D P Wolfer

Summary

Country: Switzerland

Publications

  1. ncbi request reprint Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment?
    D P Wolfer
    Institute of Anatomy, University of Zurich, Switzerland
    Exp Physiol 85:627-34. 2000
  2. ncbi request reprint Extended analysis of path data from mutant mice using the public domain software Wintrack
    D P Wolfer
    Institute of Anatomy, University of Zurich, 190 Winterthurerstrasse, Zurich CH 8057, Switzerland
    Physiol Behav 73:745-53. 2001
  3. ncbi request reprint Multiple roles of neurotrypsin in tissue morphogenesis and nervous system development suggested by the mRNA expression pattern
    D P Wolfer
    Institute of Anatomy, University of Zurich, Zurich, CH 8057, Switzerland
    Mol Cell Neurosci 18:407-33. 2001
  4. ncbi request reprint Assessing the effects of the 129/Sv genetic background on swimming navigation learning in transgenic mutants: a study using mice with a modified beta-amyloid precursor protein gene
    D P Wolfer
    Department of Anatomy, University of Zurich, Switzerland
    Brain Res 771:1-13. 1997
  5. ncbi request reprint Similar target, different effects: late-onset ataxia and spatial learning in prion protein-deficient mouse lines
    P Valenti
    Institute of Anatomy, University of Zurich, Switzerland
    Neurogenetics 3:173-84. 2001
  6. ncbi request reprint Enriched early experiences of mice underexpressing the beta-amyloid precursor protein restore spatial learning capabilities but not normal openfield behavior of adult animals
    P Tremml
    Institute of Anatomy, University of Zurich Irchel, Zurich, Switzerland
    Genes Brain Behav 1:230-41. 2002
  7. ncbi request reprint Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene
    P Tremml
    Institute of Anatomy, University of Zurich Irchel, Zurich, Switzerland
    Behav Brain Res 95:65-76. 1998
  8. ncbi request reprint The impact of genetic background on neurodegeneration and behavior in seizured mice
    M H Mohajeri
    Division of Psychiatry Research and Institute of Anatomy, University of Zurich, Switzerland
    Genes Brain Behav 3:228-39. 2004
  9. ncbi request reprint Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice
    L Pennanen
    Division of Psychiatry Research, University of Zurich, Zurich, Switzerland
    Genes Brain Behav 5:369-79. 2006
  10. ncbi request reprint Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system
    D P Wolfer
    Institute of Anatomy, University of Zurich, Switzerland
    J Comp Neurol 345:1-32. 1994

