M R Tramer

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Magnesium as an adjuvant to postoperative analgesia: a systematic review of randomized trials
    Christopher Lysakowski
    Division of Anesthesiology, Department Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 104:1532-9, table of contents. 2007
  2. pmc More insight into the fate of biomedical meeting abstracts: a systematic review
    Erik von Elm
    Centre for Evidence Based Perioperative Medicine, Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland
    BMC Med Res Methodol 3:12. 2003
  3. pmc Mortality with upper gastrointestinal bleeding and perforation: effects of time and NSAID use
    Sebastian Straube
    Department of Occupational and Social Medicine, University of Gottingen, Gottingen, Germany
    BMC Gastroenterol 9:41. 2009
  4. ncbi request reprint Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials
    M R Tramer
    Nuffield Department of Anaesthetics, The Churchill, and Oxford Radcliffe Hospital, United Kingdom
    Anesthesiology 87:1277-89. 1997
  5. ncbi request reprint [Prevention and treatment of postoperative nausea and vomiting in children. An evidence-based approach]
    M R Tramer
    Service d anesthésiologie, Hopitaux Universitaires de Geneve, Geneve, Switzerland
    Ann Fr Anesth Reanim 26:529-34. 2007
  6. ncbi request reprint [Postoperative nausea and vomiting]
    M R Tramer
    Service d anesthésiologie, Département APSI, Hopitaux Universitaires de Geneve, 1211 Geneve 14, Schweiz
    Anaesthesist 56:679-85. 2007
  7. ncbi request reprint An evaluation of a single dose of magnesium to supplement analgesia after ambulatory surgery: randomized controlled trial
    Martin R Tramer
    Division of Anesthesiology, Department Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 104:1374-9, table of contents. 2007
  8. pmc Pharmacological prevention of serious anaphylactic reactions due to iodinated contrast media: systematic review
    Martin R Tramer
    Division of Anaesthesiology, Geneva University Hospitals, CH 1211 Geneva, Switzerland
    BMJ 333:675. 2006
  9. ncbi request reprint [The pharmacology of PONV control: prevention or treatment?]
    M R Tramer
    Division Anästhesie, Universitatskliniken, CH 1211 Genf 14, Schweiz
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:493-7. 2005
  10. ncbi request reprint [Meta-analysis. A meaningful tool for evidence-based (intensive) medicine]
    M R Tramer
    Division d Anesthésiologie, Departement Anesthesiologie, Pharmacologie et Soins Intensifs Chirurgicaux, Hopitaux Universitaires de Geneve, Switzerland
    Anaesthesist 52:S5-6. 2003

Detail Information

Publications58

  1. ncbi request reprint Magnesium as an adjuvant to postoperative analgesia: a systematic review of randomized trials
    Christopher Lysakowski
    Division of Anesthesiology, Department Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 104:1532-9, table of contents. 2007
    ..Randomized trials have reached different conclusions as to whether magnesium is a useful adjuvant to postoperative analgesia...
  2. pmc More insight into the fate of biomedical meeting abstracts: a systematic review
    Erik von Elm
    Centre for Evidence Based Perioperative Medicine, Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland
    BMC Med Res Methodol 3:12. 2003
    ..We set out to estimate the proportion of abstracts submitted to meetings that are eventually published as full reports, and to explore factors that are associated with meeting acceptance and successful publication...
  3. pmc Mortality with upper gastrointestinal bleeding and perforation: effects of time and NSAID use
    Sebastian Straube
    Department of Occupational and Social Medicine, University of Gottingen, Gottingen, Germany
    BMC Gastroenterol 9:41. 2009
    ..Better treatment is likely to have reduced mortality. An estimate of mortality is helpful in explaining to patients the risks of therapy, especially with NSAIDs...
  4. ncbi request reprint Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials
    M R Tramer
    Nuffield Department of Anaesthetics, The Churchill, and Oxford Radcliffe Hospital, United Kingdom
    Anesthesiology 87:1277-89. 1997
    ..The authors reviewed efficacy and safety data for ondansetron for preventing postoperative nausea and vomiting (PONV)...
  5. ncbi request reprint [Prevention and treatment of postoperative nausea and vomiting in children. An evidence-based approach]
    M R Tramer
    Service d anesthésiologie, Hopitaux Universitaires de Geneve, Geneve, Switzerland
    Ann Fr Anesth Reanim 26:529-34. 2007
    ..The lack of relevant paediatric PONV data remains a major drawback and is highly unsatisfactory. Hopefully, future research will further improve the control of PONV not only in adults but also in children...
