Cheng Hsun Chiu

Summary

Affiliation: Chang Gung Memorial Hospital
Country: Taiwan

Publications

  1. pmc Differential genomic variation between short- and long-term bacterial evolution revealed by ultradeep sequencing
    Ye Feng
    Genomics Research Center, Harbin Medical University, People s Republic of China
    Genome Biol Evol 5:572-7. 2013
  2. pmc Clonal dissemination of the multi-drug resistant Salmonella enterica serovar Braenderup, but not the serovar Bareilly, of prevalent serogroup C1 Salmonella from Taiwan
    Chien Shun Chiou
    The Central Region Laboratory, Center of Research and Diagnostics, Centers for Disease Control, No 30, Wenxin S 3rd Rd, Nantun Dist, Taichung, 40856, Taiwan
    BMC Microbiol 9:264. 2009
  3. pmc Characterization of 13 multi-drug resistant Salmonella serovars from different broiler chickens associated with those of human isolates
    Lan Ho Chiu
    Department of Microbiology and Immunology, National Chiayi University, No 300, University Rd, Chiayi, 60004, Taiwan
    BMC Microbiol 10:86. 2010
  4. pmc Survey of childhood empyema in Asia: implications for detecting the unmeasured burden of culture-negative bacterial disease
    Batmunkh Nyambat
    Division of Translational Research, International Vaccine Institute, Seoul, South Korea
    BMC Infect Dis 8:90. 2008
  5. pmc Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14
    Feng Ding
    The CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China
    BMC Genomics 10:158. 2009
  6. pmc Salmonella enterica serotype Choleraesuis: epidemiology, pathogenesis, clinical disease, and treatment
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Clin Microbiol Rev 17:311-22. 2004
  7. pmc Prevalence and antimicrobial susceptibility of serogroup D nontyphoidal Salmonella in a university hospital in Taiwan
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan 333, Taiwan
    J Clin Microbiol 42:415-7. 2004
  8. pmc Fluoroquinolone resistance in Salmonella enterica serotype Choleraesuis, Taiwan, 2000-2003
    Cheng Hsun Chiu
    Chang Gung Children s Hospital, Taoyuan, Taiwan
    Emerg Infect Dis 10:1674-6. 2004
  9. pmc Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, 5 Fu Hsin Street, Kweishan 333, Taoyuan, Taiwan
    Antimicrob Agents Chemother 51:3404-6. 2007
  10. pmc The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital Taoyuan, Taiwan
    Nucleic Acids Res 33:1690-8. 2005

Detail Information

Publications135 found, 100 shown here

  1. pmc Differential genomic variation between short- and long-term bacterial evolution revealed by ultradeep sequencing
    Ye Feng
    Genomics Research Center, Harbin Medical University, People s Republic of China
    Genome Biol Evol 5:572-7. 2013
    ..These findings suggest that the genomic differences between closely related bacterial strains have already undergone selection and are therefore not representative of spontaneous mutation...
  2. pmc Clonal dissemination of the multi-drug resistant Salmonella enterica serovar Braenderup, but not the serovar Bareilly, of prevalent serogroup C1 Salmonella from Taiwan
    Chien Shun Chiou
    The Central Region Laboratory, Center of Research and Diagnostics, Centers for Disease Control, No 30, Wenxin S 3rd Rd, Nantun Dist, Taichung, 40856, Taiwan
    BMC Microbiol 9:264. 2009
    ..Bareilly) and Braenderup (S. Braenderup) were compared, and multi-drug resistance (MDR) plasmids were characterized...
  3. pmc Characterization of 13 multi-drug resistant Salmonella serovars from different broiler chickens associated with those of human isolates
    Lan Ho Chiu
    Department of Microbiology and Immunology, National Chiayi University, No 300, University Rd, Chiayi, 60004, Taiwan
    BMC Microbiol 10:86. 2010
    ..To understand the possible serovar and H antigens for transmission between chicken and human, serovars and their H antigens of 164 chicken and 5314 human isolates were compared...
  4. pmc Survey of childhood empyema in Asia: implications for detecting the unmeasured burden of culture-negative bacterial disease
    Batmunkh Nyambat
    Division of Translational Research, International Vaccine Institute, Seoul, South Korea
    BMC Infect Dis 8:90. 2008
    ..Parapneumonic empyema continues to be a disease of significant morbidity and mortality among children despite recent advances in medical management. To date, only a limited number of studies have assessed the burden of empyema in Asia...
  5. pmc Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14
    Feng Ding
    The CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China
    BMC Genomics 10:158. 2009
    ..Multiple serotype 14 clinical isolates were also genotyped by multilocus sequence typing (MLST)...
  6. pmc Salmonella enterica serotype Choleraesuis: epidemiology, pathogenesis, clinical disease, and treatment
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Clin Microbiol Rev 17:311-22. 2004
    ..The availability, in the near future, of the genome sequence of serotype Cholearesuis will facilitate the development of effective vaccines as well as the discovery of new targets for novel antimicrobial agents...
  7. pmc Prevalence and antimicrobial susceptibility of serogroup D nontyphoidal Salmonella in a university hospital in Taiwan
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan 333, Taiwan
    J Clin Microbiol 42:415-7. 2004
    ..Furthermore, the first identification of ciprofloxacin and ceftriaxone resistance in serogroup D Salmonella in our hospital is also than they did to other antimicrobial agents cause for concern...
