Jurg Utzinger

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi request reprint Conquering schistosomiasis in China: the long march
    Jurg Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Acta Trop 96:69-96. 2005
  2. doi request reprint Schistosomiasis research in Africa: how the CONTRAST alliance made it happen
    Jurg Utzinger
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland University of Basel, P O Box, CH 4003 Basel, Switzerland Electronic address
    Acta Trop 128:182-95. 2013
  3. pmc Modelling the geographical distribution of soil-transmitted helminth infections in Bolivia
    Frédérique Chammartin
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Parasit Vectors 6:152. 2013
  4. pmc Frontiers of parasitology research in the People's Republic of China: infection, diagnosis, protection and surveillance
    Jun Hu Chen
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, People s Republic of China
    Parasit Vectors 5:221. 2012
  5. pmc Absence of dry season Plasmodium parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in preschool-aged children in Kaédi, southern Mauritania
    Sunkaru Touray
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P, O, Box, CH 4002, Basel, Switzerland
    Parasit Vectors 5:193. 2012
  6. pmc Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change
    Guo Jing Yang
    Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, People s Republic of China
    Malar J 11:426. 2012
  7. pmc Mapping malaria risk among children in Côte d'Ivoire using Bayesian geo-statistical models
    Giovanna Raso
    Département Environnement et Santé, Centre suisse de recherches scientifiques en Côte d Ivoire, BP 1303, Abidjan 01, Cote d Ivoire
    Malar J 11:160. 2012
  8. pmc Willingness to use a rapid diagnostic test for malaria in a rural area of central Côte d'Ivoire
    Colombe Coffie Comoé
    Département Environnement et Santé, Centre suisse de recherches scientifiques en Côte d Ivoire, Abidjan, Cote d Ivoire
    BMC Public Health 12:1089. 2012
  9. pmc Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) using an integrated multidisciplinary approach
    Stefanie Knopp
    Wolfson Wellcome Biomedical Laboratories, Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK
    BMC Public Health 12:930. 2012
  10. pmc Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests
    Sören L Becker
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    BMC Infect Dis 13:37. 2013

Detail Information

Publications151 found, 100 shown here

  1. ncbi request reprint Conquering schistosomiasis in China: the long march
    Jurg Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Acta Trop 96:69-96. 2005
    ..Issuing from the review is a set of recommendations, which might further consolidate current control activities, with the ultimate aim to eliminate schistosomiasis from the Chinese mainland...
  2. doi request reprint Schistosomiasis research in Africa: how the CONTRAST alliance made it happen
    Jurg Utzinger
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland University of Basel, P O Box, CH 4003 Basel, Switzerland Electronic address
    Acta Trop 128:182-95. 2013
    ..Finally, post-CONTRAST initiatives are discussed and a speculative viewpoint is given on how schistosomiasis control/elimination will have evolved over the next several years...
  3. pmc Modelling the geographical distribution of soil-transmitted helminth infections in Bolivia
    Frédérique Chammartin
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Parasit Vectors 6:152. 2013
    ..e. Ascaris lumbricoides, Trichuris trichiura, and hookworm) in Bolivia is among the highest in Latin America. However, the spatial distribution and burden of soil-transmitted helminthiasis are poorly documented...
  4. pmc Frontiers of parasitology research in the People's Republic of China: infection, diagnosis, protection and surveillance
    Jun Hu Chen
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, People s Republic of China
    Parasit Vectors 5:221. 2012
    ..R. China. Experiences and lessons learned can stimulate control and elimination efforts of parasitic diseases in other parts of the world...
  5. pmc Absence of dry season Plasmodium parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in preschool-aged children in Kaédi, southern Mauritania
    Sunkaru Touray
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P, O, Box, CH 4002, Basel, Switzerland
    Parasit Vectors 5:193. 2012
    ..g. acute respiratory infections and diarrhoea), new research is needed to better understand malaria transmission patterns in this region to improve adaptive, preventive and curative measures...
  6. pmc Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change
    Guo Jing Yang
    Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, People s Republic of China
    Malar J 11:426. 2012
    ....
  7. pmc Mapping malaria risk among children in Côte d'Ivoire using Bayesian geo-statistical models
    Giovanna Raso
    Département Environnement et Santé, Centre suisse de recherches scientifiques en Côte d Ivoire, BP 1303, Abidjan 01, Cote d Ivoire
    Malar J 11:160. 2012
    ..Risk maps are important to guide control interventions, and hence, the aim of this study was to predict the geographical distribution of malaria infection risk in children aged <16 years in Côte d'Ivoire at high spatial resolution...
