Jyh Ping Chen

Summary

Affiliation: Chang Gung University
Country: Taiwan

Publications

  1. ncbi request reprint Loofa sponge as a scaffold for culture of rat hepatocytes
    Jyh Ping Chen
    Graduate Institute of Biochemical and Biomedical Engineering and Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Biotechnol Prog 21:315-9. 2005
  2. pmc Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide
    Yu Jen Lu
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan
    Int J Nanomedicine 7:1737-47. 2012
  3. doi request reprint Incorporation of biphasic calcium phosphate microparticles in injectable thermoresponsive hydrogel modulates bone cell proliferation and differentiation
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Colloids Surf B Biointerfaces 110:120-9. 2013
  4. pmc Targeted delivery of tissue plasminogen activator by binding to silica-coated magnetic nanoparticle
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan, Republic of China
    Int J Nanomedicine 7:5137-49. 2012
  5. pmc Preparation and characterization of biomimetic silk fibroin/chitosan composite nanofibers by electrospinning for osteoblasts culture
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei Shan, Tao Yuan, Taiwan, 333, Republic of China
    Nanoscale Res Lett 7:170. 2012
  6. doi request reprint Surface modification of electrospun PLLA nanofibers by plasma treatment and cationized gelatin immobilization for cartilage tissue engineering
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan, ROC
    Acta Biomater 7:234-43. 2011
  7. doi request reprint Optimization of biodiesel production catalyzed by fungus cells immobilized in fibrous supports
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, Republic of China
    Appl Biochem Biotechnol 161:181-94. 2010
  8. ncbi request reprint Latex particles with thermo-flocculation and magnetic properties for immobilization of alpha-chymotrypsin
    J P Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, Republic of China
    Biotechnol Prog 17:369-75. 2001
  9. doi request reprint Bioethanol production from uncooked raw starch by immobilized surface-engineered yeast cells
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Taoyuan, Taiwan, Republic of China
    Appl Biochem Biotechnol 145:59-67. 2008
  10. ncbi request reprint Thermo-responsive chitosan-graft-poly(N-isopropylacrylamide) injectable hydrogel for cultivation of chondrocytes and meniscus cells
    Jyh Ping Chen
    Graduate Institute of Biochemical and Biomedical Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan ROC
    Macromol Biosci 6:1026-39. 2006

