Research Topics
| Reinhard SallerSummaryAffiliation: University Hospital Country: Switzerland Publications
| Collaborators |
Detail Information
Publications
[Multimorbidity and multi-target-therapy with herbal drugs]R Saller
Institut für Naturheilkunde, Universitatsspital Zurich
Praxis (Bern 1994) 101:1637-42. 2012..However, at present there is still a great need and demand for therapy-oriented clinical research...- [Antiinflammatory herbal drugs and their therapeutic potential in tumor patients]Reinhard Saller
Institut für Naturheilkunde, Universitatsspital, Zurich, Schweiz
Forsch Komplementmed 18:203-12. 2011 - An updated systematic review with meta-analysis for the clinical evidence of silymarinReinhard Saller
Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
Forsch Komplementmed 15:9-20. 2008..The potential benefit of silymarin (special extract from the fruits of Silybum marianum) in the treatment of liver diseases remains a controversial issue... 
An updated systematic review of the pharmacology of silymarinReinhard Saller
Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
Forsch Komplementmed 14:70-80. 2007..Recent years have seen an explosion of scientific papers that deal with drugs from the fruits of milk thistle and its active substances silymarin (standardized mixture of flavonolignanes), thus justifying an updated systematic review...- Comparison of the growth-inhibitory effect of Hypericum perforatum L. extracts, differing in the concentration of phloroglucinols and flavonoids, on leukaemia cellsKatarina Hostanska
Department of Internal Medicine F NUK 104, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
J Pharm Pharmacol 55:973-80. 2003..5 microM flavonoids. The results of this study supported the hypothesis that, apart from hyperforin and flavonoids, other components of the extract could be involved in its growth-inhibitory effect that it exerts without light activation... - Apoptosis of human prostate androgen-dependent and -independent carcinoma cells induced by an isopropanolic extract of black cohosh involves degradation of cytokeratin (CK) 18Katarina Hostanska
Department of Internal Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
Anticancer Res 25:139-47. 2005..The cell growth inhibitory effect of an isopropanolic extract of black cohosh (iCR) on androgen-sensitive LNCaP and androgen-insensitive PC-3 and DU 145 prostate cancer cells was investigated... - Evaluation of cell death caused by an ethanolic extract of Serenoae repentis fructus (Prostasan) on human carcinoma cell linesKatarina Hostanska
University Hospital Zurich, Department of Internal Medicine, Institute for Complementary Medicine, Ramistrasse 100, 8091 Zurich, Switzerland
Anticancer Res 27:873-81. 2007..The lipido-sterolic extract of the fruit of Serenoa repens is one of the more widely used phytotherapeutic agents in this regard... - Inhibitory effect of an isopropanolic extract of black cohosh on the invasiveness of MDA-mB 231 human breast cancer cellsKatarina Hostanska
Department of Internal Medicine, Institute for Complementary Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
In Vivo 21:349-55. 2007..To broaden observations, the anti-invasive effects of iCR and its two major fractions triterpene glycosides (TTG) and cinnamic acid esters (CAE) were tested in highly invasive MDA-MB 231 cells... - Treating intermittent claudication with Tibetan medicine Padma 28: does it work?Jörg Melzer
Department of Internal Medicine, Complementary Medicine, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
Atherosclerosis 189:39-46. 2006..e. walking distance), probably of the same order of magnitude as other employed medications. However, larger confirmatory RCTs are desirable... - A hypericum extract in the treatment of depressive symptoms in outpatients: an open studyJörg Melzer
Dept of Internal Medicine, Institute of Complementary Medicine, University Hospital Zurich, Zurich, Switzerland
Forsch Komplementmed 17:7-14. 2010..However, as their use in daily practice may differ from that in RCTs we have conducted a study to achieve a better estimate of the range and frequency of adverse drug reactions (ADR) and the efficacy... - Efficacy and safety of mistletoe preparations (Viscum album) for patients with cancer diseases. A systematic reviewJörg Melzer
Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
Forsch Komplementmed 16:217-26. 2009..Mistletoe is often used as a complementary approach in oncology. Despite experimental anti-tumour effects and several reviews there remains controversy about its clinical role... - Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints - a prospective observational studyMatthias Rostock
Institute of Complementary Medicine, University Hospital, Zurich, Switzerland
Gynecol Endocrinol 27:844-8. 2011..As estrogen substitution is contraindicated, herbal alternatives, e.g. extracts of black cohosh are often used... - Systematic review of clinical data with BNO-101 (Sinupret) in the treatment of sinusitisJörg Melzer
Institute of Complementary Medicine, Department of Internal Medicine, University Hospital, Zurich, Switzerland
Forsch Komplementmed 13:78-87. 2006..This paper reviews the clinical evidence of BNO-101 in sinusitis... - Fixed herbal drug combination with and without butterbur (Ze 185) for the treatment of patients with somatoform disorders: randomized, placebo-controlled pharmaco-clinical trialJörg Melzer
Institute of Complementary Medicine, Department for Internal Medicine, University Hospital Zurich, Switzerland
