Michael Synowitz

Summary

Publications

  1. ncbi request reprint Case history: multicentric glioma with involvement of the optic chiasm
    Michael Synowitz
    Department of Neurosurgery, Helios Hospital Berlin, Hospital Buch, Hobrechtsfelder Chaussee 96, 13122 Berlin Buch, Germany
    Clin Neurol Neurosurg 105:66-8. 2002
  2. doi request reprint Expression of glucose transporter 1 is associated with loss of heterozygosity of chromosome 1p in oligodendroglial tumors WHO grade II
    Florian Stockhammer
    Department of Neurosurgery, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    J Mol Histol 39:553-60. 2008
  3. ncbi request reprint Tumor Young Investigator Award: tropism and antitumorigenic effect of endogenous neural precursors for gliomas
    Michael Synowitz
    Department of Neurosurgery, HELIOS Hospital, Berlin, Germany
    Clin Neurosurg 53:336-44. 2006
  4. ncbi request reprint [Planning for brain surgery in brain tumors]
    Dirk Labudde
    Universitat Rostock
    Z Med Phys 12:182-90. 2002
  5. ncbi request reprint Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival
    Rainer Glass
    Cellular Neuroscience Group, Max Delbruck Center for Molecular Medicine, 13092 Berlin, Germany
    J Neurosci 25:2637-46. 2005
  6. ncbi request reprint Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2
    Darko S Markovic
    Cellular Neuroscience Group, Max Delbrück Center for Molecular Medicine MDC, Berlin, Germany
    J Neuropathol Exp Neurol 64:754-62. 2005
  7. ncbi request reprint A1 adenosine receptors in microglia control glioblastoma-host interaction
    Michael Synowitz
    Cellular Neuroscience Group, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Cancer Res 66:8550-7. 2006
  8. ncbi request reprint The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A
    Marcin Sliwa
    Laboratory of Transcription Regulation, Department of Cell Biology, Nencki Institute of Experimental Biology, Warsaw, Poland
    Brain 130:476-89. 2007

Collaborators

  • Helmut Kettenmann
  • Andreas von Deimling
  • Florian Stockhammer
  • Rainer Glass
  • Darko S Markovic
  • Marcin Sliwa
  • Dirk Labudde
  • Konrad Gabrusiewicz
  • Bozena Kaminska
  • Darko Markovic
  • Aleksandra Wesolowska
  • Malgorzata Zawadzka
  • Golo Kronenberg
  • Nico Van Rooijen
  • Gerd Kempermann
  • Li Ping Wang
  • Jürgen Kiwit
  • Daniela Gast
  • Joo Hee Walzlein
  • Sven Hartmann

Detail Information

Publications8

  1. ncbi request reprint Case history: multicentric glioma with involvement of the optic chiasm
    Michael Synowitz
    Department of Neurosurgery, Helios Hospital Berlin, Hospital Buch, Hobrechtsfelder Chaussee 96, 13122 Berlin Buch, Germany
    Clin Neurol Neurosurg 105:66-8. 2002
    ..The patient had a complete prostatectomy of adenocarcinoma a year before. The coincidence of multicentric gliomas and prostate cancer is briefly discussed...
  2. doi request reprint Expression of glucose transporter 1 is associated with loss of heterozygosity of chromosome 1p in oligodendroglial tumors WHO grade II
    Florian Stockhammer
    Department of Neurosurgery, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    J Mol Histol 39:553-60. 2008
    ..Conclusion Expression of GLUT-1 is significantly reduced in low-grade oligodendroglial tumors harboring LOH 1p. Further studies should address the functional role of GLUT-1 in regard to chemosensitivity of oligodendrogliomas...
  3. ncbi request reprint Tumor Young Investigator Award: tropism and antitumorigenic effect of endogenous neural precursors for gliomas
    Michael Synowitz
    Department of Neurosurgery, HELIOS Hospital, Berlin, Germany
    Clin Neurosurg 53:336-44. 2006
  4. ncbi request reprint [Planning for brain surgery in brain tumors]
    Dirk Labudde
    Universitat Rostock
    Z Med Phys 12:182-90. 2002
    ..The aim of the proposed model is, as further step, the integration and adaptation in apposite software solutions for the stereotactic orientation in the CNS...
  5. ncbi request reprint Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival
    Rainer Glass
    Cellular Neuroscience Group, Max Delbruck Center for Molecular Medicine, 13092 Berlin, Germany
    J Neurosci 25:2637-46. 2005
    ..Our results indicate that tumor cells attract endogenous precursor cells; the presence of precursor cells is antitumorigenic; and this cellular interaction decreases with aging...
  6. ncbi request reprint Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2
    Darko S Markovic
    Cellular Neuroscience Group, Max Delbrück Center for Molecular Medicine MDC, Berlin, Germany
    J Neuropathol Exp Neurol 64:754-62. 2005
    ..Our data indicate that glioma cells stimulate microglial cells to increase breakdown of extracellular matrix and thereby promote tumor invasiveness...
  7. ncbi request reprint A1 adenosine receptors in microglia control glioblastoma-host interaction
    Michael Synowitz
    Cellular Neuroscience Group, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Cancer Res 66:8550-7. 2006
    ..A(1)AR agonists suppressed tumor growth. When, however, microglial cells were depleted from the slices, the agonists even stimulated tumor growth. Thus, adenosine attenuates glioblastoma growth acting via A(1)AR in microglia...
  8. ncbi request reprint The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A
    Marcin Sliwa
    Laboratory of Transcription Regulation, Department of Cell Biology, Nencki Institute of Experimental Biology, Warsaw, Poland
    Brain 130:476-89. 2007
    ..Our findings that CsA interferes at clinically relevant concentrations with the tumour-promoting role of microglia and impairs invasive growth of glioma cells in vivo may provide a novel therapeutic strategy against gliomas...