Research Topics
Species | Evgeny M ZdobnovSummaryAffiliation: University of Geneva Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
Quantification of insect genome divergenceEvgeny M Zdobnov
University of Geneva Medical School, Department of Genetic Medicine and Development, Geneva 1211, Switzerland
Trends Genet 23:16-20. 2007..Our results show that there is only limited selection for conservation of gene order and reveal a few hundred genes, proximity among which seems to be vital...
Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoesRobert M Waterhouse
Division of Cell and Molecular Biology, Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, UK
Science 316:1738-43. 2007..These dynamics reflect in part continuous readjustment between accommodation and rejection of pathogens and suggest how innate immunity may have evolved...
Computational and transcriptional evidence for microRNAs in the honey bee genomeDaniel B Weaver
Bee Power, LP, Lynn Grove Road, 16481 CR 319, Navasota, TX 77868, USA
Genome Biol 8:R97. 2007..The recently sequenced honey bee genome provides an opportunity to detect novel miRNAs in both this species and others, and to begin to infer the roles of miRNAs in honey bee development...
The bovine lactation genome: insights into the evolution of mammalian milkDanielle G Lemay
Department of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, CA 95616, USA
Genome Biol 10:R43. 2009..The newly assembled Bos taurus genome sequence enables the linkage of bovine milk and lactation data with other mammalian genomes...
New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic featuresCaroline Tapparel
Central Laboratory of Virology, Division of Infectious Diseases, University of Geneva Hospitals, Geneva, Switzerland
BMC Genomics 8:224. 2007..The lack of HRV full-length genome sequences and the absence of analysis comparing picornaviruses at the whole genome level limit our knowledge of the genomic features supporting these differences...
Expression profiles of urbilaterian genes uniquely shared between honey bee and vertebratesToshiaki Matsui
Department of Applied Biological Sciences, School of Agricultural Sciences, Nagoya University, Chikusa, Nagoya 464 8601, Japan
BMC Genomics 10:17. 2009....
Loss of Dicer in Sertoli cells has a major impact on the testicular proteome of miceMarilena D Papaioannou
Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
Mol Cell Proteomics 10:M900587MCP200. 2011..Altogether, our study, which is one of the few in vivo analyses of miRNA effects on protein output, suggests that, at least in our system, miRNAs play a significant role in translation control...
Correlating traits of gene retention, sequence divergence, duplicability and essentiality in vertebrates, arthropods, and fungiRobert M Waterhouse
Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
Genome Biol Evol 3:75-86. 2011....
miROrtho: computational survey of microRNA genesDaniel Gerlach
Department of Genetic Medicine and Development, University of Geneva Medical School, Swiss Institute of Bioinformatics, 1 rue Michel Servet, 1211 Geneva, Switzerland
Nucleic Acids Res 37:D111-7. 2009....
A remarkably stable TipE gene cluster: evolution of insect Para sodium channel auxiliary subunitsJia Li
Department of Genetic Medicine and Development, University of Geneva Medical School, Rue Michel Servet 1, 1211 Geneva, Switzerland
BMC Evol Biol 11:337. 2011..Here, we exploited available arthropod genomic resources to trace the origin of TipE-like genes by mapping their evolutionary histories and examining their genomic architectures...
Quantification of ortholog losses in insects and vertebratesStefan Wyder
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland
Genome Biol 8:R242. 2007....
OrthoDB: the hierarchical catalog of eukaryotic orthologs in 2011Robert M Waterhouse
Department of Genetic Medicine and Development, University of Geneva Medical School, Swiss Institute of Bioinformatics, Rue Michel Servet 1, 1211 Geneva, Switzerland
Nucleic Acids Res 39:D283-8. 2011..OrthoDB is freely accessible from http://cegg.unige.ch/orthodb...
OrthoDB: a hierarchical catalog of animal, fungal and bacterial orthologsRobert M Waterhouse
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland
Nucleic Acids Res 41:D358-65. 2013..With the explosive growth of available data, OrthoDB also provides mapping of newly sequenced genomes and transcriptomes to the current orthologous groups...
