Simon G Sprecher
Affiliation: University of Fribourg
Guillermin O, Perruchoud B, Sprecher S, Egger B. Characterization of tailless functions during Drosophila optic lobe formation. Dev Biol. 2015;405:202-13 pubmed publisher
..We propose that the Tll/Tlx transcription factors have an evolutionary conserved role in regulating neural precursor cell states in the Drosophila optic lobe and in the mammalian retina. ..
Humberg T, Bruegger P, Afonso B, Zlatic M, Truman J, Gershow M, et al
. Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues. Nat Commun. 2018;9:1260 pubmed publisher
..Functional features of the larval visual circuit highlight the principle of how early in a sensory circuit distinct behaviors may be computed by partly overlapping sensory pathways. ..
Widmer Y, Bilican A, Bruggmann R, Sprecher S. Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster. Genetics. 2018;209:1167-1181 pubmed publisher
..The presented transcriptomic data may further be used as resource to study genes acting at different memory phases. ..
de Andres Bragado L, Mazza C, Senn W, Sprecher S. Statistical modelling of navigational decisions based on intensity versus directionality in Drosophila larval phototaxis. Sci Rep. 2018;8:11272 pubmed publisher
Bernardo Garcia F, Fritsch C, Sprecher S. The transcription factor Glass links eye field specification with photoreceptor differentiation in Drosophila. Development. 2016;143:1413-23 pubmed publisher
..Together, our results provide a transcriptional link between eye field specification and photoreceptor differentiation in Drosophila, placing Glass at a central position in this developmental process. ..