Research Topics
Genomes and Genes | Andrea VolterraSummaryAffiliation: University of Lausanne Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
Glial modulation of synaptic transmission in the hippocampusAndrea Volterra
Department of Cell Biology and Morphology, University of Lausanne, Lausanne, Switzerland
Glia 47:249-57. 2004..In this review, we will focus specifically on the hippocampus and sum up evidence of bidirectional communication between astrocytes and neurons emerging from recent studies using acute slice preparations...
Astrocytes, from brain glue to communication elements: the revolution continuesAndrea Volterra
Department of Cell Biology and Morphology, University of Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
Nat Rev Neurosci 6:626-40. 2005..Examples of their specific and essential roles in normal physiological processes have begun to accumulate, and the number of diseases known to involve defective astrocytes is increasing...
Local Ca2+ detection and modulation of synaptic release by astrocytesMaria Amalia Di Castro
Department of Cell Biology and Morphology, University of Lausanne, Lausanne, Switzerland
Nat Neurosci 14:1276-84. 2011..These data provide direct evidence that astrocytes are integrated in local synaptic functioning in adult brain...
TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrusMirko Santello
Department of Cell Biology and Morphology, University of Lausanne, Lausanne, Switzerland
Neuron 69:988-1001. 2011..These findings demonstrate that gliotransmission and its synaptic effects are controlled not only by astrocyte [Ca(2+)](i) elevations but also by permissive/homeostatic factors like TNFα. VIDEO ABSTRACT:..
Glutamate exocytosis from astrocytes controls synaptic strengthPascal Jourdain
Department of Cell Biology and Morphology, University of Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
Nat Neurosci 10:331-9. 2007..Thus, we provide the first combined functional and ultrastructural evidence for a physiological control of synaptic activity via exocytosis of glutamate from astrocytes...
P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandinsMaria Domercq
Department of Cell Biology and Morphology, University of Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
J Biol Chem 281:30684-96. 2006..The identified pathway may play physiological roles in glial-glial and glial-neuronal communication...
Glutamate release from astrocytes in physiological conditions and in neurodegenerative disorders characterized by neuroinflammationSabino Vesce
Department of Cell Biology and Morphology, University of Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
Int Rev Neurobiol 82:57-71. 2007....
The Ca(V)3.3 calcium channel is the major sleep spindle pacemaker in thalamusSimone Astori
Department of Cell Biology and Morphology, University of Lausanne, CH 1005 Lausanne, Switzerland
Proc Natl Acad Sci U S A 108:13823-8. 2011..Together, these data identify a central role for Ca(V)3.3 channels in the rhythmogenic properties of the sleep-spindle generator and provide a molecular target to elucidate the roles of sleep spindles for brain function and development...
SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: a comparative analysisVanessa Schubert
Department of Cell Biology and Morphology, University of Lausanne, Lausanne, Switzerland
Glia 59:1472-88. 2011....
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamatePaola Bezzi
Department of Cell Biology and Morphology, University of Lausanne, and Cellular Imaging Facility UNIL-CHUV-Technological Development Unit, Switzerland
Nat Neurosci 7:613-20. 2004..These data document the existence of a Ca(2+)-dependent quantal glutamate release activity in glia that was previously considered to be specific to synapses...
TNFα in synaptic function: switching gearsMirko Santello
Department of Cell Biology and Morphology, University of Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
Trends Neurosci 35:638-47. 2012..This functional switch may contribute to cognitive alterations in several brain pathologies...
Astrocytes: powering memoryPaola Bezzi
Department of Cell Biology and Morphology, University of Lausanne, Rue du Bugnon, 9 1005 Lausanne, Switzerland
Cell 144:644-5. 2011..Suzuki et al. (2011) show that astrocytes, glial cells of the brain, play a necessary role in this program by converting glycogen to lactate and transporting it to neurons...
Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer diseaseDaniela Rossi
Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, Via Balzaretti, 9, 20133 Milan, Italy
J Biol Chem 280:42088-96. 2005..Reduced expression of DENN/MADD, a mediator of TNFalpha-PG coupling, might account for the defect. Alteration of this neuromodulatory astrocytic pathway is described here for the first time in relation to Alzheimer disease...
Glial control of synaptic functionEric A Newman
Glia 47:207-8. 2004