  8. pmc Fluoroquinolone resistance in Salmonella enterica serotype Choleraesuis, Taiwan, 2000-2003
    Cheng Hsun Chiu
    Chang Gung Children s Hospital, Taoyuan, Taiwan
    Emerg Infect Dis 10:1674-6. 2004
    ..Surveillance in Taiwan showed that fluoroquinolone resistance in S. Choleraesuis markedly increased from 2000 to 2003, reaching approximately 70% in 2003...
  9. pmc Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, 5 Fu Hsin Street, Kweishan 333, Taoyuan, Taiwan
    Antimicrob Agents Chemother 51:3404-6. 2007
    ..Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance...
  10. pmc The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital Taoyuan, Taiwan
    Nucleic Acids Res 33:1690-8. 2005
    ..Our findings suggest that the formation of pseudogenes may provide a simple evolutionary pathway that complements gene acquisition to enhance virulence and antimicrobial resistance in S. Choleraesuis...
  11. pmc Liver abscess caused by Klebsiella pneumoniae in siblings
    C H Chiu
    Divisions of Pediatric Infectious Diseases, Department of Medicine, Chang Gung Children s Hospital, 5 Fu Hsin Street, Kweishan 333, Taoyuan, Taiwan
    J Clin Microbiol 39:2351-3. 2001
    ..pneumoniae isolates from two siblings with liver abscess, their family members, and the environment suggest a possibility of cross infection of liver abscess by the fecal-oral route within diabetic patients...
  12. ncbi request reprint The emergence in Taiwan of fluoroquinolone resistance in Salmonella enterica serotype choleraesuis
    Cheng Hsun Chiu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    N Engl J Med 346:413-9. 2002
    ..Because fluoroquinolones are the drug of choice for the treatment of severe salmonella infections, the emergence and dissemination of fluoroquinolone-resistant S. enterica serotype choleraesuis have clinical consequences...
  13. ncbi request reprint Salmonella enterica serotype Choleraesuis infections in pediatric patients
    Cheng Hsun Chiu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University, Taoyuan, Taiwan
    Pediatrics 117:e1193-6. 2006
    ..The objective of this study was to delineate the clinical and microbiologic features of pediatric patients with Salmonella Choleraesuis infections...
  14. ncbi request reprint Protection of neonatal mice from lethal enterovirus 71 infection by maternal immunization with attenuated Salmonella enterica serovar Typhimurium expressing VP1 of enterovirus 71
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Kweishan, Taoyuan 333, Taiwan
    Microbes Infect 8:1671-8. 2006
    ..Our data indicated that Salmonella-based VP1 subunit vaccines are a promising vaccine strategy in the prevention of EV71 infection...
  15. doi request reprint The impact of constipation on growth in children
    Hsun Chin Chao
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Kweishan, Taoyuan 33305, Taiwan
    Pediatr Res 64:308-11. 2008
    ..We conclude that chronic constipation may retard growth status in children, and a long-term medication for constipation in children appears beneficial to their growth status...
  16. pmc Detection of multidrug-resistant Salmonella enterica serovar typhimurium phage types DT102, DT104, and U302 by multiplex PCR
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, and Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Clin Microbiol 44:2354-8. 2006
    ..Nevertheless, the multiplex PCR devised in the present study appears to be efficient and useful in the rapid identification of ACSSuT-type serovar Typhimurium with SGI1, irrespective of their phage types...
  17. ncbi request reprint Neonatal enterovirus infections: emphasis on risk factors of severe and fatal infections
    Tzou Yien Lin
    Division of Pediatric Infecti ious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    Pediatr Infect Dis J 22:889-94. 2003
    ..Neonatal enterovirus infections have diverse manifestations, from asymptomatic to fatal. An understanding of the risk factors associated with severe cases might help to reduce enterovirus-related morbidity and mortality...
  18. ncbi request reprint Molecular epidemiology of Salmonella enterica serovar Enteritidis isolated in Taiwan
    Lin Hui Su
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Kweishan, 333, Taoyuan, Taiwan
    Microbiol Immunol 46:833-40. 2002
    ..Between the two, the latter, though less discriminatory than PFGE, seems the method of choice, since it is simpler, less time-consuming and above all easy to perform...
  19. pmc In vivo acquisition of ceftriaxone resistance in Salmonella enterica serotype anatum
    Lin Hui Su
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Antimicrob Agents Chemother 47:563-7. 2003
    ..The emergence of resistance to ceftriaxone in S. enterica serotype Anatum was due to the in vivo acquisition of a plasmid containing the bla(CTX-M-3) gene and was the cause for treatment failure in this patient...
  20. doi request reprint Wide spread of Tn2006 in an AbaR4-type resistance island among carbapenem-resistant Acinetobacter baumannii clinical isolates in Taiwan
    Hao Yuan Lee
    Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Int J Antimicrob Agents 40:163-7. 2012
    ..009 and 0.027, respectively). Tn2006 is currently the most common imipenem resistance determinant, which showed a higher ability to spread among A. baumannii and was associated with a higher mortality in IRAB-infected patients...
  21. doi request reprint Functional and molecular characterization of pSE34 encoding a type IV secretion system in Salmonella enterica serotype Enteritidis phage type 34
    Chyi Liang Chen
    Molecular Infectious Diseases Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    FEMS Immunol Med Microbiol 57:274-83. 2009
    ..The presence of conjugative pSE34 in PT4 caused the conversion of phage type from PT4 to PT34, suggesting that the emergence of PT34 was a result of the introduction of the conjugative pSE34 into its common progenitor PT4...
