Francois Verrey

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. ncbi request reprint CATs and HATs: the SLC7 family of amino acid transporters
    Francois Verrey
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    Pflugers Arch 447:532-42. 2004
  2. ncbi request reprint WNK4, as thiazides, shuts off NaCl reabsorption to stimulate Na/K exchange
    Francois Verrey
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nephrol Dial Transplant 22:1305-8. 2007
  3. ncbi request reprint System L: heteromeric exchangers of large, neutral amino acids involved in directional transport
    Francois Verrey
    University of Zurich, Institute of Physiology, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Pflugers Arch 445:529-33. 2003
  4. ncbi request reprint Early transcriptional control of ENaC (de)ubiquitylation by aldosterone
    F Verrey
    Institute of Physiology and Centre for Integrative Human Physiology ZIHP, University of Zurich, Zurich, Switzerland
    Kidney Int 73:691-6. 2008
  5. ncbi request reprint Novel renal amino acid transporters
    Francois Verrey
    University of Zurich, Institute of Physiology, CH 8057 Zurich, Switzerland
    Annu Rev Physiol 67:557-72. 2005
  6. ncbi request reprint Short-term aldosterone action on Na,K-ATPase surface expression: role of aldosterone-induced SGK1?
    Francois Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Ann N Y Acad Sci 986:554-61. 2003
  7. ncbi request reprint SGK1: aldosterone-induced relay of Na+ transport regulation in distal kidney nephron cells
    Francois Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Cell Physiol Biochem 13:21-8. 2003
  8. ncbi request reprint Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations
    Simone M R Camargo
    Institute of Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
    Gastroenterology 136:872-82. 2009
  9. ncbi request reprint Recycling of aromatic amino acids via TAT1 allows efflux of neutral amino acids via LAT2-4F2hc exchanger
    Tamara Ramadan
    Zurich Centre for Integrative Human Physiology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    Pflugers Arch 454:507-16. 2007
  10. pmc Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3
    Dustin Singer
    Institute of Physiology and Center for Integrative Human Physiology, University of Zurich, 8057 Zurich, Switzerland
    J Biol Chem 284:19953-60. 2009

Collaborators

Detail Information

Publications59

  1. ncbi request reprint CATs and HATs: the SLC7 family of amino acid transporters
    Francois Verrey
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    Pflugers Arch 447:532-42. 2004
    ..Mutations in b(0,+)-like and y(+)L transporters lead to the hereditary diseases cystinuria and lysinuric protein intolerance (LPI), respectively...
  2. ncbi request reprint WNK4, as thiazides, shuts off NaCl reabsorption to stimulate Na/K exchange
    Francois Verrey
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nephrol Dial Transplant 22:1305-8. 2007
  3. ncbi request reprint System L: heteromeric exchangers of large, neutral amino acids involved in directional transport
    Francois Verrey
    University of Zurich, Institute of Physiology, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Pflugers Arch 445:529-33. 2003
    ..By mediating the regulated flux of these exchange substrates, unidirectional transporters control the activity of system L...
  4. ncbi request reprint Early transcriptional control of ENaC (de)ubiquitylation by aldosterone
    F Verrey
    Institute of Physiology and Centre for Integrative Human Physiology ZIHP, University of Zurich, Zurich, Switzerland
    Kidney Int 73:691-6. 2008
    ....
  5. ncbi request reprint Novel renal amino acid transporters
    Francois Verrey
    University of Zurich, Institute of Physiology, CH 8057 Zurich, Switzerland
    Annu Rev Physiol 67:557-72. 2005
    ..Additionally, cationic amino acids and some other neutral amino acids leave the cell basolaterally via heterodimeric obligatory exchangers...
  6. ncbi request reprint Short-term aldosterone action on Na,K-ATPase surface expression: role of aldosterone-induced SGK1?
    Francois Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Ann N Y Acad Sci 986:554-61. 2003
    ..Results obtained in the Xenopus oocyte expression system suggest the possibility that this effect could be mediated in part by the aldosterone-induced kinase SGK1...
  7. ncbi request reprint SGK1: aldosterone-induced relay of Na+ transport regulation in distal kidney nephron cells
    Francois Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Cell Physiol Biochem 13:21-8. 2003
    ....
  8. ncbi request reprint Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations
    Simone M R Camargo
    Institute of Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
    Gastroenterology 136:872-82. 2009
    ..The expression of B(0)AT1 in kidney was recently shown to depend on its association with collectrin (Tmem27), a protein homologous to the membrane-anchoring domain of angiotensin-converting enzyme (ACE) 2...
