Research Topics
| Jim YoungSummaryAffiliation: University Hospital Country: Switzerland Publications
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Detail Information
Publications
The clinical diagnosis of acute bacterial rhinosinusitis in general practice and its therapeutic consequencesJim Young
Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
J Clin Epidemiol 56:377-84. 2003..These contradictory results are a salutary reminder that diagnostic indicators need to be evaluated in terms of therapeutic consequences for the patient...
Renal function in patients with HIV starting therapy with tenofovir and either efavirenz, lopinavir or atazanavirJim Young
Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
AIDS 26:567-75. 2012....
Examining assumptions regarding valid electronic monitoring of medication therapy: development of a validation framework and its application on a European sample of kidney transplant patientsKris Denhaerynck
Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056, Basel, Switzerland
BMC Med Res Methodol 8:5. 2008..To assess external validity, we examined if there were indications that using EM affected the sample representativeness...- Efficacy, tolerability and risk factors for virological failure of darunavir-based therapy for treatment-experienced HIV-infected patients: the Swiss HIV Cohort StudyJ Young
Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
HIV Med 12:299-307. 2011..We assessed the efficacy, tolerability and risk factors for virological failure of darunavir for treatment-experienced patients seen in clinical practice... - Virological and immunological responses to efavirenz or boosted lopinavir as first-line therapy for patients with HIVJim Young
Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
Antivir Ther 14:771-9. 2009..It is uncertain which therapy is more effective for patients starting therapy with an advanced infection... - Hierarchical modeling gave plausible estimates of associations between metabolic syndrome and components of antiretroviral therapyJim Young
Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
J Clin Epidemiol 62:632-41. 2009..Hierarchical modeling has been proposed as a solution to the multiple exposure problem. We estimate associations between metabolic syndrome and different components of antiretroviral therapy using both conventional and hierarchical models... - Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient dataJim Young
Basel Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
Lancet 371:908-14. 2008..We undertook a meta-analysis of randomised trials based on individual patients' data to assess whether common signs and symptoms can be used to identify a subgroup of patients who benefit from antibiotics... - Patients' expectations about the benefit of antibiotic treatment: lessons from a randomised controlled trialJim Young
Institut für Klinische Epidemiologie, Universitatsspital Basel, Switzerland
Forsch Komplementarmed Klass Naturheilkd 12:347-9. 2005..Patient expectations may be an important component of a placebo effect, and yet few studies assess how patients' pre-existing expectations affect subsequent health outcomes... - Lipid profiles for antiretroviral-naive patients starting PI- and NNRTI-based therapy in the Swiss HIV cohort studyJim Young
Institut für klinisehe Epidemiologie, Universitatsspital Basel, Basel, Switzerland
Antivir Ther 10:585-91. 2005..We report on medium-term lipid profiles (up to 5 years) for antiretroviral-naive patients starting NNRTI- and PI-based HAART in the Swiss HIV Cohort Study... - Occipitomental (Waters' view) radiographs from general practice: are they adequate?Jim Young
Basel Institute for Clinical Epidemiology, Kantonsspital Basel, Switzerland
Swiss Med Wkly 134:132-5. 2004..With a radiograph that is hard to read the physician should act as if the disease is present or refer the radiograph to a consulting radiologist... - Body fat changes among antiretroviral-naive patients on PI- and NNRTI-based HAART in the Swiss HIV cohort studyJim Young
Institut für Klinische Epidemiologie, Universitatsspital Basel, Basel, Switzerland
Antivir Ther 10:73-81. 2005..Our objective is to show whether such associations are more or less likely for patients on non-nucleoside reverse transcriptase inhibitor (NNRTI)-based HAART... - Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary careMatthias Briel
Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
Arch Intern Med 168:2000-7; discussion 2007-8. 2008..We consider whether antibiotic therapy guided by procalcitonin reduces the use of antibiotics without increasing the restrictions experienced by patients by more than 1 day... - Stable partnership and progression to AIDS or death in HIV infected patients receiving highly active antiretroviral therapy: Swiss HIV cohort studyJim Young
Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, Basle, CH-4031, Switzerland
BMJ 328:15. 2004..06 (0.98 to 1.14) for optimal viral suppression. CONCLUSIONS: A stable partnership is associated with a slower rate of progression to AIDS or death in HIV infected patients receiving HAART... - Shared-decision making in general practice: do patients with respiratory tract infections actually want it?Matthias Briel
Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
Swiss Med Wkly 137:483-5. 2007..There is conflicting evidence on whether patients wish to be involved in medical decisions... - Is unsafe sexual behaviour increasing among HIV-infected individuals?Tracy R Glass
Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
AIDS 18:1707-14. 2004..The number of new diagnoses of HIV infection is rising in the northwestern hemisphere and it is becoming increasingly important to understand the mechanisms behind this trend... - Randomized trial of a computerized coronary heart disease risk assessment tool in HIV-infected patients receiving combination antiretroviral therapyHeiner C Bucher
Basel Institute for Clinical Epidemiology and Biostatistics, Basel, Switzerland
Antivir Ther 15:31-40. 2010..Computerized clinical decision support systems have been advocated to improve the management of patients at risk for CHD but it is unclear whether such systems reduce patients' risk for CHD... - Communication training and antibiotic use in acute respiratory tract infections. A cluster randomised controlled trial in general practiceMatthias Briel
Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
Swiss Med Wkly 136:241-7. 2006..A cluster-randomised controlled trial in general practice.. - Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating antiretroviral therapy--the CASCADE collaboration: a collaboration of 23 cohort studiesMarcel Wolbers
Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
PLoS Med 7:e1000239. 2010..It is not known whether the rate of CD4 cell decline prior to therapy is related to prognosis and should, therefore, influence the decision on when to initiate cART... 
Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671]Matthias Briel
Basel Institute for Clinical Epidemiology, University Hospital Basel, CH 4031 Basel, Switzerland
BMC Fam Pract 6:34. 2005..The aim of this trial is to compare a ProCT-guided antibiotic therapy with a standard approach based on evidence-based guidelines for patients with ARTI in primary care...- The value of a Waters' projectionJim Young
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:512-3; author reply 513. 2003 - Nonadherence with immunosuppressive drugs: U.S. compared with European kidney transplant recipientsKris Denhaerynck
University of Basel, Switzerland
Prog Transplant 16:206-14. 2006..42). CONCLUSION: This is the first study showing differences in prevalence of nonadherence between European and US patients and among European patients. Further research should aim at unraveling the dynamics explaining these differences...