Research Topics
Species | Jen Der LinSummaryAffiliation: Chang Gung Memorial Hospital Country: Taiwan Publications
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Publications
Early recurrence of papillary and follicular thyroid carcinoma predicts a worse outcomeJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan Hsien 333, Taiwan, Republic of China
Thyroid 19:1053-9. 2009..We hypothesized that an early recurrence of papillary and follicular thyroid cancers implies a rapid growth of cancer resulting in high mortality rate...
Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytologyJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, R O C
Thyroid 15:708-17. 2005..9% (858/21,748 cases) of patients with thyroid nodules showed histopathologically proven malignancy. Thyroid cancer detected by ultrasonography with FNAC occurred an average of 10 years younger than in prior studies...- Clinical presentations of thyroid cancer patients with multiple primary cancersJ D Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
J Endocrinol Invest 34:824-30. 2011..In thyroid cancer patients with multiple primary cancers, primary cancers tend to be more aggressive... - Expression of sodium iodide symporter in benign and malignant human thyroid tissuesJ D Lin
Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R O C
Endocr Pathol 12:15-21. 2001..Determination of the reason for discrepancies in the expression of hNIS in in vivo and in vitro studies will require further investigation... - A 29-year retrospective review of papillary thyroid cancer in one institutionJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
Thyroid 17:535-41. 2007..The goal of this study was to determine whether conservative surgical therapy had been adequate for low-risk patients with papillary thyroid cancer... - Application of three-dimensional body scanner: observation of prevalence of metabolic syndromeJ D Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan Hsien, Taiwan, ROC
Clin Nutr 23:1313-23. 2004..This retrospective cross-sectional study correlates blood pressure, blood glucose, lipid and uric acid levels with anthropometric measurements... - Operative strategy for follicular thyroid cancer in risk groups stratified by pTNM stagingJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, ROC
Surg Oncol 16:107-13. 2007..Over one-fourth of the follicular thyroid cancer patients in the high-risk group died of thyroid cancer despite aggressive treatment... - Serum uric acid and leptin levels in metabolic syndrome: a quandary over the role of uric acidJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan, Taoyuan Hsien, Taiwan 333, ROC
Metabolism 56:751-6. 2007..In conclusion, serum UA is significantly related to risk factors of metabolic syndrome except for blood glucose. Waist-to-hip ratio and HOMA-IR were statistically different in subjects with and without metabolic syndrome... - Association of hematological factors with components of the metabolic syndrome in older and younger adultsJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan, Taoyuan Hsien, Taiwan
Aging Clin Exp Res 18:477-84. 2006..This study retrospectively examined the characteristics of metabolic syndrome in an aged population and assessed the risk factors for these subjects... - Clinical characteristics of poorly differentiated thyroid carcinomas compared with those of classical papillary thyroid carcinomasJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, ROC
Clin Endocrinol (Oxf) 66:224-8. 2007.... - Papillary thyroid carcinoma with lymph node metastasesJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, People s Republic of China
Growth Factors 25:41-9. 2007..In conclusion, aggressive surgical procedures performed by experienced surgeons or postoperative radioactive iodine therapy to minimize local recurrence of LN for PTC patients with high risk... - Diagnosis and therapeutic strategy for papillary thyroid microcarcinomaJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University, Chang Gung Memorial Hospital, 5 Fu Shin Street, Kweishan County, Taoyuan Hsien, Linkou, Taiwan
