L Terracciano

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Langerhans cell histiocytosis of the stomach with atypical morphological features
    L Terracciano
    Institute of Pathology, University Hospital of Basel, Switzerland
    Pathol Int 49:553-6. 1999
  2. ncbi Cytogenetic alterations in liver cell tumors as detected by comparative genomic hybridization
    L Terracciano
    Department of Pathology, Liver and Gastrointestinal Pathology Section, University of Basel, Switzerland
    Pathologica 95:71-82. 2003
  3. ncbi HER2 gene status in primary breast cancers and matched distant metastases
    Coya Tapia
    University Department of Pathology of Basel and Baselland, Institute for Pathology, Schonbeinstrasse 40, Basel, 4003, Switzerland
    Breast Cancer Res 9:R31. 2007
  4. ncbi Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours
    Dolores Di Vizio
    Department of Functional and Biomorphological Science, University Federico II, Naples, Italy
    BMC Cancer 8:134. 2008
  5. ncbi Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer
    Manuela Eppenberger
    Institute of Pathology, University Hospital of Basel, Basel, Switzerland
    BMC Cancer 10:93. 2010
  6. ncbi Fibrolamellar hepatocellular carcinoma occurring 5 years after hepatocellular adenoma in a 14-year-old girl: a case report with comparative genomic hybridization analysis
    Luigi Maria Terracciano
    Institute of Pathology, University of Basel, Basel, Switzerland
    Arch Pathol Lab Med 128:222-6. 2004
  7. ncbi Hepatoid adenocarcinoma with liver metastasis mimicking hepatocellular carcinoma: an immunohistochemical and molecular study of eight cases
    Luigi M Terracciano
    Institute of Pathology, Schonbeinstrasse 40, University Hospital Basel, 4003 Basel, Switzerland
    Am J Surg Pathol 27:1302-12. 2003
  8. ncbi Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer
    A Lugli
    Institute of Pathology, University of Basel, Basel, Switzerland
    Br J Cancer 103:382-90. 2010
  9. ncbi Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients
    I Zlobec
    Institute for Pathology, University Hospital of Basel, 4031 Basel, Switzerland
    Br J Cancer 102:151-61. 2010
  10. ncbi Two-marker protein profile predicts poor prognosis in patients with early rectal cancer
    I Zlobec
    Institute of Pathology, University Hospital of Basel, Basel, Switzerland
    Br J Cancer 99:1712-7. 2008

Detail Information

Publications37

  1. ncbi Langerhans cell histiocytosis of the stomach with atypical morphological features
    L Terracciano
    Institute of Pathology, University Hospital of Basel, Switzerland
    Pathol Int 49:553-6. 1999
    ..Typical Birbeck granules could be identified in almost all cells. Cell nuclei analyzed by flow cytometry showed an aneuploid peak, a feature typically associated with malignant disease...
  2. ncbi Cytogenetic alterations in liver cell tumors as detected by comparative genomic hybridization
    L Terracciano
    Department of Pathology, Liver and Gastrointestinal Pathology Section, University of Basel, Switzerland
    Pathologica 95:71-82. 2003
    ..HB. Alterations that were typical for hepatoblastoma included Xp+ and Xq+, which were found both in the mesenchymal and in the epithelial parts of HBs. Other frequent changes in these tumor types included 1p-, 9p- and 2q+...
  3. ncbi HER2 gene status in primary breast cancers and matched distant metastases
    Coya Tapia
    University Department of Pathology of Basel and Baselland, Institute for Pathology, Schonbeinstrasse 40, Basel, 4003, Switzerland
    Breast Cancer Res 9:R31. 2007
    ..Here, we compared HER2 status on cytological specimens of distant metastases with the result from the primary carcinomas, and explored the prevalence of and the reasons for discrepant results...
  4. ncbi Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours
    Dolores Di Vizio
    Department of Functional and Biomorphological Science, University Federico II, Naples, Italy
    BMC Cancer 8:134. 2008
    ..The aim of our study was to investigate the role of morphologic parameters and expression of cells cycle regulators as prognosticators in GIST...
