Chen Hsiang Lee

Summary

Affiliation: Chang Gung Memorial Hospital
Country: Taiwan

Publications

  1. doi request reprint Comparative effectiveness of flomoxef versus carbapenems in the treatment of bacteraemia due to extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae with emphasis on minimum inhibitory concentration of flomoxef: a retrospectiv
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, 123 Ta Pei Road, Niao Sung District, Kaohsiung 833, Taiwan Chang Gung University, College of Medicine, 123 Ta Pei Road, Niao Sung District, Kaohsiung 833, Taiwan Electronic address
    Int J Antimicrob Agents 46:610-5. 2015
  2. doi request reprint Clinical and microbiologic characteristics of adult patients with recurrent bacteraemia caused by extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae
    C H Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan Chang Gung University College of Medicine, Kaohsiung, Taiwan Electronic address
    Clin Microbiol Infect 21:1105.e1-8. 2015
  3. pmc Aspirin enhances opsonophagocytosis and is associated to a lower risk for Klebsiella pneumoniae invasive syndrome
    Chen Hsiang Lee
    Department of Medical Research, Show Chwan Memorial Hospital, 6 Lukong Road, Lugang, Changhua 505, Taiwan
    BMC Infect Dis 14:47. 2014
  4. pmc Timing of initiating glycopeptide therapy for methicillin-Resistant Staphylococcus aureus bacteremia: the impact on clinical outcome
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
    ScientificWorldJournal 2013:457435. 2013
  5. ncbi request reprint Recurrent Klebsiella pneumoniae mycotic aneurysm in a diabetic patient and emergence of an extended-spectrum beta-lactamase (CTX-M-24)-containing Klebsiella pneumoniae strain after prolonged treatment with first-generation cephalosporins for mycotic aneur
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan
    Microb Drug Resist 10:359-63. 2004
  6. ncbi request reprint Risk factors for spontaneous rupture of liver abscess caused by Klebsiella pneumoniae
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan 833, ROC
    Diagn Microbiol Infect Dis 52:79-84. 2005
  7. ncbi request reprint Collateral damage of flomoxef therapy: in vivo development of porin deficiency and acquisition of blaDHA-1 leading to ertapenem resistance in a clinical isolate of Klebsiella pneumoniae producing CTX-M-3 and SHV-5 beta-lactamases
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Sung, Kaohsiung 833, Taiwan
    J Antimicrob Chemother 60:410-3. 2007
  8. pmc Microbiologic and clinical implications of bacteremia due to extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae with or without plasmid-mediated AmpC beta-lactamase DHA-1
    Chen Hsiang Lee
    Divison of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien 833, Taiwan
    Antimicrob Agents Chemother 54:5395-8. 2010
  9. ncbi request reprint Role of vascular cell adhesion molecules and leukocyte apoptosis in the lymphopenia and thrombocytopenia of patients with severe acute respiratory syndrome (SARS)
    Rong Fu Chen
    Department of Medical Research 12F12L, Chang Gung Memorial Hospital at Kaohsiung, 123 Ta Pei Road, Niau Sung, Kaohsiung 833, Taiwan, ROC
    Microbes Infect 8:122-7. 2006
  10. ncbi request reprint Treatment of ESBL-producing Klebsiella pneumoniae bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan
    J Antimicrob Chemother 58:1074-7. 2006

Collaborators

Detail Information

Publications54

  1. doi request reprint Comparative effectiveness of flomoxef versus carbapenems in the treatment of bacteraemia due to extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae with emphasis on minimum inhibitory concentration of flomoxef: a retrospectiv
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, 123 Ta Pei Road, Niao Sung District, Kaohsiung 833, Taiwan Chang Gung University, College of Medicine, 123 Ta Pei Road, Niao Sung District, Kaohsiung 833, Taiwan Electronic address
    Int J Antimicrob Agents 46:610-5. 2015
    ..Definitive flomoxef therapy appears to be inferior to carbapenems in treating ESBL-EK bacteraemia, particularly for isolates with a MICflomoxef of 2-8mg/L, even though the currently suggested MIC breakpoint of flomoxef is ≤8mg/L. ..
