Research Topics
| A ZineSummaryAffiliation: University of Lausanne Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
Distinct population of hair cell progenitors can be isolated from the postnatal mouse cochlea using side population analysisEtienne Savary
Institute of Neuroscience, INSERM U 583, Montpellier, France
Stem Cells 25:332-9. 2007..Our observation that these SP cells are capable of differentiating into HC-like cells implies a possible use for such cells (i.e., the replacement of lost auditory HCs within damaged cochlea)...
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner earA Zine
Institute of Physiology, University of Lausanne, 1005 Lausanne, Switzerland
J Neurosci 21:4712-20. 2001..These data indicate that Hes1 and Hes5 participate together for the control of inner ear hair cell production, likely through the negative regulation of Math1...
Notch/Notch ligands and Math1 expression patterns in the organ of Corti of wild-type and Hes1 and Hes5 mutant miceAzel Zine
Institute of Physiology, University of Lausanne, 7 rue du Bugnon, CH 1005, Lausanne, Switzerland
Hear Res 170:22-31. 2002..Our study suggests complex specific relationships between Notch signaling, Math1 and Hes1/Hes5 in the control of hair cell differentiation in the developing organ of Corti...
Notch signaling regulates the pattern of auditory hair cell differentiation in mammalsA Zine
Institute of Physiology, University of Lausanne, Switzerland
Development 127:3373-83. 2000..Our data suggest that the Notch1 signaling pathway is involved in a complex interplay between the consequences of different ligand-Notch1 combinations during cochlear morphogenesis and the phases of hair cell differentiation...
Molecular mechanisms that regulate auditory hair-cell differentiation in the mammalian cochleaAzel Zine
Universite de Montpellier I, Institute des Neurosciences de Montpellier, INSERM U583, 34090 Montpellier, France
Mol Neurobiol 27:223-38. 2003....
D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation traumaAdrien A Eshraghi
Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida 33136-1015, USA
Otol Neurotol 27:504-11. 2006..CONCLUSION: Hearing loss caused by cochlear implant electrode insertion trauma in guinea pigs has both acute and delayed components. The delayed component can be prevented by treating the cochlea with D-JNKI-1...
