Brian G Williams

Summary

Affiliation: World Health Organization
Country: Switzerland

Publications

  1. pmc Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence
    Catherine R Stevenson
    Medical Research Council Epidemiology Unit, Cambridge, UK
    BMC Public Health 7:234. 2007
  2. pmc Cost, affordability and cost-effectiveness of strategies to control tuberculosis in countries with high HIV prevalence
    Christine S M Currie
    School of Mathematics, University of Southampton, Southampton, SO17 1BJ, UK
    BMC Public Health 5:130. 2005
  3. pmc The potential impact of male circumcision on HIV in Sub-Saharan Africa
    Brian G Williams
    World Health Organization, Stop TB Department, Geneva, Switzerland
    PLoS Med 3:e262. 2006
  4. ncbi request reprint HIV infection, antiretroviral therapy, and CD4+ cell count distributions in African populations
    Brian G Williams
    Stop TB Department, World Health Organization, Geneva 1211 CH 1211, Switzerland
    J Infect Dis 194:1450-8. 2006
  5. ncbi request reprint The design effect and cluster samples: optimising tuberculosis prevalence surveys
    B Williams
    World Health Organization, Geneva, Switzerland
    Int J Tuberc Lung Dis 12:1110-5. 2008
  6. ncbi request reprint Changing patterns of knowledge, reported behaviour and sexually transmitted infections in a South African gold mining community
    Brian G Williams
    16 rue de la Canonniere, Geneva 1202, Switzerland
    AIDS 17:2099-107. 2003
  7. ncbi request reprint Antiretroviral drugs for tuberculosis control in the era of HIV/AIDS
    Brian G Williams
    Communicable Diseases, World Health Organization, 1211 Geneva 27, Switzerland
    Science 301:1535-7. 2003
  8. ncbi request reprint Estimates of world-wide distribution of child deaths from acute respiratory infections
    Brian G Williams
    World Health Organization, 20 Avenue Appia, Geneva 27, CH 1211, Switzerland
    Lancet Infect Dis 2:25-32. 2002
  9. ncbi request reprint The population dynamics and control of tuberculosis
    Christopher Dye
    World Health Organization, CH1211 Geneva 27, Switzerland
    Science 328:856-61. 2010
  10. pmc Malaria attributable to the HIV-1 epidemic, sub-Saharan Africa
    Eline L Korenromp
    World Health Organization, Geneva, Switzerland
    Emerg Infect Dis 11:1410-9. 2005