  2. doi request reprint Clinical and microbiologic characteristics of adult patients with recurrent bacteraemia caused by extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae
    C H Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan Chang Gung University College of Medicine, Kaohsiung, Taiwan Electronic address
    Clin Microbiol Infect 21:1105.e1-8. 2015
    ..pneumoniae isolates were fourfold or higher than the initial isolates. Recurrent bacteraemia was not uncommon in our patients with ESBL-EK bacteraemia, and most of the episodes were caused by identical strains. ..
  3. pmc Aspirin enhances opsonophagocytosis and is associated to a lower risk for Klebsiella pneumoniae invasive syndrome
    Chen Hsiang Lee
    Department of Medical Research, Show Chwan Memorial Hospital, 6 Lukong Road, Lugang, Changhua 505, Taiwan
    BMC Infect Dis 14:47. 2014
    ..Sodium salicylate (SAL) reduces the production of CPS. The study was aimed to investigate the relationship between aspirin usage and KP-mediated invasive syndrome and the effect of SAL on HV-KP...
  4. pmc Timing of initiating glycopeptide therapy for methicillin-Resistant Staphylococcus aureus bacteremia: the impact on clinical outcome
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
    ScientificWorldJournal 2013:457435. 2013
    ..The mortality rate did not decrease following administrating GP immediately after a preliminary BC indicating SLO growth. An additional research for the optimal timing for initiating GP treatment is warranted...
  5. ncbi request reprint Recurrent Klebsiella pneumoniae mycotic aneurysm in a diabetic patient and emergence of an extended-spectrum beta-lactamase (CTX-M-24)-containing Klebsiella pneumoniae strain after prolonged treatment with first-generation cephalosporins for mycotic aneur
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan
    Microb Drug Resist 10:359-63. 2004
    ..This report suggests that further observation is needed before one can draw a conclusion on the possibility of the selection of ESBL enteric organism by extensive exposure to first-generation cephalosporins...
  6. ncbi request reprint Risk factors for spontaneous rupture of liver abscess caused by Klebsiella pneumoniae
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan 833, ROC
    Diagn Microbiol Infect Dis 52:79-84. 2005
    ..Pulsed-field gel electrophoresis-generated fingerprinting of K. pneumoniae isolates from patients with SRLA revealed that these pathogens were nongenetically related...
  7. ncbi request reprint Collateral damage of flomoxef therapy: in vivo development of porin deficiency and acquisition of blaDHA-1 leading to ertapenem resistance in a clinical isolate of Klebsiella pneumoniae producing CTX-M-3 and SHV-5 beta-lactamases
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Sung, Kaohsiung 833, Taiwan
    J Antimicrob Chemother 60:410-3. 2007
    ..The study aimed to characterize the genetic basis of flomoxef and collateral ertapenem resistance in a clinical isolate of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-KP) after flomoxef exposure...
  8. pmc Microbiologic and clinical implications of bacteremia due to extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae with or without plasmid-mediated AmpC beta-lactamase DHA-1
    Chen Hsiang Lee
    Divison of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien 833, Taiwan
    Antimicrob Agents Chemother 54:5395-8. 2010
    ..Patients with fluoroquinolone exposure, diabetes mellitus, and HMPBS were at higher risk, while those with aminoglycoside exposure were at lower risk, for ESBL-PMABL-KP bacteremia...
  9. ncbi request reprint Role of vascular cell adhesion molecules and leukocyte apoptosis in the lymphopenia and thrombocytopenia of patients with severe acute respiratory syndrome (SARS)
    Rong Fu Chen
    Department of Medical Research 12F12L, Chang Gung Memorial Hospital at Kaohsiung, 123 Ta Pei Road, Niau Sung, Kaohsiung 833, Taiwan, ROC
    Microbes Infect 8:122-7. 2006
    ..However, lymphopenia may be due to enhanced cell death. Inhibition of cell adhesion and caspase-3 activation could, therefore, have prevented SARS patients from developing thrombocytopenia and lymphopenia...
  10. ncbi request reprint Treatment of ESBL-producing Klebsiella pneumoniae bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan
    J Antimicrob Chemother 58:1074-7. 2006
    ....
  11. pmc Spread of ISCR1 elements containing blaDHA-₁ and multiple antimicrobial resistance genes leading to increase of flomoxef resistance in extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China
    Antimicrob Agents Chemother 55:4058-63. 2011
    ..The cotransfer of multiple resistance genes with the ISCR1 element-carrying plasmids has a clinical impact and warrants close monitoring and further study...
