Research Topics
Genomes and GenesSpecies | D StolzSummaryAffiliation: University Hospital Country: Switzerland Publications
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Publications
Aspergillus-PCR in bronchoalveolar lavage for detection of invasive pulmonary aspergillosis in immunocompromised patientsMichael Buess
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Basel, Switzerland
BMC Infect Dis 12:237. 2012..We evaluated the diagnostic accuracy of conventional nested PCR in the bronchoalveolar fluid to diagnose IFD in severely immunocompromised patients...
Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]Mirjam Christ-Crain
Department of Internal Medicine, University Hospital Basel, Switzerland
Crit Care 10:R96. 2006..A major cause of sepsis is community-acquired pneumonia (CAP). The aim of this study was to investigate the value of proADM levels for severity assessment and outcome prediction in CAP...
Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumoniaBeat Muller
Departments of Internal Medicine, University Hospital, Petersgraben 4, CH 4031, Basel, Switzerland
BMC Infect Dis 7:10. 2007..This study aims to evaluate the diagnostic and prognostic accuracy of clinical signs and symptoms and laboratory biomarkers for CAP...
Copeptin, C-reactive protein, and procalcitonin as prognostic biomarkers in acute exacerbation of COPDDaiana Stolz
Clinic of Pneumology and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
Chest 131:1058-67. 2007....
Airway reactivity to inhaled mannitol in cigarette smokers: a longitudinal studyDaiana Stolz
Pulmonary Medicine and Respiratory Cell Research and Hospital Pharmacy, University Hospital Basel, Switzerland
Respir Med 101:1470-6. 2007..AHR to mannitol is quite common in smokers compared to non-smokers and decreases significantly after smoking cessation. Thus, the mannitol test may be sensitive to non-asthmatic inflammation of the airways...
Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapyDaiana Stolz
Clinics of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland
Chest 131:9-19. 2007..We evaluated the efficacy and safety of procalcitonin guidance compared to standard therapy with antibiotic prescriptions in patients experiencing exacerbations of COPD...
BAL neutrophils, serum procalcitonin, and C-reactive protein to predict bacterial infection in the immunocompromised hostDaiana Stolz
University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 132:504-14. 2007....
Diagnostic value of signs, symptoms and laboratory values in lower respiratory tract infectionDaiana Stolz
Division of Pulmonary Medicine and Cell Research, University of Basel, Basel, Switzerland
Swiss Med Wkly 136:434-40. 2006..Using the outcome and microbiology findings as gold standard, we determined sensitivity, specificity, positive and negative predictive values of common used signs and symptoms of bacterial LRTI requiring antibiotic therapy...
A randomised, controlled trial of bosentan in severe COPDD Stolz
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
Eur Respir J 32:619-28. 2008....
Propofol versus combined sedation in flexible bronchoscopy: a randomised non-inferiority trialD Stolz
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
Eur Respir J 34:1024-30. 2009..460). Propofol is as effective and safe as combined sedation in patients undergoing flexible bronchoscopy, thus representing an appealing option if timely discharge is a priority...
Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised studyD Stolz
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
Eur Respir J 34:1364-75. 2009..Serum procalcitonin reduces antibiotic therapy exposure in patients with ventilator associated pneumonia...
Enhanced didactic methods of smoking cessation training for medical students--a randomized studyDaiana Stolz
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
Nicotine Tob Res 14:224-8. 2012..It is essential that medical students are adequately trained in smoking cessation. A web-based tobacco abstinence training program might supplement or replace traditional didactic methods...
Use of B-type natriuretic peptide in the risk stratification of community-acquired pneumoniaM Christ-Crain
Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
J Intern Med 264:166-76. 2008..Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Risk stratification has previously been difficult...
Midregional pro-atrial natriuretic peptide and procalcitonin improve survival prediction in VAPL Boeck
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
Eur Respir J 37:595-603. 2011..895 and 0.880). We conclude that the combination of two biomarkers, MR-proANP and PCT, improve survival prediction of clinical severity scores in VAP...