  8. pmc Willingness to use a rapid diagnostic test for malaria in a rural area of central Côte d'Ivoire
    Colombe Coffie Comoé
    Département Environnement et Santé, Centre suisse de recherches scientifiques en Côte d Ivoire, Abidjan, Cote d Ivoire
    BMC Public Health 12:1089. 2012
    ..The aim of this study was to determine knowledge, attitudes, practices and beliefs in relation to RDTs for malaria in rural Côte d'Ivoire...
  9. pmc Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) using an integrated multidisciplinary approach
    Stefanie Knopp
    Wolfson Wellcome Biomedical Laboratories, Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK
    BMC Public Health 12:930. 2012
    ..Additionally, snail control and behaviour change interventions will be implemented in selected communities and the outcomes and impact measured in a randomized intervention trial...
  10. pmc Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests
    Sören L Becker
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    BMC Infect Dis 13:37. 2013
    ..We provide an overview of pathogens causing digestive disorders in the tropics and evaluate available reference tests...
  11. doi request reprint Neglected tropical diseases: diagnosis, clinical management, treatment and control
    Jurg Utzinger
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel and University of Basel, Switzerland
    Swiss Med Wkly 142:w13727. 2012
    ....
  12. pmc Efficacy of ICON® Maxx in the laboratory and against insecticide-resistant Anopheles gambiae in central Côte d'Ivoire
    Mirko S Winkler
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland
    Malar J 11:167. 2012
    ..In this study, the efficacy of ICON® Maxx (Syngenta) was evaluated under laboratory conditions and in an experimental hut trial in central Côte d'Ivoire, where Anopheles gambiae s.s. are resistant to pyrethroid insecticides...
  13. pmc Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni
    Jia V Li
    Section of Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK
    Parasit Vectors 4:179. 2011
    ..Here, we investigated the systems metabolic changes in the mouse upon S. mansoni infection by modeling the sequence of metabolic events in urine, plasma and faecal water...
  14. pmc Compensatory density feedback of Oncomelania hupensis populations in two different environmental settings in China
    Guo Jing Yang
    Jiangsu Institute of Parasitic Diseases, Meiyuan Yangxiang 117, Wuxi 214064, People s Republic of China
    Parasit Vectors 4:133. 2011
    ..We provide an empirical framework for discerning the relative contribution of intrinsic effects (density feedback) from other extrinsic drivers of snail population dynamics...
  15. pmc Modelling age-heterogeneous Schistosoma haematobium and S. mansoni survey data via alignment factors
    Nadine Schur
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P, O, Box, CH 4002 Basel, Switzerland
    Parasit Vectors 4:142. 2011
    ..However, data are often reported for non-standard age groups or entire study populations. Existing geostatistical models ignore either the age-dependence of the disease risk or omit surveys considered too heterogeneous...
  16. pmc No Paragonimus in high-risk groups in Côte d'Ivoire, but considerable prevalence of helminths and intestinal protozoon infections
    Sylvain G Traoré
    Laboratoire de Biotechnologie et Microbiologie des Aliments, UFR des Sciences et Technologies des Aliments, Université d Abobo Adjamé, Abidjan, Cote d Ivoire
    Parasit Vectors 4:96. 2011
    ..The disease is often confused with tuberculosis. Paragonimiasis is thought to be endemic in south-western Côte d'Ivoire...
  17. pmc The use of insecticide-treated nets for reducing malaria morbidity among children aged 6-59 months, in an area of high malaria transmission in central Côte d'Ivoire
    Benjamin G Koudou
    Vector Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Parasit Vectors 3:91. 2010
    ..abstract:..
  18. pmc Spatial epidemiology in zoonotic parasitic diseases: insights gained at the 1st International Symposium on Geospatial Health in Lijiang, China, 2007
    Xiao Nong Zhou
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, PR China
    Parasit Vectors 2:10. 2009
    ....
  19. pmc Malaria knowledge and long-lasting insecticidal net use in rural communities of central Côte d'Ivoire
    Allassane F Ouattara
    Département Environnement et Santé, Centre suisse de recherches scientifiques en Côte d Ivoire, 01 BP 1303, Abidjan 01, Cote d Ivoire
    Malar J 10:288. 2011
    ..The aim of this study was to determine factors that influence the use of long-lasting insecticidal nets (LLINs) in three rural communities of Côte d'Ivoire, two of which benefited from recent interventions...