  22. ncbi request reprint Clinical features and genotyping analysis of community-acquired methicillin-resistant Staphylococcus aureus infections in Taiwanese children
    Chih Jung Chen
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, 5 Fu Shin Street, 333, Taoyuan, Taiwan
    Pediatr Infect Dis J 24:40-5. 2005
    ..To evaluate the clinical features and genotyping analysis of CA-MRSA in children in Taiwan, we conducted this study...
  23. ncbi request reprint Distribution of a transposon-like element carrying bla(CMY-2) among Salmonella and other Enterobacteriaceae
    Lin Hui Su
    Department of Clinical Pathology, Chang Gung Memorial Hospital, 5 Fu Hsin Street, Kweishan, Taoyuan 333, Taiwan
    J Antimicrob Chemother 57:424-9. 2006
    ..The dissemination of cephamycin resistance in Enterobacteriaceae and its correlation with a transposon-like DNA element consisting of a specific tnpA-bla(CMY-2)-blc-sugE structure were investigated...
  24. ncbi request reprint Multidrug-resistant non-typhoid Salmonella infections in a medical center
    Chien Yu Lee
    Department of Pediatrics, Provincial Tao Yuan Hospital, Taiwan, ROC
    J Microbiol Immunol Infect 35:78-84. 2002
    ..choleraesuis found in this study indicate the importance of judicious use of antimicrobial agents in both humans and animals to reduce the selection and spread of resistant strains...
  25. ncbi request reprint Dissemination of extended-spectrum beta-lactamase-producing Enterobacteriaceae in intensive care units of a medical center in Taiwan
    Tsu Lan Wu
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Microb Drug Resist 12:203-9. 2006
    ....
  26. ncbi request reprint Probiotics have clinical, microbiologic, and immunologic efficacy in acute infectious diarrhea
    Chien Chang Chen
    Division of Gastroenterology, Department of Pediatrics, Chang Gung Children s Hospital, Taiwan
    Pediatr Infect Dis J 29:135-8. 2010
    ..Acute infectious diarrhea is a major cause of childhood morbidity and economic burden for families. We evaluate the clinical, microbiologic, and immunologic effects of probiotics in acute infectious diarrhea...
  27. ncbi request reprint Safety and immunogenicity of a diphtheria, tetanus, and acellular pertussis-inactivated poliovirus vaccine/Haemophilus influenzae type B combination vaccine administered to Taiwanese infants at 2, 4, and 6 months of age
    Tzou Yien Lin
    Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Taipei
    Chang Gung Med J 26:315-22. 2003
    ....
  28. pmc Dissemination of extended-spectrum beta-lactamase-producing Enterobacteriaceae in pediatric intensive care units
    Tsu Lan Wu
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Clin Microbiol 41:4836-8. 2003
    ....
  29. pmc Molecular epidemiology and clinical manifestations of viral gastroenteritis in hospitalized pediatric patients in Northern Taiwan
    Shih Yen Chen
    Division of Pediatric Gastroenterology, Chang Gung University College of Medicine, Kweishan 333, Taoyuan, Taiwan
    J Clin Microbiol 45:2054-7. 2007
    ..Higher disease severity was found for AGE caused by multiple viruses and by rotavirus alone. The majority of rotaviruses isolated from 2004 to 2006 belonged to genotypes G1 (20.4%), G2 (16.5%), G3 (27.2%), and G9 (21.4%)...
  30. doi request reprint Mechanisms of resistance to ciprofloxacin, ampicillin/sulbactam and imipenem in Acinetobacter baumannii clinical isolates in Taiwan
    Cheng Hsun Chiu
    Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Int J Antimicrob Agents 35:382-6. 2010
    ..The major metallo-beta-lactamase contributing to imipenem resistance in A. baumannii in Taiwan was bla(IMP-1), which was carried by the class 1 integron. The class 1 integron was associated with the MDR phenotype in A. baumannii...
  31. ncbi request reprint Increasing ceftriaxone resistance in Salmonella isolates from a university hospital in Taiwan
    Lin Hui Su
    Department of Clinical Pathology, Lin Kou Medical Center, Chang Gung Memorial Hospital, 5 Fu Hsin Street, Kweishan 333, Taoyuan, Taiwan
    J Antimicrob Chemother 55:846-52. 2005
    ..Salmonella infection is a distressing health problem worldwide. This study reports the changing epidemiology of Salmonella infections in Taiwan during 1999-2003, with emphasis on increasing ceftriaxone resistance...
  32. pmc Extended epidemic of nosocomial urinary tract infections caused by Serratia marcescens
    Lin Hui Su
    Department of Clinical Pathology, Lin Kou Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Clin Microbiol 41:4726-32. 2003
    ..Both a cautious review of laboratory and infection control data and an efficient genotyping system are necessary to identify such a cryptic epidemic and further contribute to the quality of patient care...
  33. pmc Development of a multiplex PCR and SHV melting-curve mutation detection system for detection of some SHV and CTX-M beta-lactamases of Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae in Taiwan
    Ju Hsin Chia
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Clin Microbiol 43:4486-91. 2005
    ..coli, K. pneumoniae, and Enterobacter cloacae in Taiwan. Moreover, the design of the system can be easily adapted for similar purposes in areas where different ESBLs are prevalent...
  34. ncbi request reprint The impact of the heptavalent pneumococcal conjugate vaccine on risk factors for Streptococcus pneumoniae carriage in children
    Yu Chia Hsieh
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan
    Pediatr Infect Dis J 31:e163-8. 2012
    ..The aim of the study was to investigate whether the 7-valent pneumococcal conjugate vaccine (PCV7) alters common risk factors of nasopharyngeal carriage by Streptococcus pneumoniae in children...