  12. doi request reprint Hypermucoviscosity associated with Klebsiella pneumoniae-mediated invasive syndrome: a prospective cross-sectional study in Taiwan
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, Kaohsiung, Taiwan
    Int J Infect Dis 14:e688-92. 2010
    ..pneumoniae characteristics, including the rmpA, rmpA2, and magA genes, capsular polysaccharide (cps) K(1) or K(2) serotypes, hypermucoviscosity (HV) phenotype, and extended-spectrum beta-lactamase (ESBL) production...
  13. ncbi request reprint Underdiagnosis of urinary tract infection caused by Methylobacterium species with current standard processing of urine culture and its clinical implications
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine and Hospital Infection Control Unit, Chang Gung Memorial Hospital Kaohsiung Medical Center, Taiwan, ROC
    J Med Microbiol 53:755-9. 2004
    ....
  14. pmc Correlation of anti-fungal susceptibility with clinical outcomes in patients with cryptococcal meningitis
    Chen Hsiang Lee
    Department of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Ta Pei Road, Kaohsiung, Niao Sung District, 833, Taiwan
    BMC Infect Dis 12:361. 2012
    ..This study aimed to investigate the correlation of minimum inhibiting concentrations (MICs), obtained by broth micro-dilution, and clinical response in patients with cryptococcal meningitis...
  15. doi request reprint Five-year sequential changes in secondary antibiotic resistance of Helicobacter pylori in Taiwan
    I Ting Wu
    I Ting Wu, Seng Kee Chuah, Chih Ming Liang, Lung Sheng Lu, Yuan Hung Kuo, Yi Hao Yen, Ming Luen Hu, Yeh Pin Chou, Shih Cheng Yang, Chung Mou Kuo, Chung Huang Kuo, Shue Shian Chiou, Tsung Hui Hu, Wei Chen Tai, Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
    World J Gastroenterol 21:10669-74. 2015
    ..To determine changes in the antibiotic resistance of Helicobacter pylori (H. pylori) in southern Taiwan after failure of first-line standard triple therapy...
  16. doi request reprint Seven-Day Nonbismuth Containing Quadruple Therapy Could Achieve a Grade "A" Success Rate for First-Line Helicobacter pylori Eradication
    Wei Chen Tai
    Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Sung District, Kaohsiung City 833, Taiwan
    Biomed Res Int 2015:623732. 2015
    ..In conclusion, the results suggest that 7-day nonbismuth containing quadruple therapy could achieve a grade "A" report card for first-line H. pylori treatment. ..
  17. ncbi request reprint Community-acquired osteomyelitis caused by Chryseobacterium meningosepticum: case report and literature review
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan, Taiwan 833, ROC
    Diagn Microbiol Infect Dis 60:89-93. 2008
    ..Her chronic sclerosing osteomyelitis was cured with ciprofloxacin. English literature review found 4 cases of bone-joint infection due to C. meningosepticum. The implications of treatment with a fluoroquinolone were discussed...
  18. ncbi request reprint Splenic abscess caused by Klebsiella pneumoniae and non-Klebsiella pneumoniae in Taiwan: emphasizing risk factors for acquisition of Klebsiella pneumoniae splenic abscess
    Chen Hsiang Lee
    Division of Infectious Diseases, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, Republic of China
    Scand J Infect Dis 37:905-9. 2005
    ..4% vs 0%; p < 0.001) caused by the same pathogen. When dealing with patients suffering from K. pneumoniae splenic abscess, clinicians should work up to exclude a concomitant liver abscess caused by the same pathogen...
  19. doi request reprint Antimicrobial effects of varied combinations of meropenem, sulbactam, and colistin on a multidrug-resistant Acinetobacter baumannii isolate that caused meningitis and bacteremia
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Microb Drug Resist 14:233-7. 2008
    ..Combined use of COL with MEM and/or SUL may provide good therapeutic options, even though MEM and SUL are in vitro resistance to the MDRAB...
  20. doi request reprint Increasing trend of fluconazole-non-susceptible Cryptococcus neoformans in patients with invasive cryptococcosis: a 12-year longitudinal study
    Yi Chun Chen
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    BMC Infect Dis 15:277. 2015
    ..This study aimed to investigate the rate of fluconazole-non-susceptible Cryptococcus neoformans in Southern Taiwan for the period 2001-2012 and analyze the risk factors for acquiring it among patients with invasive cryptococcosis...
