Affiliation: University of Geneva
- Genetic recombination: sex-change operations in yeastD Shore
Department of Molecular Biology, University of Geneva, 30 Quai Ernest Ansermet, CH 1211 Geneva 4, Switzerland
Curr Biol 7:R24-7. 1997..In MATa cells, a cis-acting 'recombinational enhancer' activates this entire region, while in MATalpha cells the enhancer is turned off by the alpha2 repressor...
- Telomeric chromatin: replicating and wrapping up chromosome endsD Shore
University of Geneva, Switzerland
Curr Opin Genet Dev 11:189-98. 2001....
- Telomere length regulation: coupling DNA end processing to feedback regulation of telomeraseDavid Shore
Department of Molecular Biology and NCCR Program Frontiers in Genetics, University of Geneva, Sciences III, Geneva, Switzerland
EMBO J 28:2309-22. 2009..The emerging picture is that of a complex interplay between the conventional DNA replication machinery, DNA damage response factors, and a specialized set of proteins that help to recruit and regulate the telomerase enzyme...
- Locus specificity determinants in the multifunctional yeast silencing protein Sir2G Cuperus
Department of Molecular Biology, University of Geneva, Geneva 4, CH 1211 Switzerland
EMBO J 19:2641-51. 2000..These results define distinct functional domains of Sir2p and provide evidence for additional Sir2p-interacting factors with locus-specific silencing functions...
- Telomere formation by rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombinationS Grossi
Department of Molecular Biology, University of Geneva, 1211 Geneva 4, Switzerland
Mol Cell Biol 21:8117-28. 2001..Our results provide new insights into the nature of telomere end capping and reveal one way by which recombination can resolve a defect in this process...
- Transcriptional silencing: replication reduxD Shore
Department of Molecular Biology, Sciences II, University of Geneva, 30 quai Ernest-Ansermet, CH-1211, Geneva, Switzerland
Curr Biol 11:R816-9. 2001....