  9. ncbi request reprint Recycling of aromatic amino acids via TAT1 allows efflux of neutral amino acids via LAT2-4F2hc exchanger
    Tamara Ramadan
    Zurich Centre for Integrative Human Physiology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    Pflugers Arch 454:507-16. 2007
    ..Taken together, the results suggest that the aromatic amino acid diffusion pathway TAT1 can control neutral amino acid efflux via neighboring exchanger LAT2-4F2hc, by recycling its aromatic influx substrates...
  10. pmc Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3
    Dustin Singer
    Institute of Physiology and Center for Integrative Human Physiology, University of Zurich, 8057 Zurich, Switzerland
    J Biol Chem 284:19953-60. 2009
    ..Taken together, our data indicate that the formerly orphan transporter XT2 functions as a sodium and chloride-de pend ent neutral amino acid transporter that we propose to rename B(0)AT3...
  11. ncbi request reprint The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance
    Markus A Seeger
    Institute of Physiology, Zurich Centre for Integrative Human Physiology ZIHP, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Curr Drug Targets 9:729-49. 2008
    ..The novel transport model merges Jardetzky's alternate access pump mechanism with the rotating site catalysis of F(1)F(0) ATPase and suggests a working hypothesis for the transport mechanism of RND transporters in general...
  12. pmc T-type amino acid transporter TAT1 (Slc16a10) is essential for extracellular aromatic amino acid homeostasis control
    Luca Mariotta
    Institute of Physiology and Zurich Center for Integrative Human Physiology ZIHP, University of Zurich, Zurich, Switzerland
    J Physiol 590:6413-24. 2012
    ..Additionally, it facilitates the release of AAAs across the basolateral membrane of small intestine and proximal kidney tubule epithelial cells, thereby allowing the efflux of other neutral AAs presumably via Lat2-4F2hc...
  13. doi request reprint Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB
    Markus A Seeger
    Institute of Physiology and Zurich Centre for Integrative Human Physiology ZIHP, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nat Struct Mol Biol 15:199-205. 2008
    ..Regain of function for impaired mutants was obtained upon exposure to the reducing agent DTT. The results support the presence of the asymmetric AcrB trimer in E. coli membranes and the functional rotation mechanism...
  14. ncbi request reprint Neutral amino acid transport mediated by ortholog of imino acid transporter SIT1/SLC6A20 in opossum kidney cells
    Zorica Ristic
    Institute of Physiology, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
    Am J Physiol Renal Physiol 290:F880-7. 2006
    ..A similar double role could be envisaged for SIT1 in mammalian kidney proximal tubule and small intestine...
  15. ncbi request reprint Functional cooperation of epithelial heteromeric amino acid transporters expressed in madin-darby canine kidney cells
    Christian Bauch
    Institute of Physiology and Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, Switzerland
    J Biol Chem 278:1316-22. 2003
    ....
  16. ncbi request reprint Steady-state kinetic characterization of the mouse B(0)AT1 sodium-dependent neutral amino acid transporter
    Simone M R Camargo
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057, Zurich, Switzerland
    Pflugers Arch 451:338-48. 2005
    ....
  17. ncbi request reprint Luminal kidney and intestine SLC6 amino acid transporters of B0AT-cluster and their tissue distribution in Mus musculus
    Elisa Romeo
    Institute of Physiology, Univ of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Am J Physiol Renal Physiol 290:F376-83. 2006
    ..It also shows that the structurally highly similar orphan transporters XT2 and XT3 have the same luminal but a slightly differing axial localization along the kidney proximal tubule...
  18. ncbi request reprint Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway
    Tamara Ramadan
    Institute of Physiology and Centre for Integrative Human Physiology ZIHP, University of Zurich, Winterthurerstrasse, Zurich, Switzerland
    J Cell Physiol 206:771-9. 2006
    ..We propose that it, thereby, may supply parallel exchangers with recycling uptake substrates that could drive the efflux of other amino acids...
  19. ncbi request reprint Aromatic amino acid transporter AAT-9 of Caenorhabditis elegans localizes to neurons and muscle cells
    Emilija Veljkovic
    Institutes of Physiology and Zoology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Biol Chem 279:49268-73. 2004
    ..Taken together, the results show that AAT-9 is expressed in excitable cells of the nematode head and pharynx in which it may provide a pathway for aromatic amino acid transport...
  20. ncbi request reprint SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes
    Marija Zecevic
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Pflugers Arch 448:29-35. 2004
    ....