  6. ncbi request reprint [Postoperative nausea and vomiting]
    M R Tramer
    Service d anesthésiologie, Département APSI, Hopitaux Universitaires de Geneve, 1211 Geneve 14, Schweiz
    Anaesthesist 56:679-85. 2007
    ..Unless more reliable risk scores are developed, aggressive treatment of established PONV symptoms may be more useful and more cost-effective than prophylaxis for many patients...
  7. ncbi request reprint An evaluation of a single dose of magnesium to supplement analgesia after ambulatory surgery: randomized controlled trial
    Martin R Tramer
    Division of Anesthesiology, Department Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 104:1374-9, table of contents. 2007
    ..Previous studies have suggested that magnesium may be a useful adjuvant to postoperative analgesia...
  8. pmc Pharmacological prevention of serious anaphylactic reactions due to iodinated contrast media: systematic review
    Martin R Tramer
    Division of Anaesthesiology, Geneva University Hospitals, CH 1211 Geneva, Switzerland
    BMJ 333:675. 2006
    ..To review the efficacy of pharmacological prevention of serious reactions to iodinated contrast media...
  9. ncbi request reprint [The pharmacology of PONV control: prevention or treatment?]
    M R Tramer
    Division Anästhesie, Universitatskliniken, CH 1211 Genf 14, Schweiz
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:493-7. 2005
  10. ncbi request reprint [Meta-analysis. A meaningful tool for evidence-based (intensive) medicine]
    M R Tramer
    Division d Anesthésiologie, Departement Anesthesiologie, Pharmacologie et Soins Intensifs Chirurgicaux, Hopitaux Universitaires de Geneve, Switzerland
    Anaesthesist 52:S5-6. 2003
  11. ncbi request reprint Number needed to treat (or harm)
    Martin R Tramer
    Division of Anesthesiology, Department APSIC, Geneva University Hospitals, Geneva, Switzerland
    World J Surg 29:576-81. 2005
    ..Absolute risk reduction and number needed to treat should become standard summary estimates in randomized controlled trials...
  12. pmc It's not just about rubbing--topical capsaicin and topical salicylates may be useful as adjuvants to conventional pain treatment
    Martin R Tramer
    Division of Anaesthesiology, Geneva University Hospitals, CH 1211 Geneva 14, Switzerland
    BMJ 328:998. 2004
  13. ncbi request reprint Magnesium Bier's block for treatment of chronic limb pain: a randomised, double-blind, cross-over study
    Martin R Tramer
    Division of Anaesthesiology, Geneva University Hospitals, CH 1211 Geneva 14, Switzerland
    Pain 99:235-41. 2002
    ..The optimal dose of lignocaine to prevent magnesium-induced aching of the treated limb needs to be established. Bier's block with magnesium-lignocaine may provide a possible treatment alternative in these patients...
  14. ncbi request reprint Strategies for postoperative nausea and vomiting
    Martin R Tramer
    Division of Anaesthesiology, Department APSIC, Geneva University Hospitals, CH 1211 Geneva 14, Switzerland
    Best Pract Res Clin Anaesthesiol 18:693-701. 2004
    ..For patients who are identified as high-risk patients, all measurements should be simultaneously initiated (multimodal anti-emesis)...
  15. ncbi request reprint Efficacy and adverse effects of prophylactic antiemetics during patient-controlled analgesia therapy: a quantitative systematic review
    M R Tramer
    Department APSIC, Geneva University Hospital, Switzerland
    Anesth Analg 88:1354-61. 1999
    ..7 (95% confidence interval 1.8-5.2), and that to prevent vomiting was 3.1 (2.3-4.8). Compared with placebo, the incidence of minor adverse effects with droperidol was increased with doses >4 mg/d...
  16. ncbi request reprint Quantitative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use
    M R Tramer
    Division d Anesthésiologie, Departement APSIC, Hopitaux Universitaires, CH 1211, Geneva, Switzerland
    Pain 85:169-82. 2000
    ..On average 1 in 1200 patients taking NSAIDs for at least 2 months will die from gastroduodenal complications who would not have died had they not taken NSAIDs. This extrapolates to about 2000 deaths each year in the UK...