  21. pmc The influential roles of antibiotics prophylaxis in cirrhotic patients with peptic ulcer bleeding after initial endoscopic treatments
    Shih Cheng Yang
    Division of Hepato Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    PLoS ONE 9:e96394. 2014
    ..Rockall score was the predictive factor of in-hospital mortality...
  22. ncbi request reprint Splenic abscess in southern Taiwan
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, ROC
    J Microbiol Immunol Infect 37:39-44. 2004
    ..Due to the rarity of splenic abscess and the increasing number of immunocompromised patients, multicenter study is needed to determine the epidemiological features and optimal management of this disease...
  23. doi request reprint Refractory vertebral osteomyelitis due to CTX-M-14-producing Escherichia coli at ertapenem treatment in a patient with a coexisting urinary tract infection caused by the same pathogen
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan
    Int J Infect Dis 14:e183-6. 2010
    ..coli in this case to the suboptimal ertapenem concentration in the inflammatory bone tissue of the host...
  24. ncbi request reprint Unusual femoral artery mycotic aneurysm complicated by infective spondylitis
    Wei Che Lin
    Department of Diagnostic Radiology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung Hsiang, Kasohsiung Hsien, Taiwan, 833, Republic of China
    Emerg Radiol 15:207-10. 2008
    ..This rare complication could be underdiagnosed in the absence of a more extended field of imaging view such as is provided by computed tomography...
  25. pmc Comparison of serological response to doxycycline versus benzathine penicillin G in the treatment of early syphilis in HIV-infected patients: a multi-center observational study
    Jen Chih Tsai
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan Department of Internal Medicine, Tzu Chi Hospital and Tzu Chi University College of Medicine, Hua lien, Taiwan
    PLoS ONE 9:e109813. 2014
    ....
  26. doi request reprint Clinical characteristics and risk factors for mortality in patients with meningitis caused by Staphylococcus aureus and vancomycin minimal inhibitory concentrations against these isolates
    Wen Chi Huang
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan
    J Microbiol Immunol Infect 43:470-7. 2010
    ..aureus meningitis, to identify the risk factors for mortality in the affected patients, and to determine the levels of vancomycin minimal inhibitory concentrations (MICs) against these pathogens...
  27. doi request reprint A melioidosis patient presenting with brainstem signs in the emergency department
    Chia Te Kung
    Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Emerg Med 44:e9-12. 2013
    ..Neurological abnormalities in melioidosis are rare but may manifest as an acute stroke, and in the emergency department (ED), an inappropriate stroke treatment may threaten a patient's life...
  28. doi request reprint Accurate detection of binary toxin producer from Clostridium difficile by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    Shu Fang Kuo
    Department of Laboratory Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Diagn Microbiol Infect Dis 83:229-31. 2015
    ..The rate of accurate differentiation between these 2 genotypes was 100% by 6-peak cluster analysis of spectra generated by Bruker Biotyper matrix-assisted laser desorption ionization/time-of-flight mass spectrometry. ..
  29. pmc Quinolone-containing therapies in the eradication of Helicobacter pylori
    Seng Kee Chuah
    Division of Hepato Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung 833, Taiwan
    Biomed Res Int 2014:151543. 2014
    ..Molecular methods are achieved by using a real-time polymerase chain reaction to detect the presence of a gyrA mutation, which is predictive of treatment failure with quinolones-containing triple therapy. ..
  30. pmc The clinical and bacteriological factors for optimal levofloxacin-containing triple therapy in second-line Helicobacter pylori eradication
    Wei Chen Tai
    Division of Hepatogastroenterology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    PLoS ONE 9:e105822. 2014
    ..This study suggests that tailored levofloxacin-containing therapy should be administered only for patients with susceptible strains because it can achieve >90% success rates...
  31. doi request reprint Teicoplanin therapy for MRSA bacteraemia: a retrospective study emphasizing the importance of maintenance dosing in improving clinical outcomes
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Antimicrob Chemother 70:257-63. 2015
    ..To study the relationship between teicoplanin maintenance dosing and clinical outcomes in adults with MRSA bacteraemia...
