Sung Chou Li

Summary

Affiliation: Academia Sinica
Country: Taiwan

Publications

  1. pmc UMARS: Un-MAppable Reads Solution
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    BMC Bioinformatics 12:S9. 2011
  2. pmc Discovery and characterization of medaka miRNA genes by next generation sequencing platform
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    BMC Genomics 11:S8. 2010
  3. doi request reprint Interrogation of rabbit miRNAs and their isomiRs
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    Genomics 98:453-9. 2011
  4. doi request reprint Identification of homologous microRNAs in 56 animal genomes
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    Genomics 96:1-9. 2010
  5. pmc Bioinformatic discovery of microRNA precursors from human ESTs and introns
    Sung Chou Li
    Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, Republic of China
    BMC Genomics 7:164. 2006
  6. doi request reprint Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer
    Kuo Wang Tsai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China
    Int J Cancer 129:2600-10. 2011
  7. doi request reprint MetaMirClust: discovery of miRNA cluster patterns using a data-mining approach
    Wen Ching Chan
    Institute of Biomedical Informatics, National Yang Ming University, Academia Sinica, Taipei, Taiwan, ROC
    Genomics 100:141-8. 2012
  8. pmc Transcriptional regulation of miR-196b by ETS2 in gastric cancer cells
    Yu Lun Liao
    Institute of Biomedical Sciences, Academic Sinica, Nankang, Taipei 115, Taiwan, Republic of China
    Carcinogenesis 33:760-9. 2012
  9. ncbi request reprint Aberrant expression of miR-196a in gastric cancers and correlation with recurrence
    Kuo Wang Tsai
    Department of Medical Education and Research, KaohsiungVeterans General Hospital, Kaohsiung, Taiwan, Republic of China
    Genes Chromosomes Cancer 51:394-401. 2012
  10. doi request reprint Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer
    Wei Shone Chen
    Department of Surgery, Veterans General Hospital, Taipei, Taiwan, ROC
    Oncol Rep 28:1069-76. 2012