Detail Information

Publications40

  1. pmc Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence
    Catherine R Stevenson
    Medical Research Council Epidemiology Unit, Cambridge, UK
    BMC Public Health 7:234. 2007
    ..Diabetes increases the risk of TB. Our aim was to assess the potential impact of diabetes as a risk factor for incident pulmonary tuberculosis, using India as an example...
  2. pmc Cost, affordability and cost-effectiveness of strategies to control tuberculosis in countries with high HIV prevalence
    Christine S M Currie
    School of Mathematics, University of Southampton, Southampton, SO17 1BJ, UK
    BMC Public Health 5:130. 2005
    ..However, published cost and cost-effectiveness studies are limited...
  3. pmc The potential impact of male circumcision on HIV in Sub-Saharan Africa
    Brian G Williams
    World Health Organization, Stop TB Department, Geneva, Switzerland
    PLoS Med 3:e262. 2006
    ..We explore the implications of this finding for the promotion of MC as a public health intervention to control HIV in sub-Saharan Africa...
  4. ncbi request reprint HIV infection, antiretroviral therapy, and CD4+ cell count distributions in African populations
    Brian G Williams
    Stop TB Department, World Health Organization, Geneva 1211 CH 1211, Switzerland
    J Infect Dis 194:1450-8. 2006
    ....
  5. ncbi request reprint The design effect and cluster samples: optimising tuberculosis prevalence surveys
    B Williams
    World Health Organization, Geneva, Switzerland
    Int J Tuberc Lung Dis 12:1110-5. 2008
    ..We illustrate the results using data from a recent survey in Cambodia in which TB was diagnosed using sputum smears, cultures and X-rays...
  6. ncbi request reprint Changing patterns of knowledge, reported behaviour and sexually transmitted infections in a South African gold mining community
    Brian G Williams
    16 rue de la Canonniere, Geneva 1202, Switzerland
    AIDS 17:2099-107. 2003
    ..This included community-based peer education, condom distribution, syndromic management of sexually transmitted infections (STI), and presumptive STI treatment for sex workers...
  7. ncbi request reprint Antiretroviral drugs for tuberculosis control in the era of HIV/AIDS
    Brian G Williams
    Communicable Diseases, World Health Organization, 1211 Geneva 27, Switzerland
    Science 301:1535-7. 2003
    ..However, ARV drugs could enhance the treatment of TB, and TB programs provide an important entry point for the treatment of HIV/AIDS...
  8. ncbi request reprint Estimates of world-wide distribution of child deaths from acute respiratory infections
    Brian G Williams
    World Health Organization, 20 Avenue Appia, Geneva 27, CH 1211, Switzerland
    Lancet Infect Dis 2:25-32. 2002
    ..This analysis suggests that throughout the world 1.9 million (95% CI 1.6-2.2 million) children died from ARI in 2000, 70% of them in Africa and southeast Asia...
  9. ncbi request reprint The population dynamics and control of tuberculosis
    Christopher Dye
    World Health Organization, CH1211 Geneva 27, Switzerland
    Science 328:856-61. 2010
    ..Whatever the technology used, success depends critically on the social, institutional, and epidemiological context in which it is applied...
  10. pmc Malaria attributable to the HIV-1 epidemic, sub-Saharan Africa
    Eline L Korenromp
    World Health Organization, Geneva, Switzerland
    Emerg Infect Dis 11:1410-9. 2005
    ..These effects were due to high HIV-1 prevalence in rural areas and the locally unstable nature of malaria transmission that results in a high proportion of adult cases...
  11. ncbi request reprint Global incidence of multidrug-resistant tuberculosis
    Matteo Zignol
    Stop TB Department, World Health Organization, Geneva 1211, Switzerland
    J Infect Dis 194:479-85. 2006
    ....
  12. ncbi request reprint Effects of human immunodeficiency virus infection on recurrence of tuberculosis after rifampin-based treatment: an analytical review
    Eline L Korenromp
    Communicable Diseases, Stop TB Department, World Health Organization, Geneva, Switzerland
    Clin Infect Dis 37:101-12. 2003
    ..025). In countries where HIV infection is endemic, TB recurrence may be reduced by administration of rifampin-based treatment for at least 6 months, in accordance with World Health Organization recommendations...
  13. doi request reprint Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model
    Reuben M Granich
    Department of HIV AIDS, WHO, Geneva, Switzerland
    Lancet 373:48-57. 2009
    ..We investigated a theoretical strategy of universal voluntary HIV testing and immediate treatment with ART, and examined the conditions under which the HIV epidemic could be driven towards elimination...
  14. ncbi request reprint Transmission of HIV-1 infection in sub-Saharan Africa and effect of elimination of unsafe injections
    George P Schmid
    WHO, Geneva, Switzerland
    Lancet 363:482-8. 2004