  32. ncbi request reprint Unusual presentation of infected vertebroplasty with delayed cement dislodgment in an immunocompromised patient: case report and review of literature
    Wei Che Lin
    Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta Pei Road Niao Sung Hsiang, Kaohsiung 83305, Taiwan
    Cardiovasc Intervent Radiol 31:S231-5. 2008
    ..We discuss the significance of this case and compare it with 7 others found in the literature...
  33. pmc The outcome of prophylactic intravenous cefazolin and ceftriaxone in cirrhotic patients at different clinical stages of disease after endoscopic interventions for acute variceal hemorrhage
    Cheng Kun Wu
    Division of Hepato Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    PLoS ONE 8:e61666. 2013
    ..Prophylactic intravenous ceftriaxone yields better outcome among Child's B and C patients...
  34. doi request reprint Imaging spectrum of thoracic melioidosis
    Sheung Fat Ko
    Department of Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    J Thorac Imaging 28:W43-8. 2013
    ..In this pictorial essay, we provide an illustrated review and conceptual framework of the protean imaging features of this infection, along with a brief description of its clinical manifestations and demographic features...
  35. ncbi request reprint Acute Q fever presenting as antiphospholipid syndrome, pneumonia, and acalculous cholecystitis and masquerading as Mycoplasma pneumoniae and hepatitis C viral infections
    Chen Hsiang Lee
    Department of Internal Medicine, Chang Gung University Medical College, Kaohsiung, Taiwan
    Jpn J Infect Dis 64:525-7. 2011
    ..To avoid incorrect diagnosis and subsequent delays in appropriate treatment of Q fever patients, the possibility that Q fever can masquerade as other infections or as an autoimmune disease should be kept in mind...
  36. pmc Antibiotic consumption and healthcare-associated infections caused by multidrug-resistant gram-negative bacilli at a large medical center in Taiwan from 2002 to 2009: implicating the importance of antibiotic stewardship
    I Ling Chen
    Department of Pharmacology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    PLoS ONE 8:e65621. 2013
    ....
  37. doi request reprint Clinical characteristics and risk factors for fatality in patients with bloodstream infections caused by glucose non-fermenting gram-negative Bacilli
    Tzu Yao Chang
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Microbiol Immunol Infect 43:233-9. 2010
    ..Our objectives were to evaluate the epidemiology and clinical characteristics of GNF-GNB BSIs, and to identify risk factors for fatality...
  38. ncbi request reprint Right arm pyomyositis and necrotizing fasciitis complicated with subcutaneous emphysema and pneumomediastinum in a patient with diabetes mellitus and iatrogenic Cushing syndrome
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, Republic of China
    South Med J 97:1104-6. 2004
    ..The patient improved-with antimicrobial therapy and localized debridement and fasciotomy over her right arm...
  39. doi request reprint Pulmonary nocardiosis in southern Taiwan
    Yi Chun Chen
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    J Microbiol Immunol Infect 46:441-7. 2013
    ..Nocardiosis mainly affects immunocompromised patients. The objectives of this study were to better understand the epidemiologic, demographic, clinical, and laboratory information in patients with pulmonary nocardiosis in southern Taiwan...
  40. doi request reprint Initially unrecognized dementia in a young man with neurosyphilis
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Neurologist 15:95-7. 2009
    ..If neurosyphilis is diagnosed early enough, a timely effective treatment may not only prevent further progression of the disease but also allow complete recovery...
  41. ncbi request reprint Coinfection with leptospirosis and scrub typhus in Taiwanese patients
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine Kaohsiung, Taiwan, Republic of China
    Am J Trop Med Hyg 77:525-7. 2007
    ..Lack of knowledge of coinfection may jeopardize the health of affected patients. Our study serves as a reminder of potential coinfection and provides clues for its detection...
  42. ncbi request reprint Hemophagocytic syndrome in a patient with acquired immunodeficiency syndrome and acute disseminated penicilliosis
    Sung nan Pei
    Divisions of Infectious Diseases and Hematology Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta Pei Road, Kaohsiung, Taiwan, Republic of China
    Am J Trop Med Hyg 78:11-3. 2008
    ..This awareness may alert clinicians to potential penicilliosis marneffei in HIV-positive patients, therefore making early diagnosis and timely effective treatment of the infectious disease possible...
