S Yousefi

Summary

Affiliation: University of Bern
Country: Switzerland

Publications

  1. doi request reprint Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense
    Shida Yousefi
    Institute of Pharmacology, University of Bern, Friedbuhlstrasse 49, CH 3010 Bern, Switzerland
    Nat Med 14:949-53. 2008
  2. doi request reprint Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease
    Shida Yousefi
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    Curr Opin Immunol 24:736-9. 2012
  3. doi request reprint Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps
    S Yousefi
    Institute of Pharmacology, University of Bern, CH 3010 Bern, Switzerland
    Cell Death Differ 16:1438-44. 2009
  4. ncbi request reprint Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
    G Kostylina
    Department of Pharmacology, University of Bern, Friedbuhlstrasse 49, Bern, Switzerland
    Cell Death Differ 15:134-42. 2008
  5. doi request reprint Extracellular DNA traps in allergic, infectious, and autoimmune diseases
    D Simon
    Department of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland
    Allergy 68:409-16. 2013
  6. doi request reprint A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome
    S Salemi
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    Allergy 64:913-8. 2009
  7. doi request reprint Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps
    M Morshed
    Department of Dermatology, Inselspital, Bern University Hospital, Switzerland
    Allergy 67:1127-37. 2012
  8. ncbi request reprint Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils
    S Martinelli
    Department of Pharmacology, University of Bern, Bern, Switzerland
    Oncogene 25:6915-23. 2006
  9. pmc p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene
    Z He
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    Cell Death Differ 20:1415-24. 2013
  10. doi request reprint Autophagy in cells of the blood
    Shida Yousefi
    Institute of Pharmacology, University of Bern, Friedbuhlstrasse 49, CH 3010 Bern, Switzerland
    Biochim Biophys Acta 1793:1461-4. 2009

Collaborators

  • H U Simon
  • M F Fey
  • I Schmid
  • James J Lee
  • M Agostini
  • Dagmar Simon
  • Christoph Mueller
  • A Straumann
  • A Perren
  • Edward Conway
  • Arezoo Daryadel
  • Souzan Salemi
  • Sebastien Conus
  • G Kostylina
  • Z He
  • M Morshed
  • Sibylla Martinelli
  • S Salemi
  • S Martinelli
  • Ekatherina M Vassina
  • Primus E Mullis
  • Andrée Eblé
  • Stephan von Gunten
  • Frank Altznauer
  • Sabine Gisela Plötz
  • T W Mak
  • H Liu
  • M P Tschan
  • G Melino
  • C Stöckle
  • Jan Schmidt-Mende
  • Andrew Ziemiecki
  • L Moretti
  • L Scapozza
  • Carlo Mordasini
  • Clemens A Dahinden
  • David Troi
  • Thomas Reinheckel
  • Leonardo Scapozza
  • Remo Perozzo
  • Christoph Peters
  • Caroline Zwicky
  • S W Lowe
  • V Niggli
  • H G Wendel
  • Johnny Deladoey
  • Remo Filippo Grifone
  • C Baumann
  • Jukka Takala
  • Kurt Baltensperger
  • Iain C A F Robinson
  • Michael Seitz
  • Thomas Schaffner
  • Reinhard Seger
  • Stephan M Jakob
  • Emmanuel Sonnet
  • Paul Czernichow
  • Peter M Villiger
  • Gerhard Binder
  • Mirjana Urosevic
  • Reinhard Dummer
  • Uwe Zangemeister-Wittke
  • Christa Baumann
  • Patrick Antony Oberholzer
  • Christine Thürig
  • Martin H Schöni
  • Peter Vogt
  • Heidrun Behrendt
  • Tim Smith
  • Johannes Ring
  • Ulf Darsow
  • Ekatherina Vassina
  • Rüdiger Hein