  17. pmc Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review
    M R Tramer
    Division d Anesthésiologie, Departement Anesthesiologie, Pharmacologie Clinique et Soins Intensif de Chirurgie, Hopitaux Universitaires, CH 1211 Geneve 14, Switzerland
    BMJ 323:16-21. 2001
    ..To quantify the antiemetic efficacy and adverse effects of cannabis used for sickness induced by chemotherapy...
  18. ncbi request reprint Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques
    M R Tramer
    Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospital, Switzerland
    Acta Anaesthesiol Scand 42:117-23. 1998
    ..Oculocardiac reflex (OCR) and postoperative vomiting are major complications of paediatric strabismus surgery...
  19. doi request reprint Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials
    N Meylan
    Division of Anaesthesiology, University Hospitals of Geneva, 24, Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Br J Anaesth 102:156-67. 2009
    ..Morphine-sparing is more pronounced after abdominal than after cardiac-thoracic surgery. Respiratory depression remains a major safety concern...
  20. doi request reprint Intravenous lidocaine has no impact on rocuronium-induced neuromuscular block. Randomised study
    C Czarnetzki
    Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland
    Acta Anaesthesiol Scand 56:474-81. 2012
    ..Intravenous lidocaine is increasingly used in surgical patients. As it has neuromuscular blocking effects, we tested the impact of an intravenous lidocaine infusion on the time course of a rocuronium-induced neuromuscular block...
  21. doi request reprint Time course of rocuronium-induced neuromuscular block after pre-treatment with magnesium sulphate: a randomised study
    C Czarnetzki
    Division of Anaesthesiology, University Hospitals of Geneva, CH 1211 Geneva 14, Switzerland
    Acta Anaesthesiol Scand 54:299-306. 2010
    ..A previously published study suggested that pre-treatment with magnesium sulphate (MgSO(4)) had no impact on the speed of onset of rocuronium-induced neuromuscular block. We set out to verify this assumption...
  22. ncbi request reprint Magnesium for the prevention and treatment of acute mountain sickness
    Lionel Dumont
    Neuroanaesthesia Unit, Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Clin Sci (Lond) 106:269-77. 2004
    ..05 (0.01-0.25)]. In conclusion, oral magnesium does not prevent AMS. In subjects with established AMS, intravenous magnesium reduces the severity of symptoms to some extent, but this effect is of no clinical importance...
  23. ncbi request reprint A lack of evidence of superiority of propofol versus midazolam for sedation in mechanically ventilated critically ill patients: a qualitative and quantitative systematic review
    B Walder
    Divisions of Surgical Intensive Care, Department APSIC, University Hospitals of Geneva, Switzerland
    Anesth Analg 92:975-83. 2001
    ..7]; number-needed-to-treat, 6) occurred more often with propofol. The duration of adequate sedation time is longer with propofol compared with midazolam. In postoperative patients with sedation <36 h, weaning is faster with propofol...
  24. pmc Efficacy and harm of pharmacological prevention of acute mountain sickness: quantitative systematic review
    L Dumont
    Division of Anaesthesiology, Department APSIC, University of Geneva Hospitals, CH 1211 Geneva 14, Switzerland
    BMJ 321:267-72. 2000
    ..To quantify efficacy and harm of pharmacological prevention of acute mountain sickness...
  25. ncbi request reprint Efficacy and safety of patient-controlled opioid analgesia for acute postoperative pain. A quantitative systematic review
    B Walder
    Division of Surgical Intensive Care, Department APSIC, Geneva University Hospitals, Geneva, Switzerland
    Acta Anaesthesiol Scand 45:795-804. 2001
    ..The usefulness of intravenous patient-controlled analgesia (PCA) with opioids for postoperative analgesia is not well defined...
  26. ncbi request reprint Size is everything--large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects
    R A Moore
    Pain Research, Nuffield Department of Anaesthetics, The Churchill, Oxford Radcliffe Hospital, UK
    Pain 78:209-16. 1998
    ..Credible estimates of clinical efficacy are only likely to come from large trials or from pooling multiple trials of conventional (small) size...
  27. ncbi request reprint The effect of cigarette smoking on the hypnotic efficacy of propofol
    C Lysakowski
    Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anaesthesia 61:826-31. 2006
    ..04. The hypnotic efficacy of propofol is reduced when used at low effect-site concentrations in smokers. This phenomenon may have some impact on the management of smokers undergoing sedation using target controlled infusion systems...