  5. ncbi Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer
    Manuela Eppenberger
    Institute of Pathology, University Hospital of Basel, Basel, Switzerland
    BMC Cancer 10:93. 2010
    ..The aim of this study was to elucidate the role of the VEGF ligand/receptor ratios on tumour progression and metastasis in patients with mismatch repair-proficient colorectal cancer...
  6. ncbi Fibrolamellar hepatocellular carcinoma occurring 5 years after hepatocellular adenoma in a 14-year-old girl: a case report with comparative genomic hybridization analysis
    Luigi Maria Terracciano
    Institute of Pathology, University of Basel, Basel, Switzerland
    Arch Pathol Lab Med 128:222-6. 2004
    ..To our knowledge, this is the first report of an association between hepatocellular adenoma and fibrolamellar carcinoma...
  7. ncbi Hepatoid adenocarcinoma with liver metastasis mimicking hepatocellular carcinoma: an immunohistochemical and molecular study of eight cases
    Luigi M Terracciano
    Institute of Pathology, Schonbeinstrasse 40, University Hospital Basel, 4003 Basel, Switzerland
    Am J Surg Pathol 27:1302-12. 2003
    ..Comparative genomic hybridization study of three HAC supports their hepatoid differentiation as aberrations found in HAC are common in HCC (4q-, 8p-), and hepatoblastoma (Xq+), respectively...
  8. ncbi Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer
    A Lugli
    Institute of Pathology, University of Basel, Basel, Switzerland
    Br J Cancer 103:382-90. 2010
    ..The aim of this study was to elucidate the prognostic impact of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and aldehyde dehydrogenase-1 (ALDH1) in colorectal cancer...
  9. ncbi Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients
    I Zlobec
    Institute for Pathology, University Hospital of Basel, 4031 Basel, Switzerland
    Br J Cancer 102:151-61. 2010
    ....
  10. ncbi Two-marker protein profile predicts poor prognosis in patients with early rectal cancer
    I Zlobec
    Institute of Pathology, University Hospital of Basel, Basel, Switzerland
    Br J Cancer 99:1712-7. 2008
    ..009) only. RHAMM and CD8(+) TILs may assist in identifying early stage rectal cancer patients facing a particularly poor prognosis and who may derive a benefit from preoperative therapy...
  11. ncbi Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer
    I Zlobec
    Institute of Pathology, University Hospital of Basel, Schonbeinstrasse 40, Basel, CH 4031, Switzerland
    Gut 57:1413-9. 2008
    ....
  12. ncbi Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers
    S Savic
    Institute for Pathology, University Hospital Basel, Basel, Switzerland
    Br J Cancer 98:154-60. 2008
    ..New criteria for a positive EGFR FISH status to predict response to therapy with EGFR-TKI need to be defined for cytological specimens...
  13. ncbi Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers
    P Went
    Institute of Pathology, University Hospital Basel, Schonbeinstrasse 40, 4003 Basel, Switzerland
    Br J Cancer 94:128-35. 2006
    ....
  14. ncbi [44 year old gardener with lower back pain, myalgia and fever]
    D Bareiss
    Abteilung fur Innere Medizin, Universitatsspital Basel, Basel
    Praxis (Bern 1994) 99:127-32. 2010
    ..Eating shellfish at the East Sea 4 weeks prior to admission or handling natural animal dung during her work as a gardener. One year after the event the patient once again is healthy and well...
  15. ncbi Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes
    C Feder-Mengus
    ICFS, Departments of Surgery and Research, Basel University Hospital, Hebelstrasse 20, CH 4031 Basel, Switzerland
    Br J Cancer 96:1072-82. 2007
    ..These data suggest that melanoma cells growing in 3D, even in the absence of immune selection, feature characteristics capable of dramatically inhibiting TAA recognition by specific CTL...
