H Wennemers

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi request reprint Combinatorial chemistry: a tool for the discovery of new catalysts
    H Wennemers
    Institute of Organic Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Comb Chem High Throughput Screen 4:273-85. 2001
  2. doi request reprint Asymmetric catalysis with peptides
    Helma Wennemers
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Chem Commun (Camb) 47:12036-41. 2011
  3. ncbi request reprint Flexible but with a defined turn-influence of the template on the binding properties of two-armed receptors
    Helma Wennemers
    Department of Chemistry, University of Basel St Johanns Ring 19, 4056 Basel, Switzerland
    Chemistry 9:442-8. 2003
  4. ncbi request reprint Diketopiperazine receptors: a novel class of highly selective receptors for binding small peptides
    H Wennemers
    Institute of Organic Chemistry, University of Basel, Switzerland
    Chemistry 7:3342-7. 2001
  5. ncbi request reprint Selective binding of two-armed diketopiperazine receptors to side-chain-protected peptides
    Matteo Conza
    Institute of Organic Chemistry, University Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    J Org Chem 67:2696-8. 2002
  6. ncbi request reprint Supramolecular and nanochemistry
    Edwin C Constable
    Department of Chemistry, University of Basel, Spitalstrasse 51, CH 4056 Basel
    Chimia (Aarau) 64:877-84. 2010
  7. ncbi request reprint Synthesis and catalysis
    Karl Gademann
    Department of Chemistry, St Johanns Ring 19, CH 4056 Basel
    Chimia (Aarau) 64:859-66. 2010
  8. ncbi request reprint Macrocyclic diketopiperazine receptors: effect of macrocyclization on the binding properties of two-armed receptors
    Jessica Bernard
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Org Lett 9:4283-6. 2007
  9. ncbi request reprint Catalyst-substrate coimmobilization: a strategy for catalysts discovery in split-and-mix libraries
    Philipp Krattiger
    Departement Chemie, Universitat Basel, St Johanns Ring 19, 4056 Basel, Switzerland
    Angew Chem Int Ed Engl 42:1722-4. 2003
  10. doi request reprint Silver nanoparticle formation in different sizes induced by peptides identified within split-and-mix libraries
    Kirsten Belser
    Department of Chemistry, University of Basel, St Johanns Ring 19, 4056 Basel, Switzerland
    Angew Chem Int Ed Engl 48:3661-4. 2009

Collaborators

  • Andreas Pfaltz
  • Karl Gademann
  • Edwin C Constable
  • Christian Ochsenfeld
  • Jefferson D Revell
  • Markus Wiesner
  • Philipp Krattiger
  • Gregory Upert
  • Michael Kumin
  • Matteo Conza
  • Kirsten Belser
  • Michael Kuemin
  • Xiao Yang Gong
  • Alexandra R Stettler
  • Jessica Bernard
  • Jessica Grun
  • Christoph A Merten
  • Sabine Schweizer
  • T√ľnde Vig Slenters
  • Conelious Pfumbidzai
  • Katharina M Fromm
  • Laurent Mirolo
  • Dominik Dobrunz
  • Sandro Tonazzi
  • Peter C Hauser
  • Maria A Schwarz
  • Louis Sebastian Sonntag
  • Daniel Gantenbein
  • Stanislav Ivan
  • Roman Kovasy
  • Catherine McCarthy

