Alan Tyndall

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi request reprint High-dose immunoablative therapy with hematopoietic stem cell support in the treatment of severe autoimmune disease: current status and future direction
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Intern Med 41:608-12. 2002
  2. doi request reprint Successes and failures of stem cell transplantation in autoimmune diseases
    Alan Tyndall
    University of Basel, Basel, Switzerland
    Hematology Am Soc Hematol Educ Program 2011:280-4. 2011
  3. ncbi request reprint Modern therapeutic strategies for autoimmune diseases
    Alan Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Spital, Burgfelderstrasse 101, 4012, Basel, Switzerland
    Curr Pharm Des 18:4508-12. 2012
  4. pmc Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group
    Chingching Foocharoen
    Department of Rheumatology, Basel University, Burgfelderstrasse 101, Basel 4012, Switzerland
    Arthritis Res Ther 14:R37. 2012
  5. doi request reprint Application of autologous stem cell transplantation in various adult and pediatric rheumatic diseases
    Alan Tyndall
    Department of Rheumatology, Felix Platter Spital, University of Basel, Basel, Switzerland
    Pediatr Res 71:433-8. 2012
  6. pmc Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future directions
    A Tyndall
    Department of Rheumatology, University Hospital Basle, Basle, Switzerland
    Clin Exp Immunol 141:1-9. 2005
  7. doi request reprint Future targets in the management of systemic sclerosis
    A Tyndall
    Department of Rheumatology, Felix Platter Hospital, Basel, Switzerland
    Rheumatology (Oxford) 48:iii49-53. 2009
  8. pmc Systemic sclerosis in Europe: first report from the EULAR Scleroderma Trials And Research (EUSTAR) group database
    A Tyndall
    Department of Rheumatology, Felix Platter Spital, CH 4012, Basel, Switzerland
    Ann Rheum Dis 64:1107. 2005
  9. ncbi request reprint Autologous hematopoietic stem cell transplantation for autoimmune diseases
    Alan Tyndall
    Department of Rheumatology, University Hospital, Basel, Switzerland
    Acta Haematol 114:239-47. 2005
  10. doi request reprint Cellular therapy of systemic lupus erythematosus
    A Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Hospital, 4012, Basel, Switzerland
    Lupus 18:387-93. 2009

Detail Information

Publications79

  1. ncbi request reprint High-dose immunoablative therapy with hematopoietic stem cell support in the treatment of severe autoimmune disease: current status and future direction
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Intern Med 41:608-12. 2002
    ..The concept of immunological "re-setting" has evolved, and needs to be confirmed by longer follow-up and the multicentre, international phase III randomized studies...
  2. doi request reprint Successes and failures of stem cell transplantation in autoimmune diseases
    Alan Tyndall
    University of Basel, Basel, Switzerland
    Hematology Am Soc Hematol Educ Program 2011:280-4. 2011
    ..Despite encouraging small phase 1/2 studies, no positive data from randomized, prospective studies are as yet available in the peer-reviewed literature...
  3. ncbi request reprint Modern therapeutic strategies for autoimmune diseases
    Alan Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Spital, Burgfelderstrasse 101, 4012, Basel, Switzerland
    Curr Pharm Des 18:4508-12. 2012
    ..Experimental strategies to achieve this include pre-emptive (preclinical) treatment before chronification is established, total immune ablation and immune "resetting" and autoantigen immunisation...
  4. pmc Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group
    Chingching Foocharoen
    Department of Rheumatology, Basel University, Burgfelderstrasse 101, Basel 4012, Switzerland
    Arthritis Res Ther 14:R37. 2012
    ..Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known...
  5. doi request reprint Application of autologous stem cell transplantation in various adult and pediatric rheumatic diseases
    Alan Tyndall
    Department of Rheumatology, Felix Platter Spital, University of Basel, Basel, Switzerland
    Pediatr Res 71:433-8. 2012
    ..Despite encouraging small phase I/II studies, no positive data from randomized, prospective studies are as yet available in the peer-reviewed literature...
  6. pmc Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future directions
    A Tyndall
    Department of Rheumatology, University Hospital Basle, Basle, Switzerland
    Clin Exp Immunol 141:1-9. 2005
    ..In those who relapsed, many responded to agents which pre transplant had been ineffective. The study of immune reconstitution and gene expression pre and post HSCT is being undertaken to further understand the mechanism of autoimmunity...
