Valerie M Schwitzgebel

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements
    Benoit R Gauthier
    Unite de Diabetologie Clinique, Centre Medical Universitaire, 1211 Geneve 4, Switzerland
    Mol Endocrinol 16:170-83. 2002
  2. ncbi request reprint Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
    Valerie M Schwitzgebel
    Pediatric Endocrinology and Diabetology, Geneva University Hospital, CH 1211 Geneva, Switzerland
    J Clin Endocrinol Metab 88:4398-406. 2003
  3. doi request reprint Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life
    Emmanuel Somm
    Department of Pediatrics, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Endocrinology 149:6289-99. 2008
  4. doi request reprint Prenatal nicotine exposure and the programming of metabolic and cardiovascular disorders
    Emmanuel Somm
    Department of Pediatrics, Geneva University Hospitals, Switzerland
    Mol Cell Endocrinol 304:69-77. 2009
  5. pmc Perinatal exposure to bisphenol a alters early adipogenesis in the rat
    Emmanuel Somm
    Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Environ Health Perspect 117:1549-55. 2009
  6. ncbi request reprint Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function
    Eric Marthinet
    Pediatric Endocrinology and Diabetology, Children s Hospital, 6, rue Willy Donze, CH 1211 Geneva, Switzerland
    J Clin Endocrinol Metab 90:5401-6. 2005

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements
    Benoit R Gauthier
    Unite de Diabetologie Clinique, Centre Medical Universitaire, 1211 Geneve 4, Switzerland
    Mol Endocrinol 16:170-83. 2002
    ..We suggest that HNF-3 may play a dual role on glucagon gene transcription by 1) inhibiting the transactivation potential of Pax6 on the G1 and G3 elements and 2) direct activation through G1 and G2...
  2. ncbi request reprint Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
    Valerie M Schwitzgebel
    Pediatric Endocrinology and Diabetology, Geneva University Hospital, CH 1211 Geneva, Switzerland
    J Clin Endocrinol Metab 88:4398-406. 2003
    ..We conclude that the IPF1 level is critical for human pancreas formation...
  3. doi request reprint Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life
    Emmanuel Somm
    Department of Pediatrics, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Endocrinology 149:6289-99. 2008
    ..These results prove a direct association between fetal nicotine exposure and offspring metabolic syndrome with early signs of dysregulations of adipose tissue and pancreatic development...
  4. doi request reprint Prenatal nicotine exposure and the programming of metabolic and cardiovascular disorders
    Emmanuel Somm
    Department of Pediatrics, Geneva University Hospitals, Switzerland
    Mol Cell Endocrinol 304:69-77. 2009
    ....
  5. pmc Perinatal exposure to bisphenol a alters early adipogenesis in the rat
    Emmanuel Somm
    Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Environ Health Perspect 117:1549-55. 2009
    ..The causes of the current obesity pandemic have not been fully elucidated. Implication of environmental endocrine disruptors such as bisphenol A (BPA) on adipose tissue development has been poorly investigated...
  6. ncbi request reprint Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function
    Eric Marthinet
    Pediatric Endocrinology and Diabetology, Children s Hospital, 6, rue Willy Donze, CH 1211 Geneva, Switzerland
    J Clin Endocrinol Metab 90:5401-6. 2005
    ..A loss of function of K(ATP) channels causes depolarization of beta-cells and congenital hyperinsulinism (CHI), a disease presenting with severe hypoglycemia in the newborn period...