Jui Yang Lai

Summary

Affiliation: Chang Gung University
Country: Taiwan

Publications

  1. ncbi Functional assessment of cross-linked porous gelatin hydrogels for bioengineered cell sheet carriers
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    Biomacromolecules 11:1387-97. 2010
  2. ncbi Characterization of cross-linked porous gelatin carriers and their interaction with corneal endothelium: biopolymer concentration effect
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan, Republic of China
    PLoS ONE 8:e54058. 2013
  3. ncbi Corneal Stromal Cell Growth on Gelatin/Chondroitin Sulfate Scaffolds Modified at Different NHS/EDC Molar Ratios
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan
    Int J Mol Sci 14:2036-55. 2013
  4. ncbi Adhesion, phenotypic expression, and biosynthetic capacity of corneal keratocytes on surfaces coated with hyaluronic acid of different molecular weights
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan, ROC
    Acta Biomater 8:1068-79. 2012
  5. ncbi Biocompatibility of genipin and glutaraldehyde cross-linked chitosan materials in the anterior chamber of the eye
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan E Mail Tel 886 3 211 8800 ext 3598 Biomedical Engineering Research Center, Chang Gung University, Taoyuan 33302, Taiwan Molecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan
    Int J Mol Sci 13:10970-85. 2012
  6. ncbi Nanoscale modification of porous gelatin scaffolds with chondroitin sulfate for corneal stromal tissue engineering
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan, Republic of China
    Int J Nanomedicine 7:1101-14. 2012
  7. ncbi A gelatin-g-poly(N-isopropylacrylamide) biodegradable in situ gelling delivery system for the intracameral administration of pilocarpine
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    Biomaterials 33:2372-87. 2012
  8. ncbi Biocompatibility of chemically cross-linked gelatin hydrogels for ophthalmic use
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, 33302, Taoyuan, Taiwan, Republic of China
    J Mater Sci Mater Med 21:1899-911. 2010
  9. ncbi Ocular biocompatibility of carbodiimide cross-linked hyaluronic acid hydrogels for cell sheet delivery carriers
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    J Biomater Sci Polym Ed 21:359-76. 2010
  10. ncbi Low Bloom strength gelatin as a carrier for potential use in retinal sheet encapsulation and transplantation
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    Biomacromolecules 10:310-9. 2009

Collaborators

  • Ko Hua Chen
  • Ging Ho Hsiue
  • Pao Hsien Chu
  • David Hui Kang Ma
  • Hung Chi Jesse Chen
  • Jan Kan Chen
  • Chi Chin Sun
  • Hsiao Lei Lei
  • Ken Kuo Lin
  • Su Fang Wang
  • Unique Yang
  • Yi Ju Ho
  • Lung Kung Yeh
  • Szu Tzu Yu
  • Jia ye Liu
  • Grace Chang
  • Ming Hui Sun
  • Wan Chen Ku
  • Hsiao Yun Cheng
  • Lung Kun Yeh
  • Chen Chi Tsai
  • Hsiang Ling Chen
  • Chih Chun Chen
  • Ming Tse Kuo
  • Yueh Ju Tsai

