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Affiliation: University of Lausanne
Location: Lausanne, Switzerland
Li S, Franken P, Vassalli A. Bidirectional and context-dependent changes in theta and gamma oscillatory brain activity in noradrenergic cell-specific Hypocretin/Orexin receptor 1-KO mice. Sci Rep. 2018;8:15474 pubmed publisher
..75-2.25 Hz), suggesting that HCRT-to-NA signalling regulates the slow-δ rebound characterizing sleep after stress-associated arousal. ..
Vassalli A, Franken P. Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need. Proc Natl Acad Sci U S A. 2017;114:E5464-E5473 pubmed publisher
..Hcrt loss in Hcrtko/ko mice causes impaired TDW maintenance in baseline wake and blunted ? power in SWS, reproducing, respectively, narcolepsy excessive daytime sleepiness and poor sleep quality. ..