  35. doi request reprint Antigenemia and cytokine expression in rotavirus gastroenteritis in children
    Tsung Han Yu
    Divisions of Pediatric Gastroenterology, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Microbiol Immunol Infect 45:265-70. 2012
    ..The aim of this study was to evaluate the association of antigenemia with clinical manifestations and cytokine profiles in children infected by rotavirus...
  36. ncbi request reprint Nontyphoidal Salmonella bacteremia in previously healthy children: analysis of 199 episodes
    Ming Han Tsai
    Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan
    Pediatr Infect Dis J 26:909-13. 2007
    ..Nontyphoidal Salmonella (NTS) bacteremia is not rare in otherwise healthy children in Taiwan. Few studies described the clinical manifestations and outcomes of NTS bacteremia in previously healthy children...
  37. doi request reprint Comparison of clinical features between coxsackievirus A2 and enterovirus 71 during the enterovirus outbreak in Taiwan, 2008: a children's hospital experience
    Shih Perng Chen
    Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Medical Center, Taoyuan, Taiwan
    J Microbiol Immunol Infect 43:99-104. 2010
    ..In this study, we compared Cox A2 with enterovirus 71 (EV71) in terms of clinical manifestation and epidemiology during the 2008 enterovirus outbreak in Taiwan...
  38. ncbi request reprint CMY-2 beta-lactamase-carrying community-acquired urinary tract Escherichia coli: genetic correlation with Salmonella enterica serotypes Choleraesuis and Typhimurium
    Tsu Lan Wu
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Int J Antimicrob Agents 29:410-6. 2007
    ..Awareness of this mobile resistance element is required to prevent introduction into hospitals and to reduce the spread of this emerging resistance within the community...
  39. ncbi request reprint Hemolytic uremic syndrome associated with pneumococcal pneumonia in Taiwan
    Yu Hsuan Huang
    Division of Pediatric Pulmonology, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University, College of Medicine, 5, Fu Hsin Street, Taoyuan, Taiwan
    Eur J Pediatr 165:332-5. 2006
    ..The long-term prognosis for recovery of renal function appears to be good in these patients in northern Taiwan...
  40. doi request reprint Clinical manifestations, antibiotic susceptibility and molecular analysis of Mycobacterium kansasii isolates from a university hospital in Taiwan
    Ting Shu Wu
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Gueishan Shiang 33305, Taoyuan, Taiwan
    J Antimicrob Chemother 64:511-4. 2009
    ..The purpose of this study was to establish a relationship between the clinical treatment outcomes of M. kansasii infections and bacterial drug susceptibility, and their clonality...
  41. doi request reprint Renal abscess in children: a 10-year clinical and radiologic experience in a tertiary medical center
    Chi Hui Cheng
    Division of Pediatric Nephrology, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Taiwan
    Pediatr Infect Dis J 27:1025-7. 2008
    ..Experiences gained from this 10-year study on patients with CT-proved diagnosis include the varied clinical presentations and use of sonographic-marked nephromegaly and focal mass as indications for further CT diagnosis...
  42. doi request reprint Epidemiology of acute otitis media among young children: a multiple database study in Taiwan
    Pei Ju Ting
    Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan
    J Microbiol Immunol Infect 45:453-8. 2012
    ..The purpose of this study was to evaluate the epidemiology of AOM among young children in Taiwan, including the age incidence and seasonality by combining multiple databases...
  43. doi request reprint Recognition of mechanisms involved in bile resistance important to halting antimicrobial resistance in nontyphoidal Salmonella
    Ming Han Tsai
    Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan
    Int J Antimicrob Agents 40:151-7. 2012
    ..Addition of an efflux pump inhibitor to fluoroquinolones may be an effective strategy to deal with the increasing resistance in NTS...
  44. doi request reprint Imipenem heteroresistance induced by imipenem in multidrug-resistant Acinetobacter baumannii: mechanism and clinical implications
    Hao Yuan Lee
    Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Int J Antimicrob Agents 37:302-8. 2011
    ..Physicians should weigh the benefits and risks of each carbapenem-based treatment in managing carbapenem-susceptible MDR-AB infection...
  45. doi request reprint Sequence types and antimicrobial susceptibility of invasive streptococcus pneumoniae isolates from a region with high antibiotic selective pressure and suboptimal vaccine coverage
    Rajendra Prasad Janapatla
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Pediatr Infect Dis J 29:467-9. 2010
    ..Antimicrobial nonsusceptibility was common in the predominant STs of serotypes 14, 19A, 19F, and 23F...
  46. pmc Characterization of a laboratory-derived, high-level ampicillin-resistant Salmonella enterica serovar Typhimurium strain that caused meningitis in an infant
    Cheng Hsun Chiu
    Department of Pediatrics, Chang Gung Children s Hospital, Kweishan 333, Taoyuan, Taiwan
    Antimicrob Agents Chemother 46:1604-6. 2002
    ..This 3.2-kb plasmid was further characterized to be a nonconjugative pGEM series cloning vector containing a foreign insert. The strain was likely laboratory derived and contaminated the environment before it caused the infection...
