Shin Takeda

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint DNA methylation and epigenetic inheritance during plant gametogenesis
    Shin Takeda
    Laboratory of Plant Genetics, University of Geneva, Science III, Switzerland
    Chromosoma 115:27-35. 2006
  2. pmc BRU1, a novel link between responses to DNA damage and epigenetic gene silencing in Arabidopsis
    Shin Takeda
    Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland
    Genes Dev 18:782-93. 2004
  3. ncbi request reprint Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinoma
    Toshiaki Mori
    Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Liver Int 25:380-8. 2005
  4. ncbi request reprint Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer
    Mitsuru Sakai
    Department of Surgery II, Nagoya University School of Medicine, Showa Ku, Nagoya 466 8560, Japan
    Cancer Sci 95:588-91. 2004
  5. ncbi request reprint Transcriptional activation mediated by binding of a plant GATA-type zinc finger protein AGP1 to the AG-motif (AGATCCAA) of the wound-inducible Myb gene NtMyb2
    Kazuhiko Sugimoto
    Department of Molecular Genetics, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8602, Japan
    Plant J 36:550-64. 2003
  6. ncbi request reprint Chromatin assembly factor 1 ensures the stable maintenance of silent chromatin states in Arabidopsis
    Tatsuya Ono
    Department of Integrated Genetics, National Institute of Genetics, Mishima 411 8540, Japan
    Genes Cells 11:153-62. 2006
  7. ncbi request reprint Aberrant methylation of the CHFR gene in advanced hepatocellular carcinoma
    Mitsuru Sakai
    Department of Surgery II, Graduate School of Medicine, Nagoya University, Japan
    Hepatogastroenterology 52:1854-7. 2005
  8. ncbi request reprint Overexpression of pituitary tumor transforming gene 1 in HCC is associated with angiogenesis and poor prognosis
    Tsutomu Fujii
    Department of Surgery II, Graduate School and Faculty of Medicine, Nagoya University, Nagoya, Japan
    Hepatology 43:1267-75. 2006
  9. ncbi request reprint Frequent promoter methylation of M-cadherin in hepatocellular carcinoma is associated with poor prognosis
    Suguru Yamada
    Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Anticancer Res 27:2269-74. 2007
  10. ncbi request reprint [Genetic detection and clinical applications in patients with hepatocellular carcinoma]
    Shin Takeda
    Department of Gastroenterological Surgery Surgery II, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 103:472-5. 2002

