W R J Taylor

Summary

Affiliation: World Health Organization
Country: Switzerland

Publications

  1. ncbi request reprint Malaria and the lung
    W R J Taylor
    World Health Organization TDR, Avenue Appia 20, Geneva 27, CH 1211, Switzerland
    Clin Chest Med 23:457-68. 2002
  2. ncbi request reprint Assessing the Parasight-F test in northeastern Papua, Indonesia, an area of mixed Plasmodium falciparum and Plasmodium vivax transmission
    Walter R J Taylor
    US Naval Medical Research Unit No 2, Jakarta, Indonesia
    Am J Trop Med Hyg 66:649-52. 2002
  3. pmc Tolerability of azithromycin as malaria prophylaxis in adults in northeast papua, indonesia
    Walter R Taylor
    U S Naval Medical Research Unit No 2, National Institutes of Health, Jakarta, Indonesia
    Antimicrob Agents Chemother 47:2199-203. 2003
  4. ncbi request reprint Antimalarial drug toxicity: a review
    W Robert J Taylor
    WHO Tropical Disease Research, Geneva, Switzerland
    Drug Saf 27:25-61. 2004
  5. pmc Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda
    Francesco Checchi
    Epicentre, Paris, France
    Malar J 5:59. 2006
  6. pmc Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia
    Lyda Osorio
    Internacional Centre for Medical Research and Training CIDEIM Avenida 1N 3 03, Cali, Colombia
    Malar J 6:25. 2007
  7. ncbi request reprint Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment
    Kefas Mugittu
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Trop Med Int Health 12:219-23. 2007
  8. ncbi request reprint Effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos in vitro
    Monica Longo
    Department of Preclinical Development, Nerviano Medical Sciences S r l, Viale Pasteur 10, 20014 Nerviano, Milan, Italy
    Reprod Toxicol 21:83-93. 2006
  9. pmc In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up
    Kasia Stepniewska
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Rd, Bangkok 10400, Thailand
    Antimicrob Agents Chemother 48:4271-80. 2004
  10. ncbi request reprint Artesunate plus sulfadoxine-pyrimethamine for uncomplicated malaria in Kenyan children: a randomized, double-blind, placebo-controlled trial
    Charles O Obonyo
    Centre for Vector Biology and Control, Kenya Medical Research Institute, Kisumu, Kenya
    Trans R Soc Trop Med Hyg 97:585-91. 2003

