Research Topics
Species | F M WurstSummaryAffiliation: University of Basel Country: Switzerland Publications
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Publications
The ethanol conjugate ethyl glucuronide is a useful marker of recent alcohol consumptionFriedrich Martin Wurst
Psychiatric University Hospital, University of Basel, Switzerland
Alcohol Clin Exp Res 26:1114-9. 2002....
Forensic confirmatory analysis of ethyl sulfate--a new marker for alcohol consumption--by liquid-chromatography/electrospray ionization/tandem mass spectrometrySebastian Dresen
Institute of Legal Medicine, Forensic Toxicology, University Hospital, Freiburg, Germany
J Am Soc Mass Spectrom 15:1644-8. 2004..The determination of EtS can be used in addition to EtG as proof of ethanol consumption in workplace monitoring programs...
[Direct ethanol metabolite ethyl glucuronide. Its value as alcohol intake and recurrence marker, methods of detection and prospects]F M Wurst
Psychiatrische Universitätsklinik Basel
Psychiatr Prax 27:367-71. 2000..The complementary use of EtG together with other upcoming markers of alcohol consumption like phosphatidyl ethanol should lead to an improvement in treatment outcome, quality of life and cost reduction...
Emerging biomarkers: new directions and clinical applicationsFriedrich M Wurst
Psychiatric University Hospital, Wilhelm Klein Strasse 27, CH 4025 Basel, Switzerland
Alcohol Clin Exp Res 29:465-73. 2005....
On sensitivity, specificity, and the influence of various parameters on ethyl glucuronide levels in urine--results from the WHO/ISBRA studyFriedrich Martin Wurst
Psychiatric University Hospital, University of Basel, Switzerland
Alcohol Clin Exp Res 28:1220-8. 2004..Our aim was to study sensitivity, specificity, and the influence of various parameters on EtG levels in urine...
Ethyl glucuronide--the direct ethanol metabolite on the threshold from science to routine useFriedrich Martin Wurst
Psychiatric University Hospital, University of Basel, Switzerland
Addiction 98:51-61. 2003..The use of this marker alone and complementary with other biological state markers and self-reports is expected to lead to significant improvement in treatment outcome, therapy efficacy and cost reduction...
Concentration of fatty acid ethyl esters in hair of alcoholics: comparison to other biological state markers and self reported-ethanol intakeFriedrich Martin Wurst
Psychiatric University Hospital and Department Central Laboratory, University of Basel, Switzerland
Alcohol Alcohol 39:33-8. 2004..Additionally, we propose a cut-off value of FAEE to distinguish teetotallers/moderate/social drinkers from alcoholics or individuals drinking at harmful levels...
Ethyl glucuronide: on the time course of excretion in urine during detoxificationFriedrich Martin Wurst
Psychiatric University Hospital, University of Basel, Wilhelm Klein Strasse 27, CH 4025 Basel, Switzerland
Addict Biol 7:427-34. 2002..Furthermore our preliminary data indicate, that there is no significant difference for EtG concentration in urine when correlated to group variables such as age, seizures and hospitalizations...
Ethyl glucuronide discloses recent covert alcohol use not detected by standard testing in forensic psychiatric inpatientsFriedrich Martin Wurst
Psychiatric University Hospital, University of Basel, Wilhelm Klein Strasse 27, CH 4025 Basel, Switzerland
Alcohol Clin Exp Res 27:471-6. 2003..Our aim was to assess their potential for detecting recent covert alcohol use under controlled conditions...
Measurement of direct ethanol metabolites in a case of a former driving under the influence (DUI) of alcohol offender, now claiming abstinenceFriedrich M Wurst
Psychiatric University Hospital, University of Basel, Basel, Switzerland
Int J Legal Med 122:235-9. 2008..A careful individual interpretation of the results for the different markers, however, is an absolute necessity...
A clinical lesson: glioblastoma multiforme masquerading as depression in a chronic alcoholicBenedikt Habermeyer
Psychiatric University Clinic, University of Basel, Switzerland
Alcohol Alcohol 43:31-3. 2008..To highlight the need to consider other medical conditions when the presentation initially appears to be alcohol-related...
Multiple cerebral metastases mimicking Wernicke's encephalopathy in a chronic alcoholicOzgur Yaldizli
Psychiatric University Clinic, University of Basel, Wilhelm-Klein-Strasse 27, Basel, Switzerland
Alcohol Alcohol 41:678-80. 2006..RESULTS: The findings illustrate the importance of initially maintaining a tentative attitude toward causation of symptoms and the role of brain imaging in formulating an accurate diagnosis...
Gender differences for ghrelin levels in alcohol-dependent patients and differences between alcoholics and healthy controlsFriedrich M Wurst
Psychiatric University Clinic, University of Basel, Switzerland
Alcohol Clin Exp Res 31:2006-11. 2007..Since data published to date on the potential role of ghrelin as state and/or trait marker in alcoholism and the association with craving are controversial, we aimed at further elucidating these aspects. Patients and..