  20. pmc Spatially-explicit risk profiling of Plasmodium falciparum infections at a small scale: a geostatistical modelling approach
    Kigbafori D Silué
    UFR Biosciences, Université de Cocody Abidjan, 22 BP 770, Abidjan 22, Cote d Ivoire
    Malar J 7:111. 2008
    ..Spatially-explicit risk profiling will play an important role in this endeavour. Patterns of Plasmodium falciparum infection prevalence were examined among schoolchildren in a highly malaria-endemic area...
  21. pmc Social and cultural aspects of 'malaria' and its control in central Côte d'Ivoire
    Clémence Essé
    Institut d Ethno Sociologie, Université de Cocody Abidjan, 01 BP V34, Abidjan 01, Cote d Ivoire
    Malar J 7:224. 2008
    ....
  22. pmc Spatial risk profiling of Plasmodium falciparum parasitaemia in a high endemicity area in Côte d'Ivoire
    Giovanna Raso
    Département Environnement et Santé, Centre Suisse de Recherches Scientifiques, Abidjan, Cote d Ivoire
    Malar J 8:252. 2009
    ....
  23. pmc Effect of an armed conflict on relative socioeconomic position of rural households: case study from western Côte d'Ivoire
    Thomas Fürst
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Emerg Themes Epidemiol 7:6. 2010
    ..In contrast, there is a paucity of quantitative studies about the socioeconomic consequences of armed conflict at the micro-level, i.e., noncommitted local households and civilians...
  24. pmc Comparison of two approaches for measuring household wealth via an asset-based index in rural and peri-urban settings of Hunan province, China
    Julie Balen
    Queensland Institute of Medical Research, P, O, Royal Brisbane Hospital, Brisbane 4029, Queensland, Australia
    Emerg Themes Epidemiol 7:7. 2010
    ..Our aim was to compare direct and proxy methods of estimating household wealth in a rural and a peri-urban setting of Hunan province, P.R. China...
  25. ncbi request reprint Geospatial health: the first five years
    Jurg Utzinger
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland
    Geospat Health 6:137-54. 2011
    ....
  26. doi request reprint Microscopic diagnosis of sodium acetate-acetic acid-formalin-fixed stool samples for helminths and intestinal protozoa: a comparison among European reference laboratories
    J Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Clin Microbiol Infect 16:267-73. 2010
    ..Continued external quality assessment and the establishment of a formal network of reference laboratories is necessary to further enhance both accuracy and uniformity in parasite diagnosis...
  27. pmc Self-rated quality of life and school performance in relation to helminth infections: case study from Yunnan, People's Republic of China
    Kathrin Ziegelbauer
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P, O, Box, CH 4002 Basel, Switzerland
    Parasit Vectors 3:61. 2010
    ..abstract:..
  28. doi request reprint From innovation to application: social-ecological context, diagnostics, drugs and integrated control of schistosomiasis
    Jurg Utzinger
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, PO Box, CH 4002 Basel, Switzerland
    Acta Trop 120:S121-37. 2011
    ..We discuss unresolved issues and emerging opportunities for integrated and sustainable control of schistosomiasis and conclude with a series of research needs...
  29. pmc Control of neglected tropical diseases: integrated chemotherapy and beyond
    Jurg Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Med 3:e112. 2006
  30. pmc Comparative cost assessment of the Kato-Katz and FLOTAC techniques for soil-transmitted helminth diagnosis in epidemiological surveys
    Benjamin Speich
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Parasit Vectors 3:71. 2010
    ..abstract:..
  31. ncbi request reprint Artemisinins for schistosomiasis and beyond
    Jurg Utzinger
    Swiss Tropical Institute, Department of Public Health and Epidemiology PO Box, CH 4002 Basel, Switzerland
    Curr Opin Investig Drugs 8:105-16. 2007
    ....
  32. ncbi request reprint Microhabitat preferences of Biomphalaria pfeifferi and Lymnaea natalensis in a natural and a man-made habitat in southeastern Tanzania
    J Utzinger
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Mem Inst Oswaldo Cruz 95:287-94. 2000
    ....
  33. pmc Schistosomiasis and neglected tropical diseases: towards integrated and sustainable control and a word of caution
    J Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Parasitology 136:1859-74. 2009
    ..Consequently, besides the environment, the prevailing demographic, health and social systems contexts need to be considered...