Detail Information

Publications15

  1. ncbi request reprint Malaria and the lung
    W R J Taylor
    World Health Organization TDR, Avenue Appia 20, Geneva 27, CH 1211, Switzerland
    Clin Chest Med 23:457-68. 2002
    ..More research is needed to better define and tailor treatments for malarial and nonmalarial ALI and ARDS...
  2. ncbi request reprint Assessing the Parasight-F test in northeastern Papua, Indonesia, an area of mixed Plasmodium falciparum and Plasmodium vivax transmission
    Walter R J Taylor
    US Naval Medical Research Unit No 2, Jakarta, Indonesia
    Am J Trop Med Hyg 66:649-52. 2002
    ..falciparum parasitemia in patients presenting with clinical malaria. However, the high false-positive rate on day 7 limits its use for patient follow-up...
  3. pmc Tolerability of azithromycin as malaria prophylaxis in adults in northeast papua, indonesia
    Walter R Taylor
    U S Naval Medical Research Unit No 2, National Institutes of Health, Jakarta, Indonesia
    Antimicrob Agents Chemother 47:2199-203. 2003
    ..One azithromycin recipient developed an erythematous rash. Daily azithromycin was well tolerated by these Indonesian adults during 20 weeks of treatment...
  4. ncbi request reprint Antimalarial drug toxicity: a review
    W Robert J Taylor
    WHO Tropical Disease Research, Geneva, Switzerland
    Drug Saf 27:25-61. 2004
    ..Combining an artemisinin derivative with another efficacious antimalarial drug is increasingly being viewed as the optimal therapeutic strategy for malaria...
  5. pmc Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda
    Francesco Checchi
    Epicentre, Paris, France
    Malar J 5:59. 2006
    ....
  6. pmc Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia
    Lyda Osorio
    Internacional Centre for Medical Research and Training CIDEIM Avenida 1N 3 03, Cali, Colombia
    Malar J 6:25. 2007
    ..Artemisinin-based combination therapy (ACT) is being widely promoted as a strategy to counteract the increase in Plasmodium falciparum antimalarial drug resistance...
  7. ncbi request reprint Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment
    Kefas Mugittu
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Trop Med Int Health 12:219-23. 2007
    ..2%)] and 14 [24/51 (47.1%)]. These results impact significantly on resistance monitoring and point to the value of genotyping all recurrent infections in antimalarial trials...
  8. ncbi request reprint Effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos in vitro
    Monica Longo
    Department of Preclinical Development, Nerviano Medical Sciences S r l, Viale Pasteur 10, 20014 Nerviano, Milan, Italy
    Reprod Toxicol 21:83-93. 2006
    ..Extrapolating results to pregnant women exposed in the first trimester remains difficult. Pharmacovigilance and further studies of the mechanism of damage are needed...
  9. pmc In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up
    Kasia Stepniewska
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Rd, Bangkok 10400, Thailand
    Antimicrob Agents Chemother 48:4271-80. 2004
    ..94) or if the entomological inoculation rate was known. In the assessment of drug efficacy against falciparum malaria, 28 days should be the minimum period of follow-up...
  10. ncbi request reprint Artesunate plus sulfadoxine-pyrimethamine for uncomplicated malaria in Kenyan children: a randomized, double-blind, placebo-controlled trial
    Charles O Obonyo
    Centre for Vector Biology and Control, Kenya Medical Research Institute, Kisumu, Kenya
    Trans R Soc Trop Med Hyg 97:585-91. 2003
    ..However, the high background rate of parasitological failure with SP may make this combination unsuitable for widespread use in Kenya...
  11. ncbi request reprint Efficacy of artesunate plus chloroquine for the treatment of uncomplicated malaria in children in Burkina Faso: a double-blind, randomized, controlled trial
    Sodiomon Bienvenu Sirima
    Centre National de Recherche et de Formation sur le Paludisme, Ministere de la Sante, 01 B P 2028, Ouagadougou 01, Burkina Faso
    Trans R Soc Trop Med Hyg 97:345-9. 2003
    ..Despite the beneficial effects of adding AS, the high failure rate at day 28 of CQ-AS precludes its use as the first-line regimen for treating CQ-resistant P. falciparum in Burkina Faso...
  12. ncbi request reprint Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial
    Gerardo Priotto
    Epicentre, 8 rue Saint Sabin, 75011 Paris, France
    Trans R Soc Trop Med Hyg 97:325-30. 2003
    ..Treatment efficacy improved with SPAS3 but the cure rate at day 28 was modest. The combinations were well tolerated and safe. In areas where SP resistance is prevalent other combinations should be considered...
  13. ncbi request reprint Short report: in vivo sensitivity of Plasmodium falciparum to halofantrine in southern central Vietnam
    Hanh Nhan Doan
    U S Naval Medical Research Unit No 2, Jakarta, Indonesia
    Am J Trop Med Hyg 69:553-4. 2003
    ..8-99.2%) patients were sensitive. Two patients had recurrent P. falciparum parasitemia on days 14 and 21. Halofantrine effectively treated uncomplicated P. falciparum malaria in these Vietnamese patients...
  14. ncbi request reprint Antimalarial compounds: from bench to bedside
    Piero L Olliaro
    UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    J Exp Biol 206:3753-9. 2003
    ..This review will summarise current antimalarial drug developments and outline recent clinical research that aims to bring artemisinin-based combinations to those that need them most...
  15. pmc Efficacy and safety of artesunate plus amodiaquine in routine use for the treatment of uncomplicated malaria in Casamance, southern Sénégal
    Philippe Brasseur
    UR 077, IRD, Dakar, Senegal
    Malar J 6:150. 2007
    ..There are no data on the long term use of an artemisinin combination treatment in moderate or high transmission areas of Africa...