  47. ncbi request reprint Clinical observation of meningitis caused by penicillin-susceptible and -non-susceptible Streptococcus pneumoniae in Taiwanese children
    Shih Hsiang Chen
    Division of Pediatrics, Chang Gung Children s Hospital, Taipei, Taiwan, Republic of China
    Ann Trop Paediatr 26:181-5. 2006
    ..To compare differences between clinical features and outcome in bacterial meningitis caused by penicillin-susceptible Streptococcus pneumoniae (PSSP) with that caused by penicillin-non-susceptible Streptococcus pneumoniae (PNSP)...
  48. doi request reprint Genetic characterization of enterovirus 71 isolated from patients with severe disease by comparative analysis of complete genomes
    Shih Cheng Chang
    Research Center for Emerging Viral Infections, Chang Gung University, Taoyuan, Taiwan
    J Med Virol 84:931-9. 2012
    ..Further studies of EV71 pathogenesis should examine the significance of genomic diversity and the effects of multiple mutations in a viral population...
  49. ncbi request reprint Experience with linezolid therapy in children with osteoarticular infections
    Chih Jung Chen
    Division of Pediatric Infectious Diseases, Department of Pediatrics Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Pediatr Infect Dis J 26:985-8. 2007
    ..The clinical efficacy of this drug has not been previously evaluated for Gram-positive osteoarticular infections in children...
  50. ncbi request reprint Clinical features and molecular characteristics of invasive community-acquired methicillin-resistant Staphylococcus aureus infections in Taiwanese children
    Chih Jung Chen
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan 333, Taiwan
    Diagn Microbiol Infect Dis 59:287-93. 2007
    ..Surgical interventions were often required, and a prolonged course of antibiotic therapy was needed. A multiresistant CA-MRSA clone characterized as ST59 was identified from these children in Taiwan...
  51. doi request reprint Immunogenicity and safety of 10-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) co-administered with routine childhood vaccines in Taiwan
    Tzou Yien Lin
    Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taiwan
    J Formos Med Assoc 111:495-503. 2012
    ..The immunogenicity and safety of the 10-valent pneumococcal nontypeable Haemophilus influenzae (H. Influenzae) protein D conjugate vaccine (PHiD-CV), co-administered with routine childhood vaccines, were assessed in Taiwanese infants...
  52. ncbi request reprint Salmonella enterica serotype Choleraesuis infection in a medical center in northern Taiwan
    Shun Chiu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, 5 Fu Hsin Street, Kweishan, Taoyuan, Taiwan 333, ROC
    J Microbiol Immunol Infect 37:99-102. 2004
    ..In view of the emergence of fluoroquinolone resistance, the third-generation cephalosporins appear to be the best choice for treatment of invasive infections caused by this organism...
  53. ncbi request reprint Mycobacterium marinum infection in Taiwan
    Ting Shu Wu
    Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC
    J Microbiol Immunol Infect 35:42-6. 2002
    ..Poor healing of wounds after exposure to aquatic animals appears to be the most important clinical clue indicating the need for culture and inclusion of M. marinum infection in the differential diagnosis...
  54. ncbi request reprint Acute hematogenous osteomyelitis and septic arthritis in children
    Hui Chin Kao
    Department of Pediatrics, Li Shin Hospital, Taiwan, ROC
    J Microbiol Immunol Infect 36:260-5. 2003
    ..aureus as a cause of bone and joint infections has been increasing. Serum bactericidal titer is valuable for the management of patients receiving sequential therapy for acute hematogenous osteomyelitis and septic arthritis...
  55. doi request reprint Host and microbiologic factors associated with mortality in Taiwanese children with invasive pneumococcal diseases, 2001 to 2006
    Chih Jung Chen
    Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Diagn Microbiol Infect Dis 63:194-200. 2009
    ..1; 95% CI, 1.4-47.3), which are the independent predictors for fatality. This finding highlighted the importance of immunization of disadvantaged children, targeting drug-resistant pneumococci...
  56. doi request reprint Antimicrobial susceptibility of Streptococcus pneumoniae at a university hospital in Taiwan, 2000-07: impact of modified non-meningeal penicillin breakpoints in CLSI M100-S18
    Lin Hui Su
    Department of Laboratory Medicine, Chang Gung Memorial Hospital, 5 Fu Hsin Street, Kweishan, Taoyuan 333, Taiwan
    J Antimicrob Chemother 64:336-42. 2009
    ..In 2008, a new set of penicillin breakpoints was published in the CLSI revised guideline, M100-S18, to define the susceptibility of non-meningeal isolates of Streptococcus pneumoniae. The impact of the change is studied and discussed...
  57. pmc Group B streptococcal disease in nonpregnant patients: emergence of highly resistant strains of serotype Ib in Taiwan in 2006 to 2008
    Ying Hsiang Wang
    Department of Pediatrics, Chang Gung Memorial Hospital, Chiayi, Taiwan
    J Clin Microbiol 48:2571-4. 2010
    ..Serotype Ib isolates (24.6%) were the second most prevalent serotype, next to serotype V (29.4%), and showed the highest resistance rates to erythromycin (91.0%) and clindamycin (82.1%)...
  58. doi request reprint Nasopharyngeal carriage of Streptococcus pneumoniae in Taiwan before and after the introduction of a conjugate vaccine
    Chen Yen Kuo
    Department of Pediatrics, Chang Gung Children s Hospital, College of Medicine, Chang Gung University, 5 Fu Hsin Street, Kwei Shan Hsiang, Taoyuan, Taiwan
    Vaccine 29:5171-7. 2011
    ..To evaluate the effect of the vaccination, we conducted an active, prospective, large-scale, long-term, and multicenter study to assess the prevalence of nasopharyngeal Streptococcus pneumoniae carriage in Taiwanese children...