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Loofa sponge as a scaffold for culture of rat hepatocytes
    Jyh Ping Chen
    Graduate Institute of Biochemical and Biomedical Engineering and Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Biotechnol Prog 21:315-9. 2005
    ..Both urea-N synthesis and albumin secretion rates could be maintained up to 7 days for cells immobilized within LS and spheroid-like cell aggregates could be found after the second day...
  2. pmc Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide
    Yu Jen Lu
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan
    Int J Nanomedicine 7:1737-47. 2012
    ..Immobilization of BCNU on a nanocarrier might increase the thermal stability of BCNU and extend its half-life...
  3. doi request reprint Incorporation of biphasic calcium phosphate microparticles in injectable thermoresponsive hydrogel modulates bone cell proliferation and differentiation
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Colloids Surf B Biointerfaces 110:120-9. 2013
    ..From in vivo nude mice subcutaneous implantation experiments, the injected cell mass can form ectopic bone tissue in HA-CPN/BCP hydrogel composite. ..
  4. pmc Targeted delivery of tissue plasminogen activator by binding to silica-coated magnetic nanoparticle
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan, Republic of China
    Int J Nanomedicine 7:5137-49. 2012
    ..An amine-terminated surface silanizing agent (3-aminopropyltrimethoxysilane) was used to functionalize the SiO(2) surface, which provides abundant -NH(2) functional groups for conjugating with tPA...
  5. pmc Preparation and characterization of biomimetic silk fibroin/chitosan composite nanofibers by electrospinning for osteoblasts culture
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei Shan, Tao Yuan, Taiwan, 333, Republic of China
    Nanoscale Res Lett 7:170. 2012
    ..SF promotes hFOB proliferation while CS enhances hFOB differentiation. The composite SF/CS NFs will be suitable for bone tissue engineering applications by choosing a suitable blend composition.PACS: 87.85.jf; 87.85.Rs; 68.37.Hk...
  6. doi request reprint Surface modification of electrospun PLLA nanofibers by plasma treatment and cationized gelatin immobilization for cartilage tissue engineering
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan, ROC
    Acta Biomater 7:234-43. 2011
    ..Subcutaneous implantation of the cell-scaffold constructs with autologous chondrocytes also confirmed the formation of ectopic cartilage tissues after 28 days by histological examination and immunostaining...
  7. doi request reprint Optimization of biodiesel production catalyzed by fungus cells immobilized in fibrous supports
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, Republic of China
    Appl Biochem Biotechnol 161:181-94. 2010
    ..64 molar ratio of methanol to oil, 2.25% (w/w) cell weight, and 23.3 h reaction time, the predicted value of yield was 72.6%. Validation experiments with yields of 70.77 +/- 2.46% verified the availability and the accuracy of the model...
  8. ncbi request reprint Latex particles with thermo-flocculation and magnetic properties for immobilization of alpha-chymotrypsin
    J P Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, Republic of China
    Biotechnol Prog 17:369-75. 2001
    ....
  9. doi request reprint Bioethanol production from uncooked raw starch by immobilized surface-engineered yeast cells
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Taoyuan, Taiwan, Republic of China
    Appl Biochem Biotechnol 145:59-67. 2008
    ..Adding cells to the bioreactor could partially restore ethanol production to 75% of its initial value...
  10. ncbi request reprint Thermo-responsive chitosan-graft-poly(N-isopropylacrylamide) injectable hydrogel for cultivation of chondrocytes and meniscus cells
    Jyh Ping Chen
    Graduate Institute of Biochemical and Biomedical Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan ROC
    Macromol Biosci 6:1026-39. 2006
    ..The hydrogel not only preserves the viability and phenotypic morphology of the entrapped cells but also stimulates the initial cell-cell interactions...
  11. ncbi request reprint Dynamic seeding and perfusion culture of hepatocytes with galactosylated vegetable sponge in packed-bed bioreactor
    Jyh Ping Chen
    Graduate Institute of Biochemical and Biomedical Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    J Biosci Bioeng 102:41-5. 2006
    ..The hepatocytes showed an increasing albumin production rate from 49 to 109 microg/10(6) cells/d over the 7-d culture...
  12. doi request reprint Osteogenic differentiation and ectopic bone formation of canine bone marrow-derived mesenchymal stem cells in injectable thermo-responsive polymer hydrogel
    Han Tsung Liao
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan, Taiwan, Republic of China
    Tissue Eng Part C Methods 17:1139-49. 2011
    ..Taken together, the results indicate the feasibility and efficacy of HA-CPN hydrogel as an injectable bone tissue engineering scaffold with cBMSCs...
  13. ncbi request reprint Laser sintered porous polycaprolacone scaffolds loaded with hyaluronic acid and gelatin-grafted thermoresponsive hydrogel for cartilage tissue engineering
    Ming Yih Lee
    Graduate Institute of Medical Mechatronics, Chang Gung University, Taiwan, ROC
    Biomed Mater Eng 23:533-43. 2013
    ..This study suggests that a soft/hard bi-phase scaffold may be used for cartilage tissue engineering to enhance in vitro chondrogenesis. ..
