J C Chen

Summary

Affiliation: Chang Gung University
Country: Taiwan

Publications

  1. pmc Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation
    Han Ting Chen
    Department of Physiology and Pharmacology, Institute of Biomedical Sciences, Chang Gung University, 259 Wen Hwa 1st Road, Tao Yuan, Taiwan, ROC
    ASN Neuro 4:371-82. 2012
  2. pmc NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes
    Chih Chung Lin
    Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, 259 Wen Hwa 1st Road, Kwei San, Tao Yuan, Taiwan
    Cell Commun Signal 10:35. 2012
  3. pmc Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study
    Ya Tin Lin
    Department of Physiology and Pharmacology, Chang Gung University, Taiwan, Republic of China
    J Neuroinflammation 8:126. 2011
  4. ncbi request reprint Molecular mechanisms of psychostimulant addiction
    Jin Chung Chen
    Neuropharmacology Laboratory, Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Chang Gung Med J 32:148-54. 2009
  5. ncbi request reprint Down-regulation of the glial glutamate transporter GLT-1 in rat hippocampus and striatum and its modulation by a group III metabotropic glutamate receptor antagonist following transient global forebrain ischemia
    Jin Chung Chen
    Department of Pharmacology, Chang Gung University, 259 Wen Hwa 1st Road, Tao Yuan, Kwei Shan, Taiwan, ROC
    Neuropharmacology 49:703-14. 2005
  6. ncbi request reprint Significance of glutamate and dopamine neurons in the ventral pallidum in the expression of behavioral sensitization to amphetamine
    J C Chen
    Department of Pharmacology, Chang Gung University, Tao Yuian, Taiwan, ROC
    Life Sci 68:973-83. 2001
  7. ncbi request reprint Reductions in binding and functions of D2 dopamine receptors in the rat ventral striatum during amphetamine sensitization
    J C Chen
    Department of Pharmacology, Chang Gung University, Tao Yuan, Taiwan, ROC
    Life Sci 64:343-54. 1999
  8. ncbi request reprint Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the levels of neurotransmitters in the medial prefrontal cortex
    J C Chen
    Laboratory of Neuropharmacology, Department of Pharmacology, Chang Gung University, Tao Yuan 333, Taiwan
    Brain Res 816:220-4. 1999
  9. ncbi request reprint Endomorphin-1 and -2 induce naloxone-precipitated withdrawal syndromes in rats
    J C Chen
    Department of Pharmacology, Chang Gung University, 259 Wen Hua 1st Road, Kwei Shan, 333, Tao Yuan, Taiwan, ROC
    Peptides 24:477-81. 2003
  10. ncbi request reprint Differential effects of endomorphin-1 and -2 on amphetamine sensitization: neurochemical and behavioral aspects
    J C Chen
    Department of Pharmacology, Chang-Gung University, Tao-Yuan, Kwei-Shan, Taiwan, ROC
    Synapse 39:239-48. 2001

Collaborators

  • J Y Li
  • P L Tao
  • H E Wang
  • S Y Wang
  • Long Sun Ro
  • H Chang
  • S C Lee
  • C H Chiu
  • Yao Chang Chiang
  • S M Yu
  • Chih Chung Lin
  • Han Ting Chen
  • Y L Chen
  • Ya Tin Lin
  • R S Liu
  • C H Hsieh
  • Y Y I Shih
  • B Vaseeharan
  • E Y K Huang
  • M F Chen
  • C A Chang
  • Tzu Yung Lin
  • S H Chiou
  • H M Chen
  • Chuen Mao Yang
  • Hsi Lung Hsieh
  • Y J Lee
  • D T W Tan
  • Ruey Horng Shih
  • Shin Ei Cheng
  • Nan Yu Ruan
  • L T Lin
  • Pei Ling Chi
  • C C Luo
  • H Y Li
  • F S Jaw
  • Y Y Chen
  • C H Huang
  • C Chang
  • T Murugan
  • T Prem Anand
  • P P C Tan
  • C H Wong
  • C J Ng
  • D F Chiu
  • J N Lin
  • M H Shyr