  16. ncbi [Neurogenic appendicopathy: a frequent, almost unknown disease picture. Evaluation of 816 appendices and review of the literature]
    U Guller
    Allgemeinchirurgische Klinik, Departement Chirurgie der Universität Basel, Kantonsspital Basel, Schweiz
    Chirurg 72:684-9. 2001
    ..We evaluated the incidence of NA in macroscopically normal specimens from patients presenting the symptoms of acute appendicitis and in incidental appendectomies...
  17. ncbi [Differentiated papillary kidney tumors. Differentiation between metanephric adenoma and papillary adenoma]
    A Lugli
    Institut für Pathologie der Universität Basel, Basel
    Pathologe 23:303-7. 2002
    ..The knowledge of the immunohistochemical constellation is important, because metanephric adenoma can be very large and often have some necrosis...
  18. ncbi CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer
    A Lugli
    Institute of Pathology, University of Basel, Basel, Switzerland
    Br J Cancer 101:1382-92. 2009
    ....
  19. ncbi FLT3 ligand gene expression and protein production in human colorectal cancer cell lines and clinical tumor specimens
    G C Spagnoli
    Department of Surgery, Division of Research, University of Basel, Basel, Switzerland
    Int J Cancer 86:238-43. 2000
    ..FL content in preoperative sera from colorectal cancer patients (n = 13) did not exceed the levels detected in healthy donors (</= 100 pg/ml)...
  20. ncbi Combined copy status of 18q21 genes in colorectal cancer shows frequent retention of SMAD7
    J L Boulay
    Department of Research, University Hospital of Basel, Basel, Switzerland
    Genes Chromosomes Cancer 31:240-7. 2001
    ....
  21. ncbi Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6
    S Volarevic
    Friedrich Miescher Institute, Maulbeerstrasse 66, CH 4058, Basel, Switzerland
    Science 288:2045-7. 2000
    ..These results imply that abrogation of 40S ribosome biogenesis may induce a checkpoint control that prevents cell cycle progression...
  22. ncbi Hepatitis with fibrin-ring granulomas
    B Khanlari
    Dept Internal Medicine, University Hospital, Basel, Switzerland
    Infection 36:381-3. 2008
    ..The history revealed a travel to Malta 2 years earlier. Despite adequate treatment with liposomal amphotericin B the patient deteriorated and finally died in septic shock...
  23. ncbi Rare expression of KIT (CD117) in lymphomas: a tissue microarray study of 1166 cases
    A Zimpfer
    Institute of Pathology, University of Basel, Basel, Switzerland
    Histopathology 45:398-404. 2004
    ..In the few positive cases, the aberrant expression is not caused by a mutation in the 'hot-spots' of the kit gene, indicating that treatment of these tumours with Imatinib may be ineffective...
  24. ncbi A simple and reproducible scoring system for EGFR in colorectal cancer: application to prognosis and prediction of response to preoperative brachytherapy
    I Zlobec
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Br J Cancer 96:793-800. 2007
    ..001). Epidermal growth factor receptor is a predictive marker of response to preoperative radiotherapy and an independent adverse prognostic factor CRC...
  25. ncbi Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status
    A Lugli
    Department of Pathology, McGill University, Duff Medical Building, Montreal, Quebec, Canada
    J Clin Pathol 60:534-9. 2007
    ..Objective: To determine the prognostic significance of MUC1 and MUC2 in CRC with different MMR statuses...
  26. ncbi Prostate-specific membrane antigen (PSMA) protein expression in normal and neoplastic tissues and its sensitivity and specificity in prostate adenocarcinoma: an immunohistochemical study using mutiple tumour tissue microarray technique
    P Mhawech-Fauceglia
    Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Histopathology 50:472-83. 2007
    ..To determine prostate-specific membrane antigen (PSMA) expression in normal tissues and in 3161 benign and malignant tumours and subsequently to define its sensitivity and specificity in prostatic adenocarcinoma (PaC)...