  7. doi request reprint Future targets in the management of systemic sclerosis
    A Tyndall
    Department of Rheumatology, Felix Platter Hospital, Basel, Switzerland
    Rheumatology (Oxford) 48:iii49-53. 2009
    ....
  8. pmc Systemic sclerosis in Europe: first report from the EULAR Scleroderma Trials And Research (EUSTAR) group database
    A Tyndall
    Department of Rheumatology, Felix Platter Spital, CH 4012, Basel, Switzerland
    Ann Rheum Dis 64:1107. 2005
  9. ncbi request reprint Autologous hematopoietic stem cell transplantation for autoimmune diseases
    Alan Tyndall
    Department of Rheumatology, University Hospital, Basel, Switzerland
    Acta Haematol 114:239-47. 2005
    ..Basic science programs are also being undertaken to study the immunological mechanisms underlying the clinical events observed...
  10. doi request reprint Cellular therapy of systemic lupus erythematosus
    A Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Hospital, 4012, Basel, Switzerland
    Lupus 18:387-93. 2009
    ..Mesenchymal stem cells are in an exploratory phase for the treatment of acute autoimmune disease including SLE. The principle is that they home to inflammed tissue and exert an antiinflammatory paracrine effect...
  11. doi request reprint Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks
    A Tyndall
    Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland
    Bone Marrow Transplant 43:821-8. 2009
    ..Multidisciplinary groups are collaborating to ensure maximal use of available resources to establish the place, if any, of MSC in the treatment of AD...
  12. ncbi request reprint Chronic GVHD as an autoimmune disease
    Alan Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Spital, Burfelderstrasse 101, 4012 Basel, Switzerland
    Best Pract Res Clin Haematol 21:281-9. 2008
    ....
  13. ncbi request reprint Why do we need noncommercial, investigator-initiated clinical trials?
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Nat Clin Pract Rheumatol 4:354-5. 2008
  14. pmc Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005
    Alan Tyndall
    Rheumatology, University Hospital Basel, Felix Platter Spital, Burgfelderstrasse 101, Basel, CH 4012, Switzerland
    Arthritis Res Ther 9:301. 2007
    ..This review summarizes the findings of a 1-day meeting devoted to the subject with the aim of coordinating efforts...
  15. ncbi request reprint Stem cells and rheumatology: update on adult stem cell therapy in autoimmune diseases
    Alan Tyndall
    University Hospital, Basle, Switzerland
    Arthritis Rheum 55:521-5. 2006
  16. ncbi request reprint [Rheumatoid arthritis--pearls and myths]
    A Tyndall
    Rheumatologische Universitätsklinik, Felix Platter Spital, Basel
    Ther Umsch 62:269-71. 2005
  17. ncbi request reprint Adult stem cell treatment of scleroderma
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Curr Opin Rheumatol 19:604-10. 2007
    ....
  18. ncbi request reprint Autologous hematopoietic stem cell transplantation for severe autoimmune disease with special reference to rheumatoid arthritis
    A Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    J Rheumatol Suppl 64:5-7. 2001
    ..Randomized, prospective controlled phase III trials have begun in SSc and will soon commence in RA and multiple sclerosis. More phase I and II data are required for systemic lupus erythematosus and juvenile idiopathic arthritis...
  19. ncbi request reprint News in autoimmune disease
    A Tyndall
    Department of Rheumatology, University of Basel Kantonsspital
    Schweiz Med Wochenschr 130:113-8. 2000
    ..We must not forget the aim of improving quality of life for our patients, and not just improvement of immunological laboratory parameters...
  20. ncbi request reprint Haematopoietic stem cell transplantation for the treatment of systemic sclerosis and other autoimmune disorders
    Alan Tyndall
    Department of Rheumatology, University of Basle, Felix Platter Spital, CH 4012, Basle, Switzerland
    Expert Opin Biol Ther 3:1041-9. 2003
    ..It is hypothesised that this results in fewer autoinflammatory and unwanted stimulatory signals to other systems such as vascular endothelium and fibroblasts, and these mechanisms are currently under study...
