Ming Hong Tai

Summary

Publications

  1. pmc Up-regulation of hepatoma-derived growth factor facilitates tumor progression in malignant melanoma [corrected]
    Han En Tsai
    Institute of Biomedical Science, National Sun Yat Sen University, Kaohsiung, Taiwan
    PLoS ONE 8:e59345. 2013
  2. pmc Inhibition of choroidal neovascularization by topical application of angiogenesis inhibitor vasostatin
    Shwu Jiuan Sheu
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Mol Vis 15:1897-905. 2009
  3. pmc Topical application of recombinant calreticulin peptide, vasostatin 48, alleviates laser-induced choroidal neovascularization in rats
    Youn Shen Bee
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Mol Vis 16:756-67. 2010
  4. pmc Ultraviolet C Irradiation Induces Different Expression of Cyclooxygenase 2 in NIH 3T3 Cells and A431 Cells: The Roles of COX-2 Are Different in Various Cell Lines
    Ming Hong Tai
    Institute of Biomedical Sciences, National Sun Yat Sen University, Kaohsiung 80424, Taiwan E mail
    Int J Mol Sci 13:4351-66. 2012
  5. ncbi request reprint Inhibition of corneal angiogenesis by local application of vasostatin
    Pei Chang Wu
    Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Mol Vis 11:28-35. 2005
  6. ncbi request reprint Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma
    Tsung Hui Hu
    Division of Hepatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Cancer 97:1929-40. 2003
  7. ncbi request reprint Suppression of choroidal neovascularization by intramuscular polymer-based gene delivery of vasostatin
    Shwu Jiuan Sheu
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, ROC
    Exp Eye Res 81:673-9. 2005
  8. doi request reprint Systemic pro-opiomelanocortin expression induces melanogenic differentiation and inhibits tumor angiogenesis in established mouse melanoma
    Guei Sheung Liu
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan
    Hum Gene Ther 22:325-35. 2011
  9. doi request reprint Tumorigenesis and prognostic role of hepatoma-derived growth factor in human gliomas
    Shu Shong Hsu
    Division of Neurosurgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC
    J Neurooncol 107:101-9. 2012
  10. ncbi request reprint Gene delivery of endothelial nitric oxide synthase into nucleus tractus solitarii induces biphasic response in cardiovascular functions of hypertensive rats
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Am J Hypertens 17:63-70. 2004

Collaborators

Detail Information

Publications50

  1. pmc Up-regulation of hepatoma-derived growth factor facilitates tumor progression in malignant melanoma [corrected]
    Han En Tsai
    Institute of Biomedical Science, National Sun Yat Sen University, Kaohsiung, Taiwan
    PLoS ONE 8:e59345. 2013
    ..The present study provides evidence that HDGF promotes tumor progression of melanoma and targeting HDGF may constitute a novel strategy for the treatment of melanoma...
  2. pmc Inhibition of choroidal neovascularization by topical application of angiogenesis inhibitor vasostatin
    Shwu Jiuan Sheu
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Mol Vis 15:1897-905. 2009
    ..Choroidal neovascularization (CNV) is the leading cause of blindness in patients with age-related macular degeneration (AMD). This study evaluated the inhibitory effect of vasostatin (VS), an endogenous angiogenesis inhibitor, on CNV...
  3. pmc Topical application of recombinant calreticulin peptide, vasostatin 48, alleviates laser-induced choroidal neovascularization in rats
    Youn Shen Bee
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Mol Vis 16:756-67. 2010
    ..Vasostatin 48 (VS48) is a peptide of 48 amino acids derived from calreticulin. This study aimed to investigate the effects of topical application of VS48 eyedrops on experimental choroidal neovascularization (CNV)...
  4. pmc Ultraviolet C Irradiation Induces Different Expression of Cyclooxygenase 2 in NIH 3T3 Cells and A431 Cells: The Roles of COX-2 Are Different in Various Cell Lines
    Ming Hong Tai
    Institute of Biomedical Sciences, National Sun Yat Sen University, Kaohsiung 80424, Taiwan E mail
    Int J Mol Sci 13:4351-66. 2012
    ..Besides, COX-2 might play different roles in cellular response to UVC irradiation in various cell lines...
  5. ncbi request reprint Inhibition of corneal angiogenesis by local application of vasostatin
    Pei Chang Wu
    Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Mol Vis 11:28-35. 2005
    ..This study was designed to investigate the effects of the locally supplied endogenous angiogenesis inhibitor vasostatin (VS) on corneal angiogenesis...