  34. pmc Rapid screening for Schistosoma mansoni in western Côte d'Ivoire using a simple school questionnaire
    J Utzinger
    Swiss Tropical Institute, Department of Public Health and Epidemiology, Basel, Switzerland
    Bull World Health Organ 78:389-98. 2000
    ..9%). The study, which is probably the largest of its kind ever undertaken in Africa, revealed a moderate diagnostic performance of questionnaires for identifying individuals and/or communities at high risk from S. mansoni...
  35. pmc Rapid re-infection with soil-transmitted helminths after triple-dose albendazole treatment of school-aged children in Yunnan, People's Republic of China
    Peiling Yap
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Am J Trop Med Hyg 89:23-31. 2013
    ..Rapid re-infection with A. lumbricoides was observed: the prevalence 4 and 6 months post-treatment was 75.8% and 83.8%, respectively. Re-infection with hookworm and T. trichiura was considerably slower...
  36. pmc Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs
    Stefanie Knopp
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 4:e681. 2010
    ..The purpose of this study was to determine patterns and risk factors of helminth infections and anemia in a rural and a peri-urban community of Zanzibar, Tanzania, in the context of national helminth control programs...
  37. pmc Diagnosis of soil-transmitted helminths in the era of preventive chemotherapy: effect of multiple stool sampling and use of different diagnostic techniques
    Stefanie Knopp
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 2:e331. 2008
    ..In this study, we focused on schoolchildren on Unguja Island, Zanzibar, an area where anthelminthic drugs have been repeatedly administered over the past decade...
  38. ncbi request reprint Multiple parasite infections and their relationship to self-reported morbidity in a community of rural Côte d'Ivoire
    Giovanna Raso
    Swiss Tropical Institute, PO Box, CH 4002 Basel, Switzerland
    Int J Epidemiol 33:1092-102. 2004
    ..We investigated the extent of polyparasitism and parasite associations, and related these findings to self-reported morbidity...
  39. ncbi request reprint Spatial distribution of soil-transmitted helminths, including Strongyloides stercoralis, among children in Zanzibar
    Stefanie Knopp
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Geospat Health 3:47-56. 2008
    ..Hence, additional measures, such as improving access to adequate sanitation and clean water and continued health education, are warranted to successfully control soil-transmitted helminthiasis in Zanzibar...
  40. pmc An integrated approach for risk profiling and spatial prediction of Schistosoma mansoni-hookworm coinfection
    Giovanna Raso
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Proc Natl Acad Sci U S A 103:6934-9. 2006
    ..More generally, this approach facilitates risk mapping and prediction of other parasite combinations and multiparasitism, and hence can guide integrated disease control programs in resource-constrained settings...
  41. pmc Occurrence of Strongyloides stercoralis in Yunnan Province, China, and comparison of diagnostic methods
    Peter Steinmann
    Department of Public Health, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 1:e75. 2007
    ..We studied the local occurrence of S. stercoralis in a village in Yunnan province, China, and comparatively assessed the performance of different diagnostic methods...
  42. pmc Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide
    Benjamin Speich
    Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, PO Box, CH 4002 Basel, Switzerland
    Parasit Vectors 6:3. 2013
    ..Since diagnosis of these parasites is difficult, prevalence data on intestinal protozoa is scarce...
  43. ncbi request reprint Spatial risk profiling of Schistosoma japonicum in Eryuan county, Yunnan province, China
    Peter Steinmann
    Department of Public Health and Epidemiology, Swiss Tropical Institute, PO Box, CH 4002 Basel, Switzerland
    Geospat Health 2:59-73. 2007
    ....
  44. pmc Interactions and potential implications of Plasmodium falciparum-hookworm coinfection in different age groups in south-central Côte d'Ivoire
    Aurélie A Righetti
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1889. 2012
    ..Understanding the complex interactions between these parasitic infections is of public health relevance considering that control measures targeting malaria and helminthiases are going to scale...
  45. doi request reprint Albendazole and mebendazole administered alone or in combination with ivermectin against Trichuris trichiura: a randomized controlled trial
    Stefanie Knopp
    Departments of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Clin Infect Dis 51:1420-8. 2010
    ..Single-dose albendazole and mebendazole show limited efficacy in the treatment of trichuriasis. The combination of albendazole with ivermectin improves efficacy, but a mebendazole-ivermectin combination has not been previously investigated...
  46. ncbi request reprint Urban agricultural land use and characterization of mosquito larval habitats in a medium-sized town of Côte d'Ivoire
    Barbara Matthys
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    J Vector Ecol 31:319-33. 2006
    ..Our findings have important bearings for the epidemiology and control of urban malaria in sub-Saharan Africa...
