WenChieh Chen

Summary

Affiliation: Chang Gung Memorial Hospital
Country: Taiwan

Publications

  1. ncbi request reprint Partial unilateral lentiginosis with ipsilateral Lisch nodules and axillary freckling
    WenChieh Chen
    Department of Dermatology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Dermatology 209:321-4. 2004
  2. ncbi request reprint Expression of sex-determining genes in human sebaceous glands and their possible role in the pathogenesis of acne
    W Chen
    Department of Dermatology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    J Eur Acad Dermatol Venereol 20:846-52. 2006
  3. ncbi request reprint Alopecia areata universalis sparing nevus flammeus
    WenChieh Chen
    Department of Dermatology, Chang Gung University, Chang Gung Memorial Hospital, 83301 Kaohsiung, Taiwan
    Dermatology 210:227-8. 2005
  4. ncbi request reprint Mild cutaneous manifestation in two young women with extraordinary hyperandrogenemia
    WenChieh Chen
    Department of Dermatology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
    Dermatology 210:49-52. 2005
  5. ncbi request reprint Patients with a large prostate show a higher prevalence of androgenetic alopecia
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung ChangGung University, Niao Sung Hisang, 833 Kaohsiung, Taiwan
    Arch Dermatol Res 296:245-9. 2004
  6. ncbi request reprint Angioma serpiginosum arranged in a systematized segmental pattern suggesting mosaicism
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
    Dermatology 213:236-8. 2006
  7. ncbi request reprint Nail changes associated with chemotherapy in children
    W Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Centre, Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    J Eur Acad Dermatol Venereol 21:186-90. 2007
  8. ncbi request reprint Expression of sex-determining genes in the scalp of men with androgenetic alopecia
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC
    Dermatology 214:199-204. 2007
  9. ncbi request reprint Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: A cross-sectional study
    Chao Chun Yang
    Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan International Research Center of Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan
    J Am Acad Dermatol 70:297-302.e1. 2014
  10. ncbi request reprint Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes
    WenChieh Chen
    Department of Dermatology, College of Medicine, National Cheng Kung University, Sheng Li Road 138, 704 Tainan, Taiwan
    J Invest Dermatol 121:441-7. 2003