Arch Surg 140:940-5. 2005..Total thyroidectomy followed by radioactive iodine I 131 treatment is effective in papillary thyroid microcarcinoma (PTM) with lymph node or extrathyroid invasion... - Vascular endothelial growth factor in thyroid cancersJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University, Taiwan, Republic of China
Cancer Biother Radiopharm 20:648-61. 2005..Future studies focused on recombinant human anti-VEGF research involving patients with advanced thyroid cancer, and investigation of the protection of high-risk patients by using novel antiangiogenic vaccines, are warranted... - Thyroglobulin and human thyroid cancerJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan Hsien, Taiwan, ROC
Clin Chim Acta 388:15-21. 2008..The detection of Tg by biochemical and molecular means has important diagnostic significance due to its pleiotropic roles in identification of tissue of thyroid origin, differentiation, and post-operative follow-up... - Increased incidence of papillary thyroid microcarcinoma with decreased tumor size of thyroid cancerJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, ROC
Med Oncol 27:510-8. 2010..One-third of PTMC with clinically aggressive behavior cannot be treated as indolent disease. Invasive tumor markers or larger tumor size are useful to predict tumor recurrence or distant metastasis for PTMC... - Comparison of three-dimensional anthropometric body surface scanning to waist-hip ratio and body mass index in correlation with metabolic risk factorsJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan Hsien, Taiwan, R O C
J Clin Epidemiol 55:757-66. 2002..Further prospective long-term follow-up study is needed to determine the relationships of 3D body scanning data and HI to blood pressure, blood glucose, lipid, and uric acid levels... - High recurrent rate of multicentric papillary thyroid carcinomaJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan County, Taoyuan Hsien, Taiwan ROC
Ann Surg Oncol 16:2609-16. 2009..Multicentric papillary thyroid carcinoma (PTC) is not unusual in patients with PTC. However, its clinical features concerning cancer recurrence and mortality are not well described... - Therapeutic outcomes of papillary thyroid carcinomas with tumors more advanced than T1N0M0Jen Der Lin
Department of Internal Medicine, Chang Gung University, Taiwan, ROC
Radiother Oncol 89:97-104. 2008..This retrospective study analyzed the role of total or near-total thyroidectomy and adjuvant radioactive iodide ((131)I) therapy in papillary thyroid carcinoma patients with disease more advanced than T1N0M0... - Cystic change in thyroid cancerJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan
ANZ J Surg 77:450-4. 2007..To determine the incidence of cystic change of thyroid cancer detected by ultrasonography and to compare the diagnostic accuracy of fine-needle aspiration cytology (FNAC) postultrasonography in solid and cystic thyroid nodules... - Incidental and nonincidental papillary thyroid microcarcinomaJen Der Lin
Department of Internal Medicine, CDivision of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, ROC
Ann Surg Oncol 15:2287-92. 2008..Aggressive surgical treatment with (131)I therapy is indicated for nonincidental PTMC... - Papillary thyroid carcinomas with lung metastasesJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
Thyroid 14:1091-6. 2004..Limited information is available on the presentation, treatment outcomes, and prognostic factors of papillary thyroid carcinoma with lung metastases... - Therapeutic outcomes of papillary thyroid cancer patients in different risk groupsBie Yu Huang
Division of Endocrinology and Metabolism, Department of Internal Medicine, Keelung and Linkou Chang Gung Memorial Hospital, Chang Gung University, Kweishan, Taoyuan Hsien, Taiwan, ROC
Oncology 80:123-9. 2011..The objective of this study was to determine the therapeutic outcome of papillary thyroid cancer (PTC) patients in different risk groups in one institute... - Prognosis and risk stratification in young papillary thyroid carcinoma patientsSheng Fong Kuo
Division of Endocrinology and Metabolism, Department of Internal Medicine, Keelung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taiwan