  47. ncbi request reprint Efficacy and side effects of praziquantel against Schistosoma mansoni in a community of western Côte d'Ivoire
    Giovanna Raso
    Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Trans R Soc Trop Med Hyg 98:18-27. 2004
    ..Our findings call for additional studies that rigorously evaluate the efficacy of praziquantel against different schistosome species in entire communities, using similarly sensitive diagnostic approaches as employed here...
  48. ncbi request reprint Urban farming and malaria risk factors in a medium-sized town in Cote d'Ivoire
    Barbara Matthys
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Am J Trop Med Hyg 75:1223-31. 2006
    ..Our findings indicate that specific crop systems and specific agricultural practices may increase the risk of malaria in urban settings of tropical Africa...
  49. ncbi request reprint Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both
    Xiao Shu-Hua
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Int J Parasitol 36:957-64. 2006
    ....
  50. pmc Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1917. 2012
    ..Since a pediatric formulation (e.g., syrup) is not available outside of Egypt, crushed praziquantel tablets are used, but the efficacy and safety of this treatment regimen is insufficiently studied...
  51. pmc Diagnostic accuracy of Kato-Katz and FLOTAC for assessing anthelmintic drug efficacy
    Stefanie Knopp
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1036. 2011
    ..We compared the diagnostic accuracy of the Kato-Katz and FLOTAC techniques in the frame of a drug efficacy trial...
  52. doi request reprint Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland
    Clin Infect Dis 50:1205-13. 2010
    ..Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have been performed...
  53. pmc Dynamics of Schistosoma haematobium egg output and associated infection parameters following treatment with praziquantel in school-aged children
    Katarina Stete
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Parasit Vectors 5:298. 2012
    ..Here, we determined the optimal time point for praziquantel efficacy assessment against Schistosoma haematobium and studied the dynamics of infection parameters following treatment...
  54. ncbi request reprint Risk factors for Schistosoma mansoni and hookworm in urban farming communities in western Côte d'Ivoire
    Barbara Matthys
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Trop Med Int Health 12:709-23. 2007
    ..To identify risk factors for Schistosoma mansoni and hookworm infections in urban farming communities, and to investigate small-scale spatial patterns of infection prevalence...
  55. doi request reprint A single FLOTAC is more sensitive than triplicate Kato-Katz for the diagnosis of low-intensity soil-transmitted helminth infections
    Stefanie Knopp
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Trans R Soc Trop Med Hyg 103:347-54. 2009
    ..50 for T. trichiura, but only 0.30 for hookworm. The high sensitivity of FLOTAC holds promise for patient management, monitoring soil-transmitted helminth transmission and endpoint(s) of control at the population level...
  56. pmc Accuracy of urine circulating cathodic antigen (CCA) test for Schistosoma mansoni diagnosis in different settings of Côte d'Ivoire
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1384. 2011
    ..We assessed the accuracy of a commercially available CCA cassette test (designated CCA-A) and an experimental formulation (CCA-B) for S. mansoni diagnosis...
  57. pmc Comparing diagnostic accuracy of Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC for Schistosoma mansoni and soil-transmitted helminths
    Dominik Glinz
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 4:e754. 2010
    ..Accurate diagnosis is crucial for patient management, drug efficacy evaluations, and monitoring of large-scale community-based control programs...
  58. pmc Accuracy of urine circulating cathodic antigen test for the diagnosis of Schistosoma mansoni in preschool-aged children before and after treatment
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 7:e2109. 2013
    ..We assessed the accuracy of a commercially available point-of-care circulating cathodic antigen (POC-CCA) cassette test for the diagnosis of S. mansoni in preschool-aged children before and after praziquantel administration...
  59. doi request reprint Dynamics of anemia in relation to parasitic infections, micronutrient status, and increasing age in South-Central Côte d'Ivoire
    Aurélie A Righetti
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Swittzerland
    J Infect Dis 207:1604-15. 2013
    ..There is a paucity of longitudinal studies monitoring the dynamics of anemia in relation to the aforementioned parameters...
  60. doi request reprint Effects of inflammation and Plasmodium falciparum infection on soluble transferrin receptor and plasma ferritin concentration in different age groups: a prospective longitudinal study in Côte d'Ivoire
    Aurélie A Righetti
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Am J Clin Nutr 97:1364-74. 2013
    ..Accurate biomarkers are needed to estimate the relative contribution of ID to anemia. Soluble transferrin receptor (sTfR) is thought to be unaffected by inflammation...