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Partial unilateral lentiginosis with ipsilateral Lisch nodules and axillary freckling
    WenChieh Chen
    Department of Dermatology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Dermatology 209:321-4. 2004
    ..This case provides further evidence in favor of the concept that partial unilateral lentiginosis represents a mosaic manifestation of type 1 neurofibromatosis...
  2. ncbi request reprint Expression of sex-determining genes in human sebaceous glands and their possible role in the pathogenesis of acne
    W Chen
    Department of Dermatology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    J Eur Acad Dermatol Venereol 20:846-52. 2006
    ..Factors regulating cutaneous steroidogenesis associated with disease status remain largely unknown...
  3. ncbi request reprint Alopecia areata universalis sparing nevus flammeus
    WenChieh Chen
    Department of Dermatology, Chang Gung University, Chang Gung Memorial Hospital, 83301 Kaohsiung, Taiwan
    Dermatology 210:227-8. 2005
    ..Our case gives further evidence to the notion that nevus as genetic mosaic may show genetically determined resistance to alopecia areata...
  4. ncbi request reprint Mild cutaneous manifestation in two young women with extraordinary hyperandrogenemia
    WenChieh Chen
    Department of Dermatology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
    Dermatology 210:49-52. 2005
    ..A careful patient history and a complete physical examination are mandatory in each individual female case with acne or alopecia. The possibility of adrenal tumor should be explored in patients with escalated circulating testosterone...
  5. ncbi request reprint Patients with a large prostate show a higher prevalence of androgenetic alopecia
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung ChangGung University, Niao Sung Hisang, 833 Kaohsiung, Taiwan
    Arch Dermatol Res 296:245-9. 2004
    ..Our results suggest that a larger prostate is associated with a higher prevalence of AGA. It remains to be seen if long-term use of finasteride in AGA patients will prophylactically lower the incidence of BPH...
  6. ncbi request reprint Angioma serpiginosum arranged in a systematized segmental pattern suggesting mosaicism
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
    Dermatology 213:236-8. 2006
    ..The systematized, segmental and asymmetric arrangement of lesions as noted in the present case suggest that angioma serpiginosum reflects genetic mosaicism...
  7. ncbi request reprint Nail changes associated with chemotherapy in children
    W Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Centre, Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    J Eur Acad Dermatol Venereol 21:186-90. 2007
    ..Large series of chemotherapy-induced nail changes in children have rarely been reported in the literature...
  8. ncbi request reprint Expression of sex-determining genes in the scalp of men with androgenetic alopecia
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC
    Dermatology 214:199-204. 2007
    ..The regulation of the cutaneous steroidogenesis in patients with androgenetic alopecia remains largely unclear...
  9. ncbi request reprint Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: A cross-sectional study
    Chao Chun Yang
    Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan International Research Center of Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan
    J Am Acad Dermatol 70:297-302.e1. 2014
    ..Obesity is a risk factor for multiple health problems, but its association with androgenetic alopecia (AGA) remains controversial...
  10. ncbi request reprint Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes
    WenChieh Chen
    Department of Dermatology, College of Medicine, National Cheng Kung University, Sheng Li Road 138, 704 Tainan, Taiwan
    J Invest Dermatol 121:441-7. 2003
    ..Treatment with linoleic acid for 48 h induced further differentiation of sebocytes leading to abundant lipid synthesis...
  11. ncbi request reprint Potent corticosteroids inhibit lipogenesis in sebaceous glands
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung, Chang Gung University, Taoyuon, Taiwan
    Dermatology 213:264-5. 2006
  12. doi request reprint Giant café-au-lait macule in neurofibromatosis 1: a type 2 segmental manifestation of neurofibromatosis 1?
    Chao Chun Yang
    Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    J Am Acad Dermatol 58:493-7. 2008
    ..This large café-au-lait macule may be best explained as an example of type 2 segmental NF1. A novel mutation (3009delG) in exon 23 was also identified in this patient, which has not yet been described in sporadic and familial NF1...
  13. doi request reprint Juvenile pityriasis rubra pilaris: report of 28 cases in Taiwan
    Chao Chun Yang
    Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    J Am Acad Dermatol 59:943-8. 2008
    ..Pityriasis rubra pilaris (PRP) is a papulosquamous dermatosis uncommon in juveniles. Large-scale studies are limited, especially from Asian countries...
  14. ncbi request reprint Phacomatosis pigmentovasculosebacea: an unusual case of phacomatosis multiplex
    WenChieh Chen
    Department of Dermatology, College of Medicine, National Cheng Kung University, 138 Sheng Li Road, 704 Tainan, Taiwan
    Eur J Dermatol 13:231-3. 2003
    ..The term "phacomatosis pigmentovasculosebacea" is proposed to describe the concurrence of these multiple nevi derived from pigmentary, vascular and epithelial cells...
  15. ncbi request reprint Testosterone synthesized in cultured human SZ95 sebocytes derives mainly from dehydroepiandrosterone
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital Kaohsiung Medical Center Chang Gung University, Kaohsiung, Taiwan
    Exp Dermatol 19:470-2. 2010
    ....
  16. ncbi request reprint Higher body mass index is a significant risk factor for acne formation in schoolchildren
    Min Chien Tsai
    Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung, Niao Sung, Kaohsiung, Chang Gung University, Taoyuon, Taiwan
    Eur J Dermatol 16:251-3. 2006