Detail Information

Publications20

  1. pmc Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation
    Han Ting Chen
    Department of Physiology and Pharmacology, Institute of Biomedical Sciences, Chang Gung University, 259 Wen Hwa 1st Road, Tao Yuan, Taiwan, ROC
    ASN Neuro 4:371-82. 2012
    ..In addition, in vivo Akt activity in the ventral striatum appears to play an important role in systemic D2/D3 agonist-induced behavioural activation...
  2. pmc NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes
    Chih Chung Lin
    Department of Physiology and Pharmacology and Health Aging Research Center, College of Medicine, Chang Gung University, 259 Wen Hwa 1st Road, Kwei San, Tao Yuan, Taiwan
    Cell Commun Signal 10:35. 2012
    ..abstract:..
  3. pmc Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study
    Ya Tin Lin
    Department of Physiology and Pharmacology, Chang Gung University, Taiwan, Republic of China
    J Neuroinflammation 8:126. 2011
    ..The aim of this study was to investigate whether and how BDNF-trkB signaling in the DRG is involved in the process of inflammatory pain...
  4. ncbi request reprint Molecular mechanisms of psychostimulant addiction
    Jin Chung Chen
    Neuropharmacology Laboratory, Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Chang Gung Med J 32:148-54. 2009
    ..This review outlines the cellular pathways that have been demonstrated to participate in psychostimulant addiction, focused particularly in the nucleus accumbens...
  5. ncbi request reprint Down-regulation of the glial glutamate transporter GLT-1 in rat hippocampus and striatum and its modulation by a group III metabotropic glutamate receptor antagonist following transient global forebrain ischemia
    Jin Chung Chen
    Department of Pharmacology, Chang Gung University, 259 Wen Hwa 1st Road, Tao Yuan, Kwei Shan, Taiwan, ROC
    Neuropharmacology 49:703-14. 2005
    ..The current findings pinpoint the significance of GLT-1 during ischemia/reperfusion and suggest a potential application of group III metabotropic glutamate receptor antagonist against ischemic/hypoxic neuronal damage...
  6. ncbi request reprint Significance of glutamate and dopamine neurons in the ventral pallidum in the expression of behavioral sensitization to amphetamine
    J C Chen
    Department of Pharmacology, Chang Gung University, Tao Yuian, Taiwan, ROC
    Life Sci 68:973-83. 2001
    ..Taken together, the current results suggest that the excitatory amino acid in the VP plays a significant role during the expression of behavioral sensitization to amphetamine...
  7. ncbi request reprint Reductions in binding and functions of D2 dopamine receptors in the rat ventral striatum during amphetamine sensitization
    J C Chen
    Department of Pharmacology, Chang Gung University, Tao Yuan, Taiwan, ROC
    Life Sci 64:343-54. 1999
    ..The decrease of D2 receptors might reflect cellular mechanisms underlying the expression of amphetamine sensitization...
  8. ncbi request reprint Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the levels of neurotransmitters in the medial prefrontal cortex
    J C Chen
    Laboratory of Neuropharmacology, Department of Pharmacology, Chang Gung University, Tao Yuan 333, Taiwan
    Brain Res 816:220-4. 1999
    ..The results suggest that NPFF may modulate the neuronal process of amphetamine addiction...
  9. ncbi request reprint Endomorphin-1 and -2 induce naloxone-precipitated withdrawal syndromes in rats
    J C Chen
    Department of Pharmacology, Chang Gung University, 259 Wen Hua 1st Road, Kwei Shan, 333, Tao Yuan, Taiwan, ROC
    Peptides 24:477-81. 2003
    ..The present results indicate EM-1 and EM-2 could initiate certain mechanism involved opiate dependence...
  10. ncbi request reprint Differential effects of endomorphin-1 and -2 on amphetamine sensitization: neurochemical and behavioral aspects
    J C Chen
    Department of Pharmacology, Chang-Gung University, Tao-Yuan, Kwei-Shan, Taiwan, ROC
    Synapse 39:239-48. 2001
    ..The results also demonstrate that there are differential responses between endomorphin-1 and -2 on behavioral amphetamine sensitization and the underlying neurochemical substrates...
  11. pmc Remnant living cells that escape cell loss in late-stage tumors exhibit cancer stem cell-like characteristics