  21. pmc Immune ablation and stem-cell therapy in autoimmune disease. Clinical experience
    A Tyndall
    Department of Rheumatology, University of Basel, Basel, Switzerland
    Arthritis Res 2:276-80. 2000
    ..No one regimen was clearly superior to another, with a trend toward more infectious complications with more intense regimens. Prospective, controlled randomized trials are indicated and being planned...
  22. ncbi request reprint Immunoablation and haemopoietic stem cell transplantation for severe autoimmune disease with special reference to systemic lupus erythematosus
    A Tyndall
    University Department of Rheumatology, Felix Platter Spital, Burgfelderstrasses 101, Basal 4012, Switzerland
    Lupus 10:214-5. 2001
    ..Randomised, prospective controlled phase III trials are desired, but by consensus, more phase I and II data is required to plan the optimal protocol...
  23. pmc Haemopoietic stem cell transplantation in the treatment of severe autoimmune diseases 2000
    A Tyndall
    Department of Rheumatology, University Hospital, Basel, Switzerland
    Ann Rheum Dis 60:702-7. 2001
    ..Further phase I and II data are required in SLE, JIA, and vasculitis. The need for continuing collection of all cases after mobilisation by the standardised EBMT and IBMTR data forms was emphasised...
  24. doi request reprint The survey on cellular and engineered tissue therapies in Europe in 2010
    Ivan Martin
    Department of Surgery and of Biomedicine, University Hospital Basel, Basel, Switzerland
    Tissue Eng Part A 18:2268-79. 2012
    ..This year's edition specifically discusses scientific, clinical, regulatory, and commercial aspects related to the use of cell therapy for the repair of cartilage defects...
  25. doi request reprint Adult stem cell transplantation in autoimmune disease
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Curr Opin Hematol 16:285-91. 2009
    ..In addition, the newly evolving field of mesenchymal stem cell therapy of autoimmune disease is introduced...
  26. ncbi request reprint Stem cells in the treatment of inflammatory arthritis
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Best Pract Res Clin Rheumatol 24:565-74. 2010
    ....
  27. pmc Late altered organ function in very long-term survivors after allogeneic hematopoietic stem cell transplantation: a paired comparison with their HLA-identical sibling donor
    Alicia Rovo
    Department of Hematology, University Hospital of Basel, Basel, Switzerland
    Haematologica 96:150-5. 2011
    ..The study objective was to assess health status of very long-term survivors in comparison with their respective human leukocyte antigen-identical sibling donors...
  28. pmc Haematopoietic stem cell transplantation for vasculitis including Behcet's disease and polychondritis: a retrospective analysis of patients recorded in the European Bone Marrow Transplantation and European League Against Rheumatism databases and a review
    Thomas Daikeler
    Department of Rheumatology, University of Basle, Petersgraben 4, CH 4031 Basle, Switzerland
    Ann Rheum Dis 66:202-7. 2007
    ..To evaluate the feasibility of haematopoietic stem cell transplantation (HSCT) in vasculitis...
  29. ncbi request reprint The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis
    Martin Fuchs
    Institute of Nuclear Medicine, University Hospital, Petersgraben 4, 4031 Basel, Switzerland
    Eur J Nucl Med Mol Imaging 39:344-53. 2012
    ..We aimed to assess the impact of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) on the management of patients with suspected large vessel vasculitis...
  30. pmc The survey on cellular and engineered tissue therapies in Europe in 2009
    Ivan Martin
    Department of Surgery, University Hospital Basel, Basel, Switzerland
    Tissue Eng Part A 17:2221-30. 2011
    ..This year's edition specifically describes and discusses the use of MSC for the treatment of autoimmune diseases, due to the scientific, clinical, and economical implications of this topic...
  31. ncbi request reprint The EULAR Scleroderma Trials and Research Group (EUSTAR): an international framework for accelerating scleroderma research
    Alan Tyndall
    Department of Rheumatology, University of Basel, Basel, Switzerland
    Curr Opin Rheumatol 20:703-6. 2008
    ....
  32. ncbi request reprint Adult stem cells in the treatment of autoimmune diseases
    J M van Laar
    Department of Rheumatology, University of Basel, Felix Platter Spital, Burgfelderstrasse 101, Basel 4012, Switzerland
    Rheumatology (Oxford) 45:1187-93. 2006
    ..Such cells are immune privileged and apparently of low toxicity. Further characterization of these cells and consideration of their possible clinical application in AD is underway...
