang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC
    Chang Gung Med J 26:34-40. 2003
    ..To define the clinical characteristics of adrenal tumors in Taiwan, we reviewed 336 pathologically proven adrenal tumors at Chang Gung Memorial Hospital in Linkou...
  61. doi request reprint Thyroid follicular neoplasm: analysis by fine needle aspiration cytology, frozen section, and histopathology
    Feng Hsuan Liu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
    Diagn Cytopathol 38:801-5. 2010
    ..9%. In conclusion, our analysis revealed high rates of accuracy when using frozen tissue sections for early diagnosis and treatment of follicular neoplasm; thus, an early decision to extent of surgery prevents a risky follow-up surgery...
  62. ncbi request reprint Characteristics of Klebsiella pneumoniae bacteremia in community-acquired and nosocomial infections in diabetic patients
    Sung Sheng Tsai
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Chang Gung Med J 33:532-9. 2010
    ..pneumoniae bacteremia in diabetic patients have been rarely reported...
  63. ncbi request reprint Video-assisted open thyroid lobectomy through a small incision
    Tzu Chieh Chao
    Department of Surgery, Chang Gung University College of Medicine, and Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Surg Laparosc Endosc Percutan Tech 14:15-9. 2004
    ..8%) patients after video-assisted surgery (P = .7209). It is noteworthy that morbidity occurs in video-assisted lobectomy. The general principles of thyroid surgery should be followed to avoid the occurrence of complications...
  64. ncbi request reprint Surgical treatment of thyroid cancers with concurrent Graves disease
    Tzu Chieh Chao
    Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Ann Surg Oncol 11:407-12. 2004
    ..Thyroid cancers with concurrent Graves disease are relatively rare. Accordingly, the natural history and optimal surgical treatment of thyroid cancers with Graves disease are controversial...
  65. ncbi request reprint Gasless video-assisted total thyroidectomy in the treatment of low risk intrathyroid papillary carcinoma
    Tzu Chieh Chao
    Division of General Surgery, Department of Surgery Chang Gung University College of Medicine, Chang Gung Memorial Hospital, 5 Fuhsing Street, Kweishan, Taoyuan, Taiwan
    World J Surg 28:876-9. 2004
    ..In conclusion, gasless video-assisted total thyroidectomy is a feasible means for treating relatively small, non-invasive, clinically solitary, differentiated thyroid carcinomas...
  66. ncbi request reprint Surgical treatment of solitary thyroid nodules via fine-needle aspiration biopsy and frozen-section analysis
    Tzu Chieh Chao
    Department of Surgery, Division of General Surgery, Chang Gung Memorial Hospital at Linkou, 5 Fuhsing Street, Kweishan, Taoyuan, Taiwan
    Ann Surg Oncol 14:712-8. 2007
    ..Fine-needle aspiration biopsy (FNAB) and frozen-section analysis of managing solitary thyroid nodules continue to generate considerable controversy...
  67. doi request reprint Down-regulation of matrix metalloproteinase-7 inhibits metastasis of human anaplastic thyroid cancer cell line
    Szu Tah Chen
    Division of Endocrinology and Metabolism, Department of Internal Medicine College of Medicine, Chang Gung University, Taoyaun, Taiwan, R O C
    Clin Exp Metastasis 29:71-82. 2012
    ..To conclude, our findings suggest PB inhibits MMP-7 expression epigenetically through phosphoacetylation of histone proteins, and thereby, reduced invasive ability of an ATC thyroid cancer cell line...
  68. ncbi request reprint Sustained-release versus immediate-release glipizide for treatment of type 2 diabetes mellitus in chinese patients: A randomized, double-blind, double-dummy, parallel-group, 12-week clinical study
    Sheng Hwu Hsieh
    Department of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan
    Clin Ther 28:1318-26. 2006
    ..Few data exist that have compared sulfonylurea formulations in differing ethnic populations. Most studies of sulfonylureas have been performed in white patients with type 2 diabetes mellitus...
  69. ncbi request reprint Papillary thyroid carcinoma with different histological patterns
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Chang Gung Med J 34:23-34. 2011
    ..In addition to TNM staging, high-risk histological patterns of PTC require more aggressive follow-up examinations and postoperative adjuvant therapies...
  70. pmc Utility of a PI3K/mTOR inhibitor (NVP-BEZ235) for thyroid cancer therapy
    Shu Fu Lin
    Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, Republic of China
    PLoS ONE 7:e46726. 2012
    ..We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer...
  71. pmc A population study on the association between leisure time physical activity and self-rated health among diabetics in Taiwan
    Chia Lin Li
    Department of Health Care Management, Chang Gung University, Tao Yuan, Taiwan
    BMC Public Health 10:277. 2010
    ..The aim of this study was to explore the dose-response association between leisure time physical activity and self-rated health among diabetics in Taiwan...
  72. doi request reprint Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature
    Hui Ping Chien
    Department of Pathology, Chang Gung Memorial Hospital, No 5 Fu Shin Street, Kuei Shan, Taoyuan, Taiwan, Republic of China
    Endocr Pathol 19:274-81. 2008
    ..The distinction of true cystic lesion from cystic neoplasm is important and requires thorough sampling of the specimens...
  73. ncbi request reprint Gastric emptying function changes in patients with thyroid cancer after withdrawal of thyroid hormone therapy
    Pan Fu Kao
    Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan
    J Gastroenterol Hepatol 19:655-60. 2004
    ..In the present study the gastric emptying function of thyroid cancer patients with severe hypothyroidism of short duration was evaluated with a radionuclide solid meal gastric emptying study...
  74. doi request reprint Hypothyroid cardiac tamponade: clinical features, electrocardiography, pericardial fluid and management
    Jian Liung Wang
    Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Am J Med Sci 340:276-81. 2010
    ..This study aims to identify the patient characteristics and to propose a reasonable clinical approach for hypothyroid cardiac tamponade...
  75. ncbi request reprint Effects of clodronate on cancer growth and Ca2+ signaling of human thyroid carcinoma cell lines
    De Ming Yang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Anticancer Res 24:1617-23. 2004
    ..The results from this study implied that clodronate-mediated cell growth inhibition in slow growing thyroid cancer cells might correlate with a Ca2+ signaling pathway...
  76. ncbi request reprint Evaluation of problem-based learning education after clerkship at the Chang Gung University School of Medicine
    Yung Chang Chen
    Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei Medical College of Chang Gung University, Taoyuan, Taiwan
    Chang Gung Med J 25:758-63. 2002
    ..A questionnaire was designed to evaluate the effectiveness of this teaching method, and the results were analyzed to determine statistical significance...
  77. ncbi request reprint The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease
    Shuo Chi Chou
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan
    Altern Ther Health Med 12:34-9. 2006
    ..Other than weight reduction by dieting or physical activity, there are no well-documented medical treatments for fatty liver disease...
  78. doi request reprint Initiation of insulin glargine therapy in type 2 diabetes subjects suboptimally controlled on oral antidiabetic agents: results from the AT.LANTUS trial
    M Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 10:387-99. 2008
    ..This subgroup analysis investigated the initiation of once-daily glargine therapy in patients suboptimally controlled on multiple OADs...
  79. ncbi request reprint Hip fractures: an increasing geriatric problem in Taiwan
    Miaw Jene Liou
    Age Ageing 31:483-5. 2002