Susanne Walitza

Summary

Country: Switzerland

Publications

  1. doi request reprint [The school child with ADHD]
    S Walitza
    Kinder und Jugendpsychiatrischer Dienst Kanton Zürich, Universitätsklinik Zürich
    Ther Umsch 69:467-73. 2012
  2. pmc Trio study and meta-analysis support the association of genetic variation at the serotonin transporter with early-onset obsessive-compulsive disorder
    Susanne Walitza
    University Clinics for Child and Adolescent Psychiatry, University of Zurich, Switzerland Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Germany Neuroscience Center Zürich, University of Zurich and ETH Zurich, Switzerland Electronic address
    Neurosci Lett 580:100-3. 2014
  3. doi request reprint Pilot study on HTR2A promoter polymorphism, -1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive-compulsive disorder
    Susanne Walitza
    Hospital of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032, Zurich, Switzerland
    J Neural Transm 119:507-15. 2012
  4. doi request reprint Genetics of early-onset obsessive-compulsive disorder
    Susanne Walitza
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    Eur Child Adolesc Psychiatry 19:227-35. 2010
  5. pmc Obsessive-compulsive disorder in children and adolescents
    Susanne Walitza
    Zentrum für Kinder und Jugendpsychiatrie, Universitat Zurich, Germany
    Dtsch Arztebl Int 108:173-9. 2011
  6. doi request reprint Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    J Neural Transm 115:1071-8. 2008
  7. doi request reprint Pilot study: potential transcription markers for adult attention-deficit hyperactivity disorder in whole blood
    Edna Grunblatt
    Hospital of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032 Zurich, Switzerland
    Atten Defic Hyperact Disord 4:77-84. 2012
  8. ncbi request reprint Transmission disequilibrium analysis of the functional 5-HT3A receptor variant C178T in early-onset obsessive compulsive-disorder
    Rainald Mossner
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    J Psychopharmacol 21:833-6. 2007
  9. doi request reprint Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder
    Regina Taurines
    Hospital of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    World J Biol Psychiatry 12:104-8. 2011
  10. doi request reprint In vitro study methodologies to investigate genetic aspects and effects of drugs used in attention-deficit hyperactivity disorder
    Edna Grunblatt
    Department of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032, Zurich, Switzerland
    J Neural Transm 120:131-9. 2013

