R W Peeling

Summary

Affiliation: World Health Organization
Country: Switzerland

Publications

  1. ncbi Detection of gonococcal infection : pros and cons of a rapid test
    Peter Vickerman
    London School of Hygiene and Tropical Medicine, London, UK
    Mol Diagn 9:175-9. 2005
  2. ncbi The pathogenesis of syphilis: the Great Mimicker, revisited
    Rosanna W Peeling
    Diagnostics Research and Development, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, The World Health Organization, Geneva, Switzerland
    J Pathol 208:224-32. 2006
  3. ncbi Evaluation of rapid diagnostic tests: malaria
    David Bell
    Malaria, and other Vector borne and Parasitic Diseases, World Health Organization Regional Office for the Western Pacific, PO Box 2932, Manila, Philippines
    Nat Rev Microbiol 4:S34-8. 2006
  4. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 4:S2-6. 2006
  5. pmc Evaluation of commercially available anti-dengue virus immunoglobulin M tests
    Elizabeth A Hunsperger
    Serology Diagnostics and Viral Pathogenesis Research Section, Centers for Disease Control and Prevention, San Juan, Puerto Rico
    Emerg Infect Dis 15:436-40. 2009
  6. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 6:S2-6. 2008
  7. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 4:S2-6. 2006
  8. pmc Rapid tests for sexually transmitted infections (STIs): the way forward
    R W Peeling
    Sexually Transmitted Diseases Diagnostics Initiative SDI, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases, World Health Organization, 20 Avenue Appia, Geneva, Switzerland
    Sex Transm Infect 82:v1-6. 2006
  9. pmc Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview
    Rosanna W Peeling
    Sexually Transmitted Diseases Diagnostics Initiative SDI, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 82:439-46. 2004
  10. ncbi Syphilis
    R W Peeling
    WHO, Geneva, Switzerland
    Nat Rev Microbiol 2:448-9. 2004

