Andre Schaller

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Impairment of mitochondrial tRNAIle processing by a novel mutation associated with chronic progressive external ophthalmoplegia
    A Schaller
    Division of Human Genetics, University Hospital Bern, Switzerland
    Mitochondrion 11:488-96. 2011
  2. ncbi Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome
    Andre Schaller
    Division of Human Genetics, University Hospital Bern, Bern, Switzerland
    BMC Neurol 11:4. 2011
  3. ncbi Quantitative 1-step DNA methylation analysis with native genomic DNA as template
    Thomas von Kanel
    Division of Human Genetics, Department of Pediatrics, Inselspital, University of Bern, Bern, Switzerland
    Clin Chem 56:1098-106. 2010
  4. ncbi Age-dependent suppression of SERCA2a mRNA in pediatric atrial myocardium
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, 3010 Berne, Switzerland
    Biochem Biophys Res Commun 326:344-8. 2005
  5. ncbi Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement
    Martin Konrad
    University Children s Hospital, Inselspital, Bern, Switzerland
    Am J Hum Genet 79:949-57. 2006
  6. ncbi Sodium pump reduction correlates with aortic clamp time in pediatric heart surgery
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, Freiburgstrasse 23, 3010 Berne, Switzerland
    Exp Biol Med (Maywood) 231:1300-5. 2006
  7. ncbi Reduced atrial connexin43 expression after pediatric heart surgery
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, Berne, Switzerland
    Biochem Biophys Res Commun 342:310-5. 2006
  8. ncbi Gender modulates the expression of calcium-regulating proteins in pediatric atrial myocardium
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, Berne, Switzerland
    Exp Biol Med (Maywood) 230:853-9. 2005
  9. ncbi Cardiopulmonary bypass reduces atrial Na+-K+-ATPase expression in children
    Mladen Pavlovic
    Division of Pediatric Cardiology, Department of Pediatrics, University Hospital, 3010 Berne, Switzerland
    Biochem Biophys Res Commun 335:700-4. 2005
  10. ncbi Identification of SNPs in the cystic fibrosis interactome influencing pulmonary progression in cystic fibrosis
    Franziska M Gisler
    Division of Human Genetics, Department of Pediatrics and Clinical Research, University of Bern, Bern, Switzerland
    Eur J Hum Genet 21:397-403. 2013

Detail Information

Publications13

  1. ncbi Impairment of mitochondrial tRNAIle processing by a novel mutation associated with chronic progressive external ophthalmoplegia
    A Schaller
    Division of Human Genetics, University Hospital Bern, Switzerland
    Mitochondrion 11:488-96. 2011
    ..These results suggest that structural perturbations reduce efficiency of tRNA(Ile) precursor 3' end processing and contribute to the molecular pathomechanism of this mutation...
  2. ncbi Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome
    Andre Schaller
    Division of Human Genetics, University Hospital Bern, Bern, Switzerland
    BMC Neurol 11:4. 2011
    ..In compound heterozygote patients the p.A467T mutation has been described to be associated amongst others with fatal childhood encephalopathy. These patients have a poorer survival rate compared to homozygotes...
  3. ncbi Quantitative 1-step DNA methylation analysis with native genomic DNA as template
    Thomas von Kanel
    Division of Human Genetics, Department of Pediatrics, Inselspital, University of Bern, Bern, Switzerland
    Clin Chem 56:1098-106. 2010
    ..To facilitate DNA methylation analysis, we have developed a quantitative 1-step assay for DNA methylation analysis...
  4. ncbi Age-dependent suppression of SERCA2a mRNA in pediatric atrial myocardium
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, 3010 Berne, Switzerland
    Biochem Biophys Res Commun 326:344-8. 2005
    ..Age itself did not influence the SERCA2a and PLB expression, if the hemodynamic overload was not taken into account. This study is the first to show a combined influence of volume overload and age on atrial SERCA2a expression...
  5. ncbi Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement
    Martin Konrad
    University Children s Hospital, Inselspital, Bern, Switzerland
    Am J Hum Genet 79:949-57. 2006
    ....
  6. ncbi Sodium pump reduction correlates with aortic clamp time in pediatric heart surgery
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, Freiburgstrasse 23, 3010 Berne, Switzerland
    Exp Biol Med (Maywood) 231:1300-5. 2006
    ..In contrast, only dilated right atrium seemed to be susceptible to CPB in terms of sodium pump expression, showing a reduction during the operation and a correlation of sodium pump with postoperative troponin-I values...
  7. ncbi Reduced atrial connexin43 expression after pediatric heart surgery
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, Berne, Switzerland
    Biochem Biophys Res Commun 342:310-5. 2006
    ..006) and Cx43 higher (p=0.017) expressed, without significant change during CPB. This study revealed a significant influence of CPB and the underlying heart defect on Cx43 expression...
  8. ncbi Gender modulates the expression of calcium-regulating proteins in pediatric atrial myocardium
    Mladen Pavlovic
    Division of Pediatric Cardiology, University Children s Hospital, Berne, Switzerland
    Exp Biol Med (Maywood) 230:853-9. 2005
    ..To our knowledge, this study is the first to show the impact of gender on the differential expression of calcium-regulating components in pediatric cardiac patients...
  9. ncbi Cardiopulmonary bypass reduces atrial Na+-K+-ATPase expression in children
    Mladen Pavlovic
    Division of Pediatric Cardiology, Department of Pediatrics, University Hospital, 3010 Berne, Switzerland
    Biochem Biophys Res Commun 335:700-4. 2005
    ..This seemed to be an early molecular event, as apart from one, none of the patients showed heart failure before or after surgery...
  10. ncbi Identification of SNPs in the cystic fibrosis interactome influencing pulmonary progression in cystic fibrosis
    Franziska M Gisler
    Division of Human Genetics, Department of Pediatrics and Clinical Research, University of Bern, Bern, Switzerland
    Eur J Hum Genet 21:397-403. 2013
    ..Phe508del-CFTR while variants in KRT19 may modulate the amount of p.Phe508del-CFTR at the apical membrane and consequently modify CF disease...
  11. ncbi qPCR-based mitochondrial DNA quantification: influence of template DNA fragmentation on accuracy
    Christopher B Jackson
    Division of Human Genetics, Departement of Pediatrics, Inselspital, University of Berne, Freiburgstrasse, CH 3010 Berne, Switzerland
    Biochem Biophys Res Commun 423:441-7. 2012
    ..To our knowledge this is the first time different degradation impact of the two genomes is demonstrated and which evaluates systematically the impact of DNA degradation on quantification of mtDNA copy number...
  12. ncbi Rapid typing of Moraxella catarrhalis subpopulations based on outer membrane proteins using mass spectrometry
    Andre Schaller
    Division of Human Genetics, University of Bern, Friedbuehlstrasse 51, CH 3010 Bern, Switzerland
    Proteomics 6:172-80. 2006
    ..catarrhalis isolates to the correct subpopulation. Therefore, MALDI-TOF of intact M. catarrhalis provides a rapid and robust tool for M. catarrhalis strain typing that could be applied in epidemiological studies...
  13. ncbi The CFTR frameshift mutation 3905insT and its effect at transcript and protein level
    Javier Sanz
    Department of Paediatrics, Division of Human Genetics, University of Bern, Bern, Switzerland
    Eur J Hum Genet 18:212-7. 2010
    ..However, further experiments are needed to elucidate the fate of the 3905insT CFTR in the cell after its biosynthesis...