    ..Increased efforts are needed to reduce sexual transmission of HIV-1...
  15. ncbi request reprint What is the limit to case detection under the DOTS strategy for tuberculosis control?
    Christopher Dye
    Communicable Diseases, World Health Organization, 1211 Geneva 27, Switzerland
    Tuberculosis (Edinb) 83:35-43. 2003
    ....
  16. pmc Eliminating human tuberculosis in the twenty-first century
    Christopher Dye
    HIV AIDS, Tuberculosis and Malaria, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland
    J R Soc Interface 5:653-62. 2008
    ..Our results should be a stimulus to those who develop, manufacture and implement new technology for TB control, and to their financial donors...
  17. ncbi request reprint Erasing the world's slow stain: strategies to beat multidrug-resistant tuberculosis
    Christopher Dye
    Communicable Diseases, World Health Organization, CH 1211 Geneva 27, Switzerland
    Science 295:2042-6. 2002
    ....
  18. doi request reprint A consistent log-linear relationship between tuberculosis incidence and body mass index
    Knut Lonnroth
    World Health Organization, Stop TB Department, Geneva, Switzerland
    Int J Epidemiol 39:149-55. 2010
    ..No previous systematic review has been done to explore the consistency and establish the gradient of this apparent 'dose-response' relationship...
  19. ncbi request reprint Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy
    Eline L Korenromp
    Malaria Control Department of WHO, Geneva, Switzerland
    Lancet Infect Dis 3:349-58. 2003
    ....
  20. pmc Lives saved by tuberculosis control and prospects for achieving the 2015 global target for reducing tuberculosis mortality
    Philippe Glaziou
    World Health Organization, 20 avenue Appia 20, 1211 Geneva 27, Switzerland
    Bull World Health Organ 89:573-82. 2011
    ....
  21. pmc Antiretroviral therapy for prevention of tuberculosis in adults with HIV: a systematic review and meta-analysis
    Amitabh B Suthar
    Department of HIV AIDS, World Health Organization, Geneva, Switzerland
    PLoS Med 9:e1001270. 2012
    ..We conducted a systematic review of studies that analysed the impact of antiretroviral therapy on the incidence of tuberculosis in adults with HIV infection...
  22. ncbi request reprint Impact of malaria control on childhood anaemia in Africa -- a quantitative review
    Eline L Korenromp
    World Health Organization, Roll Back Malaria, Geneva, Switzerland
    Trop Med Int Health 9:1050-65. 2004
    ..To review the impact of malaria control on haemoglobin (Hb) distributions and anaemia prevalences in children under 5 in malaria-endemic Africa...
  23. doi request reprint Slow elimination of multidrug-resistant tuberculosis
    Christopher Dye
    Office of HIV AIDS, Tuberculosis, Malaria and Neglected Tropical Diseases, World Health Organization, CH1211 Geneva 27, Switzerland
    Sci Transl Med 1:3ra8. 2009
    ..This result applies even to countries such as Estonia and Latvia, which have exceptionally high prevalence rates of multidrug-resistant tuberculosis...
  24. doi request reprint Drivers of tuberculosis epidemics: the role of risk factors and social determinants
    Knut Lonnroth
    World Health Organization, Geneva, Switzerland
    Soc Sci Med 68:2240-6. 2009
    ..The identification of risk groups also helps to target strategies for early detection of people in need of TB treatment. More research is needed on the suitability, feasibility and cost-effectiveness of these intervention options...
  25. pmc Nutrition, diabetes and tuberculosis in the epidemiological transition
    Christopher Dye
    HIV AIDS, Tuberculosis, Malaria and Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland
    PLoS ONE 6:e21161. 2011
    ..Interactions between diabetes and BMI could help or hinder TB control in growing, aging, urbanizing populations...
  26. ncbi request reprint Worldwide incidence of multidrug-resistant tuberculosis
    Christopher Dye
    Communicable Diseases, World Health Organization, 1211 Geneva 27, Switzerland
    J Infect Dis 185:1197-202. 2002
    ..2% of all new TB cases. The analysis provides the first comprehensive set of estimates of the MDR TB burden by country and globally...
  27. pmc Expanding ART for treatment and prevention of HIV in South Africa: estimated cost and cost-effectiveness 2011-2050
    Reuben Granich
    HIV AIDS Department, World Health Organization, Geneva, Switzerland
    PLoS ONE 7:e30216. 2012
    ..Antiretroviral Treatment (ART) significantly reduces HIV transmission. We conducted a cost-effectiveness analysis of the impact of expanded ART in South Africa...
  28. pmc Alcohol use as a risk factor for tuberculosis - a systematic review
    Knut Lonnroth
    Stop TB Department, World Health Organization, Geneva, Switzerland
    BMC Public Health 8:289. 2008
    ..Nor has the strength of the association been established. The objective of this study was to systematically review the available evidence on the association between alcohol use and the risk of tuberculosis...