Predicting mortality with pneumonia severity scores: importance of model recalibration to local settingsP Schuetz
University Hospital Basel, Department of Internal Medicine, Basel, Switzerland
Epidemiol Infect 136:1628-37. 2008....
Circulating levels of copeptin, a novel biomarker, in lower respiratory tract infectionsB Muller
University Hospital Basel, Switzerland
Eur J Clin Invest 37:145-52. 2007..Lower respiratory tract infections (LRTI) are a precursor of sepsis. Thus, we investigated circulating levels and the prognostic use of copeptin for the severity and outcome in patients with LRTI...
Circulating levels of pro-atrial natriuretic peptide in lower respiratory tract infectionsB Muller
Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
J Intern Med 260:568-76. 2006..To analyse the mid region of plasma N-terminal pro-atrial natriuretic peptide (MR-proANP) levels in patients with lower respiratory tract infections to evaluate its prognostic use for the severity of disease and outcome...
Use of B-type natriuretic peptide in the risk stratification of acute exacerbations of COPDDaiana Stolz
Clinic for Pneumology and Respiratory Cell Research, University Hospital Basel, Switzerland
Chest 133:1088-94. 2008..In patients with COPD, prognosis might be determined at least in part by the extent of cardiac stress induced by hypoxia and pulmonary arterial hypertension...
Cough suppression during flexible bronchoscopy using combined sedation with midazolam and hydrocodone: a randomised, double blind, placebo controlled trialD Stolz
Division of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland
Thorax 59:773-6. 2004..A randomised, placebo controlled, double blind study was undertaken to determine whether hydrocodone in combination with midazolan improves cough suppression during FB without increasing the risk of desaturation...
Respiratory symptoms, atopy and bronchial hyperreactivity in professional firefightersD Miedinger
Department of Internal Medicine, University Hospital, 4031 Basel, Switzerland
Eur Respir J 30:538-44. 2007..It remains unclear whether these findings were present at recruitment or developed after joining the workforce...
Propofol versus propofol plus hydrocodone for flexible bronchoscopy: a randomised studyL Schlatter
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Basel, Switzerland
Eur Respir J 38:529-37. 2011..The duration of the procedure, time to discharge and complication rate were similar in both groups. The combination of propofol and hydrocodone is safe and superior to propofol alone for cough suppression in flexible bronchoscopy...
A randomized, placebo-controlled trial of bronchodilators for bronchoscopy in patients with COPDDaiana Stolz
Department of Pulmonary, Allergy and Critical Care Medicine, University of Massachusetts Memorial Hospital, 55 Lake Ave N, Worcester, MA 01655, USA
Chest 131:765-72. 2007..We therefore performed a randomized, double-blind, placebo-controlled trial to determine whether use of a short-acting bronchodilator provides a protective effect in patients with COPD undergoing bronchoscopy...
Bronchoscopic lung volume reduction--current opinionMichael Tamm
Clinic of Pneumology and Respiratory Cell Research, University Hospital Basel, Switzerland
Swiss Med Wkly 140:w13140. 2010..This article discusses newest developments and results in bronchoscopic lung volume reduction...
Feasibility and safety of propofol sedation in flexible bronchoscopyPeter Grendelmeier
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Basel, Switzerland
Swiss Med Wkly 141:w13248. 2011..There are only limited data evaluating propofol for flexible bronchoscopy. We analysed the feasibility and safety of propofol for bronchoscopy in a high output tertiary care centre...
Prediction of treatment-response to inhaled corticosteroids by mannitol-challenge test in COPD. A proof of conceptJorg D Leuppi
Pneumology, Department of Internal Medicine, University Hospital, Petersgraben 4, Basel CH 4031, Switzerland
Pulm Pharmacol Ther 18:83-8. 2005..There are no predictors known that can identify COPD patients who will respond to treatment with ICS...