  6. ncbi request reprint Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma
    Tsung Hui Hu
    Division of Hepatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Cancer 97:1929-40. 2003
    ..However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized...
  7. ncbi request reprint Suppression of choroidal neovascularization by intramuscular polymer-based gene delivery of vasostatin
    Shwu Jiuan Sheu
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, ROC
    Exp Eye Res 81:673-9. 2005
    ..001) for at least 42 days. Above all, no overt adverse effects were observed in rats received PVP-VS. These results demonstrate the potential of IM VS gene delivery for CNV treatment...
  8. doi request reprint Systemic pro-opiomelanocortin expression induces melanogenic differentiation and inhibits tumor angiogenesis in established mouse melanoma
    Guei Sheung Liu
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan
    Hum Gene Ther 22:325-35. 2011
    ..In summary, systemic POMC therapy suppresses melanoma growth via induction of melanogenic differentiation and angiogenesis blockade, thereby demonstrating its potential as a novel treatment modality for melanoma...
  9. doi request reprint Tumorigenesis and prognostic role of hepatoma-derived growth factor in human gliomas
    Shu Shong Hsu
    Division of Neurosurgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC
    J Neurooncol 107:101-9. 2012
    ..We conclude that HDGF is a mitogenic growth factor in glioma progression and can be a useful prognostic marker for GBM and therapeutic target for clinical management of glioma in the future...
  10. ncbi request reprint Gene delivery of endothelial nitric oxide synthase into nucleus tractus solitarii induces biphasic response in cardiovascular functions of hypertensive rats
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Am J Hypertens 17:63-70. 2004
    ..This study was aimed to investigate the effect of endothelial NO synthase (eNOS) gene delivery in the nucleus tractus solitarii (NTS) on the cardiovascular functions of SHR...
  11. ncbi request reprint The abnormalities in the p53/p21WAF1 pathway have a significant role in the pathogenesis and progression of gastrointestinal stromal tumors
    Yeh Pin Chou
    Division of Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Niao Sung Hsiang, Kaohsiung Hsien 833, Kaohsiung, Taiwan
    Oncol Rep 19:49-56. 2008
    ..Abnormalities of the p53/p21WAF1 pathway lead to increased proliferating states, thereby triggering the progression of GISTs...
  12. doi request reprint Hepatoma-derived growth factor stimulates podosome rosettes formation in NIH/3T3 cells through the activation of phosphatidylinositol 3-kinase/Akt pathway
    Mei Lang Kung
    Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan, ROC
    Biochem Biophys Res Commun 425:169-76. 2012
    ..In summary, HDGF elicits the activation of PI3K/Akt signaling cascade, thereby promoting cytoskeleton remodeling to stimulate cellular migration...
  13. ncbi request reprint Hepatoma-derived growth factor is a novel prognostic factor for gastrointestinal stromal tumors
    Kuo Chin Chang
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Int J Cancer 121:1059-65. 2007
    ..We conclude that HDGF is a novel prognostic factor for GIST patients...
  14. doi request reprint Downregulation of hepatoma-derived growth factor contributes to retarded lung metastasis via inhibition of epithelial-mesenchymal transition by systemic POMC gene delivery in melanoma
    Han En Tsai
    Institute of Biomedical Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
    Mol Cancer Ther 12:1016-25. 2013
    ..Together, these results indicate that HDGF downregulation participates in POMC-induced suppression of metastasis and EMT in melanoma...
  15. doi request reprint Hepatoma-derived growth factor regulates breast cancer cell invasion by modulating epithelial--mesenchymal transition
    San Cher Chen
    Institute of Biomedical Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
    J Pathol 228:158-69. 2012
    ..HDGF over-expression may exert a prognostic role for tumour metastasis and recurrence in breast cancer by modulating EMT. Copyright © 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd...
  16. doi request reprint Pro-opiomelanocortin gene delivery suppresses the growth of established Lewis lung carcinoma through a melanocortin-1 receptor-independent pathway
    Han En Tsai
    Institute of Biomedical Science, National Sun Yat Sen University, Kaohsiung, Taiwan
    J Gene Med 14:44-53. 2012
    ..Our previous studies have indicated that POMC gene delivery inhibited the progression and metastasis of B16-F10 melanoma via the α- melanocyte-stimulating hormone/melanortin-1 receptor (MC-1R) pathway...
  17. pmc Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells
    Jiin Haur Chuang
    Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung 804, Taiwan
    J Biomed Sci 18:65. 2011
    ..However, it remains unknown whether TLR3 may serve as a therapeutic target in human neuroblastoma (NB)...