  29. pmc Achieving universal access for human immunodeficiency virus and tuberculosis: potential prevention impact of an integrated multi-disease prevention campaign in kenya
    Reuben Granich
    Treatment and Care Unit, Department of HIV AIDS, World Health Organization, Avenue Appia 20, 1211 Geneva, Switzerland
    AIDS Res Treat 2012:412643. 2012
    ..Community-based integrated public health campaigns could be a potential solution to reach universal access and Millennium Development Goals...
  30. ncbi request reprint The impact of migration on HIV-1 transmission in South Africa: a study of migrant and nonmigrant men and their partners
    Mark N Lurie
    South African Medical Research Council, HIV Prevention and Vaccine Research Unit, Durban, South Africa
    Sex Transm Dis 30:149-56. 2003
    ..To investigate the association between migration and HIV infection among migrant and nonmigrant men and their rural partners...
  31. ncbi request reprint High incidence of HIV-1 in South Africa using a standardized algorithm for recent HIV seroconversion
    Eleanor Gouws
    Medical Research Council, Congella, South Africa
    J Acquir Immune Defic Syndr 29:531-5. 2002
    ..The HIV-1 incidence rates provide valuable additional information indicating that new infections are continuing unabated and that the HIV-1 epidemic is still growing in rural South Africa...
  32. ncbi request reprint The growing burden of tuberculosis: global trends and interactions with the HIV epidemic
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England, UK
    Arch Intern Med 163:1009-21. 2003
    ..The increasing global burden of tuberculosis (TB) is linked to human immunodeficiency virus (HIV) infection...
  33. ncbi request reprint Who infects whom? HIV-1 concordance and discordance among migrant and non-migrant couples in South Africa
    Mark N Lurie
    South African Medical Research Council, HIV Prevention and Vaccine Research Unit, Durban, South Africa
    AIDS 17:2245-52. 2003
    ..To measure HIV-1 discordance among migrant and non-migrant men and their rural partners, and to estimate the relative risk of infection from inside versus outside primary relationships...
  34. ncbi request reprint Impact of HIV on novel therapies for tuberculosis control
    Maria S Sanchez
    Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
    AIDS 22:963-72. 2008
    ..We investigated how tuberculosis is impacted by reducing treatment duration alone or combined with enhanced case detection and/or cure under different HIV prevalence levels...
  35. pmc The effect of diagnostic delays on the drop-out rate and the total delay to diagnosis of tuberculosis
    Stephen J Millen
    DST NRF Centre of Excellence for Epidemiological Modelling and Analysis SACEMA, Stellenbosch University, Western Cape, Republic of South Africa
    PLoS ONE 3:e1933. 2008
    ..Such delays are critical as infected individuals remain untreated in the community, providing more opportunities for transmission of the disease and adversely affecting the epidemic...
  36. ncbi request reprint Response to Brown et al., 'Incident and prevalent herpes simplex virus type 2 infection increases risk of HIV acquisition among women in Uganda and Zimbabwe'
    Brian G Williams
    AIDS 21:2356-7. 2007
  37. ncbi request reprint Tuberculosis epidemics driven by HIV: is prevention better than cure?
    Christine S M Currie
    Faculty of Mathematical Studies, University of Southampton, Southampton, UK
    AIDS 17:2501-8. 2003
    ..To compare the benefits of tuberculosis (TB) treatment with TB and HIV prevention for the control of TB in regions with high HIV prevalence...
  38. ncbi request reprint Human immunodeficiency virus and the prevalence of undiagnosed tuberculosis in African gold miners
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
    Am J Respir Crit Care Med 170:673-9. 2004
    ..The difference in mean duration of smear positivity was particularly marked and, if generalizable, will have major implications for TB control prospects in high HIV prevalence areas...
  39. ncbi request reprint Diabetes and the risk of tuberculosis: a neglected threat to public health?
    Catherine R Stevenson
    Medical Research Council Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Chronic Illn 3:228-45. 2007
    ..However, this is rarely highlighted in current research or control priorities. This paper aims to evaluate the evidence for an association between these two diseases...
  40. ncbi request reprint Polymorphisms in the tumor necrosis factor-alpha gene promoter may predispose to severe silicosis in black South African miners
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Am J Respir Crit Care Med 165:690-3. 2002
    ..A predominant effect on disease severity, rather than on disease frequency, appears to be a general feature of promoter polymorphism in diseases in which TNF-alpha has a critical role...