  14. doi request reprint Thermosensitive hydrogels composed of hyaluronic acid and gelatin as carriers for the intravesical administration of cisplatin
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kweishan, Taoyuan, Taiwan
    J Pharm Sci 100:655-66. 2011
    ..PNIPAM caused partial desquamation of umbrella cells. The thermosensitive hydrogels prepared in this study may be promising carriers for targeted drug delivery to the bladder...
  15. ncbi request reprint Loofa sponge as a scaffold for the culture of human hepatocyte cell line
    Jyh Ping Chen
    Graduate Institute of Biochemical and Biomedical Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Biotechnol Prog 19:522-7. 2003
    ..These experimental results and observations by SEM suggested that loofa sponge is a suitable scaffold for high-density culture of human hepatocyte cell line and the immobilized cells could express high levels of liver-specific functions...
  16. ncbi request reprint Temperature-sensitive hydrogels composed of chitosan and hyaluronic acid as injectable carriers for drug delivery
    Jia You Fang
    Pharmaceutics Laboratory, Chang Gung University, Taoyuan, Taiwan
    Eur J Pharm Biopharm 68:626-36. 2008
    ..CPN and CPNHA prolonged the analgesic duration of nalbuphine with no influence on the onset time. The loading of nalbuphine in the CPNHA hydrogel exhibited the longest analgesic duration (4h) among the 3 hydrogels tested...
  17. ncbi request reprint Characterization and evaluation of silk protein hydrogels for drug delivery
    Jia You Fang
    Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan
    Chem Pharm Bull (Tokyo) 54:156-62. 2006
    ..Furthermore, SPH as an adjuvant polymer in PF-127 and chitosan hydrogels lowered and controlled the amount of drug released from those systems...
  18. ncbi request reprint Preparation and characterization of gelatin/hyaluronic acid cryogels for adipose tissue engineering: in vitro and in vivo studies
    Kun Hung Chang
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Acta Biomater 9:9012-26. 2013
    ....
  19. ncbi request reprint Bioactive collagen-grafted poly-L-lactic acid nanofibrous membrane for cartilage tissue engineering
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Taoyuan 333, Taiwan, Republic of China
    J Nanosci Nanotechnol 10:5393-8. 2010
    ....
  20. doi request reprint Dual targeted delivery of doxorubicin to cancer cells using folate-conjugated magnetic multi-walled carbon nanotubes
    Yu Jen Lu
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Colloids Surf B Biointerfaces 89:1-9. 2012
    ..These properties make the magnetic nanocarrier a potential candidate for targeted delivery of DOX for cancer treatment...
  21. doi request reprint Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles
    Yunn Hwa Ma
    Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, 259 Wen Hwa 1st Road, Kuei Shan, Tao Yuan 33302, Taiwan, ROC
    Biomaterials 30:3343-51. 2009
    ....
  22. ncbi request reprint The delivery of platinum drugs from thermosensitive hydrogels containing different ratios of chitosan
    Jia You Fang
    Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan, Taiwan
    Drug Deliv 15:235-43. 2008
    ..Thermosensitive hydrogels like those prepared in this study may be a promising carrier for the delivery of platinum drugs, as the drug release can be controlled and sustained using CPN networks...
  23. ncbi request reprint Surface modification of polycaprolactone scaffolds fabricated via selective laser sintering for cartilage tissue engineering
    Chih Hao Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kweishan, Taoyuan 333, Taiwan, ROC Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Craniofacial Research Center, Chang Gung University, Kweishann, Taoyuan 333, Taiwan, ROC
    Mater Sci Eng C Mater Biol Appl 40:389-97. 2014
    ..We conclude that collagen surface modification through immersion coating on SLS-manufactured scaffolds is a feasible scaffold for cartilage tissue engineering in craniofacial reconstruction...
  24. ncbi request reprint Superparamagnetic iron oxide nanoparticles for delivery of tissue plasminogen activator
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University Kwei san, Taoyuan 333, Taiwan, ROC
    J Nanosci Nanotechnol 11:11089-94. 2011
    ..The optimum drug loading could be achieved by contacting 0.25 mg rtPA with 5 mg CMD-MNP where all rtPA is immobilized to the magnetic nanocarrier with full retention of its thrombolytic activity...
  25. ncbi request reprint Selective laser sintered poly-ε-caprolactone scaffold hybridized with collagen hydrogel for cartilage tissue engineering
    Chih Hao Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Tao Yuan 33302, Taiwan, Republic of China Craniofacial Research Center, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Tao Yuan 33302, Taiwan, Republic of China
    Biofabrication 6:015004. 2014
    ..Collagen-gel-suspended chondrocytes loaded in SLS-manufactured PCL scaffolds may provide a means of producing tissue-engineered cartilage with customized shapes and designs via AM technology. ..
  26. doi request reprint Preparation and characterization of composite nanofibers of polycaprolactone and nanohydroxyapatite for osteogenic differentiation of mesenchymal stem cells
    Jyh Ping Chen
    Department of Chemical and Materials Engineering, Chang Gung University, Kwei San, Taoyuan 333, Taiwan, ROC
    Colloids Surf B Biointerfaces 86:169-75. 2011
    ..The present study indicated that electrospun composite PCL/nHAP nanofibrous membranes are suitable for mineralization of MSCs intended for bone tissue engineering...