Detail Information

Publications28

  1. doi request reprint [The school child with ADHD]
    S Walitza
    Kinder und Jugendpsychiatrischer Dienst Kanton Zürich, Universitätsklinik Zürich
    Ther Umsch 69:467-73. 2012
    ..However, many of these children also have resources. When fascinated by a task, they may show persistence and commitment...
  2. pmc Trio study and meta-analysis support the association of genetic variation at the serotonin transporter with early-onset obsessive-compulsive disorder
    Susanne Walitza
    University Clinics for Child and Adolescent Psychiatry, University of Zurich, Switzerland Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Germany Neuroscience Center Zürich, University of Zurich and ETH Zurich, Switzerland Electronic address
    Neurosci Lett 580:100-3. 2014
    ..We conclude that the 5-HTTLPR is currently the single best supported risk variant for OCD, in regards of early-onset OCD, albeit of modest effect size and the possibility that the conferred risk might not be specific to OCD. ..
  3. doi request reprint Pilot study on HTR2A promoter polymorphism, -1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive-compulsive disorder
    Susanne Walitza
    Hospital of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032, Zurich, Switzerland
    J Neural Transm 119:507-15. 2012
    ..56 [95% CI (1.32, 142.84); p = 0.020]. These results pointed to the functional importance of this promoter region of HTR2A; it influenced the occurrence, the onset, and the severity of OCD...
  4. doi request reprint Genetics of early-onset obsessive-compulsive disorder
    Susanne Walitza
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    Eur Child Adolesc Psychiatry 19:227-35. 2010
    ..Genome-wide association analyses are in progress and the results will promote further independent replication studies. The consideration of subtypes regarding age of onset, symptom dimensions and/or comorbid disorders is needed...
  5. pmc Obsessive-compulsive disorder in children and adolescents
    Susanne Walitza
    Zentrum für Kinder und Jugendpsychiatrie, Universitat Zurich, Germany
    Dtsch Arztebl Int 108:173-9. 2011
    ..In this review, we summarize the manifestations, comorbidity, pathophysiology, and course of this disease as well as current modes of diagnosis and treatment...
  6. doi request reprint Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    J Neural Transm 115:1071-8. 2008
    ..No evidence of transmission disequilibrium was detected for alleles of the DAT1 and COMT polymorphisms. These polymorphisms do not appear to play a major role in the genetic predisposition to early onset OCD in our study group...
  7. doi request reprint Pilot study: potential transcription markers for adult attention-deficit hyperactivity disorder in whole blood
    Edna Grunblatt
    Hospital of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032 Zurich, Switzerland
    Atten Defic Hyperact Disord 4:77-84. 2012
    ....
  8. ncbi request reprint Transmission disequilibrium analysis of the functional 5-HT3A receptor variant C178T in early-onset obsessive compulsive-disorder
    Rainald Mossner
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    J Psychopharmacol 21:833-6. 2007
    ..51 (95% CI 0.36-0.65). This argues against an involvement of the 5-HT(3A) receptor in the polygenic aetiology of early-onset OCD...
  9. doi request reprint Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder
    Regina Taurines
    Hospital of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    World J Biol Psychiatry 12:104-8. 2011
    ....
  10. doi request reprint In vitro study methodologies to investigate genetic aspects and effects of drugs used in attention-deficit hyperactivity disorder
    Edna Grunblatt
    Department of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032, Zurich, Switzerland
    J Neural Transm 120:131-9. 2013
    ..In this review, different methods will be referred in particular to ADHD findings, and new techniques will be mentioned for future studies of drug or genetic effects in vitro...
  11. doi request reprint Prospective follow-up studies found no chromosomal mutagenicity of methylphenidate therapy in ADHD affected children
    Susanne Walitza
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    Toxicol Lett 193:4-8. 2010
    ..Although the only two available epidemiological studies do not report elevated risk for MPH exposure, the results are not conclusive yet, and further monitoring of exposed populations is suggested...
  12. doi request reprint Comparing tomographic EEG neurofeedback and EMG biofeedback in children with attention-deficit/hyperactivity disorder
    Stefano Maurizio
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland Neuroscience Center Zurich, University of Zurich and ETH Zurich, Switzerland
    Biol Psychol 95:31-44. 2014
    ..The NF group tended to present individual normalization of trained frequency bands in the ACC during rest across training. The results provide evidence for some specific effects in our small sample, albeit only to a small extent. ..
  13. doi request reprint Altered peripheral BDNF mRNA expression and BDNF protein concentrations in blood of children and adolescents with autism spectrum disorder
    Regina Taurines
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstraße 15, 97080, Wuerzburg, Germany
    J Neural Transm 121:1117-28. 2014
    ..Further studies may eventually contribute to the identification of distinct peripheral mRNA expression and protein concentration patterns possibly supporting diagnostic and therapeutic processes...
  14. doi request reprint The feedback-related negativity (FRN) revisited: new insights into the localization, meaning and network organization
    Tobias U Hauser
    University Clinics for Child and Adolescent Psychiatry UCCAP, University of Zurich, Neumunsterallee 9, 8032 Zurich, Switzerland Neuroscience Center Zurich, University of Zurich and ETH Zurich, Switzerland
    Neuroimage 84:159-68. 2014
    ..These findings should enable us to study the processing of surprise and adjustment signals in the dACC in healthy and also in psychiatric patients. ..