  28. ncbi request reprint Impact of the intubation model on the efficacy of rocuronium during rapid sequence intubation: systematic review of randomized trials
    C Lysakowski
    Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    Acta Anaesthesiol Scand 51:848-57. 2007
    ..Propofol-rocuronium is thought to be superior to thiopental-rocuronium for rapid sequence intubation (RSI). The role of the intubation model per se has never been investigated...
  29. ncbi request reprint Analgesia and sedation in critically ill patients
    Bernhard Walder
    Division of Anaesthesiology, Department APSIC, Geneva University Hospitals, Switzerland
    Swiss Med Wkly 134:333-46. 2004
    ..Implementation of guidelines for rational analgesia and sedation would help to reduce patients' length of stay in the intensive care unit...
  30. ncbi request reprint Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials
    Nadia Elia
    Division of Anesthesiology, University Hospitals of Geneva, Geneva
    Reg Anesth Pain Med 33:159-67. 2008
    ..The aim of this systematic review is to quantify beneficial and harmful effects of clonidine when used as an adjuvant to intrathecal local anesthetics for surgery...
  31. ncbi request reprint Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial
    Laszlo Vutskits
    Division of Anesthesiology, University Hospitals of Geneva, 24, Rue Micheli du Crest, CH 1211, Geneva 14, Switzerland
    Neurochem Res 33:1325-31. 2008
    ..These data suggest that in males undergoing elective minor surgery, BDNF plasma concentrations show a specific pattern that is influenced by the anesthetic technique and, possibly, by the duration of surgery...
  32. ncbi request reprint Primer: strengths and weaknesses of meta-analysis
    Axel Finckh
    Division of Rheumatology at University Hospitals of Geneva, Geneva, Switzerland
    Nat Clin Pract Rheumatol 4:146-52. 2008
    ..In this Review we examine the analytical strengths of, and the main problems encountered by, both systematic reviews and meta-analyses, focusing on how to best assess the validity of each for the practicing clinician...
  33. ncbi request reprint Do we need preemptive analgesia for the treatment of postoperative pain?
    Sina Grape
    Division of Anaesthesiology, Geneva University Hospitals, CH 12 11 Geneva, Switzerland
    Best Pract Res Clin Anaesthesiol 21:51-63. 2007
    ..e. a multimodal approach including the combination of strong opioids, non-opioid analgesics, and peripheral or neuraxial local anaesthetics that act at different sites of the pain pathways...
  34. ncbi request reprint Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA testing? A systematic review and meta-analysis
    Patrick Petignat
    Senology and Gynaecologic Oncology Unit, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Gynecol Oncol 105:530-5. 2007
    ..To compare the detection rate of genital human papillomavirus (HPV) infection in self- and physician-obtained samples...
  35. ncbi request reprint Respiratory physiotherapy to prevent pulmonary complications after abdominal surgery: a systematic review
    Patrick Pasquina
    Division of Intensive Care, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Chest 130:1887-99. 2006
    ..To examine the efficacy of respiratory physiotherapy for prevention of pulmonary complications after abdominal surgery...
  36. ncbi request reprint Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial
    Christoph Czarnetzki
    Division of Anesthesiology, University Hospitals of Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    JAMA 300:2621-30. 2008
    ..Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy...
  37. ncbi request reprint Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials
    Nadia Elia
    Division of Anesthesiology, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Anesthesiology 103:1296-304. 2005
    ..There is evidence that the combination of nonsteroidal antiinflammatory drugs with patient-controlled analgesia morphine offers some advantages over morphine alone...
  38. doi request reprint Osteoarthritis: Small studies overestimate the benefit of therapies for OA
    Axel Finckh
    Division of Rheumatology, University Hospitals of Geneva, Avenue Beau Séjour 26, CH 1211 Geneva 14, Switzerland A
    Nat Rev Rheumatol 6:617-8. 2010
    ..Does this mean meta-analyses should be restricted to trials with large sample sizes?..