  61. pmc Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial
    Peter Steinmann
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS ONE 6:e25003. 2011
    ..We compared the efficacy of single-dose versus triple-dose treatment against hookworm and other STHs in a community-based randomized controlled trial in the People's Republic of China...
  62. pmc Tribendimidine and albendazole for treating soil-transmitted helminths, Strongyloides stercoralis and Taenia spp.: open-label randomized trial
    Peter Steinmann
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 2:e322. 2008
    ....
  63. doi request reprint FLOTAC: a promising technique for detecting helminth eggs in human faeces
    Stefanie Knopp
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Trans R Soc Trop Med Hyg 103:1190-4. 2009
    ..Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases...
  64. pmc Effect of schistosomiasis and soil-transmitted helminth infections on physical fitness of school children in Côte d'Ivoire
    Ivan Müller
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1239. 2011
    ..However, the effect of these diseases on physical fitness remains to be determined...
  65. pmc Comparison of the Flotac-400 dual technique and the formalin-ether concentration technique for diagnosis of human intestinal protozoon infection
    Sören L Becker
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    J Clin Microbiol 49:2183-90. 2011
    ....
  66. pmc Epidemiology of schistosomiasis in two high-risk communities of south Cote d'Ivoire with particular emphasis on pre-school-aged children
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Am J Trop Med Hyg 89:32-41. 2013
    ..In the current epidemiologic settings, more attention is warranted on pre-school-aged children and adolescents/adults for successful schistosomiasis control...
  67. pmc A new rapid diagnostic test for detection of anti-Schistosoma mansoni and anti-Schistosoma haematobium antibodies
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, PO Box, CH 4002 Basel, Switzerland
    Parasit Vectors 6:29. 2013
    ..Here, we assessed the diagnostic performance of the SmCTF-RDT for S. mansoni and S. haematobium infections by comparing it with microscopy for egg detection...
  68. pmc An in-depth analysis of a piece of shit: distribution of Schistosoma mansoni and hookworm eggs in human stool
    Stefanie J Krauth
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1969. 2012
    ..We studied the spatial distribution of Schistosoma mansoni and hookworm eggs in stool samples, the effect of homogenization, and determined egg counts over time in stool samples stored under different conditions...
  69. pmc Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis
    Kathrin Ziegelbauer
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Med 9:e1001162. 2012
    ..However, rapid reinfection of humans occurs after successful deworming, and therefore effective preventive measures are required to achieve public health goals with optimal efficiency and sustainability...
  70. doi request reprint High prevalence of Strongyloides stercoralis among school children in rural Côte d'Ivoire
    Dominik Glinz
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    J Parasitol 96:431-3. 2010
    ....
  71. doi request reprint Changing patterns of soil-transmitted helminthiases in Zanzibar in the context of national helminth control programs
    Stefanie Knopp
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Am J Trop Med Hyg 81:1071-8. 2009
    ..To consolidate achievements made, additional control measures such as health education and environmental sanitation are needed...
  72. ncbi request reprint Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Trans R Soc Trop Med Hyg 101:1219-22. 2007
    ..hepatica isolate, and hence these drugs might become useful in areas where triclabendazole resistance is common...
  73. pmc Evaluation of the in vivo activity of tribendimidine against Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis, and Opisthorchis viverrini
    Jennifer Keiser
    Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Antimicrob Agents Chemother 51:1096-8. 2007
    ..1% reduction of Clonorchis sinensis in rats. A 400-mg/kg dose of tribendimidine reduced Opisthorchis viverrini in hamsters by 95.7%. High doses of tribendimidine showed no activity against Schistosoma mansoni and Fasciola hepatica...
  74. ncbi request reprint Extensive multiparasitism in a village of Yunnan province, People's Republic of China, revealed by a suite of diagnostic methods
    Peter Steinmann
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Am J Trop Med Hyg 78:760-9. 2008
    ..Examination of 3 instead of 1 stool specimen increased the sensitivity of helminth diagnosis, most notably for hookworm. Intestinal multiparasitism is rampant in this rural part of Yunnan province and calls for control measures...
  75. ncbi request reprint Bayesian spatial risk prediction of Schistosoma mansoni infection in western Côte d'Ivoire using a remotely-sensed digital elevation model
    Christian Beck-Wörner
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Am J Trop Med Hyg 76:956-63. 2007
    ..mansoni, and is a powerful approach for risk profiling of other neglected tropical diseases that are pervasive in the developing world...