Collaborators

Detail Information

Publications16

  1. ncbi request reprint DNA methylation and epigenetic inheritance during plant gametogenesis
    Shin Takeda
    Laboratory of Plant Genetics, University of Geneva, Science III, Switzerland
    Chromosoma 115:27-35. 2006
    ..DME opposes transcriptional silencing associated with imprinting activities of the MEA/FIE polycomb group complex...
  2. pmc BRU1, a novel link between responses to DNA damage and epigenetic gene silencing in Arabidopsis
    Shin Takeda
    Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland
    Genes Dev 18:782-93. 2004
    ....
  3. ncbi request reprint Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinoma
    Toshiaki Mori
    Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Liver Int 25:380-8. 2005
    ..RUNX3 locus 1p36 is commonly deleted in a variety of human cancers, including HCC. Therefore, we examined genetic and epigenetic alterations of RUNX3 in human HCC...
  4. ncbi request reprint Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer
    Mitsuru Sakai
    Department of Surgery II, Nagoya University School of Medicine, Showa Ku, Nagoya 466 8560, Japan
    Cancer Sci 95:588-91. 2004
    ..Our results suggest that the aberrant methylation of CDH13 occurs frequently in pancreatic cancer, even at a relatively early stage...
  5. ncbi request reprint Transcriptional activation mediated by binding of a plant GATA-type zinc finger protein AGP1 to the AG-motif (AGATCCAA) of the wound-inducible Myb gene NtMyb2
    Kazuhiko Sugimoto
    Department of Molecular Genetics, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8602, Japan
    Plant J 36:550-64. 2003
    ..We also found that the AGP1 binding activity is highly enhanced by adenine methylation of the AG-motif by bacterial dam methylase...
  6. ncbi request reprint Chromatin assembly factor 1 ensures the stable maintenance of silent chromatin states in Arabidopsis
    Tatsuya Ono
    Department of Integrated Genetics, National Institute of Genetics, Mishima 411 8540, Japan
    Genes Cells 11:153-62. 2006
    ..Furthermore, TGS of the silent beta-glucuronidase (GUS) transgene was also de-repressed randomly in fas. We conclude that CAF-1 ensures the stable inheritance of epigenetic states through growth and development in Arabidopsis...
  7. ncbi request reprint Aberrant methylation of the CHFR gene in advanced hepatocellular carcinoma
    Mitsuru Sakai
    Department of Surgery II, Graduate School of Medicine, Nagoya University, Japan
    Hepatogastroenterology 52:1854-7. 2005
    ..We examined the methylation status of the CHFR gene in primary hepatocellular carcinomas (HCCs) and evaluated the correlation between the methylation status and the malignancy of HCC...
  8. ncbi request reprint Overexpression of pituitary tumor transforming gene 1 in HCC is associated with angiogenesis and poor prognosis
    Tsutomu Fujii
    Department of Surgery II, Graduate School and Faculty of Medicine, Nagoya University, Nagoya, Japan
    Hepatology 43:1267-75. 2006
    ..PTTG1 is overexpressed in HCC and our results suggest that PTTG1 mRNA expression has prognostic significance for the survival of postoperative patients with HCC...
  9. ncbi request reprint Frequent promoter methylation of M-cadherin in hepatocellular carcinoma is associated with poor prognosis
    Suguru Yamada
    Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Anticancer Res 27:2269-74. 2007
    ..Many cadherins (CDH) are associated with various types of cancer and their genetic and epigenetic alterations might be involved in carcinogenesis...
  10. ncbi request reprint [Genetic detection and clinical applications in patients with hepatocellular carcinoma]
    Shin Takeda
    Department of Gastroenterological Surgery Surgery II, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 103:472-5. 2002
    ..In future, HCC-specific genes and genes sensitive to radiation and chemotherapy are expected to have wide-spread clinical applications...
  11. ncbi request reprint Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor
    Tsutomu Fujii
    Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsuruma cho, Showa Ku, Nagoya 466 8550, Japan
    J Hepatol 41:104-11. 2004
    ..In the current study, we aimed to evaluate focal adhesion kinase (FAK), a non-receptor tyrosine kinase, expression in hepatocellular carcinoma (HCC), and to explore the prognostic significance of FAK...
  12. pmc An overview of gibberellin metabolism enzyme genes and their related mutants in rice
    Tomoaki Sakamoto
    Field Production Science Center, University of Tokyo, Nishi Tokyo, Tokyo 188 0002, Japan
    Plant Physiol 134:1642-53. 2004
    ....
  13. ncbi request reprint Biochemical analysis of long terminal repeat retrotransposons
    Andreas Bachmair
    Max Planck Institute for Plant Breeding Research, Cologne, Germany
    Methods Mol Biol 260:73-82. 2004
    ..References include some older key publications that may not be easily accessible via electronic databases. Methods for enrichment of viruslike particles from plant material and from yeast are described...
  14. ncbi request reprint Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis
    Osamu Okochi
    Second Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan
    Clin Cancer Res 9:5295-8. 2003
    ..Recently, it was demonstrated that SOCS-1 gene was silenced frequently by methylation of CpG island in human hepatocellular carcinoma (HCC). We examined the methylation-mediated silencing of SOCS-1 in tumors of HCC patients...
  15. pmc Target site specificity of the Tos17 retrotransposon shows a preference for insertion within genes and against insertion in retrotransposon-rich regions of the genome
    Akio Miyao
    Molecular Genetics Department, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8602, Japan
    Plant Cell 15:1771-80. 2003
    ..The nucleotide sequence data were uploaded to the DDBJ, EMBL, and GenBank nucleotide sequence databases under accession numbers AG020727 to AG025611 and AG205093 to AG215049...
  16. doi request reprint Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters
    Mitsuro Kanda
    Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, Nagoya, Japan
    J Surg Oncol 98:190-6. 2008
    ..We investigated correlations of the expression of VEGF-B and its isoforms, VEGF-B167 and VEGF-B186, by alternative splicing in hepatocellular carcinoma (HCC) with the pathological findings and prognosis...