Reinhard Saller

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi request reprint [Multimorbidity and multi-target-therapy with herbal drugs]
    R Saller
    Institut für Naturheilkunde, Universitatsspital Zurich
    Praxis (Bern 1994) 101:1637-42. 2012
  2. doi request reprint [Antiinflammatory herbal drugs and their therapeutic potential in tumor patients]
    Reinhard Saller
    Institut für Naturheilkunde, Universitatsspital, Zurich, Schweiz
    Forsch Komplementmed 18:203-12. 2011
  3. doi request reprint An updated systematic review with meta-analysis for the clinical evidence of silymarin
    Reinhard Saller
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
    Forsch Komplementmed 15:9-20. 2008
  4. ncbi request reprint An updated systematic review of the pharmacology of silymarin
    Reinhard Saller
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
    Forsch Komplementmed 14:70-80. 2007
  5. ncbi request reprint Comparison of the growth-inhibitory effect of Hypericum perforatum L. extracts, differing in the concentration of phloroglucinols and flavonoids, on leukaemia cells
    Katarina Hostanska
    Department of Internal Medicine F NUK 104, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    J Pharm Pharmacol 55:973-80. 2003
  6. ncbi request reprint Apoptosis of human prostate androgen-dependent and -independent carcinoma cells induced by an isopropanolic extract of black cohosh involves degradation of cytokeratin (CK) 18
    Katarina Hostanska
    Department of Internal Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    Anticancer Res 25:139-47. 2005
  7. ncbi request reprint Inhibitory effect of an isopropanolic extract of black cohosh on the invasiveness of MDA-mB 231 human breast cancer cells
    Katarina Hostanska
    Department of Internal Medicine, Institute for Complementary Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    In Vivo 21:349-55. 2007
  8. ncbi request reprint Evaluation of cell death caused by an ethanolic extract of Serenoae repentis fructus (Prostasan) on human carcinoma cell lines
    Katarina Hostanska
    University Hospital Zurich, Department of Internal Medicine, Institute for Complementary Medicine, Ramistrasse 100, 8091 Zurich, Switzerland
    Anticancer Res 27:873-81. 2007
  9. ncbi request reprint [Clinical studies in peripheral arterial occlusive disease: update from the aspects of a meta-narrative review]
    Jörg Melzer
    Institut für Naturheilkunde, Universitatsspital Zurich, Schweiz
    Forsch Komplementmed 20:17-21. 2013
  10. ncbi request reprint Treating intermittent claudication with Tibetan medicine Padma 28: does it work?
    Jörg Melzer
    Department of Internal Medicine, Complementary Medicine, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
    Atherosclerosis 189:39-46. 2006

Detail Information

Publications37

  1. doi request reprint [Multimorbidity and multi-target-therapy with herbal drugs]
    R Saller
    Institut für Naturheilkunde, Universitatsspital Zurich
    Praxis (Bern 1994) 101:1637-42. 2012
    ..However, at present there is still a great need and demand for therapy-oriented clinical research...
  2. doi request reprint [Antiinflammatory herbal drugs and their therapeutic potential in tumor patients]
    Reinhard Saller
    Institut für Naturheilkunde, Universitatsspital, Zurich, Schweiz
    Forsch Komplementmed 18:203-12. 2011
  3. doi request reprint An updated systematic review with meta-analysis for the clinical evidence of silymarin
    Reinhard Saller
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
    Forsch Komplementmed 15:9-20. 2008
    ..The potential benefit of silymarin (special extract from the fruits of Silybum marianum) in the treatment of liver diseases remains a controversial issue...
  4. ncbi request reprint An updated systematic review of the pharmacology of silymarin
    Reinhard Saller
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
    Forsch Komplementmed 14:70-80. 2007
    ..Recent years have seen an explosion of scientific papers that deal with drugs from the fruits of milk thistle and its active substances silymarin (standardized mixture of flavonolignanes), thus justifying an updated systematic review...