    ..Overall schoolchildren with a BMI < 18.5 had less prevalence rate of acne, especially the inflammatory lesions, while those with a BMI-for-age > or = 95% had a significantly higher rate of acne development...
  17. ncbi request reprint Neoplastic skin lesions of the scalp in children: a retrospective study of 265 cases in Taiwan
    Chao Chun Yang
    Department of Dermatology, Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Eur J Dermatol 24:70-5. 2014
    ..The preferential occurrence of certain skin neoplasms on the scalp of children raises concerns from their parents and warrants special diagnostic and therapeutic approaches...
  18. ncbi request reprint Cutaneous androgen metabolism: basic research and clinical perspectives
    WenChieh Chen
    Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    J Invest Dermatol 119:992-1007. 2002
    ..Pharmacologic development of more potent specific isoenzyme antagonists may lead to better clinical treatment or even prevention of androgen-dependent dermatoses...
  19. doi request reprint Nephrogenic systemic fibrosis in advanced chronic kidney disease: a single hospital's experience in Taiwan
    WenChieh Chen
    Department of Dermatology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan
    Eur J Dermatol 19:44-9. 2009
    ..The cause of a lower incidence rate in our series remains to be determined...
  20. ncbi request reprint Vesicular pemphigoid with circulating autoantibodies against 230-kDa and 180-kDa proteins, and additional autoantibodies against 97-kDa and 45-kDa proteins
    Feng Jie Lai
    Department of Dermatology, National Cheng Kung University, Tainan, Taiwan
    Int J Dermatol 46:206-9. 2007
    ..Treatment with systemic corticosteroid, minocycline and antihistamines plus topical steroid resulted in moderate improvement. A few vesicles, however, continued to appear intermittently during the past year of treatment...
  21. ncbi request reprint Febrile ulceronecrotic Mucha-Habermann disease with extensive skin necrosis in intertriginous areas
    Chao Chun Yang
    Department of Dermatology, College of Medicine, National Cheng Kung University, 138 Sheng Li Road, Tainan, Taiwan
    Eur J Dermatol 13:493-6. 2003
    ..Systemic administration of corticosteroid and erythromycin led to rapid healing of ulcerations without residual scar formation. Review of the literature showed male-predominance and favorable outcome in pediatric cases of FUMHD...
  22. doi request reprint Facial epidermal inclusion cysts are associated with smoking in men: a hospital-based case-control study
    Shang Hong Lin
    Department of Dermatology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Dermatol Surg 36:894-8. 2010
    ..Our clinical experience suggests that smoking may be a risk factor for the development of EICs. OBJECTIVE To determine whether the number and sites of EICs are related to smoking behavior and quantity...
  23. ncbi request reprint Combination of massive mucinosis, dermatomyositis, pyoderma gangrenosum-like ulcer, bullae and fatal intestinal vasculopathy in a young female
    Guan Yu Chen
    Department of Dermatology, Armed Forces Taichung General Hospital, 348, Sec 2, Chung Shan Road, Tai Ping, Taichung 411, Taiwan
    Eur J Dermatol 15:396-400. 2005
    ..In spite of aggressive treatment, the patient died 9 months after the disease onset, probably due to the complication of gastrointestinal ischemia and perforation...
  24. ncbi request reprint Dimorphic exanthema manifested as reticular maculopapular exanthema and erythema multiforme major associated with pyrazolon derivatives
    WenChieh Chen
    Department of Dermatology, College of Medicine, National Cheng Kung University, 138 Sheng Li Road, 704 Tainan, Taiwan
    Eur J Dermatol 12:488-90. 2002
    ..Patch testing showed negative reaction to the suspected drugs. The possible mechanism underlying the association of dimorphic exanthema with NSAIDs is discussed...
  25. ncbi request reprint High-dose steroid pulse therapy for the treatment of severe alopecia areata
    Ya Ming Tsai
    Department of Dermatology, College of Medicine, National Cheng Kung University, 138 Sheng Li Road, Tainan, Taiwan
    J Formos Med Assoc 101:223-6. 2002
    ..Our results indicated that steroid pulse therapy, given at 5-10 mg/kg once monthly for an average of 6 months, is effective and well tolerated in Taiwanese patients with severe multifocal AA lasting less than 2 years...
  26. ncbi request reprint Update and future of hormonal therapy in acne
    Diane Thiboutot
    Department of Dermatology, The Pennsylvania State University College of Medicine, Hershey, Penn, USA
    Dermatology 206:57-67. 2003
    ..The knowledge gained from this work may provide an impetus for future drug discovery in the hormonal treatment of acne and lead to improvements in the care of our patients with acne...
  27. ncbi request reprint Higher levels of steroidogenic acute regulatory protein and type I 3beta-hydroxysteroid dehydrogenase in the scalp of men with androgenetic alopecia
    WenChieh Chen
    J Invest Dermatol 126:2332-5. 2006
  28. ncbi request reprint Single transverse apparent leukonychia caused by 5-fluorouracil plus leucovorin
    Guan Yu Chen
    Dermatology 207:86-7. 2003
  29. ncbi request reprint Case of co-morbidity of alopecia areata and pityriasis lichenoides in a five year old boy for two years
    Min Chien Tsai
    J Dermatol 33:724-6. 2006
  30. ncbi request reprint Folliculitis decalvans associated with Micronychia
    Chao Chun Yang
    Dermatology 208:227-8. 2004
  31. ncbi request reprint Black lunula caused by Tegafur
    Guan Yu Chen
    Acta Derm Venereol 84:238-9. 2004
  32. pmc Corticotropin-releasing hormone: an autocrine hormone that promotes lipogenesis in human sebocytes
    Christos C Zouboulis
    Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, 14195 Berlin, Germany
    Proc Natl Acad Sci U S A 99:7148-53. 2002
    ..The findings implicate CRH in the clinical development of acne, seborrhea, androgenetic alopecia, skin aging, xerosis, and other skin disorders associated with alterations in lipid formation of sebaceous origin...