  76. ncbi request reprint Triclabendazole and its two main metabolites lack activity against Schistosoma mansoni in the mouse model
    Jennifer Keiser
    Swiss Tropical Institute, Basel, Switzerland
    Am J Trop Med Hyg 75:287-91. 2006
    ..mansoni strain. We conclude that triclabendazole and its main metabolites display weak and inconsistent schistosomicidal activities...
  77. ncbi request reprint Health impact assessment of industrial development projects: a spatio-temporal visualization
    Mirko S Winkler
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Geospat Health 6:299-301. 2012
    ..Methodological features are highlighted in the context of an iron ore development in a rural part of Africa...
  78. pmc Schistosomiasis, soil-transmitted helminthiasis, and sociodemographic factors influence quality of life of adults in Côte d'Ivoire
    Thomas Fürst
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1855. 2012
    ..However, disability weights, which capture the disability incurred by a typical patient of a certain condition, are fundamental to such burden calculation and their determination remains a widely debated issue...
  79. doi request reprint Fasciola hepatica: comparison of the sedimentation and FLOTAC techniques for the detection and quantification of faecal egg counts in rats
    Urs Duthaler
    Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland
    Exp Parasitol 126:161-6. 2010
    ..05). In view of the high sensitivity and efficiency, the FLOTAC technique holds promise for experimental work in the F. hepatica-rat model. Additional research is needed to determine the reasons for the observed differences in FECs...
  80. ncbi request reprint An approach to model the costs and effects of case management of Plasmodium falciparum malaria in sub-saharan Africa
    Fabrizio Tediosi
    Swiss Tropical Institute, Basel, Switzerland
    Am J Trop Med Hyg 75:90-103. 2006
    ..The current model is a first step towards useful predictions of the epidemiologic and economic consequences of introducing and/or scaling-up of malaria control interventions...
  81. doi request reprint Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration
    Alexandra U Scherrer
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Acta Trop 109:226-31. 2009
    ..This is justified on logistical grounds (i.e. collection of stool samples only once) and growing emphasis on integrating the control of schistosomiasis and soil-transmitted helminthiasis, including drug efficacy monitoring...
  82. doi request reprint Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland
    Parasitol Res 103:517-22. 2008
    ..Further studies are warranted to assess the potential of additional artemisinin derivatives and other peroxidic compounds for the treatment of Fasciola spp. infections in different ruminants...
  83. pmc Patients routinely report more symptoms to experienced field enumerators than physicians in rural Cote d'Ivoire
    Thomas Fürst
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Am J Trop Med Hyg 89:592-6. 2013
    ..Operational research should further explore best practices to obtain reliable medical histories in resource-constrained settings...
  84. ncbi request reprint Helminth infections and risk factor analysis among residents in Eryuan county, Yunnan province, China
    Peter Steinmann
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Acta Trop 104:38-51. 2007
    ..32, 95% CI=3.42-8.28, respectively). The opposite was found for T. trichiura (OR=0.31, 95% CI=0.14-0.70). Our findings can guide the design and spatial targeting of control interventions against helminth infections in Eryuan county...
  85. pmc Diagnosis, clinical features, and self-reported morbidity of Strongyloides stercoralis and hookworm infection in a Co-endemic setting
    Sören L Becker
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1292. 2011
    ..Moreover, clinical data on symptomatology and typical recognition patterns mainly originate from Western travel clinics...
  86. pmc Intestinal parasitic infections in schoolchildren in different settings of Côte d'Ivoire: effect of diagnostic approach and implications for control
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland
    Parasit Vectors 5:135. 2012
    ....
  87. pmc Soil-transmitted helminth infections and physical fitness in school-aged Bulang children in southwest China: results from a cross-sectional survey
    Peiling Yap
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box CH 4002, Basel, Switzerland
    Parasit Vectors 5:50. 2012
    ..R. China). Standardized, quality-controlled methods were employed to determine STH infections (Kato-Katz technique), haemoglobin levels, anthropometry (body weight and height) and physical fitness (20-m shuttle run test)...
  88. pmc Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial
    Benjamin Speich
    Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1685. 2012
    ..The currently used anthelmintic drugs, in single oral application, have low efficacy against Trichuris trichiura infection, and hence novel anthelmintic drugs are needed. Nitazoxanide has been suggested as potential drug candidate...