  5. ncbi request reprint Comparison of the growth-inhibitory effect of Hypericum perforatum L. extracts, differing in the concentration of phloroglucinols and flavonoids, on leukaemia cells
    Katarina Hostanska
    Department of Internal Medicine F NUK 104, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    J Pharm Pharmacol 55:973-80. 2003
    ..5 microM flavonoids. The results of this study supported the hypothesis that, apart from hyperforin and flavonoids, other components of the extract could be involved in its growth-inhibitory effect that it exerts without light activation...
  6. ncbi request reprint Apoptosis of human prostate androgen-dependent and -independent carcinoma cells induced by an isopropanolic extract of black cohosh involves degradation of cytokeratin (CK) 18
    Katarina Hostanska
    Department of Internal Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    Anticancer Res 25:139-47. 2005
    ..The cell growth inhibitory effect of an isopropanolic extract of black cohosh (iCR) on androgen-sensitive LNCaP and androgen-insensitive PC-3 and DU 145 prostate cancer cells was investigated...
  7. ncbi request reprint Inhibitory effect of an isopropanolic extract of black cohosh on the invasiveness of MDA-mB 231 human breast cancer cells
    Katarina Hostanska
    Department of Internal Medicine, Institute for Complementary Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    In Vivo 21:349-55. 2007
    ..To broaden observations, the anti-invasive effects of iCR and its two major fractions triterpene glycosides (TTG) and cinnamic acid esters (CAE) were tested in highly invasive MDA-MB 231 cells...
  8. ncbi request reprint Evaluation of cell death caused by an ethanolic extract of Serenoae repentis fructus (Prostasan) on human carcinoma cell lines
    Katarina Hostanska
    University Hospital Zurich, Department of Internal Medicine, Institute for Complementary Medicine, Ramistrasse 100, 8091 Zurich, Switzerland
    Anticancer Res 27:873-81. 2007
    ..The lipido-sterolic extract of the fruit of Serenoa repens is one of the more widely used phytotherapeutic agents in this regard...
  9. ncbi request reprint [Clinical studies in peripheral arterial occlusive disease: update from the aspects of a meta-narrative review]
    Jörg Melzer
    Institut für Naturheilkunde, Universitatsspital Zurich, Schweiz
    Forsch Komplementmed 20:17-21. 2013
    ..In the planning of the therapy, information about evidence of the interventions and a rationale for reasonable combinations are important...
  10. ncbi request reprint Treating intermittent claudication with Tibetan medicine Padma 28: does it work?
    Jörg Melzer
    Department of Internal Medicine, Complementary Medicine, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
    Atherosclerosis 189:39-46. 2006
    ..e. walking distance), probably of the same order of magnitude as other employed medications. However, larger confirmatory RCTs are desirable...
  11. ncbi request reprint Systematic review of clinical data with BNO-101 (Sinupret) in the treatment of sinusitis
    Jörg Melzer
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Forsch Komplementmed 13:78-87. 2006
    ..This paper reviews the clinical evidence of BNO-101 in sinusitis...
  12. pmc A homeopathic remedy from arnica, marigold, St. John's wort and comfrey accelerates in vitro wound scratch closure of NIH 3T3 fibroblasts
    Katarina Hostanska
    Institute for Complementary Medicine, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland
    BMC Complement Altern Med 12:100. 2012
    ..The objective of this study was to investigate the effect of a commercial low potency homeopathic remedy Similasan® Arnica plus Spray on wound closure in a controlled, blind trial in vitro...
  13. doi request reprint Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints - a prospective observational study
    Matthias Rostock
    Institute of Complementary Medicine, University Hospital, Zurich, Switzerland
    Gynecol Endocrinol 27:844-8. 2011
    ..As estrogen substitution is contraindicated, herbal alternatives, e.g. extracts of black cohosh are often used...
  14. doi request reprint A hypericum extract in the treatment of depressive symptoms in outpatients: an open study
    Jörg Melzer
    Dept of Internal Medicine, Institute of Complementary Medicine, University Hospital Zurich, Zurich, Switzerland
    Forsch Komplementmed 17:7-14. 2010
    ..However, as their use in daily practice may differ from that in RCTs we have conducted a study to achieve a better estimate of the range and frequency of adverse drug reactions (ADR) and the efficacy...
