Research Topics
| Shin TakedaSummaryAffiliation: University of Geneva Country: Switzerland Publications
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Detail Information
Publications
DNA methylation and epigenetic inheritance during plant gametogenesisShin Takeda
Laboratory of Plant Genetics, University of Geneva, Science III, Switzerland
Chromosoma 115:27-35. 2006..DME opposes transcriptional silencing associated with imprinting activities of the MEA/FIE polycomb group complex...
BRU1, a novel link between responses to DNA damage and epigenetic gene silencing in ArabidopsisShin Takeda
Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland
Genes Dev 18:782-93. 2004....- Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinomaToshiaki Mori
Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Liver Int 25:380-8. 2005..RUNX3 locus 1p36 is commonly deleted in a variety of human cancers, including HCC. Therefore, we examined genetic and epigenetic alterations of RUNX3 in human HCC... - Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancerMitsuru Sakai
Department of Surgery II, Nagoya University School of Medicine, Showa-ku, Nagoya 466-8560, Japan
Cancer Sci 95:588-91. 2004..Our results suggest that the aberrant methylation of CDH13 occurs frequently in pancreatic cancer, even at a relatively early stage... - Transcriptional activation mediated by binding of a plant GATA-type zinc finger protein AGP1 to the AG-motif (AGATCCAA) of the wound-inducible Myb gene NtMyb2Kazuhiko Sugimoto
Department of Molecular Genetics, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305-8602, Japan
Plant J 36:550-64. 2003..We also found that the AGP1 binding activity is highly enhanced by adenine methylation of the AG-motif by bacterial dam methylase... - Chromatin assembly factor 1 ensures the stable maintenance of silent chromatin states in ArabidopsisTatsuya Ono
Department of Integrated Genetics, National Institute of Genetics, Mishima 411 8540, Japan
Genes Cells 11:153-62. 2006..Furthermore, TGS of the silent beta-glucuronidase (GUS) transgene was also de-repressed randomly in fas. We conclude that CAF-1 ensures the stable inheritance of epigenetic states through growth and development in Arabidopsis... - Aberrant methylation of the CHFR gene in advanced hepatocellular carcinomaMitsuru Sakai
Department of Surgery II, Graduate School of Medicine, Nagoya University, Japan
Hepatogastroenterology 52:1854-7. 2005..037). CONCLUSIONS: Aberrant methylation of the CHFR gene is significantly correlated with the progression of HCC, suggesting that CHFR methylation might be a novel molecular marker to estimate the malignancy of this disease... - Overexpression of pituitary tumor transforming gene 1 in HCC is associated with angiogenesis and poor prognosisTsutomu Fujii
Department of Surgery II, Graduate School and Faculty of Medicine, Nagoya University, Nagoya, Japan
Hepatology 43:1267-75. 2006..PTTG1 is overexpressed in HCC and our results suggest that PTTG1 mRNA expression has prognostic significance for the survival of postoperative patients with HCC... - Frequent promoter methylation of M-cadherin in hepatocellular carcinoma is associated with poor prognosisSuguru Yamada
Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Anticancer Res 27:2269-74. 2007..Many cadherins (CDH) are associated with various types of cancer and their genetic and epigenetic alterations might be involved in carcinogenesis... - [Genetic detection and clinical applications in patients with hepatocellular carcinoma]Shin Takeda
Department of Gastroenterological Surgery (Surgery II, Nagoya University Graduate School of Medicine, Nagoya, Japan
Nippon Geka Gakkai Zasshi 103:472-5. 2002..In future, HCC-specific genes and genes sensitive to radiation and chemotherapy are expected to have wide-spread clinical applications... - Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factorTsutomu Fujii
Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan
J Hepatol 41:104-11. 2004..CONCLUSIONS: Our results suggest that FAK mRNA expression has prognostic significance for the survival of patients with HCC... - An overview of gibberellin metabolism enzyme genes and their related mutants in riceTomoaki Sakamoto
Field Production Science Center, University of Tokyo, Nishi-Tokyo, Tokyo 188-0002, Japan
Plant Physiol 134:1642-53. 2004.... - Biochemical analysis of long terminal repeat retrotransposonsAndreas Bachmair
Max Planck Institute for Plant Breeding Research, Cologne, Germany
Methods Mol Biol 260:73-82. 2004..References include some older key publications that may not be easily accessible via electronic databases. Methods for enrichment of viruslike particles from plant material and from yeast are described... - Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosisOsamu Okochi
Second Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan
Clin Cancer Res 9:5295-8. 2003..Recently, it was demonstrated that SOCS-1 gene was silenced frequently by methylation of CpG island in human hepatocellular carcinoma (HCC). We examined the methylation-mediated silencing of SOCS-1 in tumors of HCC patients... - Target site specificity of the Tos17 retrotransposon shows a preference for insertion within genes and against insertion in retrotransposon-rich regions of the genomeAkio Miyao
Molecular Genetics Department, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305-8602, Japan
Plant Cell 15:1771-80. 2003..The nucleotide sequence data were uploaded to the DDBJ, EMBL, and GenBank nucleotide sequence databases under accession numbers AG020727 to AG025611 and AG205093 to AG215049... 
Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parametersMitsuro Kanda
Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, Nagoya, Japan
J Surg Oncol 98:190-6. 2008..We investigated correlations of the expression of VEGF-B and its isoforms, VEGF-B167 and VEGF-B186, by alternative splicing in hepatocellular carcinoma (HCC) with the pathological findings and prognosis...