  59. ncbi request reprint Clinical responses of patients with Kawasaki disease to different brands of intravenous immunoglobulin
    Ming Han Tsai
    Division of Pediatric Infectious Diseases, Division of Taipei Pediatrics, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Pediatr 148:38-43. 2006
    ..To determine whether different brands of intravenous immunoglobulin (IVIG) administered to children with Kawasaki disease (KD) result in different outcomes...
  60. pmc Outbreak of dysentery associated with ceftriaxone-resistant Shigella sonnei: First report of plasmid-mediated CMY-2-type AmpC beta-lactamase resistance in S. sonnei
    I Fei Huang
    Department of Pediatrics, Veterans General Hospital Kaohsiung, 386, Ta Chung 1st Road, Kaohsiung, Taiwan
    J Clin Microbiol 43:2608-12. 2005
    ..This is the first report of plasmid-mediated CMY-2-type AmpC beta-lactamase in S. sonnei. Ampicillin-resistant isolates can develop during the course of antibiotic treatment...
  61. ncbi request reprint Prognostic implications of myoclonic jerk in children with enterovirus infection
    Hsiao Kuo Lu
    Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan, ROC
    J Microbiol Immunol Infect 37:82-7. 2004
    ..95 and 0.99, respectively. This study demonstrated that myoclonic jerk and EV71 infection are both independently associated with more severe disease and higher incidence of neurologic sequelae...
  62. ncbi request reprint Invasion of murine respiratory tract epithelial cells by Chryseobacterium meningosepticum and identification of genes present specifically in an invasive strain
    Pen Yi Lin
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    New Microbiol 29:55-62. 2006
    ..In most cases, the identities between the references and the amino acid sequences deduced were low, suggesting that the functions of these sequences remain unknown...
  63. doi request reprint Complete nucleotide sequence of a virulence plasmid of Salmonella enterica serovar Dublin and its phylogenetic relationship to the virulence plasmids of serovars Choleraesuis, Enteritidis and Typhimurium
    Seau Feng Hong
    Department of Microbiology and Immunology, Chang Gung University College of Medicine, Taoyuan, Taiwan
    FEMS Microbiol Lett 282:39-43. 2008
    ....
  64. doi request reprint Etiology of community-acquired pneumonia in hospitalized children in northern Taiwan
    Chih Jung Chen
    Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, Taiwan
    Pediatr Infect Dis J 31:e196-201. 2012
    ..There has been no comprehensive study of the etiology of childhood community-acquired pneumonia (CAP), either in the pre- or postpneumococcal conjugate vaccine era, in Taiwan...
  65. doi request reprint Prolonged fecal shedding of CTX-M-15-producing Escherichia coli and recurrent sepsis in a patient after cord blood stem-cell transplantation
    Kuan Ying Huang
    Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang GongChildren s Hospital, Taiwan
    Scand J Infect Dis 41:224-7. 2009
    ..The bla(CTX-M-15) is carried by a large plasmid of approximately 130 kb in size. The prolonged shedding of the highly resistant E. coli posed a great challenge to infection control and public health...
  66. doi request reprint Change in the molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream infections in Taiwan
    Chih Jung Chen
    Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, 333, Taoyuan, Taiwan
    Diagn Microbiol Infect Dis 65:199-201. 2009
    ..Multiresistance might be one of the characteristics that could have contributed to its quick adaptation to hospital environments...
  67. ncbi request reprint Translocation of coagulase-negative bacterial staphylococci in rats following intestinal ischemia-reperfusion injury
    Chih Cheng Luo
    Departments of Pediatric Surgery and Pediatrics, Chang Gung Children s Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan
    Biol Neonate 85:151-4. 2004
    ..Intact mucosa integrity readily prevented bacterial translocation; however, bacterial translocation could occur in rats following mild IRI in the presence of a higher number of CoNS in the gut...
  68. ncbi request reprint One-year post-primary antibody persistence and booster immune response to a fully liquid five-component acellular pertussis, diphtheria, tetanus, inactivated poliomyelitis, Haemophilus influenzae type b conjugate vaccine
    Tzou Yien Lin
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University Medicine, Taoyuan, Taipei, Taiwan
    Int J Infect Dis 11:488-95. 2007
    ....
  69. ncbi request reprint Molecular epidemiology and antimicrobial susceptibility of Salmonella enterica serotype Stanley isolates in Taiwan
    Kuan Ying Huang
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Microbiol Immunol Infect 40:411-8. 2007
    ..The present study was conducted to gain further understanding of the epidemiology and antimicrobial suseptibility of S. Stanley...
  70. ncbi request reprint Seroprevalence of human papillomavirus types 16 and 18 in the general population in Taiwan: implication for optimal age of human papillomavirus vaccination
    Chih Jung Chen
    Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu Shin Street, Kweishan 333, Taoyuan, Taiwan
    J Clin Virol 38:126-30. 2007
    ..The optimal age for administration of recently approved prophylactic human papillomavirus (HPV) vaccines remains undetermined...
  71. doi request reprint Pseudogene recoding revealed from proteomic analysis of salmonella serovars
    Ye Feng
    Genomics Research Center, Harbin Medical University, Harbin, PR China
    J Proteome Res 11:1715-9. 2012
    ..We believe that the phenomena of recoding are not rare in bacteria. More studies are required for a better understanding of bacterial translation and the implication of pseudogene recoding in Salmonella serovars...