  27. ncbi Role of APAF-1, E-cadherin and peritumoral lymphocytic infiltration in tumour budding in colorectal cancer
    I Zlobec
    Department of Pathology, McGill University, Montreal, Canada
    J Pathol 212:260-8. 2007
    ..Loss of E-cadherin and APAF-1 within the main body of CRCs are independent predictors of tumour budding. The prognostic benefit of lymphocytic infiltration may be explained by the immune destruction of budding cells...
  28. ncbi Are the Mallory bodies and intracellular hyaline bodies in neoplastic and non-neoplastic hepatocytes related?
    H Denk
    Department of Pathology, Medical University of Graz, Graz, Austria
    J Pathol 208:653-61. 2006
    ..If p62 is induced alone, or at least prevails, IHBs may arise by aggregation. However, if abnormal keratins are present in addition to p62, p62 associates and co-aggregates with keratins, finally leading to classical MBs...
  29. ncbi Expression of MAGE tumour-associated antigens is inversely correlated with tumour differentiation in invasive ductal breast cancers: an immunohistochemical study
    R Kavalar
    Maribor General Hospital, Slovenia
    Virchows Arch 439:127-31. 2001
    ..These data support the concept of specific immunotherapy in highly aggressive forms of breast neoplasms. Furthermore, they suggest that MAGE immunoreactivity could represent a tumour marker of potential prognostic relevance...
  30. ncbi Human aldehyde oxidase 1 interacts with ATP-binding cassette transporter-1 and modulates its activity in hepatocytes
    A Sigruener
    Institute of Clinical Chemistry and Laboratory Medicine, Regensburg University Medical Center, Regensburg, Germany
    Horm Metab Res 39:781-9. 2007
    ....
  31. ncbi Prognostic significance of the wnt signalling pathway molecules APC, beta-catenin and E-cadherin in colorectal cancer: a tissue microarray-based analysis
    A Lugli
    Department of Pathology, McGill University, Montreal, Canada
    Histopathology 50:453-64. 2007
    ....
  32. ncbi Hepatitis C virus carriers with persistently normal ALT levels: biological peculiarities and update of the natural history of liver disease at 10 years
    M Persico
    Internal Medicine and Hepatology Unit, Second University of Naples, Naples, Italy
    J Viral Hepat 13:290-6. 2006
    ..This study confirms that progression to cirrhosis is slow or absent in PNAL patients after 10 years of follow-up. Accordingly, the hepatic proliferative activity index is low and seems to be stable over time...
  33. ncbi [Bioptic diagnosis of chronic hepatitis. Results of an evidence-based consensus conference of the German Society of Pathology, of the German Society for Digestive and Metabolic Diseases and of Compensated Hepatitis (HepNet)]
    P Schirmacher
    Pathologisches Institut,
    Pathologe 25:337-48. 2004
  34. ncbi [Mixed epithelial and stromal tumor of the kidney]
    H Moch
    Institut für Klinische Pathologie Departement Pathologie, Universitatsspital Zurich
    Pathologe 25:356-61. 2004
    ....
  35. ncbi Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer
    C Mamot
    Divisin of Oncology, University Hospital Bassel, Switzerland
    Br J Cancer 88:420-3. 2003
    ..These results indicate that whereas Smad4 point mutations are prevalent in pancreatic carcinoma, they are infrequent in early stages (I-III) of colorectal cancer...
  36. ncbi SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer
    J L Boulay
    Department of Research, University Hospital, CH 4031 Basel, Switzerland
    Br J Cancer 87:630-4. 2002
    ..This data also indicate that integrity of this component of the transforming growth factor-beta/bone morphogenetic protein signalling pathway may be a critical factor for benefit of chemotherapy in patients with colorectal cancer...
  37. ncbi Intracystic papillary carcinoma of the male breast. A case report (histochemical, immunohistochemical and ultrastructural study)
    G De Rosa
    Institute of Pathology, II Faculty of Medicine and Surgery, University of Naples Federico II, Italy
    Tumori 78:37-42. 1992
    ....