  33. pmc The survey on cellular and engineered tissue therapies in Europe in 2011
    Ivan Martin
    1 Department of Surgery, University Hospital Basel, University of Basel, Basel, Switzerland
    Tissue Eng Part A 20:842-53. 2014
    ..The data are compared with those collected since 2008 to identify trends in the field. This year's edition specifically focuses on cardiac cell therapy. ..
  34. ncbi request reprint Autoimmunity following haematopoietic stem-cell transplantation
    Thomas Daikeler
    Department of Rheumatology, University of Basel, University Hospital Basel, Petersgraben 4, CH 4058 Basel, Switzerland
    Best Pract Res Clin Haematol 20:349-60. 2007
    ..Prospective data for a better understanding of autoimmunity and 'altered' immunity after stem-cell transplantation are needed...
  35. ncbi request reprint Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party
    Thomas Daikeler
    Department of Rheumatology, University Hospital Basel, Basel, Switzerland
    Blood 118:1693-8. 2011
    ..This European multicenter study underlines the need for careful management and follow-up for secondary AD after HSCT...
  36. ncbi request reprint Cellular therapy of systemic sclerosis
    Jacob M van Laar
    Department of Rheumatology, Felix Platter Spital, University of Basel, Burgfelderstrasse 101, Basel 4012 Switzerland
    Curr Rheumatol Rep 10:189-94. 2008
    ..Therapies involving mesenchymal stromal cells are currently being explored in clinical settings because of their anti-inflammatory and tissue regenerative properties and their favorable risk/benefit ratio...
  37. doi request reprint Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated by interleukins 2, 7 and 15
    C Bocelli-Tyndall
    Institute of Surgical Research and Hospital Management and Department of Biomedicine, University Hospital Basel, Basel, Switzerland
    Ann Rheum Dis 68:1352-9. 2009
    ....
  38. doi request reprint Geographical variation of disease manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials and Research (EUSTAR) group database
    U A Walker
    Felix Platter Spital, Basel, Switzerland
    Ann Rheum Dis 68:856-62. 2009
    ..The aetiology is unknown. Genetic and environmental susceptibility factors have been implicated. It is unknown whether disease presentation varies within Europe...
  39. doi request reprint Allogeneic hematopoietic SCT for patients with autoimmune diseases
    T Daikeler
    Department of Rheumatology, University of Basel, University Hospital, Basel CH 4031, Switzerland
    Bone Marrow Transplant 44:27-33. 2009
    ..However, allogeneic HSCT can induce remission in patients suffering from refractory AD. These data provide the basis for carefully conducted prospective trials...
  40. doi request reprint Erectile dysfunction in systemic sclerosis
    U A Walker
    Department of Rheumatology, Basel University, Basel, Switzerland
    Ann Rheum Dis 68:1083-5. 2009
    ..When intracavernous injections of prostaglandin E1 (alprostadil) are ineffective, the implantation of a penile prosthesis may be considered. Complex treatment options may require the involvement of urology...
  41. ncbi request reprint Rheumatic conditions in human immunodeficiency virus infection
    U A Walker
    Department of Rheumatology, Basel University, Basel, Switzerland
    Rheumatology (Oxford) 47:952-9. 2008
    ..Thus, rheumatic diseases and asymptomatic immune phenomena remain prevalent in HIV-infected persons even after the widespread implementation of highly active anti-retroviral therapy...
  42. ncbi request reprint Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro
    C Bocelli-Tyndall
    Department of Rheumatology, University of Basel, Basel, Switzerland
    Rheumatology (Oxford) 46:403-8. 2007
    ....
  43. pmc Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database
    U A Walker
    Department of Rheumatology, Basle University, Felix Platter Spital, Burgfelderstrasse 101, Basel 4012, Switzerland
    Ann Rheum Dis 66:754-63. 2007
    ..In order to better understand the vascular, immunological and fibrotic processes of SSc and to guide its treatment, the EULAR Scleroderma Trials And Research (EUSTAR) group was formed in June 2004...
  44. doi request reprint Fibroblast growth factor 2 and platelet-derived growth factor, but not platelet lysate, induce proliferation-dependent, functional class II major histocompatibility complex antigen in human mesenchymal stem cells
    Chiara Bocelli-Tyndall
    University Hospital Basel and University of Basel, Basel, Switzerland
    Arthritis Rheum 62:3815-25. 2010
    ....
