Monika Østensen

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi Management of early aggressive rheumatoid arthritis during pregnancy and lactation
    Monika Ostensen
    Department of Rheumatology, and Clinical Immunology and Allergy, University Hospital, CH 3010 Bern, Switzerland
    Expert Opin Pharmacother 10:1469-79. 2009
  2. ncbi Disease specific problems related to drug therapy in pregnancy
    M Ostensen
    Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Berne, Switzerland
    Lupus 13:746-50. 2004
  3. ncbi Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus
    M Ostensen
    Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Berne, Berne, Switzerland
    Lupus 9:566-72. 2000
  4. doi Update on safety during pregnancy of biological agents and some immunosuppressive anti-rheumatic drugs
    M Østensen
    Department of Rheumatology and Clinical Immunology and Allergology, University Hospital of Bern, CH 3010 Bern, Switzerland
    Rheumatology (Oxford) 47:iii28-31. 2008
  5. doi Management of RA medications in pregnant patients
    Monika Østensen
    Department of Rheumatology, Clinical Immunology and Allergology, University Hospital Bern, Bern, Switzerland
    Nat Rev Rheumatol 5:382-90. 2009
  6. ncbi The remission of rheumatoid arthritis during pregnancy
    Monika Ostensen
    Clinic for Rheumatology and Clinical Immunology, University Hospital of Berne, CH 3010 Bern, Switzerland
    Semin Immunopathol 29:185-91. 2007
  7. ncbi Therapy insight: the use of antirheumatic drugs during nursing
    Monika Østensen
    Center for Women with Rheumatic Disease, Department of Rheumatology, University Hospital of Bern, Bern, Switzerland
    Nat Clin Pract Rheumatol 3:400-6. 2007
  8. ncbi Therapy with immunosuppressive drugs and biological agents and use of contraception in patients with rheumatic disease
    Monika Østensen
    Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
    J Rheumatol 34:1266-9. 2007
  9. ncbi Cytokines and pregnancy in rheumatic disease
    Monika Østensen
    Department of Rheumatology and Clinical Immunology and Allergy, University Hospital, CH 3010 Bern, Switzerland
    Ann N Y Acad Sci 1069:353-63. 2006
  10. pmc Anti-inflammatory and immunosuppressive drugs and reproduction
    Monika Østensen
    Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
    Arthritis Res Ther 8:209. 2006

Detail Information

Publications26

  1. doi Management of early aggressive rheumatoid arthritis during pregnancy and lactation
    Monika Ostensen
    Department of Rheumatology, and Clinical Immunology and Allergy, University Hospital, CH 3010 Bern, Switzerland
    Expert Opin Pharmacother 10:1469-79. 2009
    ..Judicious timing of therapy is therefore necessary, aiming at fast remission of symptoms with the most effective therapy and maintaining quiescent disease with drugs compatible with pregnancy or lactation...
  2. ncbi Disease specific problems related to drug therapy in pregnancy
    M Ostensen
    Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Berne, Switzerland
    Lupus 13:746-50. 2004
    ..Prepregnancy counselling and careful monitoring during pregnancy help to tailor necessary drug treatment for the benefit of mother and child...
  3. ncbi Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus
    M Ostensen
    Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Berne, Berne, Switzerland
    Lupus 9:566-72. 2000
    ..In summary, treatment of SLE with NSAID requires awareness for the increased frequency of some side effects and close monitoring of toxicity...
  4. doi Update on safety during pregnancy of biological agents and some immunosuppressive anti-rheumatic drugs
    M Østensen
    Department of Rheumatology and Clinical Immunology and Allergology, University Hospital of Bern, CH 3010 Bern, Switzerland
    Rheumatology (Oxford) 47:iii28-31. 2008
    ..Prophylactic withdrawal of drugs before pregnancy is mandatory for abatacept, rituximab, LEF and MMF. Data remain insufficient for gonadal toxicity of immunosuppressive drugs in men and for excretion of these drugs in human breast milk...
  5. doi Management of RA medications in pregnant patients
    Monika Østensen
    Department of Rheumatology, Clinical Immunology and Allergology, University Hospital Bern, Bern, Switzerland
    Nat Rev Rheumatol 5:382-90. 2009
    ..The most important consideration when managing rheumatoid arthritis medications during pregnancy is that therapy must be tailored for the individual patient according to disease activity...