  72. doi request reprint Enterovirus 71 in Taiwan, 2004-2006: epidemiological and virological features
    Kuan Ying Huang
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Scand J Infect Dis 40:571-4. 2008
    ..No obvious phylogenetically distinct clones or clusters were found related to varying degrees of disease severity or clinical manifestations...
  73. ncbi request reprint Genotyping and antimicrobial susceptibility of Salmonella enterica serotype Panama isolated in Taiwan
    Hao Yuan Lee
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Microbiol Immunol Infect 41:507-12. 2008
    ..The present study was undertaken to gain more understanding of the molecular epidemiology and antimicrobial resistance of Salmonella Panama...
  74. doi request reprint Clinical features of echovirus 6 and 9 infections in children
    Hao Yuan Lee
    Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Clin Virol 49:175-9. 2010
    ..Clinical features of echovirus 6 and 9 infections in children have not been comprehensively evaluated, particularly for sporadic cases...
  75. doi request reprint Cutoff volume of dietary fiber to ameliorate constipation in children
    Hsun Chin Chao
    Division of Gastroenterology, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Pediatr 153:45-9. 2008
    ..To evaluate the proper ingested volume of dietary fiber for relieving constipation in children...
  76. ncbi request reprint The 1998 enterovirus 71 outbreak in Taiwan: pathogenesis and management
    Tzou Yien Lin
    Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    Clin Infect Dis 34:S52-7. 2002
    ..After poliovirus is eradicated, EV71 will become the most important enterovirus that affects children, and development of a vaccine may be the only effective measure against it...
  77. doi request reprint Waning population immunity to measles in Taiwan
    Chih Jung Chen
    Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, 333 Taoyuan, Taiwan
    Vaccine 30:6721-7. 2012
    ..The waning vaccine-induced immunity may have impact on the control of measles in the future, especially when the vaccinated population becomes older...
  78. doi request reprint Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985-2010
    Wen I Lee
    Primary Immunodeficiency Care and Research PICAR Institute, Chang Gung University College of Medicine and Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Immunobiology 216:1286-94. 2011
    ..Awareness of under-diagnosis among physicians rather than pediatricians is vital for timely diagnosis and consequently adequate treatment...
  79. doi request reprint Seroprevalence of SARS Coronavirus Among Residents Near a Hospital with a Nosocomial Outbreak
    Ming Han Tsai
    Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, and Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taiwan
    J Formos Med Assoc 107:885-91. 2008
    ....
  80. doi request reprint Antibiotic resistance patterns of community-acquired urinary tract infections in children with vesicoureteral reflux receiving prophylactic antibiotic therapy
    Chi Hui Cheng
    Department of Pediatrics, Chang Gung Children s Hospital, and Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Pediatrics 122:1212-7. 2008
    ..The goal was to examine bacterial antimicrobial resistance of recurrent urinary tract infections in children receiving antibiotic prophylaxis because of primary vesicoureteral reflux...
  81. ncbi request reprint Antimicrobial susceptibility of Shigella isolates in eight Asian countries, 2001-2004
    Chen Yen Kuo
    Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Microbiol Immunol Infect 41:107-11. 2008
    ..Because of increasing trends towards drug resistance, this study was undertaken to monitor local resistance patterns of Shigella isolates from 8 Asian countries...
  82. pmc High rate of reduced susceptibility to ciprofloxacin and ceftriaxone among nontyphoid Salmonella clinical isolates in Asia
    Hao Yuan Lee
    Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Antimicrob Agents Chemother 53:2696-9. 2009
    ..8%) and S. Virchow (75.0%) from all countries. Reduced susceptibility to ceftriaxone (MIC, 2 to 8 microg/ml) remained uncommon in Asia, except in Taiwan (38.0%) or in S. Typhimurium (25.0%) from all countries...
  83. doi request reprint Norovirus infection as a cause of diarrhea-associated benign infantile seizures
    Shih Yen Chen
    Divisions of 1Pediatric Gastroenterology, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Clin Infect Dis 48:849-55. 2009
    ....
  84. pmc Nucleotide and amino acid sequences of oriT-traM-traJ-traY-traA-traL regions and mobilization of virulence plasmids of Salmonella enterica serovars enteritidis, gallinarum-pullorum, and typhimurium
    Chishih Chu
    Department of Microbiology and Immunology, Chang Gung University College of Medicine, Taiwan
    J Bacteriol 184:2857-62. 2002
    ....
  85. ncbi request reprint A multiplex polymerase chain reaction method for rapid identification of Citrobacter freundii and Salmonella species, including Salmonella Typhi
    Chia Ling Lin
    Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Microbiol Immunol Infect 40:222-6. 2007
    ..We devised a polymerase chain reaction (PCR) method that simultaneously uses three pairs of specific primers to detect inv, spv, and via genes of Salmonella...
  86. doi request reprint National survey of invasive pneumococcal diseases in Taiwan under partial PCV7 vaccination in 2007: emergence of serotype 19A with high invasive potential
    Yu Chia Hsieh
    Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan
    Vaccine 27:5513-8. 2009
    ..7% of cases in children aged <2 years. Among patients aged >or=65 years, the 23-valent pneumococcal polysaccharide vaccine covered 70.4% of cases. In the future, a broader pneumococcal vaccine is needed...
  87. doi request reprint Biofilm production, use of intravascular indwelling catheters and inappropriate antimicrobial therapy as predictors of fatality in Chryseobacterium meningosepticum bacteraemia
    Pen Yi Lin
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Int J Antimicrob Agents 36:436-40. 2010
    ..The outcome of patients with biofilm-forming C. meningosepticum infection was adversely affected by the choice of inappropriate antimicrobial therapy and the use of long-term indwelling intravascular catheters...