Integration of microRNA miR-122 in hepatic circadian gene expressionDavid Gatfield
Department of Molecular Biology, Sciences III, University of Geneva, Geneva, Switzerland
Genes Dev 23:1313-26. 2009....
The Newick utilities: high-throughput phylogenetic tree processing in the UNIX shellThomas Junier
Department of Genetic Medicine and Development, University of Geneva Medical School, 1 rue Michel Servet, 1211 Geneva, Switzerland
Bioinformatics 26:1669-70. 2010..As an example we include an implementation of bootscanning, a procedure for finding recombination breakpoints in viral genomes...
OrthoDB: the hierarchical catalog of eukaryotic orthologsEvgenia V Kriventseva
Department of Genetic Medicine and Development, University of Geneva Medical School, Swiss Institute of Bioinformatics, 1 rue Michel Servet, Geneva, Switzerland
Nucleic Acids Res 36:D271-5. 2008..The database is freely available at http://cegg.unige.ch/orthodb...
Mapping of small RNAs in the human ENCODE regionsChristelle Borel
Department of Genetic Medicine and Development, University of Geneva Medical School and University Hospitals of Geneva, Geneva 1211, Switzerland
Am J Hum Genet 82:971-81. 2008..Notably, most of the remaining candidates showed a larger hybridizing band ( approximately 100 nt) that could be a microRNA precursor. The small RNA transcriptome is emerging as an important and abundant component of the genome function...
Sertoli cell Dicer is essential for spermatogenesis in miceMarilena D Papaioannou
Department of Genetic Medicine and Development, University of Geneva Medical School, 1, rue Michel Servet, 1211 Geneva 4, Switzerland
Dev Biol 326:250-9. 2009..Overall, our results reveal novel essential roles played by the Dicer-dependent pathway in mammalian reproductive function, and thus pave the way for new insights into human infertility...
Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogasterEvgeny M Zdobnov
European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
Science 298:149-59. 2002....
Initial sequencing and comparative analysis of the mouse genomeRobert H Waterston
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
Nature 420:520-62. 2002....
Comparative architectures of mammalian and chicken genomes reveal highly variable rates of genomic rearrangements across different lineagesGuillaume Bourque
Genome Institute of Singapore, Singapore 138672, Republic of Singapore
Genome Res 15:98-110. 2005....
Consistency of genome-based methods in measuring Metazoan evolutionEvgeny M Zdobnov
EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
FEBS Lett 579:3355-61. 2005..The deviations from the clock-like scenario in some lineages are observed consistently by several measures, implicitly confirming their reliability...
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolutionLadeana W Hillier
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
Nature 432:695-716. 2004..The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture...
Protein coding potential of retroviruses and other transposable elements in vertebrate genomesEvgeny M Zdobnov
EMBL Meyerhofstrasse 1, 69117 Heidelberg, Germany
Nucleic Acids Res 33:946-54. 2005..To automatically annotate RETRA genes in other vertebrate genomes, we provide as a tool a set of marker protein domains and a manually refined list of domesticated or ancestral RETRA genes for rescuing genes with vertebrate functions...
AnoEST: toward A. gambiae functional genomicsEvgenia V Kriventseva
European Molecular Biology Laboratory, D69117 Heidelberg, Germany
Genome Res 15:893-9. 2005..Consequently, we expect that many as yet unconfirmed clusters are likely to be actual A. gambiae genes. [AnoEST is publicly available at http://komar.embl.de, and is also accessible as a Distributed Annotation Service (DAS).]...
VectorBase: a home for invertebrate vectors of human pathogensDaniel Lawson
European Bioinformatics Institute EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
Nucleic Acids Res 35:D503-5. 2007....
Genome sequence of Aedes aegypti, a major arbovirus vectorVishvanath Nene
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Science 316:1718-23. 2007..An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species...
The genome of the model beetle and pest Tribolium castaneumStephen Richards
Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
Nature 452:949-55. 2008..Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control...
The genome sequence of the malaria mosquito Anopheles gambiaeRobert A Holt
Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA
Science 298:129-49. 2002..An expressed sequence tag analysis of genes regulated by blood feeding provided insights into the physiological adaptations of a hematophagous insect...