  6. ncbi The remission of rheumatoid arthritis during pregnancy
    Monika Ostensen
    Clinic for Rheumatology and Clinical Immunology, University Hospital of Berne, CH 3010 Bern, Switzerland
    Semin Immunopathol 29:185-91. 2007
    ..The complex hormonal and immunological alterations of pregnancy may temporarily correct the disturbed immunregulation of RA...
  7. ncbi Therapy insight: the use of antirheumatic drugs during nursing
    Monika Østensen
    Center for Women with Rheumatic Disease, Department of Rheumatology, University Hospital of Bern, Bern, Switzerland
    Nat Clin Pract Rheumatol 3:400-6. 2007
    ..At present, many patients feel they have to choose between postpartum disease control and lactation. Extended studies of the transfer of antirheumatic drugs into breast milk and the resulting consequences are, therefore, urgently needed...
  8. ncbi Therapy with immunosuppressive drugs and biological agents and use of contraception in patients with rheumatic disease
    Monika Østensen
    Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
    J Rheumatol 34:1266-9. 2007
    ..To investigate the attitude of patients towards immunosuppressive and biological drugs in relation to reproduction and the outcome of pregnancies exposed to these drugs...
  9. ncbi Cytokines and pregnancy in rheumatic disease
    Monika Østensen
    Department of Rheumatology and Clinical Immunology and Allergy, University Hospital, CH 3010 Bern, Switzerland
    Ann N Y Acad Sci 1069:353-63. 2006
    ..The influence of hormones and cytokines on autoimmune disease is an issue for further study...
  10. pmc Anti-inflammatory and immunosuppressive drugs and reproduction
    Monika Østensen
    Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
    Arthritis Res Ther 8:209. 2006
    ..Recommendations for drug treatment during pregnancy and lactation are given...
  11. ncbi [Antirheumatic therapy and reproduction. The influence on fertility, pregnancy and breast feeding]
    M Ostensen
    Klinik für Rheumatologie und Klinische Immunologie Allergologie, Inselspital Bern, Universitatsklinik, Bern
    Z Rheumatol 65:217-20, 222-4. 2006
    ..Treatment with immunosuppressive drugs during lactation is limited because of insufficient documentation of safety for the breastfed child...
  12. ncbi Glucocorticosteroids in pregnant patients with rheumatoid arthritis
    M Ostensen
    Clinic for Rheumatology and Clinical Immunology, University Hospital of Berne, CH 3010 Bern, Switzerland
    Z Rheumatol 59:II/70-4. 2000
    ..The complex hormonal and immunological alterations of pregnancy may temporarily correct the neuroendocrine defects. The precise role of glucocorticoids in pregnancy-induced remission of RA still needs to be clarified...
  13. ncbi Immunology of pregnancy-pregnancy as a remission inducing agent in rheumatoid arthritis
    Monika Ostensen
    Department of Rheumatology, Clinical Immunology and Allergy University Hospital of Berne, Switzerland
    Transpl Immunol 9:155-60. 2002
    ..It remains to be investigated if a single event like neutralisation of proinflammatory cytokines or an interplay between circulating and cellular mechanisms is the key to remission...
  14. ncbi Perinatal outcome of pregnancies in women with connective tissue disease
    M Ostensen
    Department of Rheumatology and Clinical Immunology, University Hospital, Berne, Switzerland
    Lupus 11:661. 2002
  15. ncbi New insights into sexual functioning and fertility in rheumatic diseases
    Monika Østensen
    Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Berne, CH 3010 Bern, Switzerland
    Best Pract Res Clin Rheumatol 18:219-32. 2004
    ..Active disease disturbs the hypothalamic-pituitary-axis, giving rise to periods of gonadal dysfunction. Toxic effects of immunosuppressive drugs can induce transient or permanent gonadal failure in women and men...
  16. pmc A prospective study of pregnant patients with rheumatoid arthritis and ankylosing spondylitis using validated clinical instruments
    M Østensen
    Department of Rheumatology and Clinical Immunology and Allergy, University Hospital, CH 3010 Bern, Switzerland
    Ann Rheum Dis 63:1212-7. 2004
    ....