  21. doi request reprint Defective intestinal amino acid absorption in Ace2 null mice
    Dustin Singer
    Institute of Physiology, University of Zurich, Switzerland
    Am J Physiol Gastrointest Liver Physiol 303:G686-95. 2012
    ..In summary, mice lacking Ace2-dependent intestinal amino acid transport display no total niacin deficiency nor clear pellagra symptoms, even under a low-protein and low-niacin diet, despite gross amino acid homeostasis alterations...
  22. pmc Heterodimeric amino acid transporter glycoprotein domains determining functional subunit association
    Raffaella Franca
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Biochem J 388:435-43. 2005
    ....
  23. ncbi request reprint Crucial role of Asp408 in the proton translocation pathway of multidrug transporter AcrB: evidence from site-directed mutagenesis and carbodiimide labeling
    Markus A Seeger
    Institute of Physiology and Zurich Centre for Integrative Human Physiology ZIHP, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Biochemistry 48:5801-12. 2009
    ..This study provides evidence for a substantial role of membrane-located carboxylates as a central element of the proton translocation pathway in AcrB and other members of the RND superfamily...
  24. doi request reprint Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins
    Carsten A Wagner
    Institute of Physiology, Center for Integrative Human Physiology, Univ of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Am J Physiol Renal Physiol 294:F1373-80. 2008
    ..These adaptive changes in Romk(-/-) mice may help to limit renal Na(+) loss, and thereby, contribute to survival of these mice...
  25. doi request reprint Kidney amino acid transport
    Francois Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Pflugers Arch 458:53-60. 2009
    ..Thus, other transporters within the same membrane need to mediate the net efflux of exchange substrates, controlling thereby the net basolateral amino transport and thus the intracellular amino acid concentration...
  26. doi request reprint Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2
    Benjamin Oberfeld
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Am J Physiol Renal Physiol 301:F189-96. 2011
    ..Taken together, the data support the conclusion that Usp2-45 action on ENaC is promoted by various interactions, including through binding to Nedd4-2 that is suggested to position Usp2-45 favorably for ENaC deubiquitylation...
  27. ncbi request reprint Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters
    Emilija Veljkovic
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Biol Chem 279:7655-62. 2004
    ..Taken together, this study demonstrates that the heteromeric structure and the amino acid exchange function of HATs have been conserved throughout the evolution of nematodes to mammals...
  28. ncbi request reprint Regulation of renal amino acid transporters during metabolic acidosis
    Caroline Moret
    Institute of Physiology and Center for Integrative Human Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Am J Physiol Renal Physiol 292:F555-66. 2007
    ..Our results suggest that the selective regulation of SNAT3 and y(+)LAT1 expression may serve a major role in the renal adaptation to acid secretion and thus for systemic acid-base balance...
  29. doi request reprint Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency
    Julia Muller
    Leibniz Institute for Age Research Fritz Lipmann Institute J M, S M, L F, H H, Jena, Germany Department of Internal Medicine T J V, Erasmus Medical Center, Rotterdam, The Netherlands Laboratory of Comparative Endocrinology V M D, Biology Department, Katholieke Universiteit Leuven, Leuven, Belgium Department of Endocrinology and Metabolism A B, Academic Medical Center, Amsterdam, The Netherlands Institute of Physiology and Z├╝rich Center for Integrative Human Physiology L M, F V, University of Zurich, Zurich, Switzerland and Leibniz Institute for Environmental Medicine H H, Dusseldorf, Germany
    Endocrinology 155:315-25. 2014
    ..In summary, our data indicate that Mct10 indeed participates in tissue-specific TH transport and also contributes to the generation of the unusual serum TH profile characteristic for Mct8 deficiency. ..
  30. ncbi request reprint Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family
    L Mastroberardino
    Institute of Physiology, University of Zurich, Switzerland
    Nature 395:288-91. 1998
    ..The coexpression of h4F2hc is required for surface expression of these permease-related light chains, which belong to a new family of amino-acid transporters that form heterodimers with cell-surface glycoproteins...
  31. ncbi request reprint An amino acid transporter involved in gastric acid secretion
    Philipp Kirchhoff
    Institute of Physiology and Center for Integrative Human Physiology CIHP, University of Zurich, Winterthurerstr 190, 8057 Zurich, Switzerland
    Pflugers Arch 451:738-48. 2006
    ..These data suggest a novel role for heterodimeric amino acid transporters and may elucidate a pathway by which protein-rich diets stimulate gastric acid secretion...