Endocr J 55:269-75. 2008..Clinical classification is a good alternative classification system for predicting disease outcome in young PTC patients. Patients with confined intrathyroid lesion (<or=T2, N0, M0) may be regarded "low risk" PTC patients... - Vascular endothelial growth factors and angiopoietins in presentations and prognosis of papillary thyroid carcinomaChuen Hsueh
Department of Pathology, Chang Gung Memorial Hospital, Linkou, Chang Gung University College of Medicine, Taiwan, R O C
J Surg Oncol 103:395-9. 2011..We expect angiogenetic factors are important in the presentation of local-regional neck or distant metastases in PTC... - Significance and association of serum uric acid (UA) levels with components of metabolic syndrome (MS) in the elderlyWen Ko Chiou
Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, ROC
Arch Gerontol Geriatr 55:724-8. 2012..The results showed an association between serum UA levels and cardiovascular risk factors, and this finding warrants concern with regard to the aging population... - Well-differentiated thyroid carcinoma with concomitant Hashimoto's thyroiditis present with less aggressive clinical stage and low recurrenceBie Yu Huang
Division of Endocrinology and Metabolism, Department of Internal Medicine, Keelung and Linkou Chang Gung Memorial Hospitals, Chang Gung University, 5, Fu Shin St Kweishan County, Taoyuan Hsien, Taiwan, Republic of China
Endocr Pathol 22:144-9. 2011..PTC and FTC with HT presented with better clinical stage and better prognosis after same therapeutic modality. In conclusions, both PTC and FTC with HT have less aggressive clinical presentation and better prognosis... - Therapeutic outcome and prognosis in young patients with papillary and follicular thyroid cancerChung Huei Huang
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu Shin St, Taoyuan Hsien, Kweishan County, Taiwan, ROC
Pediatr Surg Int 28:489-94. 2012..The aims of this study are to assess the clinical characteristics of papillary and follicular thyroid cancer in young patients and evaluate the long-term therapeutic outcomes and prognostic factors for cancer mortality and recurrence... - Renal metastasis from papillary thyroid microcarcinomaMiaw Jene Liou
Section of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taiwan
Acta Otolaryngol 125:438-42. 2005..The patient underwent a total thyroidectomy, radiotherapy, ablation treatment with 131I and thyroxine suppressive therapy. In conclusion, microcarcinoma cannot be ignored. Although uncommon, metastases may arise... - Prognostic evaluation of patients with multicentric papillary thyroid microcarcinomaSheng Fong Kuo
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Chang Gung University, Taoyuan, Taiwan
J Formos Med Assoc 110:511-7. 2011..We hypothesize that patients with multicentric PTMC are associated with good clinical outcome, although multicentricity in papillary thyroid carcinoma may be associated with poor prognosis... - Significance of postoperative serum thyroglobulin levels in patients with papillary and follicular thyroid carcinomasJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
J Surg Oncol 80:45-51. 2002..This study was conducted to elucidate the significance of postoperative levels of Tg in patients with clinical presentations of papillary thyroid carcinoma, follicular thyroid carcinomas, or both... - Prognostic significance of Tiam1 expression in papillary thyroid carcinomaChuen Hsueh
Department of Pathology, Chang Gung Memorial Hospital, Linko, Chang Gung University College of Medicine, Kwei Shan, Taoyuan, Taiwan
Virchows Arch 459:587-93. 2011..0007). Multivariate analysis showed that Tiam1 expression was a significant and independent prognostic indicator (P=0.0090) for PTC patients. Tiam1 expression may be a novel and independent prognostic marker of PTC patients... - Incidences of cancers in diabetic and non-diabetic hospitalized adult patients in TaiwanWen Ko Chiou
Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, and Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan Hsien, Taiwan
Asian Pac J Cancer Prev 12:1577-81. 2011..The study was to investigate the relationship between diabetes mellitus ( DM), specific cancers, age, and gender... - Concurrent papillary thyroid cancer with pituitary ACTH-secreting tumorSheng Fong Kuo