Detail Information

Publications17

  1. ncbi Functional assessment of cross-linked porous gelatin hydrogels for bioengineered cell sheet carriers
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    Biomacromolecules 11:1387-97. 2010
    ..Our findings suggest that the gelatin discs with enlarged pore structure have potential as cell sheet carriers for intraocular delivery and corneal tissue engineering...
  2. ncbi Characterization of cross-linked porous gelatin carriers and their interaction with corneal endothelium: biopolymer concentration effect
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan, Republic of China
    PLoS ONE 8:e54058. 2013
    ..It is concluded that the characteristics of cross-linked porous gelatin hydrogel carriers and their triggered biological responses are in relation to biopolymer concentration effects...
  3. ncbi Corneal Stromal Cell Growth on Gelatin/Chondroitin Sulfate Scaffolds Modified at Different NHS/EDC Molar Ratios
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan
    Int J Mol Sci 14:2036-55. 2013
    ..These findings suggest that a positive correlation is noticed between the NHS to EDC molar ratio and the CS content in the biopolymer matrices, thereby greatly affecting the corneal stromal cell growth...
  4. ncbi Adhesion, phenotypic expression, and biosynthetic capacity of corneal keratocytes on surfaces coated with hyaluronic acid of different molecular weights
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan, ROC
    Acta Biomater 8:1068-79. 2012
    ..It is concluded that the cultured RCKs on surfaces coated with HA of different MWs can sense ECM cues, and the multicellular spheroids may potentially be used for corneal stromal tissue engineering applications...
  5. ncbi Biocompatibility of genipin and glutaraldehyde cross-linked chitosan materials in the anterior chamber of the eye
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan 33302, Taiwan E Mail Tel 886 3 211 8800 ext 3598 Biomedical Engineering Research Center, Chang Gung University, Taoyuan 33302, Taiwan Molecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan
    Int J Mol Sci 13:10970-85. 2012
    ..In summary, the intracameral tissue response to the chemically modified chitosan materials strongly depends on the selection of cross-linking agents...
  6. ncbi Nanoscale modification of porous gelatin scaffolds with chondroitin sulfate for corneal stromal tissue engineering
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan, Republic of China
    Int J Nanomedicine 7:1101-14. 2012
    ..Porous membranes with a CS content of 0.112 ± 0.003 nmol per 10 mg scaffold may hold potential for use in corneal stromal tissue engineering...
  7. ncbi A gelatin-g-poly(N-isopropylacrylamide) biodegradable in situ gelling delivery system for the intracameral administration of pilocarpine
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    Biomaterials 33:2372-87. 2012
    ..e., miosis and IOP lowering effect and preservation of corneal endothelial cell density)...
  8. ncbi Biocompatibility of chemically cross-linked gelatin hydrogels for ophthalmic use
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, 33302, Taoyuan, Taiwan, Republic of China
    J Mater Sci Mater Med 21:1899-911. 2010
    ..In comparison to GTA treatment, the EDC cross-linking is more suitable for preparation of chemically modified gelatin hydrogels for ophthalmic use...
  9. ncbi Ocular biocompatibility of carbodiimide cross-linked hyaluronic acid hydrogels for cell sheet delivery carriers
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    J Biomater Sci Polym Ed 21:359-76. 2010
    ..It is concluded that the cross-linking agent type gives influence on ocular biocompatibility of cell carriers and the EDC-HA hydrogel is an ideal candidate for use as an implantable material in cell sheet delivery applications...
  10. ncbi Low Bloom strength gelatin as a carrier for potential use in retinal sheet encapsulation and transplantation
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan 33302, Republic of China
    Biomacromolecules 10:310-9. 2009
    ....
  11. ncbi Carbodiimide cross-linked amniotic membranes for cultivation of limbal epithelial cells
    David Hui Kang Ma
    Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan, ROC
    Biomaterials 31:6647-58. 2010
    ..It is concluded that the AM cross-linked with 0.05 mmol EDC/mg AM may be a potential biomaterial for regenerative medicine...
  12. ncbi Up-regulation of heat shock protein 70-1 (Hsp70-1) in human limbo-corneal epithelial cells cultivated on amniotic membrane: A proteomic study
    David Hui Kang Ma
    Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Cell Physiol 227:2030-9. 2012
    ..Thus, deltaNp63α-associated Hsp70-1 over-expression may promote HLE progenitor cell survival on IAM, possibly through the cytoprotective and anti-apoptotic effect of Hsp70-1...
  13. ncbi Tissue-engineered human corneal endothelial cell sheet transplantation in a rabbit model using functional biomaterials
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan, ROC
    Transplantation 84:1222-32. 2007
    ..This study was performed to investigate whether transplantation of bioengineered human corneal endothelial cell (HCEC) sheet grafts into corneas denuded of endothelium could restore corneal function and clarity in a rabbit model...
  14. ncbi Persistence of transplanted oral mucosal epithelial cells in human cornea
    Hung Chi Jesse Chen
    Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Invest Ophthalmol Vis Sci 50:4660-8. 2009
    ..To determine the expression of differentiation and progenitor cell markers in corneal tissues that previously underwent autologous cultivated oral mucosal epithelial transplantation (COMET)...
  15. ncbi Cyclosporine a eye drop-induced elongated eyelashes: a case report
    Hsiao Lei Lei
    Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC
    Case Report Ophthalmol 2:398-400. 2011
    ..Here, we report a specific side effect of CsA, namely eye drop-induced eyelash elongation in a patient with refractory giant papillary conjunctivitis...
  16. ncbi Matrix revolution: molecular mechanism for inflammatory corneal neovascularization and restoration of corneal avascularity by epithelial stem cell transplantation
    David Hui Kang Ma
    Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Ocul Surf 7:128-44. 2009
    ..Taken together, the merits of enhanced anti-angiogenic activity and the preservation of corneal epithelial stem cells encourage further application of this tissue engineering technique for ocular surface reconstruction...
  17. ncbi In vitro response of retinal pigment epithelial cells exposed to chitosan materials prepared with different cross-linkers
    Jui Yang Lai
    Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, 33302, Taiwan
    Int J Mol Sci 11:5256-72. 2010
    ..In terms of material safety, the GP cross-linked chitosan may be compatible with human RPE cells and may have a potential application as delivery carriers in the treatment of posterior segment diseases...