  32. pmc Expression of heteromeric amino acid transporters along the murine intestine
    Mital H Dave
    Institute of Physiology, University of Zurich, Winterthurerstr 190, CH 8057 Zurich, Switzerland
    J Physiol 558:597-610. 2004
    ..Furthermore, strong expression of rBAT, b degrees (,+)AT and y(+)-LAT1 in the small intestine explains the reduced intestinal absorption of some amino acid in patients with cystinuria or lysinuric protein intolerance...
  33. ncbi request reprint Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK
    J Loffing
    Institute of Anatomy, , , Switzerland
    Am J Physiol Renal Physiol 280:F675-82. 2001
    ..Results from oocyte experiments suggest the hypothesis that a localized activation of SGK may play a role in the mediation of ENaC translocation...
  34. pmc The cataract and glucosuria associated monocarboxylate transporter MCT12 is a new creatine transporter
    Jeannette Abplanalp
    Institute of Medical Molecular Genetics, University of Zurich, Zurich, Switzerland
    Hum Mol Genet 22:3218-26. 2013
    ..We discuss the distinct, but possibly synergistic functions of the two creatine transporters. Our findings infer potential preventive power of creatine supplementation against the most prominent age-related vision impaired condition. ..
  35. ncbi request reprint Does kidney amino acid transport have something to do with blood pressure?
    Francois Verrey
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nephrol Dial Transplant 22:2449-51. 2007
  36. ncbi request reprint Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism
    Markus A Seeger
    Institute of Physiology and Zurich Centre for Integrative Human Physiology ZIHP, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Science 313:1295-8. 2006
    ..The structural data imply an alternating access mechanism and a novel peristaltic mode of drug transport by this type of transporter...
  37. ncbi request reprint Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation
    Panagiotis Fakitsas
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Am Soc Nephrol 18:1084-92. 2007
    ..A deubiquitylating enzyme that targets ENaC in vitro and thus may play a role in sodium transport regulation was identified within a series of new in vivo early aldosterone-regulated gene products...
  38. pmc Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family
    R Pfeiffer
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    EMBO J 18:49-57. 1999
    ....
  39. pmc Activation of system L heterodimeric amino acid exchangers by intracellular substrates
    Christian Meier
    Institute of Physiology and Institute of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    EMBO J 21:580-9. 2002
    ....
  40. ncbi request reprint Functional characterization of a NapA Na(+)/H(+) antiporter from Thermus thermophilus
    Esther M Furrer
    Institute of Physiology and Zurich Centre for Integrative Human Physiology ZIHP, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    FEBS Lett 581:572-8. 2007
    ..thermophilus resembles that of NhaA from E. coli, whereas in contrast to NhaA the T. thermophilus NapA antiporter is characterized by high Li(+)/H(+) antiport activity at acidic pH...
  41. ncbi request reprint Early aldosterone action: toward filling the gap between transcription and transport
    F Verrey
    Institute of Physiology, University of Zurich, CH 8057 Zurich, Switzerland
    Am J Physiol 277:F319-27. 1999
    ....
  42. ncbi request reprint Early aldosterone effects
    F Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Exp Nephrol 6:294-301. 1998
    ..The aim of this minireview is to describe briefly both the classical early and rapid nongenomic effects of aldosterone and to address the question whether nongenomic effects might play a role for the Na+ transport response...
  43. ncbi request reprint New glycoprotein-associated amino acid transporters
    F Verrey
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Membr Biol 172:181-92. 1999
    ..In this review, we focus on the animal members of the LAT cluster that form, together with some of the nematode members, the family of glycoprotein-associated amino acid transporters (gpaAT family)...
  44. ncbi request reprint Sodium reabsorption in aldosterone-sensitive distal nephron: news and contributions from genetically engineered animals
    F Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Curr Opin Nephrol Hypertens 10:39-47. 2001
    ....
  45. ncbi request reprint Short term effect of aldosterone on Na,K-ATPase cell surface expression in kidney collecting duct cells
    V Summa
    Institute of Physiology, , Winterthurerstrasse 190, , Switzerland
    J Biol Chem 276:47087-93. 2001
    ..Feraille, E., Kaissling, B., Asher, C., Rossier, B. C., Firestone, G. L., Pearce, D., and Verrey, F. (2001) Am. J. Physiol. 280, F675-F682) but also by coordinately acting on the basolateral cell surface expression of the Na,K-ATPase...
  46. ncbi request reprint Glycoprotein-associated amino acid exchangers: broadening the range of transport specificity
    F Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Pflugers Arch 440:503-12. 2000
    ....
  47. ncbi request reprint Pleiotropic action of aldosterone in epithelia mediated by transcription and post-transcription mechanisms
    F Verrey
    Institute of Physiology, University of Zurich, Switzerland
    Kidney Int 57:1277-82. 2000
    ..This suggests mechanisms for the escape from aldosterone action...