  39. ncbi request reprint Spontaneous subarachnoid hemorrhage and serious cardiopulmonary dysfunction--a systematic review
    Lucian M Macrea
    Division of Anesthesiology, Department APSIC Anesthesiology, Pharmacology, and Surgical Intensive Care, Geneva University Hospitals, Rue Micheli du Crest 24, CH 1211, Geneva 14, Switzerland
    Resuscitation 65:139-48. 2005
    ..The association between the degree of neurological deficit and cardiopulmonary dysfunction in patients with spontaneous subarachnoid hemorrhage (SAH) is poorly understood...
  40. pmc Transcutaneous nicotine does not prevent postoperative nausea and vomiting: a randomized controlled trial
    Christoph Czarnetzki
    Division of Anaesthesiology Clinical Trial Unit, University Hospitals of Geneva, Geneva, Switzerland Department of Neurosciences Medical Faculty, University of Geneva, Geneva, Switzerland
    Br J Clin Pharmacol 71:383-90. 2011
    ..There is empirical evidence that smokers are less likely to suffer from postoperative nausea and vomiting (PONV). We sought to investigate whether transcutaneus nicotine prevents PONV...
  41. ncbi request reprint Is low-dose haloperidol a useful antiemetic?: A meta-analysis of published and unpublished randomized trials
    Michael Buttner
    Division of Anesthesiology, Geneva University Hospitals, Switzerland
    Anesthesiology 101:1454-63. 2004
    ..4). There were no reports on cardiac toxicity. Postoperatively and in gastroenterology, haloperidol is antiemetic, with minimal toxicity. For other clinical settings and for children, valid data are unavailable...
  42. ncbi request reprint A needle-free jet-injection system with lidocaine for peripheral intravenous cannula insertion: a randomized controlled trial with cost-effectiveness analysis
    Christopher Lysakowski
    Division of Anesthesiology, Department of APSIC Anesthesiology, Pharmacology, and Surgical Intensive Care, Geneva University Hospitals, Switzerland
    Anesth Analg 96:215-9, table of contents. 2003
    ..Lidocaine-Jet is analgesic; there is dose-responsiveness. However, Jet treatment is not painless, and costs incurred to achieve one success compared with doing nothing are not negligible...
  43. ncbi request reprint Seizure-like phenomena and propofol: a systematic review
    Bernhard Walder
    Department APSIC, Functional Neurology and Neurosurgery Program of the University of Geneva, Switzerland
    Neurology 58:1327-32. 2002
    ..To confirm this hypothesis, to estimate the prevalence of propofol-related SLP, and to identify patients at risk, data of higher quality are needed...
  44. ncbi request reprint Effect of magnesium, high altitude and acute mountain sickness on blood flow velocity in the middle cerebral artery
    Christopher Lysakowski
    Neuroanaesthesia Unit, Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Clin Sci (Lond) 106:279-85. 2004
    ..s(-1) before compared with 67 +/- 16 cm.s(-1) after rescue medication; P=0.79). MCAv was increased in subjects who received magnesium, but was not affected by exposure to high altitude or by severe AMS...
  45. ncbi request reprint The antiemetic efficacy of droperidol added to morphine patient-controlled analgesia: a randomized, controlled, multicenter dose-finding study
    Xavier Culebras
    Division d Anesthésie, Departement APSIC, Hopitaux Universitaires de Geneve, Geneve, Switzerland
    Anesth Analg 97:816-21. 2003
    ..There was no difference in patient satisfaction. The optimal antiemetic dose of droperidol is 15-50 micro g/mg of morphine. Larger doses may have more antivomiting efficacy but are likely to be unacceptably sedating...
  46. pmc Prophylactic respiratory physiotherapy after cardiac surgery: systematic review
    Patrick Pasquina
    Division of Surgical Intensive Care, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Switzerland
    BMJ 327:1379. 2003
    ..To assess whether respiratory physiotherapy prevents pulmonary complications after cardiac surgery...
  47. ncbi request reprint Ketamine and postoperative pain--a quantitative systematic review of randomised trials
    Nadia Elia
    EBCAP Institute Evidence Based Critical care, Anaesthesia and Pain treatment, Division of Anaesthesiology, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Pain 113:61-70. 2005
    ..49 (95%CI 0.18-12.6), NNH 286. Despite many published randomised trials, the role of ketamine, as a component of perioperative analgesia, remains unclear...