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
J Formos Med Assoc 106:330-5. 2007..Finally, the patient died of pneumonia with septic shock 12 years after the diagnosis of thyroid cancer... - Clinical characteristics of patients with thyrotropin-secreting pituitary adenomaYung Yen Wu
Divisions of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan
J Formos Med Assoc 102:164-71. 2003..This retrospective study analyzed the clinical characteristics of patients with this disorder treated from 1991 to 2002... - The role of radioactive iodine therapy in young patients with papillary thyroid cancerSheng Fong Kuo
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
Clin Nucl Med 34:4-6. 2009..The aim of this study was to investigate the outcome of postoperative radioactive iodine (I-131) therapy in young patients with papillary thyroid carcinoma (PTC)... - Neck nodule and thyroid cancer in young without radiation exposure historyFeng Hsuan Liu
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu Shin St, Kweishan County, Taoyuan Hsien, Taiwan, ROC
Pediatr Surg Int 25:785-8. 2009..The aim of this study was to analyze the results of histopathological studies in neck masses observed in young patients. The neck masses were detected using ultrasonography and fine-needle aspiration cytology (FNAC)... - Surgical treatment of thyroid cancers with concurrent Graves diseaseTzu Chieh Chao
Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Ann Surg Oncol 11:407-12. 2004..Thyroid cancers with concurrent Graves disease are relatively rare. Accordingly, the natural history and optimal surgical treatment of thyroid cancers with Graves disease are controversial... - Video-assisted open thyroid lobectomy through a small incisionTzu Chieh Chao
Department of Surgery, Chang Gung University College of Medicine, and Chang Gung Memorial Hospital, Taoyuan, Taiwan
Surg Laparosc Endosc Percutan Tech 14:15-9. 2004..8%) patients after video-assisted surgery (P = .7209). It is noteworthy that morbidity occurs in video-assisted lobectomy. The general principles of thyroid surgery should be followed to avoid the occurrence of complications... - Gasless video-assisted total thyroidectomy in the treatment of low risk intrathyroid papillary carcinomaTzu Chieh Chao
Division of General Surgery, Department of Surgery Chang Gung University College of Medicine, Chang Gung Memorial Hospital, 5 Fuhsing Street, Kweishan, Taoyuan, Taiwan
World J Surg 28:876-9. 2004..In conclusion, gasless video-assisted total thyroidectomy is a feasible means for treating relatively small, non-invasive, clinically solitary, differentiated thyroid carcinomas... - Sonography and fine-needle aspiration biopsy in the diagnosis of benign versus malignant nodules in patients with autoimmune thyroiditisFeng Hsuan Liu
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan, ROC
J Clin Ultrasound 37:487-92. 2009..To correlate sonographic (US) characteristics and results of fine-needle aspiration biopsy (FNAB) of thyroid nodules in autoimmune thyroiditis (AT) with surgical pathological findings... - The relationship between serum uric acid level and metabolic syndrome: differences by sex and age in TaiwaneseWen Ko Chiou
Department of Industrial Design, Chang Gung University, Kweishan, Taoyuan, Taiwan, ROC
J Epidemiol 20:219-24. 2010..This study was performed to explore the potential value of UA level as a marker of MetS among male and female Chinese of different ages... - Prognostic significance of pituitary tumour-transforming gene-binding factor (PBF) expression in papillary thyroid carcinomaChuen Hsueh
Department of Pathology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, 5 Fu Hsing St, Linko, Taoyuan, Taiwan
Clin Endocrinol (Oxf) 78:303-9. 2013.... - Insular carcinoma: infrequent subtype of thyroid cancer with aggressive clinical courseTzu Chieh Chao
Department of Surgery, Chung Gung University, Chang Gung Memorial Hospital, 5 Fu Hsing Street, Kwei Shan, Taoyuan, Taiwan
World J Surg 28:393-6. 2004..In conclusion, insular carcinomas behave aggressively, so we believe they should be treated by total thyroidectomy plus neck dissection when nodal metastases are present... - To construct a forecasting model of the anthropometric chronic disease risk factor scoreYi Chou Chuang