  15. doi request reprint Efficacy and safety of mistletoe preparations (Viscum album) for patients with cancer diseases. A systematic review
    Jörg Melzer
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
    Forsch Komplementmed 16:217-26. 2009
    ..Mistletoe is often used as a complementary approach in oncology. Despite experimental anti-tumour effects and several reviews there remains controversy about its clinical role...
  16. ncbi request reprint [Efficacy and safety of Padma 28 in peripheral arterial occlusive disease]
    Jörg Melzer
    Institut für Naturheilkunde, Departement Innere Medizin, Universitatsspital Zurich, Schweiz
    Forsch Komplementmed 13:23-7. 2006
    ..The multicompound herbal drug Padma 28 is based on a formula from Tibetan Medicine and has been used in Switzerland for over 30 years in the symptomatic treatment of circulatory disorders including intermittent claudication...
  17. doi request reprint Fixed herbal drug combination with and without butterbur (Ze 185) for the treatment of patients with somatoform disorders: randomized, placebo-controlled pharmaco-clinical trial
    Jörg Melzer
    Institute of Complementary Medicine, Department for Internal Medicine, University Hospital Zurich, Switzerland
    Phytother Res 23:1303-8. 2009
    ..This herbal preparation (Ze185) showed to be an efficacious and safe short-term treatment in patients with somatoform disorders...
  18. ncbi request reprint Evaluation of cell death caused by triterpene glycosides and phenolic substances from Cimicifuga racemosa extract in human MCF-7 breast cancer cells
    Katarina Hostanska
    Department of Internal Medicine F GEL 102, University Hospital Zurich, Switzerland
    Biol Pharm Bull 27:1970-5. 2004
    ..In addition, TTG and CAE compounds significantly contributed to its apoptotic effect, CAE being the more potent inhibitor of proliferation and apoptosis inducer...
  19. ncbi request reprint Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells
    Katarina Hostanska
    University Hospital Zurich, Department of Internal Medicine, Institute for Complementary Medicine, FGel 102, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Cancer Detect Prev 31:129-39. 2007
    ....
  20. doi request reprint Preliminary data of a HAMD-17 validated symptom scale derived from the ICD-10 to diagnose depression in outpatients
    Jörg Melzer
    Institute of Complementary Medicine, University Hospital Zurich, Switzerland
    Forsch Komplementmed 19:191-6. 2012
    ..However, physicians working in primary care are familiar with ICD-10 criteria. Therefore, the aim of the present study was to examine the feasibility of the validation of an ICD-10-derived symptom scale for depression...
  21. doi request reprint Phytodolor® in musculoskeletal disorders: re-analysis and meta-analysis
    Bernhard Uehleke
    Institute of Complementary Medicine, University Hospital Zurich
    Forsch Komplementmed 18:249-56. 2011
    ..Although already reviewed, no quantitative evaluation of efficacy and safety of the herbal combination Phytodolor® (STW1) is available...
  22. doi request reprint Suppression of interleukin (IL)-8 and human beta defensin-2 secretion in LPS-and/or IL-1β-stimulated airway epithelial A549 cells by a herbal formulation against respiratory infections (BNO 1030)
    Katarina Hostanska
    Department of Internal Medicine, Institute for Complementary Medicine, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
    J Ethnopharmacol 134:228-33. 2011
    ....
  23. doi request reprint Aspects of quality of primary care provided by physicians certified in phytotherapy in Switzerland
    Jörg Melzer
    Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
    Forsch Komplementmed 15:82-8. 2008
    ..demographic data, practice structure, process of care and outcome/ treatment satisfaction between primary care physicians certified in phytotherapy (CAM) and physicians performing conventional primary care (COM) and their patients?..