Collaborators

Detail Information

Publications42

  1. ncbi Detection of gonococcal infection : pros and cons of a rapid test
    Peter Vickerman
    London School of Hygiene and Tropical Medicine, London, UK
    Mol Diagn 9:175-9. 2005
    ..Their optimal use in these settings requires the development of simpler and cheaper rapid tests...
  2. ncbi The pathogenesis of syphilis: the Great Mimicker, revisited
    Rosanna W Peeling
    Diagnostics Research and Development, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, The World Health Organization, Geneva, Switzerland
    J Pathol 208:224-32. 2006
    ..Understanding of the molecular targets of these immune responses may facilitate the development of vaccines for syphilis...
  3. ncbi Evaluation of rapid diagnostic tests: malaria
    David Bell
    Malaria, and other Vector borne and Parasitic Diseases, World Health Organization Regional Office for the Western Pacific, PO Box 2932, Manila, Philippines
    Nat Rev Microbiol 4:S34-8. 2006
  4. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 4:S2-6. 2006
    ..Misdiagnosis leading to failure to treat a serious infection or wasting expensive treatment on people who are not infected remains a serious obstacle to health...
  5. pmc Evaluation of commercially available anti-dengue virus immunoglobulin M tests
    Elizabeth A Hunsperger
    Serology Diagnostics and Viral Pathogenesis Research Section, Centers for Disease Control and Prevention, San Juan, Puerto Rico
    Emerg Infect Dis 15:436-40. 2009
    ..False-positive results were found for patients with malaria or past dengue infections. Three ELISAs showing strong agreement with reference ELISAs will be included in the World Health Organization Bulk Procurement Scheme...
  6. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 6:S2-6. 2008
    ..Misdiagnosis leading to failure to treat a serious infection or wasting expensive treatment on people who are not infected remains a serious obstacle to health...
  7. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 4:S2-6. 2006
    ..Misdiagnosis leading to failure to treat a serious infection or wasting expensive treatment on people who are not infected remains a serious obstacle to health...
  8. pmc Rapid tests for sexually transmitted infections (STIs): the way forward
    R W Peeling
    Sexually Transmitted Diseases Diagnostics Initiative SDI, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases, World Health Organization, 20 Avenue Appia, Geneva, Switzerland
    Sex Transm Infect 82:v1-6. 2006
    ....
  9. pmc Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview
    Rosanna W Peeling
    Sexually Transmitted Diseases Diagnostics Initiative SDI, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 82:439-46. 2004
    ..The development of a non-invasive rapid treponemal test that distinguishes between active and past infections remains a high priority in areas where syphilis is endemic...
  10. ncbi Syphilis
    R W Peeling
    WHO, Geneva, Switzerland
    Nat Rev Microbiol 2:448-9. 2004
  11. ncbi Why do we need quality-assured diagnostic tests for sexually transmitted infections?
    Rosanna W Peeling
    WHO TDR Sexually Transmitted Diseases Diagnostics Initiative SDI, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 4:S7-19. 2006
    ....
  12. ncbi Why do we need quality-assured diagnostic tests for sexually transmitted infections?
    Rosanna W Peeling
    WHO TDR Sexually Transmitted Diseases Diagnostics Initiative SDI, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 4:909-21. 2006
    ....
  13. ncbi A guide for diagnostic evaluations
    Rosanna W Peeling
    UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases TDR, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Nat Rev Microbiol 8:S2-6. 2010
    ..Misdiagnosis leading to failure to treat a serious infection or wasting expensive treatment on people who are not infected remains a serious obstacle to health...
  14. pmc The value of mass screening for chlamydia control in high prevalence communities
    S Hodgins
    Nunavik Board of Health, Kuujjuaq, Quebec, Canada
    Sex Transm Infect 78:i64-8. 2002
    ..trachomatis infection under these circumstances. It is particularly important to target men in settings such as this where women are routinely screened in antenatal and family planning clinics...
  15. ncbi Avoiding HIV and dying of syphilis
    Rosanna W Peeling
    Diagnostics Research and Development, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases, WHO, CH 1211 Geneva 27, Switzerland
    Lancet 364:1561-3. 2004
  16. ncbi Diagnostic tests for infectious diseases in the developing world: two sides of the coin
    Tikki Pang
    Research Policy and Cooperation, World Health Organization, Ave Appia, 1211, Geneva 27, Switzerland
    Trans R Soc Trop Med Hyg 101:856-7. 2007
    ....
  17. pmc Evaluation of a rapid point-of-care test for the detection of gonococcal infection among female sex workers in Benin
    M Alary
    Population Health Research Unit, Centre Hospitalier Affilie Universitaire De Quebec, Quebec, Canada
    Sex Transm Infect 82:v29-32. 2006
    ..To assess the validity of the PATH (Seattle, Washington, USA) GC-Check rapid test, a point-of-care immunochromatographic strip test, in the detection of gonococcal infection among female sex workers (FSWs) in Benin...
  18. ncbi Reducing the burden of HIV/AIDS in infants: the contribution of improved diagnostics
    Julia E Aledort
    RAND Corporation, 1776 Main Street, PO Box 2138, Santa Monica, California 90407 2138, USA
    Nature 444:19-28. 2006
  19. pmc Distribution study of Chlamydia trachomatis serovars among high-risk women in China performed using PCR-restriction fragment length polymorphism genotyping
    Xing Gao
    Department of STD Epidemiology, National Center for STD Control, 12 Jiangwangmiao Street, Nanjing 210042, China
    J Clin Microbiol 45:1185-9. 2007
    ..trachomatis, revealing exposure to multiple sources of infection. Although the scope for generalizations is limited by our small sample size, our results showing clinical correlations with genotypes are informative...
  20. ncbi Evaluation of diagnostic tests for infectious diseases: general principles
    Shabir Banoo
    Medicines Control Council of South Africa, Pretoria, South Africa
    Nat Rev Microbiol 4:S20-32. 2006
  21. ncbi Evaluation of rapid diagnostic tests: syphilis
    Alan Herring
    Veterinary School, University of Bristol, Langford House, Langford, North Somerset, BS40 5DN, UK
    Nat Rev Microbiol 4:S33-40. 2006
  22. ncbi Evaluation of rapid diagnostic tests: chlamydia and gonorrhoea
    Alan Herring
    Veterinary School, University of Bristol, Langford House, Langford, North Somerset, BS40 5DN, UK
    Nat Rev Microbiol 4:S41-8. 2006
  23. ncbi Reducing the burden of sexually transmitted infections in resource-limited settings: the role of improved diagnostics
    Julia E Aledort
    RAND Corporation, 1776 Main Street, PO Box 2138, Santa Monica, California 90407 2138, USA