    Y L Chen
    Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, ROC
    Cell Death Dis 3:e399. 2012
    ..Taken together, the current data suggested that cells escaping from cell loss in late-stage tumors exhibit CSC-like characteristics, and HSV1-tk may be considered a theranostic agent for targeting this population in vivo...
  12. doi request reprint Brain nociceptive imaging in rats using (18)f-fluorodeoxyglucose small-animal positron emission tomography
    Y Y I Shih
    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China
    Neuroscience 155:1221-6. 2008
    ..The present protocol allowed identification of the brain areas involved in pain processing, and should be useful in further evaluations of the effects of new drugs and preclinical therapies for pain...
  13. ncbi request reprint Effect of N(G)-nitro-L-arginine methyl ester on intestinal permeability following intestinal ischemia-reperfusion injury in a rat model
    C C Luo
    Department of Pediatric Surgery and Pediatrics, Chang Gung Children s Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Biol Neonate 80:60-3. 2001
    ..These results suggest that endogenous NO may play a role in the protecting intestinal integrity after IRI...
  14. doi request reprint Prognostic value of 18-FDG uptake in early stage NSCLC
    J C Chen
    Surgery, Tri Service General Hospital, Taipei 114, Taiwan, Republic of China
    Thorac Cardiovasc Surg 57:413-6. 2009
    ..We assessed whether the standard uptake of 18-fluorodeoxyglucose (18-FDG) in non-small cell lung cancers (NSCLC) differed between stage I and non-stage I tumors...
  15. doi request reprint Nitric oxide and interleukin-1beta mediate noradrenergic induced corticotrophin-releasing hormone release in organotypic cultures of rat paraventricular nucleus
    C H Hsieh
    Graduate Institute of Biomedical Sciences, Chang Gung University, Tao Yuan, Taiwan
    Neuroscience 165:1191-202. 2010
    ..In summary, the current study demonstrates that IL-1beta plays a significant role in NE-induced CRH release, and that neuroendocrine response in the PVN may depend on local NO action...
  16. ncbi request reprint Modulations of spinal serotonin activity affect the development of morphine tolerance
    J Y Li
    Department of Anesthesiology, Chang-Gung Memorial Hospital, Taiwan, ROC
    Anesth Analg 92:1563-8. 2001
    ..We conclude that activity of spinal 5-HT-containing neurons plays a crucial role during the development of morphine tolerance...
  17. ncbi request reprint Dansyl-PQRamide, a possible neuropeptide FF receptor antagonist, induces conditioned place preference
    E Y K Huang
    Department of Pharmacology, National Defense Medical Center, Nei Hu 114, Taipei, Taiwan, ROC
    Peptides 23:489-96. 2002
    ..These results also reveal a close relationship between NPFF, drug rewarding and the dopaminergic and serotoninergic neurons in the mesolimbic system...
  18. ncbi request reprint Mechanism of extracellular ATP-induced proliferation of vascular smooth muscle cells
    S M Yu
    Department of Pharmacology, Chang Gung College of Medicine and Technology, Kwei San, Tao Yuan, Taiwan
    Mol Pharmacol 50:1000-9. 1996
    ..PKC and, in turn, Raf-1 and MAPK were then activated, leading eventually to DNA synthesis and cell proliferation...
  19. ncbi request reprint Shrimp vaccination trials with the VP292 protein of white spot syndrome virus
    B Vaseeharan
    Department of Advanced Zoology and Biotechnology, Sivanthi Adithanar College, Nagercoil, Tamil Nadu, India
    Lett Appl Microbiol 43:137-42. 2006
    ..Construction of a recombinant vector that expresses VP292 protein of white spot syndrome virus (WSSV) and to exploit the possibility of obtaining the vaccine conferring protection against WSSV infection in shrimps...
  20. ncbi request reprint Prostacyclin analogue (OP-2507) induces delayed ex vivo neutrophil apoptosis and attenuates reperfusion-induced hepatic microcirculatory derangement in rats
    M F Chen
    Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan
    Shock 16:473-8. 2001
    ..This study demonstrates that OP-2507 treatment with ischemia may ameliorate the ischemia-reperfusion injury of the liver in the rat model, and increase spontaneous neutrophil apoptosis ex vivo...