Detail Information

Publications21

  1. ncbi request reprint Combinatorial chemistry: a tool for the discovery of new catalysts
    H Wennemers
    Institute of Organic Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Comb Chem High Throughput Screen 4:273-85. 2001
    ..This review describes the methodologies used so far for the detection of catalytic events and will place particular emphasis on the on-bead screening of one-bead-one-compound libraries...
  2. doi request reprint Asymmetric catalysis with peptides
    Helma Wennemers
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Chem Commun (Camb) 47:12036-41. 2011
    ..The article highlights features that render peptidic organocatalysts unique and attractive for future applications. Challenges such as the design of peptidic catalysts are discussed...
  3. ncbi request reprint Flexible but with a defined turn-influence of the template on the binding properties of two-armed receptors
    Helma Wennemers
    Department of Chemistry, University of Basel St Johanns Ring 19, 4056 Basel, Switzerland
    Chemistry 9:442-8. 2003
    ..Additionally, the results provide a guide for the rational design of two-armed receptors with good binding properties towards peptidic guests...
  4. ncbi request reprint Diketopiperazine receptors: a novel class of highly selective receptors for binding small peptides
    H Wennemers
    Institute of Organic Chemistry, University of Basel, Switzerland
    Chemistry 7:3342-7. 2001
    ....
  5. ncbi request reprint Selective binding of two-armed diketopiperazine receptors to side-chain-protected peptides
    Matteo Conza
    Institute of Organic Chemistry, University Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    J Org Chem 67:2696-8. 2002
    ....
  6. ncbi request reprint Supramolecular and nanochemistry
    Edwin C Constable
    Department of Chemistry, University of Basel, Spitalstrasse 51, CH 4056 Basel
    Chimia (Aarau) 64:877-84. 2010
    ..The following contributions describe various research activities of the Department of Chemistry, University of Basel in the area of nanochemistry and supramolecular chemistry...
  7. ncbi request reprint Synthesis and catalysis
    Karl Gademann
    Department of Chemistry, St Johanns Ring 19, CH 4056 Basel
    Chimia (Aarau) 64:859-66. 2010
    ..Research projects of the Department of Chemistry, University of Basel are reviewed ranging from the synthesis of complex natural products to the development of metalorganic catalysts and organocatalysts...
  8. ncbi request reprint Macrocyclic diketopiperazine receptors: effect of macrocyclization on the binding properties of two-armed receptors
    Jessica Bernard
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Org Lett 9:4283-6. 2007
    ....
  9. ncbi request reprint Catalyst-substrate coimmobilization: a strategy for catalysts discovery in split-and-mix libraries
    Philipp Krattiger
    Departement Chemie, Universitat Basel, St Johanns Ring 19, 4056 Basel, Switzerland
    Angew Chem Int Ed Engl 42:1722-4. 2003
  10. doi request reprint Silver nanoparticle formation in different sizes induced by peptides identified within split-and-mix libraries
    Kirsten Belser
    Department of Chemistry, University of Basel, St Johanns Ring 19, 4056 Basel, Switzerland
    Angew Chem Int Ed Engl 48:3661-4. 2009
    ..Structurally diverse peptides were detected in colorimetric on-bead screenings that generate Ag nanoparticles of different sizes, as confirmed by SEM and X-ray powder diffraction studies...
  11. ncbi request reprint Peptidic catalysts developed by combinatorial screening methods
    Jefferson D Revell
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Curr Opin Chem Biol 11:269-78. 2007
    ..This review summarizes recent developments in the field of catalytically active short-chain peptides, highlighting the combinatorial techniques that have facilitated their discovery...
  12. ncbi request reprint Electrophoretic affinity measurements on microchip. Determination of binding affinities between diketopiperazine receptors and peptide ligands
    Alexandra R Stettler
    Department of Chemistry, University of Basel, Basel, Switzerland
    Electrophoresis 28:1832-8. 2007
    ..We demonstrate the applicability of MC-ACE for the determination of the binding affinities between acid-rich diketopiperazine receptors and basic tripeptides in aqueous solution...
  13. ncbi request reprint Increased structural complexity leads to higher activity: peptides as efficient and versatile catalysts for asymmetric aldol reactions
    Philipp Krattiger
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Org Lett 7:1101-3. 2005
    ....
  14. ncbi request reprint Solid-supported and pegylated H-Pro-Pro-Asp-NHR as catalysts for asymmetric aldol reactions
    Jefferson D Revell
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Biopolymers 84:105-13. 2006
    ..handling, higher solubility, and thereby greater versatility...
  15. ncbi request reprint Peptide-polyethylene glycol conjugates: synthesis and properties of peptides bearing a C-terminal polyethylene glycol chain
    Jessica Grun
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Bioorg Med Chem 14:6197-201. 2006
    ....
  16. doi request reprint Nanoliter plates--versatile tools for the screening of split-and-mix libraries on-bead and off-bead
    Gregory Upert
    Department of Chemistry University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    Chem Commun (Camb) 46:2209-11. 2010
    ..Nanoliter plates are versatile tools for the screening of split-and-mix libraries both on-bead and off-bead. The method was evaluated for the identification of hydrolytically active compounds and enzyme inhibitors...
  17. doi request reprint Effects of terminal functional groups on the stability of the polyproline II structure: a combined experimental and theoretical study
    Michael Kuemin
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    J Am Chem Soc 131:15474-82. 2009
    ..Studies at different pH values verified the electrostatic nature of the observed effects and demonstrate how changes in the protonation state can be used to deliberately stabilize the PPII helix over the PPI helix or vice versa...
  18. doi request reprint Peptide catalyzed asymmetric conjugate addition reactions of aldehydes to nitroethylene--a convenient entry into gamma2-amino acids
    Markus Wiesner
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    J Am Chem Soc 130:5610-1. 2008
    ..The products can be readily converted into gamma2-amino acids, thereby opening an effective direct entry into this important class of compounds...
  19. doi request reprint Tripeptides as efficient asymmetric catalysts for 1,4-addition reactions of aldehydes to nitroolefins--a rational approach
    Markus Wiesner
    Department of Chemistry, University of Basel, St Johanns Ring 19, 4056 Basel, Switzerland
    Angew Chem Int Ed Engl 47:1871-4. 2008
  20. ncbi request reprint Azidoproline containing helices: stabilization of the polyproline II structure by a functionalizable group
    Michael Kumin
    Department of Chemistry, University of Basel, St Johanns Ring 19, CH 4056 Basel, Switzerland
    J Am Chem Soc 129:466-7. 2007
  21. doi request reprint Separating stereoisomers of di-, tri-, and tetrapeptides using capillary electrophoresis with contactless conductivity detection
    Xiao Yang Gong
    Department of Chemistry, University of Basel, Spitalstrasse 51, Basel, Switzerland
    J Sep Sci 31:565-73. 2008
    ..0 microM. The determination of isomeric impurities down to about 1% was found possible. Species showing good separation could also be successfully determined on an electrophoretic lab-on-chip device, with analysis times of a few minutes...