Department of Health Care Management, Chang Gung University, Taoyuan, Taiwan
Chang Gung Med J 29:135-42. 2006..This new model will help people visualize their health status and get multiple information during the process of the healthy examination... - Surgical treatment of solitary thyroid nodules via fine-needle aspiration biopsy and frozen-section analysisTzu Chieh Chao
Department of Surgery, Division of General Surgery, Chang Gung Memorial Hospital at Linkou, 5 Fuhsing Street, Kweishan, Taoyuan, Taiwan
Ann Surg Oncol 14:712-8. 2007..Fine-needle aspiration biopsy (FNAB) and frozen-section analysis of managing solitary thyroid nodules continue to generate considerable controversy... - Surgical treatment of Hurthle cell tumors of the thyroidTzu Chieh Chao
Division of General Surgery, Department of Surgery, Chang Gung University College of Medicine, and Chang Gung Memorial Hospital at Linkou, 5 Fuhsing Street, Kweishan, Taoyuan, Taiwan
World J Surg 29:164-8. 2005..Unilateral Hurthle cell adenoma can be treated by lobectomy/isthmusectomy, and Hurthle cell carcinoma can be treated by total thyroidectomy with minimal operative morbidity... - Diagnostic and therapeutic strategies for minimally and widely invasive follicular thyroid carcinomasChao Chun Huang
Department of Internal Medicine, Chang Gung University, Taoyuan Hsien, Taiwan
Surg Oncol 20:1-6. 2011..Patients diagnosed with MIFC had responded positively to the treatment; however, for patients diagnosed with WIFC to become disease-free, early diagnosis and aggressive surgical therapies in combination with (131)I therapy were required... - Correlation of the dysmetabolic risk factors with different anthropometric measurementsWen-Ko Chiou
Department of Industrial Design, Chang Gung University, Kweishen, Taoyuan Hsien, Taiwan
Endocr J 52:139-48. 2005..9% of the subjects. In conclusion, MI calculated from 3-D body scanner correlated with many important metabolic risk factors and associated with clinical disorders like DM, hyperlipidemia, hyperuricemia and hypertension... - Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasmsMiaw-Jene Liou
Section of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taiwan
Cancer Lett 191:223-7. 2003..Moreover, further information including semi-quantitative real-time RT-PCR, is required to verify whether hTERT mRNA expression could serve as an adjunctive molecular marker for the preoperative diagnosis of thyroid malignancies... - Thyroid follicular neoplasm: analysis by fine needle aspiration cytology, frozen section, and histopathologyFeng Hsuan Liu
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China
Diagn Cytopathol 38:801-5. 2010..9%. In conclusion, our analysis revealed high rates of accuracy when using frozen tissue sections for early diagnosis and treatment of follicular neoplasm; thus, an early decision to extent of surgery prevents a risky follow-up surgery... - Adrenal incidentalomas in Taiwan: high prevalence and malignancy rateChih Ching Wang
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC
Chang Gung Med J 26:34-40. 2003..To define the clinical characteristics of adrenal tumors in Taiwan, we reviewed 336 pathologically proven adrenal tumors at Chang Gung Memorial Hospital in Linkou... - Follicular thyroid carcinoma: From diagnosis to treatmentJen-Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, R O C
Endocr J 53:441-8. 2006..Dedifferentiated, anti-angiogenic, or gene therapies for follicular thyroid cancer with distant metastases or anaplastic transformation comprise the principal directions in future research for this cancer... - Clinical presentations and outcomes of surgical treatment of follicular variant of the papillary thyroid carcinomasHung-Yu Chang
Division of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Kweishan County, Taoyuan Hsien, Taiwan, R.O.C
Jpn J Clin Oncol 36:688-93. 2006..In this study, FVPTC patients had a high ratio of distant metastases, few lymph node metastases and soft tissue invasion. Aggressive treatment was indicated for the high-risk FVPTC patients... 