    Nature 444:59-72. 2006
  24. ncbi Evaluation of antimicrobial resistance and treatment failures for Chlamydia trachomatis: a meeting report
    Susan A Wang
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 191:917-23. 2005
    ..Evaluating C. trachomatis clinical treatment failures, interpreting laboratory findings, and correlating the 2 clearly remain extremely challenging undertakings...
  25. ncbi School based HIV prevention in Zimbabwe: feasibility and acceptability of evaluation trials using biological outcomes
    Frances M Cowan
    Department of Sexually Transmitted Diseases, Royal Free and University College Medical School, London, UK
    AIDS 16:1673-8. 2002
    ..To determine the feasibility and acceptability of conducting a community randomized trial (CRT) of an adolescent reproductive health intervention (ARHI) using biological measures of effectiveness...
  26. ncbi Strategies for control of trachoma: observational study with quantitative PCR
    Anthony W Solomon
    London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
    Lancet 362:198-204. 2003
    ..At present, who needs to be treated is unclear. We aimed to establish the burden of ocular Chlamydia trachomatis in three trachoma-endemic communities in Tanzania and The Gambia with real-time quantitative PCR...
  27. ncbi Diagnostics for the developing world
    David Mabey
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7H, UK
    Nat Rev Microbiol 2:231-40. 2004
  28. ncbi Syphilis control--a continuing challenge
    Edward W Hook
    Department of Medicine, University of Alabama at Birmingham, USA
    N Engl J Med 351:122-4. 2004
  29. pmc Diagnosis and assessment of trachoma
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
    Clin Microbiol Rev 17:982-1011, table of contents. 2004
    ..There is an urgent need for a rapid, reliable test for C. trachomatis to assist in measuring progress towards the elimination of trachoma...
  30. ncbi Mass treatment with single-dose azithromycin for trachoma
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
    N Engl J Med 351:1962-71. 2004
    ..Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is an important cause of blindness. Current recommended dosing intervals for mass azithromycin treatment for trachoma are based on a mathematical model...
  31. ncbi Chlamydia trachomatis infection in female partners of circumcised and uncircumcised adult men
    Xavier Castellsague
    Cancer Epidemiology and Registration Unit, Institut d Investigacio Biomedica de Bellvitge, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
    Am J Epidemiol 162:907-16. 2005
    ..These findings suggest that male circumcision could reduce the risk of C. trachomatis infection in female sexual partners...
  32. ncbi Evidence for Chlamydia trachomatis as a human papillomavirus cofactor in the etiology of invasive cervical cancer in Brazil and the Philippines
    Jennifer S Smith
    International Agency for Research on Cancer, F 69372 Lyon Cedex 08, France
    J Infect Dis 185:324-31. 2002
    ..C. trachomatis infection was found to be a possible cofactor of HPV in the etiology of squamous cervical cancer, and its effect may be mediated by chronic inflammation...
  33. pmc Impact of mass distribution of azithromycin on the antibiotic susceptibilities of ocular Chlamydia trachomatis
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
    Antimicrob Agents Chemother 49:4804-6. 2005
    ..No clinically or programmatically significant increase in azithromycin or tetracycline resistance was observed...
  34. ncbi Validation of syndromic algorithm for the management of genital ulcer diseases in China
    Qian qiu Wang
    National Center for STD and Leprosy Control, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, China
    Int J STD AIDS 13:469-74. 2002
    ..1. To determine the aetiologies of genital ulcers in China. 2. To evaluate a modified WHO syndromic management algorithm for genital ulcer disease (GUD)...
  35. ncbi Evaluation of diagnostic tests for infectious diseases: general principles
    Shabir Banoo
    Nat Rev Microbiol 4:S21-31. 2006
  36. ncbi Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?
    Francois Chappuis
    Travel and Migration Medicine Unit, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Nat Rev Microbiol 5:873-82. 2007
    ..New diagnostic tools and new treatment strategies will only have an impact if they are made widely available to patients...
  37. pmc Risk factors for syphilis infection among pregnant women: results of a case-control study in Shenzhen, China
    Hua Zhou
    Institute of Dermatology, Shenzhen Chronic Disease Hospital, Shenzhen, China
    Sex Transm Infect 83:476-80. 2007
    ..01 cases per 100,000 live births in 1991 to 19.7 cases per 100,000 live births in 2005. Detailed studies of risk factors for syphilis in pregnant women are needed to inform new preventive interventions...
  38. ncbi Chlamydial heat-shock protein-60 antibody and correlation with Chlamydia pneumoniae in atherosclerotic plaques
    Ignatius W Fong
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    J Infect Dis 186:1469-73. 2002
    ..pneumoniae antigen, versus 5.7+/-6.1 mg/L in those without (P=.556). Immune response to CHSP-60 may play a role in atherogenesis, but CRP serum levels does not appear to be related to C. pneumoniae infection...
  39. ncbi Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors: implications for screening and prevention
    Xavier Castellsague
    Institut d Investigacio Biomedica de Bellvitge, Cancer Epidemiology and Registration Unit, Institut Català d Oncologia L Hospitalet de Llobregat, Barcelona, Spain
    J Natl Cancer Inst 98:303-15. 2006
    ..The extent to which human papillomavirus (HPV) infection and cofactors may explain this differential trend is unclear...
  40. ncbi Infection with Chlamydia pneumoniae and risk of multiple sclerosis
    Kassandra L Munger
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 14:141-7. 2003
    ..Chlamydia pneumoniae (Cpn) has been proposed as a possible etiologic agent for multiple sclerosis (MS), but results of previous studies are conflicting...
  41. ncbi Chlamydia trachomatis and invasive cervical cancer: a pooled analysis of the IARC multicentric case-control study
    Jennifer S Smith
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 111:431-9. 2004
    ..0; 95% CI = 0.53-1.9) in HPV DNA-positive women. An association of C. trachomatis with squamous cell ICC was found among all cases and control women with or without adjustment for HPV...
  42. ncbi Pelvic inflammatory disease in the People's Republic of China: aetiology and management
    Shang Hong
    The First Clinical College, China Medical University, Shenyang, 110001, China
    Int J STD AIDS 13:568-72. 2002
    ..To study the causes of pelvic inflammatory disease (PID) in Shenyang, Northeastern China, and to assess the efficacy of the syndromic management flowchart for PID recommended by World Health Organization (WHO)...