  48. ncbi request reprint Pharmacologic myocardial protection in patients undergoing noncardiac surgery: a quantitative systematic review
    Robert D Stevens
    Division of Anesthesiology, Department APSIC, Geneva University Hospitals, Switzerland
    Anesth Analg 97:623-33. 2003
    ..The most common adverse effect was bradycardia, which occurred in 24.5% of patients receiving a beta adrenergic blocker versus 9.1% of controls (OR 3.76 [95% CI, 2.45-5.77], NNH 6)...
  49. doi request reprint Ventilation strategies in obese patients undergoing surgery: a quantitative systematic review and meta-analysis
    M Aldenkortt
    Division of Anaesthesia, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Br J Anaesth 109:493-502. 2012
    ..The ideal ventilation strategy is expected to optimize gas exchange and pulmonary mechanics and to reduce the risk of respiratory complications...
  50. ncbi request reprint Transcranial Doppler versus angiography in patients with vasospasm due to a ruptured cerebral aneurysm: A systematic review
    C Lysakowski
    Divisions of Anesthesiology, Neuroanesthesia Unit, Geneva University Hospitals, Geneva, Switzerland
    Stroke 32:2292-8. 2001
    ..Our aim was to evaluate both the accuracy of TCD compared with angiography and its usefulness as a screening method in this setting...
  51. ncbi request reprint [Evidence-based medicine and the systematic review in perioperative medicine]
    B Walder
    Division des Soins Intensifs Chirurgicaux, Departement Anesthesiologie, Pharmacologie et Soins Intensifs Chirurgicaux, Hopitaux Universitaires, 1211 Geneve 14, Schweiz
    Anaesthesist 50:689-94. 2001
    ..In the specific settings of perioperative medicine the number of systematic reviews has become so important that recommendations for evidenced-based strategies of prevention and therapy can be formulated...
  52. doi request reprint Susceptibility to fraud in systematic reviews: lessons from the Reuben case
    Emmanuel Marret
    Division of Anesthesiology, Department of Anesthesiology, Critical Care and Clinical Pharmacology, Geneva University Hospitals, Geneva, Switzerland
    Anesthesiology 111:1279-89. 2009
    ..Dr. Scott Reuben allegedly fabricated data. The authors of the current article examined the impact of Reuben reports on conclusions of systematic reviews...
  53. doi request reprint Nefopam for the prevention of postoperative pain: quantitative systematic review
    M S Evans
    Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    Br J Anaesth 101:610-7. 2008
    ..However, dose responsiveness and adverse effect profile remain unclear, and the role of nefopam as part of multimodal analgesia needs to be established. Data in children are lacking...
  54. doi request reprint Bispectral and spectral entropy indices at propofol-induced loss of consciousness in young and elderly patients
    C Lysakowski
    Division of Anaesthesiology, University Hospitals of Geneva, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    Br J Anaesth 103:387-93. 2009
    ..Since the EEG is changing with increasing age, we investigated the impact of advanced age on BIS, SE, and RE indices during induction...
  55. ncbi request reprint Different patterns of duplicate publication: an analysis of articles used in systematic reviews
    Erik von Elm
    Division of Anesthesiology, Department of Anesthesiology, Pharmacology, and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    JAMA 291:974-80. 2004
    ..Duplicate publication is publication of an article that overlaps substantially with an article published elsewhere. Patterns of duplication are not well understood...
  56. ncbi request reprint Does meta-analysis increase our knowledge in the management of postoperative nausea and vomiting?
    Martin R Tramer
    Division of Anesthesiology, Geneva University Hospitals, CH 1211 Geneva 14 Switzerland
    Int Anesthesiol Clin 41:33-9. 2003
  57. ncbi request reprint Prevention of bloodstream infections with central venous catheters treated with anti-infective agents depends on catheter type and insertion time: evidence from a meta-analysis
    Bernhard Walder
    Division of Surgical Intensive Care, University of Geneva Hospitals, Geneva, Switzerland
    Infect Control Hosp Epidemiol 23:748-56. 2002
    ..To test the evidence that the risk of infection related to central venous catheters (CVCs) is decreased by anti-infective coating or cuffing...
  58. ncbi request reprint Colonization and bloodstream infection with single- versus multi-lumen central venous catheters: a quantitative systematic review
    Mathias Zürcher
    Division of Surgical Intensive Care and the Center for Evidence Based Critical Care, Anesthesia and Pain Treatment, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 99:177-82. 2004
    ..The risk of catheter colonization is not decreased. Although these conclusions are based on limited data, single-lumen catheters should be used whenever feasible...