  45. doi request reprint Vascular involvement in patients with giant cell arteritis determined by duplex sonography of 2x11 arterial regions
    Markus Aschwanden
    Department of Rheumatology, University Hospital Basel, Petersgraben 4, Basel CH 4031, Switzerland
    Ann Rheum Dis 69:1356-9. 2010
    ..To define the specificity and extent of duplex sonography (DS) findings suggestive of vessel wall inflammation in patients with giant cell arteritis (GCA)...
  46. ncbi request reprint Autologous hemopoietic stem cell transplantation in severe rheumatoid arthritis: a report from the EBMT and ABMTR
    John A Snowden
    Department of Rheumatology, Felix Platter Spital, University of Basel, Basel, Switzerland
    J Rheumatol 31:482-8. 2004
    ..To date, published reports have been individual cases or series containing small numbers. This study combined the worldwide experience in a single analysis...
  47. ncbi request reprint [Pericardial effusion in a 21-year-old employee]
    St Wiggli
    Universitätsklinik Rheumatologie, Felix Platter Spital, Basel
    Praxis (Bern 1994) 95:419-21. 2006
  48. ncbi request reprint Autologous hematopoietic stem cell transplantation for autoimmune diseases
    A Gratwohl
    University Hospital, Basel, Switzerland
    Bone Marrow Transplant 35:869-79. 2005
    ..81 (0.96-3.42)); low intensity, RR2.34 (1.074-5.11)). These data from the collective EBMT experience support the hypothesis that autologous HSCT can alter disease progression in severe autoimmune disease...
  49. ncbi request reprint Haematopoetic stem cell transplantation for refractory autoimmune cytopenia
    J R Passweg
    Basel University Hospitals, Basel, Switzerland
    Br J Haematol 125:749-55. 2004
    ..Autologous and allogeneic HSCT may induce a response in a subset of patients with autoimmune cytopenia of long duration albeit at the price of considerable toxicity...
  50. ncbi request reprint A survey on cellular and engineered tissue therapies in europe in 2008
    Ivan Martin
    Department of Surgery and of Biomedicine, University Hospital, Basel, Switzerland
    Tissue Eng Part A 16:2419-27. 2010
    ..This data collection platform is expected to capture and foresee trends for novel cellular therapies in Europe, and warrants further consolidation and extension...
  51. ncbi request reprint [Hematopoietic stem cell transplantations in treatment of autoimmune diseases]
    A Gratwohl
    Department Innere Medizin Kantonsspital, Basel, Switzerland
    Z Rheumatol 56:173-7. 1997
    ..Clear clinical data are still missing. Preliminary data are promising and protocols for prospective studies are being prepared. They should allow a better evaluation of the procedures in a few years from now...
  52. ncbi request reprint Autologous stem cell transplantation of treatment-resistant systemic vasculitis--a single center experience and review of the literature
    I Kotter
    University Hospital, Department of Internal Medicine II Oncology, Hematology, Immunology, Rheumatology, Pulmology, Tubingen, Germany
    Clin Nephrol 64:485-9. 2005
    ..We intended to analyze the effects of autoPBSCT in patients with treatment-resistant systemic vasculitis by analyzing the outcome of 4 patients from our own hospital, and comparing them to cases reported in the literature...
  53. ncbi request reprint Serious bacterial infections in patients with rheumatoid arthritis under anti-TNF-alpha therapy
    S Kroesen
    Department of Rheumatology, University Hospital, Basel, Switzerland
    Rheumatology (Oxford) 42:617-21. 2003
    ..Our purpose was to assess the incidence and nature of severe infections in our RA patients under anti-TNF-alpha therapy...
  54. doi request reprint A comparison between ((3)H)-thymidine incorporation and isothermal microcalorimetry for the assessment of antigen-induced lymphocyte proliferation
    C Murigande
    Department of Rheumatology, Felix Platter Spital, Basel, Switzerland
    Immunol Invest 38:67-75. 2009
    ..Our study suggests that IMC measurements, despite the advantages of simplicity, on-line recording of metabolic activity and no use of radioactivity, may be limited to monitoring mitogen-induced lymphocyte proliferation...