  17. pmc Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum
    M Østensen
    Department of Rheumatology and Clinical Immunology and Allergy, University Hospital, CH 3010 Bern, Switzerland
    Ann Rheum Dis 64:839-44. 2005
    ..To investigate changes in the levels of circulating cytokines with a focus on the Th1/Th2 balance during and after pregnancy in patients with rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), and ankylosing spondylitis (AS)...
  18. pmc Activation markers of peripheral blood mononuclear cells in late pregnancy and after delivery: a pilot study
    M Østensen
    Department of Rheumatology and Clinical Immunology, University Hospital, CH 3010 Bern, Switzerland
    Ann Rheum Dis 64:318-20. 2005
    ..To study the putative shift of a Th1 to a Th2 immune response in pregnancy and its reversal post partum in healthy women and patients with rheumatoid arthritis (RA)...
  19. doi Interaction of pregnancy and autoimmune rheumatic disease
    Monika Østensen
    Department of Rheumatology and Clinical Immunology and Allergology, University Hospital, Bern, Switzerland
    Autoimmun Rev 11:A437-46. 2012
    ....
  20. doi Effects of TNF antagonists on sperm characteristics in patients with spondyloarthritis
    Peter M Villiger
    Department of Rheumatology, Clinical Immunology and Allergology, University Hospital and University of Bern, CH 3010 Bern, Switzerland
    Ann Rheum Dis 69:1842-4. 2010
    ..To study the influence of tumour necrosis factor (TNF) antagonists on spermatogenesis in a cohort of patients with spondyloarthritis (SpA)...
  21. doi Pregnancy mediated improvement of rheumatoid arthritis
    Frauke Förger
    Department of Rheumatology, Clinical Immunology and Allergology, University Hospital and University of Bern, Switzerland
    Swiss Med Wkly 142:w13644. 2012
    ..To investigate pregnancy related changes of rheumatoid factor (RF) isotypes and anti-citrullinated protein antibodies (ACPA) and their association with disease activity and therapy in patients with rheumatoid arthritis...
  22. ncbi A woman with rheumatoid arthritis whose condition did not improve during pregnancy
    Monika Østensen
    Department of Rheumatology and Clinical Immunology and Allergology, University of Berne, Switzerland
    Nat Clin Pract Rheumatol 1:111-4; quiz 1 p. following 114. 2005
    ..She was treated with low-dose prednisone, sulfasalazine, nimesulide, and intra-articular corticosteroid injections. Oligohydramnios developed at gestational week 18...
  23. doi Pregnancy in patients with ankylosing spondylitis: do regulatory T cells play a role?
    Frauke Förger
    Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland
    Arthritis Rheum 61:279-83. 2009
    ..To investigate the numerical and functional changes of CD4+CD25(high) regulatory T (Treg) cells during pregnancy and postpartum in patients with ankylosing spondylitis (AS)...
  24. ncbi Clinical diagnosis compared to classification criteria in in a cohort of 54 patients with systemic sclerosis and associated disorders
    Hans Rudolf Ziswiler
    Department of Rheumatology, Clinical Immunology and Allergology, University Hospital, Bern, Switzerland
    Swiss Med Wkly 137:586-90. 2007
    ..To compare clinical diagnosis with two validated classification criteria for systemic sclerosis (SSc) in a cohort of Swiss patients with SSc and associated disorders...
  25. doi Influence of pregnancy on the adipocytokine and peroxisome proliferator-activated receptor pathways in peripheral blood mononuclear cells from healthy donors and rheumatoid arthritis patients
    Janine Weix
    University Hospital and University of Bern, Bern, Switzerland
    Arthritis Rheum 64:2095-103. 2012
    ..To identify candidate genes that are regulated by human pregnancy and have the potential to modulate rheumatoid arthritis (RA) disease activity...
  26. ncbi [Pregnancy in patients with rheumatoid arthritis and inflammatory spondylarthropathies]
    E Gromnica-Ihle
    Rheumapraxis Berlin Pankow, Berlin
    Z Rheumatol 65:209-12, 214-6. 2006
    ..Every pregnancy in women with a rheumatic disease should be considered as high-risk, and such pregnancies require close collaboration between rheumatologists and obstetricians...