Diabetes mellitus increased mortality rates more in gender-specific than in nongender-specific cancer patients: a retrospective study of 149,491 patientsWen Ko Chiou
Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan
Exp Diabetes Res 2012:701643. 2012..Insufficient information is available concerning gender differences in DM with organ-specific and nonorgan-specific cancers. This study aimed to analyze gender differences in hospitalized cancer patients with or without type 2 DM...- Down-regulation of matrix metalloproteinase-7 inhibits metastasis of human anaplastic thyroid cancer cell lineSzu Tah Chen
Division of Endocrinology and Metabolism, Department of Internal Medicine College of Medicine, Chang Gung University, Taoyaun, Taiwan, R O C
Clin Exp Metastasis 29:71-82. 2012..To conclude, our findings suggest PB inhibits MMP-7 expression epigenetically through phosphoacetylation of histone proteins, and thereby, reduced invasive ability of an ATC thyroid cancer cell line... - The effects of weekly alendronate therapy in Taiwanese males with osteoporosisJawl Shan Hwang
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Kaohsiung, Taiwan, ROC
J Bone Miner Metab 28:328-33. 2010..Thus, alendronate showed anti-osteoporotic effects by increasing BMD and decreasing the concentrations of bone markers. The adverse events were mild and showed no significant difference between the two groups on safety assessments... - Papillary thyroid carcinoma with different histological patternsJen Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan
Chang Gung Med J 34:23-34. 2011..In addition to TNM staging, high-risk histological patterns of PTC require more aggressive follow-up examinations and postoperative adjuvant therapies... - Associations between the metabolic syndrome and its components, watching television and physical activityChia Lin Li
Department of Health Care Management and Healthcare Databank Laboratory, Chang Gung University, Kweishan, Tao Yuan, Taiwan
Public Health 121:83-91. 2007..To examine the associations between watching television and physical activity with the metabolic syndrome and its components... - Sustained-release versus immediate-release glipizide for treatment of type 2 diabetes mellitus in chinese patients: A randomized, double-blind, double-dummy, parallel-group, 12-week clinical studySheng Hwu Hsieh
Department of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan
Clin Ther 28:1318-26. 2006..Few data exist that have compared sulfonylurea formulations in differing ethnic populations. Most studies of sulfonylureas have been performed in white patients with type 2 diabetes mellitus... - Follicular thyroid carcinomas with lung metastases: a 23-year retrospective studyJen-Der Lin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, ROC
Endocr J 51:219-25. 2004..Older patients, higher postoperative Tg, and larger tumor size in follicular thyroid carcinoma need aggressive postoperative treatment... - Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IVSheng Hwu Hsieh
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, Taiwan
Int J Endocrinol 2012:379097. 2012..Male patients with TNM stages II to IV of papillary thyroid cancer need to adopt aggressive surgical and postoperative (131)I therapy... - A population study on the association between leisure time physical activity and self-rated health among diabetics in TaiwanChia Lin Li
Department of Health Care Management, Chang Gung University, Tao Yuan, Taiwan
BMC Public Health 10:277. 2010..The aim of this study was to explore the dose-response association between leisure time physical activity and self-rated health among diabetics in Taiwan... - Characteristics of Klebsiella pneumoniae bacteremia in community-acquired and nosocomial infections in diabetic patientsSung Sheng Tsai
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan
Chang Gung Med J 33:532-9. 2010..pneumoniae bacteremia in diabetic patients have been rarely reported... - Protective effect of physical activity independent of obesity on metabolic risk factorsChia-Lin Li
Dept of Health Care Management and Healthcare Databank Laboratory, Chang Gung University, Tao-Yuan, Taiwan
Int J Sport Nutr Exerc Metab 16:255-69. 2006..Those participants with time spent in moderate activity more than 0.5 h each day had significantly less risk of high fasting glucose. Significantly, these associations were independent of BMI... - Disease-specific mortality and secondary primary cancer in well-differentiated thyroid cancer with type 2 diabetes mellitusSzu Tah Chen
Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, Republic of China