Detail Information

Publications20

  1. ncbi request reprint Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment?
    D P Wolfer
    Institute of Anatomy, University of Zurich, Switzerland
    Exp Physiol 85:627-34. 2000
    ....
  2. ncbi request reprint Extended analysis of path data from mutant mice using the public domain software Wintrack
    D P Wolfer
    Institute of Anatomy, University of Zurich, 190 Winterthurerstrasse, Zurich CH 8057, Switzerland
    Physiol Behav 73:745-53. 2001
    ..For noncommercial use, the software can be downloaded free of charge at www.dpwolfer.ch/wintrack...
  3. ncbi request reprint Multiple roles of neurotrypsin in tissue morphogenesis and nervous system development suggested by the mRNA expression pattern
    D P Wolfer
    Institute of Anatomy, University of Zurich, Zurich, CH 8057, Switzerland
    Mol Cell Neurosci 18:407-33. 2001
    ..This developmental expression pattern suggests roles of neurotrypsin in morphogenesis of nonneural tissues, as well as in neural development, in particular in axonal target invasion, synaptogenesis, and Schwann cell differentiation...
  4. ncbi request reprint Assessing the effects of the 129/Sv genetic background on swimming navigation learning in transgenic mutants: a study using mice with a modified beta-amyloid precursor protein gene
    D P Wolfer
    Department of Anatomy, University of Zurich, Switzerland
    Brain Res 771:1-13. 1997
    ..Creating congenic lines by backcrossing to an inbred strain is unlikely to enhance the sensitivity of the Morris test. Backcrossing to 129/Sv(ev) may even reduce it...
  5. ncbi request reprint Similar target, different effects: late-onset ataxia and spatial learning in prion protein-deficient mouse lines
    P Valenti
    Institute of Anatomy, University of Zurich, Switzerland
    Neurogenetics 3:173-84. 2001
    ....
  6. ncbi request reprint Enriched early experiences of mice underexpressing the beta-amyloid precursor protein restore spatial learning capabilities but not normal openfield behavior of adult animals
    P Tremml
    Institute of Anatomy, University of Zurich Irchel, Zurich, Switzerland
    Genes Brain Behav 1:230-41. 2002
    ..This implies that some behavioral impairments related to beta-APP malfunction may be corrected through simple treatments...
  7. ncbi request reprint Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene
    P Tremml
    Institute of Anatomy, University of Zurich Irchel, Zurich, Switzerland
    Behav Brain Res 95:65-76. 1998
    ..Further, the manifestation and time course of behavioral yet not neuropathological symptoms in betaAPP mutant mice resemble in some aspects those of the human Down's syndrome...
  8. ncbi request reprint The impact of genetic background on neurodegeneration and behavior in seizured mice
    M H Mohajeri
    Division of Psychiatry Research and Institute of Anatomy, University of Zurich, Switzerland
    Genes Brain Behav 3:228-39. 2004
    ....
  9. ncbi request reprint Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice
    L Pennanen
    Division of Psychiatry Research, University of Zurich, Zurich, Switzerland
    Genes Brain Behav 5:369-79. 2006
    ..In addition, a modest disinhibition of exploratory behavior at 6 months of age was confirmed in the open field and the elevated O-maze and was more pronounced during aging...
  10. ncbi request reprint Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system
    D P Wolfer
    Institute of Anatomy, University of Zurich, Switzerland
    J Comp Neurol 345:1-32. 1994
    ....
  11. ncbi request reprint Increased flexibility and selectivity in spatial learning of transgenic mice ectopically expressing the neural cell adhesion molecule L1 in astrocytes
    D P Wolfer
    Department of Anatomy, University of Zurich, Switzerland
    Eur J Neurosci 10:708-17. 1998
    ....
  12. pmc Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein
    F Magara
    Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Proc Natl Acad Sci U S A 96:4656-61. 1999
    ..In addition, both mutations drastically increase the frequency and severity of callosal agenesis and hippocampal commissure defects in mouse lines with 129/SvEv or 129/Ola background...
  13. ncbi request reprint Paw preference and intra-/infrapyramidal mossy fibers in the hippocampus of the mouse
    H P Lipp
    Institute of Anatomy, University of Zurich Irchel, Switzerland
    Behav Genet 26:379-90. 1996
    ..In addition, the data provide another example of correlations between IIP-MF variations and nonspatial behavior...
  14. ncbi request reprint Genetically modified mice and cognition
    H P Lipp
    Institute of Anatomy, University of Zurich, Switzerland
    Curr Opin Neurobiol 8:272-80. 1998
    ....
  15. ncbi request reprint Expression of neuroserpin, an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse
    S R Krueger
    Department of Biochemistry, University of Zurich, CH 8057 Zurich, Switzerland
    J Neurosci 17:8984-96. 1997
    ..During development, neuroserpin may attenuate extracellular proteolysis related to processes such as neuronal migration, axogenesis, or the formation of mature synaptic connections...
  16. doi request reprint Testing cognitive navigation in unknown territories: homing pigeons choose different targets
    N Blaser
    Institute of Anatomy, University of Zurich, 8057 Zurich, Switzerland
    J Exp Biol 216:3123-31. 2013
    ..This implies that the pigeons knew their geographical position in relation to the targets, and chose a flight direction according to their locally manipulated needs - clearly the essence of a cognitive navigational map. ..
  17. ncbi request reprint Neurotrypsin, a novel multidomain serine protease expressed in the nervous system
    T P Gschwend
    Institute of Biochemistry, University of Zurich, Switzerland
    Mol Cell Neurosci 9:207-19. 1997
    ....
  18. ncbi request reprint A 2-year longitudinal study of swimming navigation in mice devoid of the prion protein: no evidence for neurological anomalies or spatial learning impairments
    H P Lipp
    Institute of Anatomy, University of Zurich Irchel, Zurich, Switzerland
    Behav Brain Res 95:47-54. 1998
    ..The reasons for the discrepancy between different knockout experiments require experimental clarification, however...
  19. doi request reprint Consistent behavioral phenotype differences between inbred mouse strains in the IntelliCage
    S Krackow
    Institute of Anatomy, University of Zurich, Zurich, Switzerland
    Genes Brain Behav 9:722-31. 2010
    ....
  20. ncbi request reprint Comparative effects of exposure to an organophosphate pesticide on locomotor activity of laboratory mice and five species of wild rodents
    G Dell'omo
    Division of Neuroanatomy and Behavior, Institute of Anatomy, University of Zurich Irchel, CH 8057 Zurich, Switzerland
    Bull Environ Contam Toxicol 70:138-45. 2003