Collaborators

Detail Information

Publications17

  1. pmc UMARS: Un-MAppable Reads Solution
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    BMC Bioinformatics 12:S9. 2011
    ..However, a fraction of NGS reads failed to be mapped back to the reference sequences. Such un-mappable reads are usually imputed to sequencing errors and discarded without further consideration...
  2. pmc Discovery and characterization of medaka miRNA genes by next generation sequencing platform
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    BMC Genomics 11:S8. 2010
    ..It is beneficial to conduct a genome-wide miRNA discovery study using the next generation sequencing (NGS) technology, which has emerged as a powerful sequencing tool for high-throughput analysis...
  3. doi request reprint Interrogation of rabbit miRNAs and their isomiRs
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    Genomics 98:453-9. 2011
    ..Moreover, we further performed additional small RNA libraries and defined miRNAs differentially expressed between brain and heart. We conclude also that isomiR distribution profiles could vary between brain and heart tissues...
  4. doi request reprint Identification of homologous microRNAs in 56 animal genomes
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    Genomics 96:1-9. 2010
    ..Our prediction pipeline allows the rapid and effective discovery of homologous miRNAs in a large number of genomes...
  5. pmc Bioinformatic discovery of microRNA precursors from human ESTs and introns
    Sung Chou Li
    Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, Republic of China
    BMC Genomics 7:164. 2006
    ..To overcome this problem, we examined expressed transcripts - ESTs and intronic sequences - to identify novel miRNAs as well as their target genes...
  6. doi request reprint Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer
    Kuo Wang Tsai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China
    Int J Cancer 129:2600-10. 2011
    ..In summary, our study shows that tumor-specific methylation silences miR-34b and miR-129 in gastric cancer cells...
  7. doi request reprint MetaMirClust: discovery of miRNA cluster patterns using a data-mining approach
    Wen Ching Chan
    Institute of Biomedical Informatics, National Yang Ming University, Academia Sinica, Taipei, Taiwan, ROC
    Genomics 100:141-8. 2012
    ..Therefore, the MetaMirClust database provides a useful bioinformatic resource for biologists to facilitate the advanced interrogations on the composition of miRNA clusters and their evolution patterns...
  8. pmc Transcriptional regulation of miR-196b by ETS2 in gastric cancer cells
    Yu Lun Liao
    Institute of Biomedical Sciences, Academic Sinica, Nankang, Taipei 115, Taiwan, Republic of China
    Carcinogenesis 33:760-9. 2012
    ..This finding could be beneficial for the development of effective cancer diagnostic and alternative therapeutic strategies...
  9. ncbi request reprint Aberrant expression of miR-196a in gastric cancers and correlation with recurrence
    Kuo Wang Tsai
    Department of Medical Education and Research, KaohsiungVeterans General Hospital, Kaohsiung, Taiwan, Republic of China
    Genes Chromosomes Cancer 51:394-401. 2012
    ..Altogether, our data demonstrate that miR-196a exerts an oncogenic role in gastric cancer and miR-196a may be a novel biomarker for detecting gastric cancer and for monitoring disease recurrence...
  10. doi request reprint Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer
    Wei Shone Chen
    Department of Surgery, Veterans General Hospital, Taipei, Taiwan, ROC
    Oncol Rep 28:1069-76. 2012
    ..In conclusion, epigenetic repression of the miR-1-133a cluster may play a critical role in colorectal cancer metastasis by silencing TAGLN2...
  11. pmc miRNA arm selection and isomiR distribution in gastric cancer
    Sung Chou Li
    Genomics Research Center, Academia Sinica, Taipei, Taiwan
    BMC Genomics 13:S13. 2012
    ..However, the precise mechanism and biology involved in the mature miRNA molecules are not clearly investigated. In this study, we conducted in-depth analyses to examine the arm selection and isomiRs using NGS platform...
  12. pmc MicroRNA 3' end nucleotide modification patterns and arm selection preference in liver tissues
    Sung Chou Li
    Genomics Research Center, Academia Sinica, Taipei, Taiwan
    BMC Syst Biol 6:S14. 2012
    ..To understand the mechanism better, we downloaded small RNA sequence reads from NCBI SRA and quantified the expression profiles of miRNAs in normal and tumor liver tissues...
  13. pmc Comprehensive analysis of microRNAs in breast cancer
    Hong Tai Chang
    Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China
    BMC Genomics 13:S18. 2012
    ..This study used bioinformatics and experimental approaches to conduct detailed analysis of the dysregulated miRNAs, arm selection preferences, 3' end modifications, and position shifts in isoforms of miRNAs (isomiRs) in breast cancer...
  14. doi request reprint Epigenetic regulation of miR-196b expression in gastric cancer
    Kuo Wang Tsai
    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
    Genes Chromosomes Cancer 49:969-80. 2010
    ..Our results provide important information on miR-196s regulation and demonstrate that abnormal DNA hypomethylation induces overexpression of miR-196b in gastric cancer...
  15. ncbi request reprint Intronic microRNA: discovery and biological implications
    Sung Chou Li
    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China
    DNA Cell Biol 26:195-207. 2007
    ....
  16. ncbi request reprint MicroRNA dysregulation in gastric cancer
    Hung Wei Pan
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China
    Curr Pharm Des 19:1273-84. 2013
    ..Additionally, this paper outlines the applications of miRNAs in clinical practice, such as diagnosis, prognosis, detection, and therapy of gastric cancer...
  17. pmc Vir-Mir db: prediction of viral microRNA candidate hairpins
    Sung Chou Li
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan, Republic of China
    Nucleic Acids Res 36:D184-9. 2008
    ..The viral miRNA prediction database (Vir-Mir) can be accessed via http://alk.ibms.sinica.edu.tw...