Kwok Keung Tai

Summary

Publications

  1. ncbi request reprint Activation of adenosine triphosphate-sensitive potassium channels confers protection against rotenone-induced cell death: therapeutic implications for Parkinson's disease
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Institute, Long Beach Memorial Medical Center, California 90806, USA
    J Neurosci Res 69:559-66. 2002
  2. doi request reprint Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2801 Atlantic Ave, Long Beach, CA, USA
    Neurotox Res 20:321-8. 2011
  3. doi request reprint (-)-Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, reduces dichlorodiphenyl-trichloroethane (DDT)-induced cell death in dopaminergic SHSY-5Y cells
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2801 Atlantic Ave, Long Beach, CA 90806, USA
    Neurosci Lett 482:183-7. 2010
  4. doi request reprint Memantine exacerbates myoclonic jerks in a rat model of posthypoxic myoclonus
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2801 Atlantic Ave, Long Beach, CA 90801, USA
    Brain Res 1343:194-8. 2010
  5. doi request reprint Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration
    K K Tai
    Long Beach Memorial Medical Center, Long Beach, CA 90806, USA
    Brain Inj 23:1081-8. 2009
  6. doi request reprint Ketogenic diet prevents cardiac arrest-induced cerebral ischemic neurodegeneration
    K K Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2625 Pasadena Ave, Long Beach, CA, USA
    J Neural Transm 115:1011-7. 2008
  7. ncbi request reprint Ketogenic diet prevents seizure and reduces myoclonic jerks in rats with cardiac arrest-induced cerebral hypoxia
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2625 Pasadena Ave, Long Beach, CA 90806, USA
    Neurosci Lett 425:34-8. 2007
  8. ncbi request reprint Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus
    K K Tai
    Long Beach Memorial Medical Center, The Parkinson s and Movement Disorder Research Laboratory, Long Beach, California 90806, USA
    J Neural Transm 114:1547-51. 2007
  9. ncbi request reprint NMDA receptor-mediated excitotoxicity contributes to the cerebral hypoxic injury of a rat model of posthypoxic myoclonus
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, Long Beach, CA 90806, USA
    Brain Res 1133:209-15. 2007
  10. ncbi request reprint Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Institute, Long Beach Memorial Medical Center, 2625 Pasadena Avenue, Long Beach, CA 90806, USA
    J Neurochem 84:1193-200. 2003

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Activation of adenosine triphosphate-sensitive potassium channels confers protection against rotenone-induced cell death: therapeutic implications for Parkinson's disease
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Institute, Long Beach Memorial Medical Center, California 90806, USA
    J Neurosci Res 69:559-66. 2002
    ....
  2. doi request reprint Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2801 Atlantic Ave, Long Beach, CA, USA
    Neurotox Res 20:321-8. 2011
    ..In conclusion, our results suggest that antioxidant idebenone induced apoptosis when used in high concentrations...
  3. doi request reprint (-)-Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, reduces dichlorodiphenyl-trichloroethane (DDT)-induced cell death in dopaminergic SHSY-5Y cells
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2801 Atlantic Ave, Long Beach, CA 90806, USA
    Neurosci Lett 482:183-7. 2010
    ....
  4. doi request reprint Memantine exacerbates myoclonic jerks in a rat model of posthypoxic myoclonus
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2801 Atlantic Ave, Long Beach, CA 90801, USA
    Brain Res 1343:194-8. 2010
    ..Further, these results also suggest that NMDA receptor antagonists would exacerbate posthypoxic myoclonus in this animal model...
  5. doi request reprint Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration
    K K Tai
    Long Beach Memorial Medical Center, Long Beach, CA 90806, USA
    Brain Inj 23:1081-8. 2009
    ..To investigate the role of ATP-sensitive potassium (K(ATP)) channels in the neuroprotective effects of a ketogenic diet against cardiac arrest-induced cerebral ischemic brain injury-induced neurodegeneration...
  6. doi request reprint Ketogenic diet prevents cardiac arrest-induced cerebral ischemic neurodegeneration
    K K Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2625 Pasadena Ave, Long Beach, CA, USA
    J Neural Transm 115:1011-7. 2008
    ..The results demonstrate that KD can prevent cardiac arrest-induced cerebral ischemic neurodegeneration in selected brain regions...
  7. ncbi request reprint Ketogenic diet prevents seizure and reduces myoclonic jerks in rats with cardiac arrest-induced cerebral hypoxia
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, 2625 Pasadena Ave, Long Beach, CA 90806, USA
    Neurosci Lett 425:34-8. 2007
    ..The results suggested that the KD has beneficial effects against posthypoxic seizure and myoclonus...
  8. ncbi request reprint Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus
    K K Tai
    Long Beach Memorial Medical Center, The Parkinson s and Movement Disorder Research Laboratory, Long Beach, California 90806, USA
    J Neural Transm 114:1547-51. 2007
    ..These findings demonstrate that brivaracetam possesses more potent anti-seizure and anti-myoclonic activity than levetiracetam in an established rat model of cardiac arrest-induced post-hypoxic myoclonus...
  9. ncbi request reprint NMDA receptor-mediated excitotoxicity contributes to the cerebral hypoxic injury of a rat model of posthypoxic myoclonus
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, Long Beach, CA 90806, USA
    Brain Res 1133:209-15. 2007
    ..The results suggest that the neurodegeneration observed in specific areas of the brain of the posthypoxic rats is contributed by NMDA receptor-mediated excitotoxicity...
  10. ncbi request reprint Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Institute, Long Beach Memorial Medical Center, 2625 Pasadena Avenue, Long Beach, CA 90806, USA
    J Neurochem 84:1193-200. 2003
    ..Taken together, our results demonstrate for the first time that activation of mitochondrial KATP channels elicits protection against rotenone-induced cell death...
  11. pmc Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, Long Beach, California, United States of America
    PLoS ONE 8:e60309. 2013
    ..These results suggest that acid-sensing ion channels play a more pivotal role than N-methyl-D-aspartate receptors in mediating cerebral hypoxia-induced brain injury during ischemic insult...
  12. ncbi request reprint Post-hypoxic animal model of myoclonus
    Kwok Keung Tai
    The Parkinson s and Movement Disorders Research Laboratory, Long Beach Memorial Medical Center, Long Beach, CA 90806, USA
    Parkinsonism Relat Disord 13:377-81. 2007
    ..Therapy developed for myoclonus in this model may be helpful for myoclonus from other etiologies such as corticobasal degeneration, Lewy-body disorders, Creutzfeld-Jacob disease, Alzheimer's disease...
  13. ncbi request reprint Post-hypoxic myoclonus induces Fos expression in the reticular thalamic nucleus and neurons in the brainstem
    Kwok Keung Tai
    The Parkinson s and Movement Disorder Research Laboratory, Long Beach Memorial Medical Center, CA 90806, USA
    Brain Res 1059:122-8. 2005
    ..The results suggest that neuronal activity in the RT and the MLF plays a contributing role in post-hypoxic myoclonus...
  14. ncbi request reprint Ion channels as a target for drug design
    Kwok Keung Tai
    Curr Pharm Des 13:3168. 2007
  15. pmc Interaction of KCNE subunits with the KCNQ1 K+ channel pore
    Gianina Panaghie
    Greenberg Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, 520 East 70th Street, New York, NY 10021, USA
    J Physiol 570:455-67. 2006
    ..Further, the results suggest specifically that two of the interactions, MiRP2-72/KCNQ1-338 and MinK-58/KCNQ1-340, are required for the contrasting gating effects of MinK and MiRP2...