  18. doi request reprint Overexpression of VEGF is associated with positive p53 immunostaining in hepatocellular carcinoma (HCC) and adverse outcome of HCC patients
    Po Lin Tseng
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Surg Oncol 98:349-57. 2008
    ....
  19. doi request reprint Glial cell line-derived neurotrophic factor gene transfer exerts protective effect on axons in sciatic nerve following constriction-induced peripheral nerve injury
    Jhih Yin Shi
    Institute of Biological Sciences, National Sun Yat Sen University, Kaohsiung 804, Taiwan
    Hum Gene Ther 22:721-31. 2011
    ....
  20. ncbi request reprint Increased endostatin/collagen XVIII expression correlates with elevated VEGF level and poor prognosis in hepatocellular carcinoma
    Tsung Hui Hu
    Division of Hepatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Mod Pathol 18:663-72. 2005
    ..034) by multivariate analysis. In conclusion, increased endostatin/collagen XVIII expression correlated with hepatoma progression and predicted poor prognosis for patients with hepatocellular carcinoma...
  21. ncbi request reprint Induction of apoptosis in rabbit oral mucosa by 1.23% acidulated phosphate fluoride gel
    Chia Ling Tsai
    Department of Pediatric Dentistry, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Arch Toxicol 82:81-7. 2008
    ..The results demonstrate in vivo that 1.23% APF induced apoptosis in basal epithelial cells of rabbit oral mucosa. It suggests the possible necessity to prevent oral mucosa contact when APF applied on teeth...
  22. doi request reprint PTEN overexpression attenuates angiogenic processes of endothelial cells by blockade of endothelin-1/endothelin B receptor signaling
    Hsiao Mei Kuo
    Department of Biological Sciences, National Sun Yat Sen University, 70 Lien Hai Rd, Kaohsiung 804, Taiwan
    Atherosclerosis 221:341-9. 2012
    ..In summary, PTEN upregulation induces endothelial dysfunction by attenuating the availability and signaling of multiple angiogenic pathways in endothelial cells, thereby may contribute to thrombosis of AV graft...
  23. ncbi request reprint Dehydrated form of plasmid expressing basic fibroblast growth factor-polyethylenimine complex is a novel and accurate method for gene transfer to the cornea
    Chien Neng Kuo
    Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan, Republic of China
    Curr Eye Res 30:1015-24. 2005
    ..We describe a novel vector system of nonviral gene transfer into the cornea using a dehydrated form of a plasmid expressing basic fibroblast growth factor-polyethylenimine (p-bFGF-PEI) complex to induce angiogenesis...
  24. ncbi request reprint Modulation of angiogenic processes in cultured endothelial cells by low density lipoproteins subfractions from patients with familial hypercholesterolemia
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan
    Atherosclerosis 186:448-57. 2006
    ..To continue our study of homozygotic familial hypercholesterolemic (FH)-LDL, we report the effects of FH-LDL subfractions (FH-L1 to FH-L5) on the angiogenic processes in cultured endothelial cells...
  25. pmc Rapid induction of orthotopic hepatocellular carcinoma in immune-competent rats by non-invasive ultrasound-guided cells implantation
    Hoi Hung Chan
    Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
    BMC Gastroenterol 10:83. 2010
    ..This was done by ultrasound-guided implantation of cancer cells and the model was used to evaluate the therapeutic efficacy of short-term and low-dose epirubicin chemotherapy...
  26. pmc Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN
    Tian Huei Chu
    Institute of Biomedical Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
    Oncotarget 5:1475-90. 2014
    ..PTEN gene delivery by adenovirus reduced CD44/CD133 expression in vitro and hepatoma formation in vivo. This study suggests that celecoxib suppresses cancer stemness and progression of HCC via activation of PPARγ/PTEN signaling. ..
  27. ncbi request reprint Development of a universal anti-polyethylene glycol reporter gene for noninvasive imaging of PEGylated probes
    Kuo Hsiang Chuang
    Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Nucl Med 51:933-41. 2010
    ..In this study, we constructed a versatile and nonimmunogenic reporter gene to noninvasively image gene expression or cell delivery by optical imaging, MRI, and small-animal PET...
  28. ncbi request reprint Increased superoxide anion in rostral ventrolateral medulla contributes to hypertension in spontaneously hypertensive rats via interactions with nitric oxide
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, 386, Ta Chung 1st Road, Kaohsiung, 813, Taiwan, Republic of China
    Free Radic Biol Med 38:450-62. 2005
    ..We conclude that an elevated level of O2*- in the RVLM is associated with hypertension in SHR. More importantly, this elevated O2*- may contribute to hypertension by reducing the NO-promoted cardiovascular depression...