  43. ncbi request reprint Immune reconstitution syndrome in a patient with AIDS with paradoxically deteriorating brain tuberculoma
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China
    AIDS Patient Care STDS 21:234-9. 2007
    ....
  44. doi request reprint Comparisons of dengue illness classified based on the 1997 and 2009 World Health Organization dengue classification schemes
    Ching Yen Tsai
    Division of Infectious Diseases, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    J Microbiol Immunol Infect 46:271-81. 2013
    ..We compared differences in clinical/laboratory features between patients separately classified as DF/DHF and in Group A/B/C...
  45. ncbi request reprint Clinical and microbiological characteristics of mycotic aneurysms in a medical center in southern Taiwan
    Pao Jen Hsu
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan
    J Microbiol Immunol Infect 41:318-24. 2008
    ..Mycotic aneurysm poses a high risk of mortality. This study evaluated the demographic and clinical characteristics and outcomes of hospitalized patients with mycotic aneurysm...
  46. ncbi request reprint Abdominal tuberculosis: analysis of clinical features and outcome of adult patients in southern Taiwan
    Ming Luen Hu
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Chang Gung Med J 32:509-16. 2009
    ..The study was conducted at the Chang Gung Memorial Hospital-Kaohsiung, Taiwan...
  47. pmc Prosthetic joint infection caused by Mycobacterium alvei in an elderly patient
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, 123 Ta Pei Road, Niao Sung District, Kaohsiung 833, Taiwan
    J Clin Microbiol 49:3096-8. 2011
    ..The pathogen was susceptible to linezolid, amikacin, ciprofloxacin, tigecycline, and trimethoprim-sulfamethoxazole. The clinical implications are discussed...
  48. doi request reprint Are antibiotics beneficial to children suffering from enterovirus infection complicated with a high C-reactive protein level?
    Kuang Che Kuo
    Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Int J Infect Dis 25:100-3. 2014
    ..The aim of this study was to delineate how effective antibiotics are for children suffering from enterovirus infection complicated with a high CRP level...
  49. ncbi request reprint In vivo selection of OmpK35-deficient mutant after cefuroxime therapy for primary liver abscess caused by Klebsiella pneumoniae
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine 123 Ta Pei Road, Niao Sung, Kaohsiung 833, Taiwan
    J Antimicrob Chemother 58:857-60. 2006
    ..The aim of the study was to characterize the genetic basis of beta-lactam resistance developed in clinical isolates of Klebsiella pneumoniae after exposure to cefuroxime...
  50. pmc One dose versus three weekly doses of benzathine penicillin G for patients co-infected with HIV and early syphilis: a multicenter, prospective observational study
    Chia Jui Yang
    Department of Internal Medicine, Far East Memorial Hospital, New Taipei City, Taiwan
    PLoS ONE 9:e109667. 2014
    ....
  51. pmc Refractures in cemented vertebrae after percutaneous vertebroplasty: a retrospective analysis
    Wei Che Lin
    Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung, 83305, Taiwan
    Eur Spine J 17:592-9. 2008
    ..01). In conclusion, refractures of cemented vertebrae after vertebroplasty occurred in 63% of osteoporotic patients. Significant anterior vertebral height restoration increases the risk of subsequent fracture in cemented vertebrae...
  52. ncbi request reprint Tuberculous ankle versus pyogenic septic ankle arthritis: a retrospective comparison
    Shih Hao Chen
    Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University, Kaohsiung, Taiwan
    Jpn J Infect Dis 64:139-42. 2011
    ..1; 95% confidence interval=1.6‒779.8; P=0.02) by multiple logistic regression analysis. Awareness of these factors is essential for the accurate and timely diagnosis of ankle TB...
  53. ncbi request reprint Altered p38 mitogen-activated protein kinase expression in different leukocytes with increment of immunosuppressive mediators in patients with severe acute respiratory syndrome
    Chen Hsiang Lee
    Department of Internal Medicine, Chang Gung Memorial Hospital, 123 Ta Pei Road, Niau Sung, Kaohsiung 833, Taiwan
    J Immunol 172:7841-7. 2004
    ..These results suggest that regulation of TGF-beta and PGE(2) production and MAPKs activation in different leukocytes may be considered while developing therapeutics for the SARS treatment...
  54. doi request reprint Acute melioid community-acquired pneumonia
    Chia Te Kung
    Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Int J Infect Dis 15:e627-30. 2011
    ....