PLoS ONE 8:e55179. 2013..This study investigated the effect of type 2 DM on the clinical presentations and therapeutic outcome of well-differentiated thyroid cancer... - Utility of a PI3K/mTOR inhibitor (NVP-BEZ235) for thyroid cancer therapyShu Fu Lin
Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, Republic of China
PLoS ONE 7:e46726. 2012..We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer... - Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literatureHui Ping Chien
Department of Pathology, Chang Gung Memorial Hospital, No 5 Fu Shin Street, Kuei Shan, Taoyuan, Taiwan, Republic of China
Endocr Pathol 19:274-81. 2008..The distinction of true cystic lesion from cystic neoplasm is important and requires thorough sampling of the specimens... - Anaerobic thyroid abscess from a thyroid cyst after fine-needle aspirationJui-Hung Sun
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, 5 Fu-Shin St, Kweishan County, Taoyuan Hsien, Taiwan, ROC
Head Neck 24:84-6. 2002..We recommended careful aseptic procedure and adequate isolation processes, such as wearing a mask to avoid an unfavorable outcome as a result of a bacterial infection... - Gastric emptying function changes in patients with thyroid cancer after withdrawal of thyroid hormone therapyPan Fu Kao
Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 19:655-60. 2004..In the present study the gastric emptying function of thyroid cancer patients with severe hypothyroidism of short duration was evaluated with a radionuclide solid meal gastric emptying study... - An aberrant autocrine activation of the platelet-derived growth factor alpha-receptor in follicular and papillary thyroid carcinoma cell linesKuei-Tien Chen
School of Medical Technology, Chang Gung University, Taoyuan, Taiwan
Cancer Lett 231:192-205. 2006..These findings imply that autocrine activation of PDGF-alpha receptor plays a crucial role in the carcinogenesis of thyroid cells... - Extramedullary plasmacytoma of the thyroidSheng-Fong Kuo
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Gueishan Shiang, Taoyuan, Taiwan
N Z Med J 119:U2005. 2006..Diagnosis of thyroid plasmacytoma by fine-needle aspiration cytology is typically difficult, as it was for this patient. Currently, no treatment standard exists for thyroid plasmacytoma... - Papillary thyroid cancer with chest metastases only detected using radioactive iodineSheng-Fong Kuo
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Fushing Street, Gueishan Shiang, Taoyuan, Taiwan 333, ROC
Chang Gung Med J 27:663-72. 2004..Additionally, the low serum Tg level on the first finding of chest metastases and the small size of the primary tumor may have favorable therapeutic outcomes... - Hypothyroid cardiac tamponade: clinical features, electrocardiography, pericardial fluid and managementJian Liung Wang
Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
Am J Med Sci 340:276-81. 2010..This study aims to identify the patient characteristics and to propose a reasonable clinical approach for hypothyroid cardiac tamponade... - Effects of clodronate on cancer growth and Ca2+ signaling of human thyroid carcinoma cell linesDe-Ming Yang
Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Anticancer Res 24:1617-23. 2004..The results from this study implied that clodronate-mediated cell growth inhibition in slow growing thyroid cancer cells might correlate with a Ca2+ signaling pathway... - Evaluation of problem-based learning education after clerkship at the Chang Gung University School of MedicineYung-Chang Chen
Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei; Medical College of Chang Gung University, Taoyuan, Taiwan
Chang Gung Med J 25:758-63. 2002.... - The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver diseaseShuo-Chi Chou
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan
Altern Ther Health Med 12:34-9. 2006..Changes in uric acid levels in the 2 groups from month 2 to month 6 were statistically significant (P = .028) CONCLUSION: GP is an effective adjunct treatment to diet therapy for patients with nonalcoholic fatty liver disease... - Initiation of insulin glargine therapy in type 2 diabetes subjects suboptimally controlled on oral antidiabetic agents: results from the AT.LANTUS trialM Davies
Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Diabetes Obes Metab 10:387-99. 2008..This subgroup analysis investigated the initiation of once-daily glargine therapy in patients suboptimally controlled on multiple OADs... - Hip fractures: an increasing geriatric problem in TaiwanMiaw-Jene Liou
Age Ageing 31:483-5. 2002