  88. doi request reprint Clinical and epidemiologic features of Coxsackievirus A6 infection in children in northern Taiwan between 2004 and 2009
    Shih Hsuan Lo
    Department of Pediatrics, Children s Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Microbiol Immunol Infect 44:252-7. 2011
    ..This study is to define clinical manifestations and laboratory findings of Cox A6 infection in children...
  89. pmc Seroprevalence and severity of 2009 pandemic influenza A H1N1 in Taiwan
    Chih Jung Chen
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Taoyuan, Taiwan
    PLoS ONE 6:e24440. 2011
    ..This study is to determine the seroprevalence of the pandemic influenza A H1N1 virus (pH1N1) in Taiwan before and after the 2009 pandemic, and to estimate the relative severity of pH1N1 infections among different age groups...
  90. doi request reprint Implementation and outcomes of a hospital-wide computerised antimicrobial stewardship programme in a large medical centre in Taiwan
    Yuk Ying Chan
    Department of Pharmacy, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Int J Antimicrob Agents 38:486-92. 2011
    ..HCAAS is a sustainable system for providing antibiotic stewardship and exerts a positive impact on the hospital by reducing antimicrobial consumption and expenditure whilst not compromising healthcare quality...
  91. pmc Multidrug resistant Acinetobacter baumannii: risk factors for appearance of imipenem resistant strains on patients formerly with susceptible strains
    Jung Jr Ye
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taoyuan, Taiwan
    PLoS ONE 5:e9947. 2010
    ..The study was designed to identify the risk factors for appearance of IR-MDRAB on patients formerly with imipenem susceptible MDRAB (IS-MDRAB) and the impact on clinical outcomes...
  92. ncbi request reprint Clinical analysis of computed tomography-staged orbital cellulitis in children
    Chen Fang Ho
    Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan
    J Microbiol Immunol Infect 40:518-24. 2007
    ..This study sought to delineate the clinical, bacteriological and radiological findings, management and outcome of orbital cellulitis...
  93. ncbi request reprint A cluster of adenovirus serotype 3 infections in children in northern Taiwan: clinical features and laboratory findings
    Chien Hui Lin
    Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Kweishan, Taoyuan, Taiwan
    J Microbiol Immunol Infect 40:302-9. 2007
    ..To define clinical manifestations and laboratory findings of adenovirus serotype 3 infections in children...
  94. ncbi request reprint 2009 Pandemic influenza H1N1: paediatric perspectives
    Hao Yuan Lee
    Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Ann Acad Med Singapore 39:333-3. 2010
    ..This paper reviews the underlying medical conditions associated with death or complications of pandemic H1N1 infection in children...
  95. ncbi request reprint Fulminant Clostridium septicum infection mimicking appendicitis in a healthy child
    Yi Jung Chang
    Division of Paediatric Critical Care and Emergency Medicine, Department of Paediatics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tauyuan, Taiwan
    Ann Trop Paediatr 27:91-4. 2007
    ..On the day after admission, shock, neutropenia and pneumoperitoneum prompted a laparotomy. Gangrene of the ileum and colon was identified, associated with a fatal Clostridium septicum infection...
  96. ncbi request reprint An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae
    Lin Hui Su
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    FEMS Immunol Med Microbiol 52:155-68. 2008
    ....
  97. doi request reprint Influenza-associated central nervous system dysfunction in Taiwanese children: clinical characteristics and outcomes with and without administration of oseltamivir
    Yhu Chering Huang
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Kweishan, Taoyan, Taiwan
    Pediatr Infect Dis J 28:647-8. 2009
    ..Seventeen children received oseltamivir therapy after admission and no significant difference between administration of oseltamivir and outcome was observed (P = 0.1512 by Fisher exact test)...
  98. doi request reprint Clinical and microbiological analysis of Elizabethkingia meningoseptica bacteremia in adult patients in Taiwan
    Yi Tsung Lin
    Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Scand J Infect Dis 41:628-34. 2009
    ..meningoseptica bacteremia face poor prognoses, with shock and use of inappropriate antibiotics as the main risk factors for mortality. Further clinical study is needed to establish the optimal therapy for E. meningoseptica bacteremia...
  99. ncbi request reprint The role of Helicobacter pylori infection in children with acute immune thrombocytopenic purpura
    Tang Her Jaing
    Division of Hematology Oncology, Chang Gung Children s Hospital, Taoyuan, Taiwan
    Pediatr Blood Cancer 47:215-7. 2006
    ..Our prospective cohort studies found no statistically significant relation between H. pylori infection and acute ITP. There is therefore no indication to screen children with presumed acute ITP for H. pylori infection...
  100. ncbi request reprint Cutaneous lymphocytic vasculitis as the presenting feature of acute lymphoblastic leukemia
    Tang Her Jaing
    Division of Hematology and Oncology, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Pediatr Hematol Oncol 24:555-7. 2002
    ..Lymphocytic vasculitis may also reflect a new manifestation of host-leukemia interaction...
  101. doi request reprint Necrotizing pneumococcal pneumonia with bronchopleural fistula among children in Taiwan
    Yu Chia Hsieh
    Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    Pediatr Infect Dis J 30:740-4. 2011
    ..Histopathologic features of children receiving surgical resections of the lung because of BPF were analyzed to explore the pathogenesis of destructive lung disease caused by Streptococcus pneumoniae...