  15. doi request reprint Conflict monitoring and error processing: new insights from simultaneous EEG-fMRI
    Reto Iannaccone
    University Clinics for Child and Adolescent Psychiatry UCCAP, University of Zurich, Zurich, Switzerland PhD Program in Integrative Molecular Medicine, University of Zurich, Zurich, Switzerland
    Neuroimage 105:395-407. 2015
    ..Moreover, the overlap of ERN- and N2-informed fMRI activation in the pre-SMA provides new evidence that these ERP components share conflict related processing functions and are thus not completely separable...
  16. doi request reprint Effects of methylphenidate: the cellular point of view
    Jasmin Bartl
    Clinical Neurochemistry Laboratory, Clinic and Policlinic for Psychiatry, Psychosomatic and Psychotherapy, University of Wurzburg, Germany
    Atten Defic Hyperact Disord 2:225-32. 2010
    ..These data point to diverse effects of MPH on cell metabolism independent of inhibiting DAT...
  17. pmc The neurobiological link between OCD and ADHD
    Silvia Brem
    University Clinics of Child and Adolescent Psychiatry, University of Zurich, Neumunsterallee 9, 8032, Zurich, Switzerland
    Atten Defic Hyperact Disord 6:175-202. 2014
    ..This article reviews the current literature of neuroimaging, neurochemical circuitry, neuropsychological and genetic findings considering similarities as well as differences between OCD and ADHD. ..
  18. doi request reprint Role of the medial prefrontal cortex in impaired decision making in juvenile attention-deficit/hyperactivity disorder
    Tobias U Hauser
    University Clinics for Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland2Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland3Wellcome Trust Centre for Neuroimaging, University College London, Londo
    JAMA Psychiatry 71:1165-73. 2014
    ..However, the precise learning and decision-making deficits and their neurobiological correlates in ADHD are not well known...
  19. pmc Cognitive flexibility in adolescence: neural and behavioral mechanisms of reward prediction error processing in adaptive decision making during development
    Tobias U Hauser
    University Clinics for Child and Adolescent Psychiatry UCCAP, University of Zurich, Neumunsterallee 9, 8032 Zurich, Switzerland Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, United Kingdom Neuroscience Center Zurich, University and ETH Zurich, Switzerland Electronic address
    Neuroimage 104:347-54. 2015
    ....
  20. doi request reprint 5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway
    Zoya Marinova
    Hospital of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, 8032 Zurich, Switzerland
    Prog Neuropsychopharmacol Biol Psychiatry 44:64-72. 2013
    ..In conclusion, our results suggest that DOI protects SK-N-SH cells against serum deprivation through ERK pathway activation. They imply 5-HT2A receptor modulation as a potential target for neuroprotection...
  21. pmc Does methylphenidate cause a cytogenetic effect in children with attention deficit hyperactivity disorder?
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Environ Health Perspect 115:936-40. 2007
    ..Assessment and treatment of patients were performed during inpatient or outpatient health care. The measure for genomic damage was the frequency of micronuclei, a subset of chromosomal aberrations, in peripheral lymphocytes...
  22. doi request reprint Reduced NoGo-anteriorisation during continuous performance test in deletion syndrome 22q11.2
    Marcel Romanos
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Clinic of Wuerzburg, Fuechsleinstrasse 15, 97074 Wuerzburg, Germany
    J Psychiatr Res 44:768-74. 2010
    ..Despite recent reports of structural alterations of the ACC in DS22q11.2 our findings suggest that response-inhibition mediated by the ACC is not impaired in DS22q11.2...
  23. pmc DIRAS2 is associated with adult ADHD, related traits, and co-morbid disorders
    Andreas Reif
    Department of Psychiatry, University of Wurzburg, Wurzburg, Germany
    Neuropsychopharmacology 36:2318-27. 2011
    ..031). Additional SNPs showed association with personality scores (p=0.008-0.048). Converging lines of evidence implicate genetic variance in the promoter region of DIRAS2 in the etiology of ADHD and co-morbid impulsive disorders...
  24. doi request reprint Neuroimaging of cognitive brain function in paediatric obsessive compulsive disorder: a review of literature and preliminary meta-analysis
    Silvia Brem
    Department of Child and Adolescent Psychiatry, University of Zurich, Neumunsterallee 9, 8032 Zurich, Switzerland
    J Neural Transm 119:1425-48. 2012
    ....
  25. doi request reprint Imaging genetics in obsessive-compulsive disorder: linking genetic variations to alterations in neuroimaging
    Edna Grunblatt
    University Clinics for Child and Adolescent Psychiatry UCCAP, University of Zurich, Neumuensterallee 9, 8032 Zurich, Switzerland Neuroscience Center Zurich, University of Zurich and ETH Zurich, Switzerland Electronic address
    Prog Neurobiol 121:114-24. 2014
    ....
  26. ncbi request reprint Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder
    Rainald Mossner
    Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
    Int J Neuropsychopharmacol 9:437-42. 2006
    ..58 (95% CI 0.98-6.82). In conclusion, the results link TPH2 variations to the pathogenesis of early-onset OCD and further support the aetiological relevance of 5-HT signalling in OCD...
  27. doi request reprint First clinical trial of tomographic neurofeedback in attention-deficit/hyperactivity disorder: evaluation of voluntary cortical control
    Martina D Liechti
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    Clin Neurophysiol 123:1989-2005. 2012
    ..Tomographic neurofeedback (tNF) training was evaluated as a treatment for attention-deficit/hyperactivity disorder (ADHD). To investigate the specificity of the treatment, outcomes were related to learning during tNF...
  28. pmc Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?
    Veit Roessner
    Department of Child and Adolescent Psychiatry, University of Goettingen, Goettingen, Germany
    Behav Brain Funct 3:64. 2007
    ..abstract:..