  29. ncbi request reprint Blockade of endothelin-1 release contributes to the anti-angiogenic effect by pro-opiomelanocortin overexpression in endothelial cells
    Hing Chung Lam
    Division of Medical Research, Department of Medical Education and Research, Kaohsiung Veterans General Hospital, 386, Ta chung 1st Rd, Kaohsiung, Taiwan 813, Republic of China
    Exp Biol Med (Maywood) 231:782-8. 2006
    ..05). In summary, the attenuated ET-1 release and angiogenic processes by POMC overexpression may contribute to endothelial dysfunction, thereby providing a link between Cushing's syndrome and cardiovascular diseases...
  30. doi request reprint Prophylactic proopiomelanocortin expression alleviates capsaicin-induced neurogenic inflammation in rat trachea
    Guei Sheung Liu
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Shock 32:645-50. 2009
    ..The present study indicates that the anti-inflammatory POMC gene vector or melanocortins may constitute a therapeutic alternative for neurogenic inflammation...
  31. doi request reprint Upregulation of hepatoma-derived growth factor is involved in murine hepatic fibrogenesis
    Ying Hsien Kao
    Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung 804, Taiwan
    J Hepatol 52:96-105. 2010
    ....
  32. doi request reprint Cyclin-dependent kinase inhibitor roscovitine induces cell cycle arrest and apoptosis in rabbit retinal pigment epithelial cells
    Pei Chang Wu
    Department of Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung Hsien, Taiwan
    J Ocul Pharmacol Ther 24:25-33. 2008
    ..This in vitro study investigated the antiproliferative and apoptotic effects of roscovitine in cultured rabbit retinal pigment epithelial (RPE) cells...
  33. doi request reprint The expression and prognostic role of hepatoma-derived growth factor in colorectal stromal tumors
    Tsung Hui Hu
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Dis Colon Rectum 52:319-26. 2009
    ..This study investigated the expression and prognostic role of hepatoma-derived growth factor (HDGF) in colorectal stromal tumor...
  34. ncbi request reprint Gene transfer of glial cell line-derived neurotrophic factor promotes functional recovery following spinal cord contusion
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Exp Neurol 183:508-15. 2003
    ..This research should provide information for developing a clinical strategy for GDNF gene therapy...
  35. pmc Biphasic response of mitochondrial biogenesis to oxidative stress in visceral fat of diet-induced obesity mice
    Pei Wen Wang
    1 Department of Internal Medicine, Chang Gung University College of Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Antioxid Redox Signal 20:2572-88. 2014
    ..Innovation and Conclusion: These data suggest that IR and ROS production occur before the biphasic changes of mitochondrial biogenesis in AT, and the VF plays a more crucial role. Antioxid. Redox Signal. 20, 2572-2588. ..
  36. ncbi request reprint The effects of different doses of atorvastatin on plasma endothelin-1 levels in type 2 diabetic patients with dyslipidemia
    Hing Chung Lam
    Division of Medical Research, Department of Medical Education and Research, Kaohsiung Veterans General Hospital, 386, Ta chung 1st Rd, Kaohsiung, Taiwan 813, Republic of China
    Exp Biol Med (Maywood) 231:1010-5. 2006
    ..The clinical significance of these biphasic lipid-independent statin effects is unknown and the present study suggests that 20 mg atorvastatin may have the best benefits in treating diabetic patients with dyslipidemia...
  37. ncbi request reprint Differential expression of delta-like gene and protein in neuroblastoma, ganglioneuroblastoma and ganglioneuroma
    Chih Cheng Hsiao
    Department of Pediatrics, Division of Hematology Oncology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Mod Pathol 18:656-62. 2005
    ..Furthermore, higher dlk protein expression in the tumor endothelium than in the endothelium of normal adrenal gland implies that dlk may regulate the endothelial function in neuroblastic tumors...
  38. ncbi request reprint 2-Deoxyglucose treatment complements the cisplatin- or BH3-only mimetic-induced suppression of neuroblastoma cell growth
    Jiin Haur Chuang
    The Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Int J Biochem Cell Biol 45:944-51. 2013
    ..In conclusion, the glycolytic inhibitor 2DG complemented the cisplatin- or ABT737-induced suppression of growth in NB cells, which are sensitive to glycolytic inhibition...