Detail Information

Publications20

  1. doi request reprint Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense
    Shida Yousefi
    Institute of Pharmacology, University of Bern, Friedbuhlstrasse 49, CH 3010 Bern, Switzerland
    Nat Med 14:949-53. 2008
    ....
  2. doi request reprint Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease
    Shida Yousefi
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    Curr Opin Immunol 24:736-9. 2012
    ....
  3. doi request reprint Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps
    S Yousefi
    Institute of Pharmacology, University of Bern, CH 3010 Bern, Switzerland
    Cell Death Differ 16:1438-44. 2009
    ..In conclusion, mitochondrial DNA release by neutrophils and NET formation do not require neutrophil death and do also not limit the lifespan of these cells...
  4. ncbi request reprint Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
    G Kostylina
    Department of Pharmacology, University of Bern, Friedbuhlstrasse 49, Bern, Switzerland
    Cell Death Differ 15:134-42. 2008
    ..Moreover, this study identified a new cellular target of NA and future drugs activating GPR109A receptors, the mature neutrophil...
  5. doi request reprint Extracellular DNA traps in allergic, infectious, and autoimmune diseases
    D Simon
    Department of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland
    Allergy 68:409-16. 2013
    ..These new insights into the pathogenesis of inflammatory diseases may open new avenues for targeted therapies...
  6. doi request reprint A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome
    S Salemi
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    Allergy 64:913-8. 2009
    ..However, some patients may develop imatinib resistance because of an acquired T674I mutation, which is believed to prevent drug binding through steric hindrance...
  7. doi request reprint Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps
    M Morshed
    Department of Dermatology, Inselspital, Bern University Hospital, Switzerland
    Allergy 67:1127-37. 2012
    ....
  8. ncbi request reprint Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils
    S Martinelli
    Department of Pharmacology, University of Bern, Bern, Switzerland
    Oncogene 25:6915-23. 2006
    ..These data suggest that drugs that block either c-akt/PKB or signaling molecules located distal to c-akt/PKB may preferentially induce apoptosis of cancer cells as they exhibit no cytotoxicity for immature neutrophils...
  9. pmc p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene
    Z He
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    Cell Death Differ 20:1415-24. 2013
    ..The identification of p73 as a major regulator of autophagy suggests that it may have an important role in preventing or delaying disease and aging by maintaining a homeostatic control. ..
  10. doi request reprint Autophagy in cells of the blood
    Shida Yousefi
    Institute of Pharmacology, University of Bern, Friedbuhlstrasse 49, CH 3010 Bern, Switzerland
    Biochim Biophys Acta 1793:1461-4. 2009
    ..Here, we review these findings, which point to an important role of autophagy in several cellular functions related to host defense...
  11. doi request reprint RhoH/TTF negatively regulates leukotriene production in neutrophils
    Arezoo Daryadel
    Institute of Pharmacology, University of Bern, Bern, Switzerland
    J Immunol 182:6527-32. 2009
    ..Taken together, these data suggest that RhoH/TTF represents an inducible feedback inhibitor in neutrophils that is involved in the limitation of innate immune responses...
  12. pmc Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation
    Sebastien Conus
    Institute of Pharmacology, University of Bern, 3010 Bern, Switzerland
    J Exp Med 205:685-98. 2008
    ....
  13. ncbi request reprint Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha
    Arezoo Daryadel
    Department of Pharmacology, University of Bern, CH 3010 Bern, Switzerland
    J Biol Chem 281:27653-61. 2006
    ..Taken together, apoptotic mature neutrophils release MIF upon short term TNF-alpha stimulation. Therefore, apoptosis may not always occur without the induction of pro-inflammatory mechanisms...
  14. ncbi request reprint cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis
    Ekatherina M Vassina
    Department of Pharmacology, University of Bern, Bern, Switzerland
    Eur J Immunol 36:1975-84. 2006
    ..The cytokine-dependent mechanism of delayed eosinophil apoptosis described here may also apply to other eosinophilic diseases...
  15. ncbi request reprint Variability of isolated autosomal dominant GH deficiency (IGHD II): impact of the P89L GH mutation on clinical follow-up and GH secretion
    Souzan Salemi
    Paediatric Endocrinology, University Children s Hospital, Inselspital, CH 3010 Bern, Switzerland
    Eur J Endocrinol 153:791-802. 2005
    ....
  16. ncbi request reprint Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment
    Stephan von Gunten
    Department of Pharmacology, University of Bern, Friedbuhlstrasse 49, CH 3010 Bern, Switzerland
    Blood 106:1423-31. 2005
    ..The new insights have important implications for the pathogenesis, diagnosis, and treatment of inflammatory diseases such as sepsis and rheumatoid arthritis...
  17. ncbi request reprint Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation
    Sibylla Martinelli
    Department of Pharmacology, University of Bern, CH 3010, Switzerland
    J Biol Chem 279:44123-32. 2004
    ..These data contribute to our understanding regarding changes of gene expression during neutrophil differentiation and IFN-mediated anti-bacterial defense mechanisms...
  18. pmc Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils
    Frank Altznauer
    Dept of Pharmacology, University of Bern, Friedbuhlstrasse 49, CH 3010 Bern, Switzerland
    J Exp Med 199:1343-54. 2004
    ..These data provide new insights into the regulation and function of survivin and have important implications for the pathogenesis, diagnosis, and treatment of inflammatory diseases and cancer...
  19. ncbi request reprint Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis
    Souzan Salemi
    Paediatric Endocrinology, University Children s Hospital, Inselspital, Bern, Switzerland
    Horm Res 65:132-41. 2006
    ..Previous studies have shown variance depending on cell type, transfection technique used, as well as on the method of analysis performed...
  20. ncbi request reprint Use of an anti-interleukin-5 antibody in the hypereosinophilic syndrome with eosinophilic dermatitis
    Sabine Gisela Plötz
    Division of Environmental Dermatology and Allergy GSF TUM, the Center for Allergy and Environment, Technical University, Munich, Germany
    N Engl J Med 349:2334-9. 2003