Phosphatidylethanol as a sensitive and specific biomarker: comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydrate-deficient transferrinSusanne Hartmann
Psychiatric University Clinic, Basel, Switzerland
Addict Biol 12:81-4. 2007..802). Our data suggest that PEth has potential to be a sensitive and specific biomarker, having been found in previous studies to indicate longer lasting intake of higher amounts of alcohol...
Measurement of direct ethanol metabolites suggests higher rate of alcohol use among pregnant women than found with the AUDIT--a pilot study in a population-based sample of Swedish womenFriedrich Martin Wurst
Psychiatric University Clinic, Basel, Switzerland
Am J Obstet Gynecol 198:407.e1-5. 2008..The objective of the study was to investigate whether biomarkers of alcohol consumption would provide additional information to the use of a validated alcohol questionnaire in pregnant women...
Alcoholism, craving, and hormones: the role of leptin, ghrelin, prolactin, and the pro-opiomelanocortin system in modulating ethanol intakeFriedrich Martin Wurst
Christian Doppler Clinic, Department of Psychiatry and Psychotherapy II Addiction Medicine, Paracelsus Medical University, Salzburg, Austria
Alcohol Clin Exp Res 31:1963-7. 2007..The goal of this mini-review is to discuss the results of some recent investigations of the potential interactions of these systems with acute and chronic alcohol responses...
No association of dopamine receptor sensitivity in vivo with genetic predisposition for alcoholism and DRD2/DRD3 gene polymorphisms in alcohol dependenceGerhard A Wiesbeck
Division of Substance Use Disorders, Psychiatric University Hospital Basel, Switzerland
Addict Biol 11:72-5. 2006....
Ethyl sulphate: a direct ethanol metabolite reflecting recent alcohol consumptionFriedrich Martin Wurst
Psychiatric University Clinic, Basel, Switzerland
Addiction 101:204-11. 2006..Although its window of assessment is similar to that of ethyl glucuronide (EtG), there are differences between the two markers in their pathways for formation and degradation...
Stability of ethyl glucuronide in urine, post-mortem tissue and blood samplesHaiko Schloegl
Institute of Legal Medicine, University Hospital, Albertstrasse 9, 79104 Freiburg, Germany
Int J Legal Med 120:83-8. 2006..Blood and liver samples of four corpses with negative BACs were stored at RT after addition of 0.1 g% ethanol, and no new formation of EtG was observed...
Distribution of ethyl glucuronide in rib bone marrow, other tissues and body liquids as proof of alcohol consumption before deathHaiko Schloegl
Institute of Forensic Medicine, Forensic Toxicology, University Hospital, Albertstr. 9, D-79104 Freiburg, Germany
Forensic Sci Int 156:213-8. 2006..In these cases, the detectable ethanol might have been produced partially or in total by postmortem fermentation. However, instability of EtG during putrefaction cannot be totally excluded which might result in a total loss of EtG...
Ethyl glucuronide: a biomarker to identify alcohol use by health professionals recovering from substance use disordersGregory E Skipper
Alabama Physician Health Program and University of Alabama Birmingham School of Medicine, Montgomery, Alabama, USA
Alcohol Alcohol 39:445-9. 2004..Incorporation of EtG testing into alcohol abstinence monitoring can strengthen these programs...
Confirmatory analysis of ethylglucuronide in urine by liquid-chromatography/electrospray ionization/tandem mass spectrometry according to forensic guidelinesWolfgang Weinmann
Institute of Legal Medicine, Forensic Toxicology, University Hospital, Freiburg, Germany
J Am Soc Mass Spectrom 15:188-93. 2004....
Leptin levels of alcohol abstainers and detoxification patients are not differentFriedrich Martin Wurst
Psychiatric University Clinic and Department Central Laboratory, University of Basel, Switzerland
Alcohol Alcohol 38:364-8. 2003..CONCLUSIONS: Our preliminary data do not support the hypothesis of leptin as a state or trait marker and suggest only a minor influence of acute intoxication on leptin levels in alcohol detoxification patients...
The usefulness of direct ethanol metabolites in assessing alcohol intake in nonintoxicated male patients in an emergency room settingMiriam Julia Kip
Department of Anesthesiology and Intensive Care Medicine, Charite University Medicine Berlin, Berlin, Germany
Alcohol Clin Exp Res 32:1284-91. 2008....
No significant effect of acute moderate alcohol intake on leptin levels in healthy male volunteersGerhard Dammann
Psychiatric University Clinic, Basel, Switzerland
Addict Biol 10:357-64. 2005..The data do not support the hypothesis of a significant effect of acute moderate alcohol intake on leptin levels in healthy volunteers...
[In-patient suicide -- a comparison of psychiatric in-patient suicides versus a control group of inpatients from the same treatment era without suicide]Manfred Wolfersdorf
, BKH Bayreuth, Bayreuth
Psychiatr Prax 30:14-20. 2003..Suicides received more psychopharmaca...