  55. ncbi request reprint Systemic sclerosis without antinuclear antibodies or Raynaud's phenomenon: a multicentre study in the prospective EULAR Scleroderma Trials and Research (EUSTAR) database
    Daniel Schneeberger
    Department of Rheumatology, Basel University, Felix Platter Spital, Basel, Switzerland
    Rheumatology (Oxford) 52:560-7. 2013
    ..To assess patients with SSc who present without circulating ANAs or RP...
  56. pmc Multisegmental spondylitis due to Tropheryma whipplei: case report
    David Spoerl
    Department of Rheumatology, University of Basel, Felix Platter Spital, Basel, Switzerland
    Orphanet J Rare Dis 4:13. 2009
    ..In this clinical setting, routine PCR for Tropheryma whipplei from vertebral biopsies is recommended...
  57. ncbi request reprint Increased concentrations of antibody-bound circulatory cell-free DNA in rheumatoid arthritis
    Xiao Yan Zhong
    Laboratory for Prenatal Medicine, University Women s Hospital, Department of Research, University Hospital Basel, Basel, Switzerland
    Clin Chem 53:1609-14. 2007
    ..Evidence from in vitro and animal experiments suggests that DNA may play a role in the pathogenesis of rheumatoid arthritis (RA)...
  58. ncbi request reprint Bone marrow histology in a patient with fever of unknown origin
    Andreas Holbro
    Department of Internal Medecine, University Hospital Basel, Basel, Switzerland
    J Rheumatol 35:530-1. 2008
  59. ncbi request reprint Human articular chondrocytes suppress in vitro proliferation of anti-CD3 activated peripheral blood mononuclear cells
    Chiara Bocelli-Tyndall
    Department of Rheumatology, University of Basel, Felix Plattel Spital, Burgfelderstrasse 101, 4012 Basel, Switzerland
    J Cell Physiol 209:732-4. 2006
    ..To investigate whether mature human articular chondrocytes (AC) exhibit an antiproliferative effect on activated peripheral blood mononuclear cells (PBMC) and to compare this effect with other cells of mesenchymal origin...
  60. doi request reprint Sclerosing skin disorders in association with multiple sclerosis. Coincidence, underlying autoimmune pathology or interferon induced?
    T Hugle
    Felix Platter Spital, Basel University Department of Rheumatology, Switzerland
    Ann Rheum Dis 68:47-50. 2009
    ..To describe and analyse the manifestation of sclerosing skin disorders in patients with multiple sclerosis (MS)...
  61. ncbi request reprint Serum procalcitonin for discrimination between septic and non-septic arthritis
    T Hugle
    Department of Rheumatology, University Hospital Basel, Switzerland
    Clin Exp Rheumatol 26:453-6. 2008
    ..Early differentiation between septic and non-septic arthritis is difficult. A previous study showed promising diagnostic accuracy of serum Procalcitonin (PCT) in septic arthritis, limited by a low sensitive PCT test kit...
  62. ncbi request reprint Discriminatory ability of quantitative ultrasound parameters and bone mineral density in a population-based sample of postmenopausal women with vertebral fractures: results of the Basel Osteoporosis Study
    F Hartl
    Department of Rheumatology, Felix Platter Hospital, University of Basel, Switzerland
    J Bone Miner Res 17:321-30. 2002
    ..However, the performance of QUS measurements is at least comparable with DXA measurements in identifying subjects with multiple vertebral fractures randomly selected from the population...
  63. ncbi request reprint Tenofovir-induced osteomalacia
    D P Wanner
    Department of Rheumatology, Basle University, Basel, Switzerland
    Clin Exp Rheumatol 27:1001-3. 2009
    ..Awareness is needed to link the typically prolonged onset of clinical symptoms with TDF exposure and then establish the correct diagnosis...
  64. ncbi request reprint Focal myositis of the iliopsoas muscle--a benign pseudotumour: ultrasound appearance in correlation with CT and MRI
    A Hoffmann
    Department of Radiology, University Hospital Basel, Switzerland
    Ultraschall Med 27:180-4. 2006
    ..Focal myositis of the iliopsoas muscle is a rare condition. A case is presented, emphasizing the value of ultrasound for detection, localisation, image-guided biopsy and follow-up in correlation with CT and MRI findings...