  89. pmc Questionnaire-based approach to assess schoolchildren's physical fitness and its potential role in exploring the putative impact of helminth and Plasmodium spp. infections in Côte d'Ivoire
    Thomas Fürst
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Parasit Vectors 4:116. 2011
    ..The previous practice of eliciting DWs by expert opinion has been challenged. More recent approaches employed quality of life (QoL) questionnaires to establish patient-based DWs, but results are ambiguous...
  90. ncbi request reprint The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica
    Jennifer Keiser
    Swiss Tropical Institute, CH 4002 Basel, Switzerland
    J Antimicrob Chemother 58:1193-7. 2006
    ..The trematocidal properties of a synthetic peroxide, 1,2,4-trioxolane (OZ78) were determined both in vivo and in vitro...
  91. pmc Combination chemotherapy against Clonorchis sinensis: experiments with artemether, artesunate, OZ78, praziquantel, and tribendimidine in a rat model
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Antimicrob Agents Chemother 53:3770-6. 2009
    ..sinensis is confirmed, and combination chemotherapy with praziquantel produces synergistic and antagonistic effects depending on the doses administered. Further preclinical investigations are warranted...
  92. doi request reprint Rare human infection with the trematode Echinochasmus japonicus in Lao PDR
    Somphou Sayasone
    Department of Public Health and Epidemiology, Swiss Tropical Institute, CH 4002 Basel, Switzerland
    Parasitol Int 58:106-9. 2009
    ..The frequent consumption of raw or insufficiently cooked freshwater fish and other aquatic products is the root cause of acquiring rare zoonotic infections such as E. japonicus...
  93. pmc Dynamics of socioeconomic risk factors for neglected tropical diseases and malaria in an armed conflict
    Thomas Fürst
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 3:e513. 2009
    ....
  94. pmc Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery
    Jasmina Saric
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 2:e254. 2008
    ....
  95. ncbi request reprint FLOTAC: a new sensitive technique for the diagnosis of hookworm infections in humans
    Jurg Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Trans R Soc Trop Med Hyg 102:84-90. 2008
    ..7 EPG) and ether concentration (5.7 EPG) methods. The FLOTAC method shows promise as an important new tool for individual hookworm diagnosis and for rigorous monitoring of helminth control programmes. [Clinical Trial No. ISRCTN21782274]...
  96. pmc Scope and Limits of an Anamnestic Questionnaire in a control-induced low-endemicity helminthiasis setting in South-Central Côte d'Ivoire
    Thomas Fürst
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS ONE 8:e64380. 2013
    ..However, as morbidity, infection, and transmission begin to decrease, more targeted treatment is likely to become more cost-effective, provided that comparatively cheap diagnostic methods with reasonable accuracy are available...
  97. ncbi request reprint Spatial distribution of Biomphalaria spp., the intermediate host snails of Schistosoma mansoni, in Brazil
    Ronaldo G C Scholte
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P O Box, CH 4002 Basel, Switzerland
    Geospat Health 6:S95-S101. 2012
    ..The generated risk maps of intermediate host snails might assist the national control programme for spatial targeting of control interventions and to ultimately move towards schistosomiasis elimination in Brazil...
  98. doi request reprint Opisthorchis viverrini: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Parasitol Res 102:771-6. 2008
    ..0%. In conclusion, our experiments confirm that tribendimidine possesses interesting trematocidal properties, which warrant additional investigations and provide further data for subsequent clinical trials...
  99. pmc Mefloquine--an aminoalcohol with promising antischistosomal properties in mice
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 3:e350. 2009
    ..Here, we report that the antimalarial drug mefloquine possesses promising antischistosomal properties in mice...
  100. doi request reprint Baseline health situation of communities affected by the Nam Theun 2 hydroelectric project in central Lao PDR and indicators for monitoring
    Tobias E Erlanger
    Swiss Tropical Institute, Basel, Switzerland
    Int J Environ Health Res 18:223-42. 2008
    ..8% (Nakai) and 54.9% of the individuals examined (Xe Bang Fai). Several indicators were extracted that can be utilised for monitoring changes in health, well-being and equity, as the project is implemented and operated...
  101. doi request reprint Clonorchicidal properties of the synthetic trioxolane OZ78
    Jennifer Keiser
    Swiss Tropical Institute, Basel, Switzerland
    J Parasitol 93:1208-13. 2007
    ..sinensis, respectively. SEM observations revealed tegumental surface alterations, including blebbing and sloughing. OZ78 emerges as a new compound with a broad spectrum of activity against major foodborne trematode infections...