Sedative drug requirements during flexible bronchoscopyPrashant N Chhajed
Pulmonary Medicine, University Hospital Basel, Petersgraben 4, CH 1031 Basel, Switzerland
Respiration 72:617-21. 2005..There is a paucity of data comparing doses of sedative medication during bronchoscopy in immunosuppressed and non-immunosuppressed patients...
Discriminate use of antibiotics for exacerbation of COPDDaiana Stolz
Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, Basel CH 4031, Switzerland
Curr Opin Pulm Med 15:126-32. 2009....
Reliability and validity of a German asthma quality of life questionnaireDavid Miedinger
Department of Internal Medicine, University Hospital, Basel, Switzerland
Swiss Med Wkly 136:89-95. 2006..The German translation of the AQLQ-Sydney had a good internal consistency and test-retest-reliability in stable asthmatic patients. It shows responsiveness to treatment. Some correlations with objective markers were detected...
Diagnostic tests for asthma in firefightersDavid Miedinger
Clinic for Pneumology, University Hospital, Basel, Switzerland
Chest 131:1760-7. 2007..Subjects with asthma do not meet medical requirements for professions such as firefighting...
Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPDDaiana Stolz
Clinic of Pneumology, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
Chest 134:263-72. 2008..We investigated whether plasma pro-endothelin-1 (proET-1) and/or pro-adrenomedullin (proADM) on admission to the hospital for acute exacerbation predict survival in patients with COPD...
Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumoniaPhilipp Schuetz
Department of Internal Medicine, University Hospital Basel, Switzerland
BMC Infect Dis 8:22. 2008..The objective of this study was to assess the diagnostic and prognostic value of proET-1 in a prospective cohort of mainly septic patients with community-acquired pneumonia...
Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trialMirjam Christ-Crain
Department of Internal Medicine, University Hospital, Basel, Switzerland
Am J Respir Crit Care Med 174:84-93. 2006..In patients with community-acquired pneumonia, guidelines recommend antibiotic treatment for 7 to 21 d. Procalcitonin is elevated in bacterial infections, and its dynamics have prognostic implications...
Nebulized lidocaine for flexible bronchoscopy: a randomized, double-blind, placebo-controlled trialDaiana Stolz
Division of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
Chest 128:1756-60. 2005..We performed a prospective, randomized, double-blind, placebo-controlled trial to evaluate whether nebulized lidocaine provides additional benefit and reduces the total anesthetic dose required during bronchoscopy...
Perimenstrual increase in bronchial hyperreactivity in premenopausal women: results from the population-based SAPALDIA 2 cohortJulia Dratva
Institute of Social and Preventive Medicine at the Swiss Tropical Institute, Basel, Switzerland
J Allergy Clin Immunol 125:823-9. 2010..Studies on perimenstrual asthma are inconsistent, and different methodologies limit comparisons...
Prognostic impact of plasma lipids in patients with lower respiratory tract infections - an observational studyMaja Gruber
Clinic of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, Basel, Switzerland
Swiss Med Wkly 139:166-72. 2009..Whether lipids have prognostic implications or could help to differentiate community-acquired pneumonia from other lower respiratory tract infections remains unknown...
Pancreatic stone protein: a marker of organ failure and outcome in ventilator-associated pneumoniaLucas Boeck
Clinic of Pulmonary Medicine and Respiratory Cell Research, University Hospital Basel, Basel, Switzerland
Chest 140:925-32. 2011..The prognostic value of PSP/reg among critically ill patients is unknown. The aim of this pilot study was to evaluate PSP/reg in VAP...
Circulating levels of soluble triggering receptor expressed on myeloid cells (sTREM)-1 in community-acquired pneumoniaBeat Muller
Crit Care Med 35:990-1. 2007
Free and total cortisol levels as predictors of severity and outcome in community-acquired pneumoniaMirjam Christ-Crain
Department of Endocrinology, William Harvey Research Institute, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, United Kingdom
Am J Respir Crit Care Med 176:913-20. 2007..Whether FC concentrations better reflect outcome is uncertain. Objectives: To investigate the predictive value of TC and FC in community-acquired pneumonia (CAP)...