  65. ncbi request reprint [Spondylodiscitis without fever: a diagnostic challenge]
    J Luthy
    Rheumatologische Universitätsklinik, Felix Platter Spital und Universitätsspital, Basel
    Dtsch Med Wochenschr 133:1725-9. 2008
    ..EXAMINATIONS, DIAGNOSIS: In all three patients the MRI of the affected vertebral column was consistent with vertebral osteomyelitis. Microbiological diagnosis was made by bone biopsy in all patients and by blood cultures in two of them...
  66. ncbi request reprint Autologous stem cell transplantation in autoimmune diseases
    Jakob Passweg
    Division of Hematology, University Hospital Geneva, Geneva, Switzerland
    Semin Hematol 44:278-85. 2007
    ....
  67. ncbi request reprint Allogeneic bone marrow transplantation for autoimmune disease--the jury is still out
    Alan Tyndall
    J Rheumatol 33:644-6. 2006
  68. ncbi request reprint Intense immunosuppression and stem-cell transplantation for patients with severe rheumatic autoimmune disease: a review
    Jacob M van Laar
    Department of Rheumatology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Cancer Control 10:57-65. 2003
    ....
  69. ncbi request reprint Target populations in allogeneic hematopoietic cell transplantation for autoimmune diseases--a workshop accompanying: cellular therapy for treatment of autoimmune diseases, basic science and clinical studies, including new developments in hematopoietic an
    Linda M Griffith
    Biol Blood Marrow Transplant 12:688-90. 2006
  70. ncbi request reprint Scleroderma lung: pathogenesis, evaluation and current therapy
    Jacob M van Laar
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    Drugs 67:985-96. 2007
    ..Uncontrolled studies have suggested that these therapies also have an impact on survival, but controlled studies with a long follow-up are needed to corroborate this point...
  71. doi request reprint Physical and not mental health is impaired in very long-term survivors after HSCT compared with their respective donors: a paired analysis
    Alicia Rovo
    Blood 111:1740-1. 2008
  72. pmc Cell therapy for autoimmune diseases
    Francesco Dazzi
    Stem Cell Biology Section, Kennedy Institute of Rheumatology, Imperial College Faculty of Medicine, London, UK
    Arthritis Res Ther 9:206. 2007
    ..All of these potential resources clearly need to be investigated at the preclinical level but support a great deal of enthusiasm for cell therapy of autoimmune diseases...
  73. ncbi request reprint The use of high dose immunoablative therapy with hematopoietic stem cell support therapy in the treatment of severe autoimmune diseases
    Alan Tyndall
    Int J Hematol 76:218-22. 2002
  74. ncbi request reprint Hematopoietic stem cell transplantation in autoimmune diseases: algorithm for cardiovascular assessment
    Irene Miniati
    Division Medicine I and Rheumatology, Department of Medicine and Surgery, University of Florence, Viale Pieraccini 18, 50139 Florence, Italy
    Herz 32:43-50. 2007
    ..The aim is to optimize cardiac status in order to allow intense immunosuppressive treatments...
  75. ncbi request reprint Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha
    Carlo Chizzolini
    Division of Immunologya and Allergy, Geneva University Hospital, Geneva, Switzerland
    Arthritis Rheum 48:2593-604. 2003
    ....
  76. doi request reprint Rheumatology gone global
    Daniel H Solomon
    Arthritis Rheum 59:1369-70. 2008
  77. ncbi request reprint Autologous stem cell transplantation for systemic lupus erythematosus
    David Jayne
    Department of Medicine, Addenbrooke s Hospital, Cambridge, UK
    Lupus 13:168-76. 2004
    ..The safety of this procedure is likely to be improved by patient selection and choice of conditioning regimen. The return of disease activity in one-third of patients might be reduced by long-term immunosuppressive therapy post-ASCT...
  78. doi request reprint Rheumatology gone global
    Daniel H Solomon
    Ann Rheum Dis 67:1357. 2008
  79. ncbi request reprint Feasibility of allogeneic hematopoietic stem cell transplantation for autoimmune disease: position statement from a National Institute of Allergy and Infectious Diseases and National Cancer Institute-Sponsored International Workshop, Bethesda, MD, March 1
    Linda M Griffith
    Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Biol Blood Marrow Transplant 11:862-70. 2005