  24. ncbi request reprint Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines
    Katarina Hostanska
    Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
    Eur J Pharm Biopharm 56:121-32. 2003
    ..Cytocidal effects of HP and its cooperation with HY on tumor growth inhibition in a synergistic manner make the St John's wort an interesting option in cancer warranting further in vitro and in vivo investigation...
  25. ncbi request reprint [Does there exist one specific "view of man" in naturopathy / complementary medicine?]
    Jörg Melzer
    Institut für Naturheilkunde, Depart für Innere Medizin, Universitätspital Zürich, Ramistrasse 100, 1091 Zürich, Switzerland
    Forsch Komplementmed 13:210-9. 2006
    ..Practitioners and users of naturopathic therapies claim that one of the assumptions underlying their work is a holistic "view of man"...
  26. doi request reprint Additive antimicrobial [corrected] effects of the active components of the essential oil of Thymus vulgaris--chemotype carvacrol
    Felix Iten
    Institute of Complementary Medicine, University Hospital Zurich, Zurich, Switzerland
    Planta Med 75:1231-6. 2009
    ....
  27. ncbi request reprint [Tibetan remedies in chronic disease]
    Reinhard Saller
    Institut für Naturheilkunde, Departement Innere Medizin, Universitatsspital Zurich, Schweiz
    Forsch Komplementmed 13:VII-VIII. 2006
  28. doi request reprint Are the correct herbal claims by Hildegard von Bingen only lucky strikes? A new statistical approach
    Bernhard Uehleke
    Institute for Complementary Medicine, University Hospital Zurich, Switzerland
    Forsch Komplementmed 19:187-90. 2012
    ..So the hypothesis arises that a medieval author could have randomly hit on 'correct' claims among his many 'wrong' ones...
  29. ncbi request reprint Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro
    Katarina Hostanska
    Departmment of Internal Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    Anticancer Res 22:2853-62. 2002
    ..The results of this study suggest the effectiveness of Boswellia serrata extract with defined content of boswellic acids...
  30. ncbi request reprint [Interview with Professor Dr. Reinhard Saller, Zurich University Hospital. Willow bark extract--more than a natural alternative in antirheumatic therapy?]
    Reinhard Saller
    Praxis (Bern 1994) 94:458. 2005
  31. ncbi request reprint Integrating patient preferences in clinical trials: a pilot study of acupuncture versus midazolam for gastroscopy
    Dieter Melchart
    Department of Internal Medicine II, Centre for Complementary Medicine Research, Technische Universitat, Munich, Germany
    J Altern Complement Med 8:265-74. 2002
    ....
  32. ncbi request reprint [Willow bark extract: more than a natural alternative for the treatment of rheumatism?]
    Reinhard Saller
    Rev Med Suisse 1:971. 2005
  33. ncbi request reprint "Quality profiling" for complementary medicine: the example of a hospital for traditional Chinese medicine
    Dieter Melchart
    Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat Munchen, Munchen, Germany
    J Altern Complement Med 9:193-206. 2003
    ....
  34. doi request reprint [Concerning the individual, subjective and integrative in complementary medicine]
    Reinhard Saller
    Forsch Komplementmed 15:4-5. 2008
  35. ncbi request reprint Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study
    Reto Widrig
    Rheumatology Clinic, 9004, St Gallen, Switzerland
    Rheumatol Int 27:585-91. 2007
    ..Adverse events were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica. Our results confirm that this preparation of arnica is not inferior to ibuprofen when treating osteoarthritis of hands...
  36. ncbi request reprint [Protocol application as an understandable format and systematic elevated experiences]
    Reinhard Saller
    Forsch Komplementarmed Klass Naturheilkd 12:312-3. 2005
  37. ncbi request reprint Polysaccharides isolated from Echinacea purpurea herba cell cultures to counteract undesired effects of chemotherapy--a pilot study
    Dieter Melchart
    Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat, Kaiserstrasse 9, 80801 Munich, Germany
    Phytother Res 16:138-42. 2002
    ..The results of this pilot study suggest that EPS-EPO VIIa might be effective in reducing chemotherapy-induced leukopenia. The efficacy and safety should be investigated in further studies...