  48. pmc Specific amino acids inhibit food intake via the area postrema or vagal afferents
    Josua Jordi
    F Verrey Institute of Physiology, University of Zurich, Winterthurerstr 190, CH 8057 Zurich, Switzerland
    J Physiol 591:5611-21. 2013
    ..Overall, this study reveals novel amino acid-specific mechanisms for the control of food intake and of gastrointestinal function...
  49. pmc Luminal heterodimeric amino acid transporter defective in cystinuria
    R Pfeiffer
    Institute of Physiology, University of Zurich, CH 8057 Zurich, Switzerland
    Mol Biol Cell 10:4135-47. 1999
    ..These biochemical, transport, and localization characteristics as well as the chromosomal localization on 19q support the notion that the b(0,+)AT protein is the product of the gene defective in non-type I cystinuria...
  50. ncbi request reprint Mediators of aldosterone action in the renal tubule
    J Loffing
    Institute of Anatomy, , , Switzerland
    Curr Opin Nephrol Hypertens 10:667-75. 2001
    ..In view of the ongoing research, the question of how, and formally also whether, SGK1 acts on the epithelial sodium channel should be resolved in the near future...
  51. ncbi request reprint Identification of a new gene product (diphor-1) regulated by dietary phosphate
    M Custer
    Institute of Physiology, University of Zurich, Switzerland
    Am J Physiol 273:F801-6. 1997
    ..Further characterizations of diphor-1 will show whether diphor-1 is primarily or secondarily involved in the response to dietary Pi...
  52. ncbi request reprint Characterization of early aldosterone-induced RNAs identified in A6 kidney epithelia
    B Spindler
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Pflugers Arch 434:323-31. 1997
    ..These characteristics of RNA accumulation and their time courses suggest a possible role of one of these induced RNAs in the mediation of the early effect of aldosterone on Na transport...
  53. pmc Amino acids regulate transgene expression in MDCK cells
    Marta Torrente
    Institute of Physiology and Zurich Center of Integrative Human Physiology, University of Zurich, Zurich, Switzerland
    PLoS ONE 9:e96823. 2014
    ....
  54. ncbi request reprint Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain
    Victoria Makrides
    Institute of Physiology, University of Zurich, Switzerland
    Brain Res 1147:25-33. 2007
    ..Therefore, the results from animal experiments concerning BBB amino acid transport may not be transferable to humans...
  55. pmc Differential axial localization along the mouse brain vascular tree of luminal sodium-dependent glutamine transporters Snat1 and Snat3
    Nadine Ruderisch
    Institute of Physiology and Center for Integrative Human Physiology ZIHP, University of Zurich, Zurich, Switzerland
    J Cereb Blood Flow Metab 31:1637-47. 2011
    ..This differential expression of system A (Snat1) versus system N (Snat3) transporters suggests distinct roles for Snats in the cerebral vasculature and is consistent with Snat3 involvement in net transendothelial BBB AA transport...
  56. pmc Aldosterone modulates sodium kinetics of Na,K-ATPase containing an alpha 1 subunit in A6 kidney cell epithelia
    J Beron
    Institute of Physiology, University of Zurich, Switzerland
    Mol Biol Cell 6:261-71. 1995
    ..In the long term it produces an increase in the maximal transport capacity, which corresponds to the known increase in the number of Na pumps...
  57. ncbi request reprint Apical heterodimeric cystine and cationic amino acid transporter expressed in MDCK cells
    Christian Bauch
    Institute of Physiology, University of Zurich, CH 8057 Zurich, Switzerland
    Am J Physiol Renal Physiol 283:F181-9. 2002
    ....
  58. pmc Regulation of Na+ pump function by aldosterone is alpha-subunit isoform specific
    R Pfeiffer
    Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Physiol 516:647-55. 1999
    ..6. The fact that this early transcriptionally mediated activation of Na+ pumps by aldosterone is specific for pumps containing an alpha1 subunit should permit the identification in this subunit of structures involved in its regulation...
  59. ncbi request reprint Identification of a cDNA/protein leading to an increased Pi-uptake in Xenopus laevis oocytes
    F Norbis
    Institute of Physiology, University of Zurich, Switzerland
    J Membr Biol 156:19-24. 1997
    ..In conclusion, we have cloned from a rabbit small intestinal cDNA library a novel cDNA encoding a protein stimulating P(i)-uptake into Xenopus laevis oocytes, but which is not a P(i)-transporter itself...