Affiliation: University of Zurich
- Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell deathAttila Stetak
Department of Molecular Biology, Max Planck Institute for Biochemistry, Martinsried, Germany
Cancer Res 67:1602-8. 2007..These results show that the tumor marker PKM2 plays a general role in caspase-independent cell death of tumor cells and thereby defines this glycolytic enzyme as a novel target for cancer therapy development...