  39. ncbi request reprint Tumor necrosis factor-beta +252A polymorphism is associated with systemic lupus erythematosus in Taiwan
    Ling Ying Lu
    Division of Allergy, Immunology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    J Formos Med Assoc 104:563-70. 2005
    ..The cytokines investigated included tumor necrosis factor-alpha (TNF-alpha), TNF-beta (TNF-beta), interleukin (IL)-4, IL-10 and transforming growth factor-beta1 (TGF-beta1)...
  40. ncbi request reprint Expression of hepatoma-derived growth factor in hepatocellular carcinoma
    Tsung Hui Hu
    Division of Hepatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Cancer 98:1444-56. 2003
    ..Hepatoma-derived growth factor (HDGF) is a novel growth factor derived from a hepatoma cell line. The current study was designed to elucidate the role of HDGF expression during the pathogenesis of hepatocellular carcinoma (HCC)...
  41. ncbi request reprint Antinociceptive potentiation and attenuation of tolerance by intrathecal electric stimulation in rats
    Chung Ren Lin
    Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
    Anesth Analg 96:1711-6, table of contents. 2003
    ..Increases in spinal glycine release may be the underlying mechanism. This method may merit further investigation in the context of the long-term use of intrathecal opioids for controlling chronic pain...
  42. doi request reprint Piperazine-designed alpha 1A/alpha 1D-adrenoceptor blocker KMUP-1 and doxazosin provide down-regulation of androgen receptor and PSA in prostatic LNCaP cells growth and specifically in xenografts
    Chi Ming Liu
    Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Prostate 69:610-23. 2009
    ..This study is aimed to further investigate whether KMUP-1 and doxazosin prevent from prostate cancer cell growth via androgen-dependent and -independent pathway in vivo and in vitro...
  43. doi request reprint Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan
    Gau Tyan Lin
    Department of Orthopedic Surgery, Kaohsiung Medical University, Chung Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    OMICS 13:165-72. 2009
    ....
  44. ncbi request reprint Role of nitric oxide in alpha-melanocyte-stimulating hormone-induced hypotension in the nucleus tractus solitarii of the spontaneously hypertensive rats
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, and Graduate Institute of Biochemistry, Kaohsiung Medical University, 386 Ta Chung 1st Road, Kaohsiung 813, Taiwan
    J Pharmacol Exp Ther 321:455-61. 2007
    ..In summary, intra-NTS injection of alpha-MSH induces hypotension and bradycardia of SHR via MC-4R signaling, which activates cAMP/PKA and iNOS...
  45. doi request reprint Topical bevacizumab eyedrops for limbal-conjunctival neovascularization in impending recurrent pterygium
    Pei Chang Wu
    Department of Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Cornea 28:103-4. 2009
    ..To report a case of impending recurrent pterygium treated with topical bevacizumab eyedrops...
  46. ncbi request reprint Elevated serum anti-endothelial cell autoantibodies titer is associated with lupus nephritis in patients with systemic lupus erythematosus
    Jui Cheng Tseng
    Division of Allergy, Immunology, and Rheumatology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    J Microbiol Immunol Infect 40:50-5. 2007
    ..However, the association between endothelial dysfunction and renal manifestations remains unclear in Taiwanese SLE patients...
  47. pmc Functional production of a soluble and secreted single-chain antibody by a bacterial secretion system
    Chiu Min Cheng
    Department of Aquaculture, National Kaohsiung Marine University, Kaohsiung, Taiwan
    PLoS ONE 9:e97367. 2014
    ....
  48. ncbi request reprint Characterization of the rat A2A adenosine receptor gene: a 4.8-kb promoter-proximal DNA fragment confers selective expression in the central nervous system
    Yi Chao Lee
    Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan
    Eur J Neurosci 18:1786-96. 2003
    ..Furthermore, expressions of A2A-R and the transgene were found in both neurons and astrocytes, suggesting that adenosine might mediate its function through A2A-R in both cell types...
  49. pmc Adenoviral-mediated glial cell line-derived neurotrophic factor gene transfer has a protective effect on sciatic nerve following constriction-induced spinal cord injury
    An Kuo Chou
    Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, R O C
    PLoS ONE 9:e92264. 2014
    ..GDNF could be a good therapeutic tool to attenuate programmed cell death, including apoptosis and autophagy, consequent to CCI-induced peripheral nerve injury. ..
  50. doi request reprint Heat shock protein 60 protects skeletal tissue against glucocorticoid-induced bone mass loss by regulating osteoblast survival
    Feng Sheng Wang
    Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Bone 49:1080-9. 2011
    ..Enhancement of HSP60 function is beneficial for protecting bone tissue against the glucocorticoid-induced inhibition of bone cell viability and bone formation...