Research Topics
| J-M TiercySummaryAffiliation: University of Geneva Country: Switzerland Publications
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Detail Information
Publications
Sequence of a new DR12 allele with two silent mutations that affect PCR-SSP typingR Zanone
National Reference Laboratory for Histocompatibility, Transplantation Immunology Unit, University Hospital, Geneva, Switzerland
Tissue Antigens 59:165-7. 2002..The complete HLA type of the donor is A24, A68; B55, B61; Cw*01, Cw*0304; DRB1*12012, DRB1*1402; DRB3*0101, DRB3*0202; DQB1*0301. HLA-DRB1*12012 is a rare allele as it occurs in < 0.2% of DR12 donors...- Impact of high-resolution matching in allogeneic unrelated donor stem cell transplantation in SwitzerlandY Chalandon
Hematology Service, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Bone Marrow Transplant 37:909-16. 2006..Single mismatches at HLA-DQ/-DRB3 were well tolerated, mismatches at HLA-C had intermediate results and mismatches at HLA-A/-B/-DRB1/multiple loci resulted in poor survival... - The probability of identifying a 10/10 HLA allele-matched unrelated donor is highly predictableJ M Tiercy
Department of Internal Medicine, National Reference Laboratory for Histocompatibility, University Hospital, Geneva, Switzerland
Bone Marrow Transplant 40:515-22. 2007..Probability prediction is therefore feasible in the search process for unrelated donors and can guide the therapeutic strategy... - A new DR7-DQ8 haplotype resulting from a recombination between the DQA1 and DQB1 loci in a leukemic patient of Caucasoid originJean Marie Tiercy
Transplantation Immunology Unit, National Reference Laboratory for Histocompatibility, University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 4, Switzerland
Immunogenetics 56:301-3. 2004..Out of three potential donors, only one HLA-A/-B/-C/DRB1-compatible but DQB1-mismatched donor could be identified... - Guidelines for nomenclature usage in HLA reports: ambiguities and conversion to serotypesJ-M Tiercy
Transplantation Immunology Unit, University Hospital, Geneva, Switzerland
Eur J Immunogenet 29:273-4. 2002 - Selection of unrelated bone marrow donors by serology, molecular typing and cellular assaysJean Marie Tiercy
National Reference Laboratory for Histocompatibility, University Hospital, Geneva, Switzerland
Transpl Immunol 10:215-21. 2002.... - Quality control for registry HLA dataJ M Tiercy
National Reference Laboratory for Histocompatibility, University Hospital, Geneva, Switzerland
Tissue Antigens 69:13-4. 2007.... - Analysis of 250 HLA-B44 genotypes in European Caucasoids: high diversity and preferential ABCDRB1 associations in B*4402, B*4403, and B*4405 haplotypesJ M Tiercy
National Reference Laboratory for Histocompatibility, Transplantation Immunology Unit, Division of Immunology and Allergology, University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 4, Switzerland
Tissue Antigens 65:429-36. 2005..HLA-C incompatibility rate was 22.2% for the patients with > or =1 B44 allele-matched donor(s). This dataset can therefore be used as a predictive tool for B44- and C-disparities in unrelated stem cell transplantation... - Quality control of a national bone marrow donor registry: results of a pilot study and proposal for a standardized approachJ M Tiercy
Transplantation Immunology Unit LNRH, University Hospital, Geneva, Switzerland
Bone Marrow Transplant 32:623-7. 2003..These data show that standardized quality control for donor availability and HLA typing is feasible, and we propose that this model could be applied to the registries participating in bone marrow donor worldwide... 
DNA typing by microbead arrays and PCR-SSP: apparent false-negative or -positive hybridization or amplification signals disclose new HLA-B and -DRB1 allelesM Rahal
Transplantation Immunology Unit LNRH, University Hospital Geneva, Geneva, Switzerland
Tissue Antigens 71:238-41. 2008..To avoid allele misassignments, a comprehensive evaluation of acquired data as documented in a quality assurance system is therefore required to confirm unambiguous typing interpretation...- Isolated HLA-C mismatches in unrelated donor transplantation for CMLJ M Tiercy
Division of Immunology and Allergology, University Hospital, Geneva, Switzerland
Bone Marrow Transplant 34:249-55. 2004..9; CI, 1-3.9, P=0.06, TRM: RR, 2.1; CI, 1-4.5, P=0.07). In spite of their lower expression, HLA-C antigens still represent relevant transplantation barriers that should be considered when searching for an unrelated donor... - HLA-C molecular characterization of a Lebanese population and genetic structure of 39 populations from Europe to India-PakistanS Buhler
Laboratory of Anthropology, Genetics and Peopling History (AGP, Department of Anthropology and Ecology, University of Geneva, Geneva, Switzerland
Tissue Antigens 68:44-57. 2006..Overall, the results show that the HLA-C genetic patterns of these three geographic regions, i.e., the Middle East, Europe, and India-Pakistan, have been shaped by very different genetic histories... - Additional diversity within the B70 serotype: identification of B*1580 in a Caucasoid blood donorB Kervaire
National Reference Laboratory for Histocompatibility, Transplantation Immunology Unit, Division of Immunology and Allergology, University Hospital, Geneva, Switzerland
Tissue Antigens 63:270-2. 2004..Based on sequence similarity and linkage with Cw*0704, the rare alleles B*1509, B*1529, B*1564, and B*1580 are possibly derived from the B*1518 haplotype... - PCR-SSOP molecular typing of HLA-C alleles in an Iranian populationS Buhler
Laboratory of Genetics and Biometry, University of Geneva, Switzerland
Tissue Antigens 59:525-30. 2002..A total of 30 HLA-C-DRB1 haplotypes were found in the Iranians, with the highest frequencies of 6.6% and 6.04 % being for Cw*0602-DRB1*0701 and Cw*1202-DRB1*1502, respectively...