Phytother Res 23:1303-8. 2009..This herbal preparation (Ze185) showed to be an efficacious and safe short-term treatment in patients with somatoform disorders... - Evaluation of cell death caused by triterpene glycosides and phenolic substances from Cimicifuga racemosa extract in human MCF-7 breast cancer cellsKatarina Hostanska
Department of Internal Medicine F GEL 102, University Hospital Zurich, Switzerland
Biol Pharm Bull 27:1970-5. 2004..In addition, TTG and CAE compounds significantly contributed to its apoptotic effect, CAE being the more potent inhibitor of proliferation and apoptosis inducer... - Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cellsKatarina Hostanska
University Hospital Zurich, Department of Internal Medicine, Institute for Complementary Medicine, FGel 102, Ramistrasse 100, CH 8091 Zurich, Switzerland
Cancer Detect Prev 31:129-39. 2007.... - Preliminary data of a HAMD-17 validated symptom scale derived from the ICD-10 to diagnose depression in outpatientsJörg Melzer
Institute of Complementary Medicine, University Hospital Zurich, Switzerland
Forsch Komplementmed 19:191-6. 2012..However, physicians working in primary care are familiar with ICD-10 criteria. Therefore, the aim of the present study was to examine the feasibility of the validation of an ICD-10-derived symptom scale for depression... - Phytodolor® in musculoskeletal disorders: re-analysis and meta-analysisBernhard Uehleke
Institute of Complementary Medicine, University Hospital Zurich
Forsch Komplementmed 18:249-56. 2011..Although already reviewed, no quantitative evaluation of efficacy and safety of the herbal combination Phytodolor® (STW1) is available... - Suppression of interleukin (IL)-8 and human beta defensin-2 secretion in LPS-and/or IL-1β-stimulated airway epithelial A549 cells by a herbal formulation against respiratory infections (BNO 1030)Katarina Hostanska
Department of Internal Medicine, Institute for Complementary Medicine, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
J Ethnopharmacol 134:228-33. 2011.... - Aspects of quality of primary care provided by physicians certified in phytotherapy in SwitzerlandJörg Melzer
Institute of Complementary Medicine, Department of Internal Medicine, University Hospital Zurich, Switzerland
Forsch Komplementmed 15:82-8. 2008..demographic data, practice structure, process of care and outcome/ treatment satisfaction between primary care physicians certified in phytotherapy (CAM) and physicians performing conventional primary care (COM) and their patients?.. - [Efficacy and safety of Padma 28 in peripheral arterial occlusive disease]Jörg Melzer
Institut für Naturheilkunde, Departement Innere Medizin, Universitatsspital Zurich, Schweiz
Forsch Komplementmed 13:23-7. 2006..The multicompound herbal drug Padma 28 is based on a formula from Tibetan Medicine and has been used in Switzerland for over 30 years in the symptomatic treatment of circulatory disorders including intermittent claudication... - [Tibetan remedies in chronic disease]Reinhard Saller
, Departement Innere Medizin, , Schweiz
Forsch Komplementmed 13:VII-VIII. 2006 - Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell linesKatarina Hostanska
Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
Eur J Pharm Biopharm 56:121-32. 2003..Cytocidal effects of HP and its cooperation with HY on tumor growth inhibition in a synergistic manner make the St John's wort an interesting option in cancer warranting further in vitro and in vivo investigation... 
A homeopathic remedy from arnica, marigold, St. John's wort and comfrey accelerates in vitro wound scratch closure of NIH 3T3 fibroblastsKatarina Hostanska
Institute for Complementary Medicine, University Hospital Zurich, Raemistrasse 100, Zurich, 8091, Switzerland
BMC Complement Altern Med 12:100. 2012..abstract:..- [Does there exist one specific "view of man" in naturopathy / complementary medicine?]Jörg Melzer
Institut für Naturheilkunde, Depart für Innere Medizin, Universitätspital Zürich, Ramistrasse 100, 1091 Zürich, Switzerland
Forsch Komplementmed 13:210-9. 2006..Practitioners and users of naturopathic therapies claim that one of the assumptions underlying their work is a holistic "view of man"... - Additive antimicrobial [corrected] effects of the active components of the essential oil of Thymus vulgaris--chemotype carvacrolFelix Iten
Institute of Complementary Medicine, University Hospital Zurich, Zurich, Switzerland
Planta Med 75:1231-6. 2009.... - Are the correct herbal claims by Hildegard von Bingen only lucky strikes? A new statistical approachBernhard Uehleke
Institute for Complementary Medicine, University Hospital Zurich, Switzerland
Forsch Komplementmed 19:187-90. 2012..So the hypothesis arises that a medieval author could have randomly hit on 'correct' claims among his many 'wrong' ones... - Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitroKatarina Hostanska
Departmment of Internal Medicine, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
Anticancer Res 22:2853-62. 2002..The results of this study suggest the effectiveness of Boswellia serrata extract with defined content of boswellic acids... - [Interview with Professor Dr. Reinhard Saller, Zurich University Hospital. Willow bark extract--more than a natural alternative in antirheumatic therapy?]Reinhard Saller
Praxis (Bern 1994) 94:458. 2005 - [Concerning the individual, subjective and integrative in complementary medicine]Reinhard Saller
Forsch Komplementmed 15:4-5. 2008 - Integrating patient preferences in clinical trials: a pilot study of acupuncture versus midazolam for gastroscopyDieter Melchart
Department of Internal Medicine II, Centre for Complementary Medicine Research, , Munich, Germany
J Altern Complement Med 8:265-74. 2002..The partially randomized patient preference design is recommended for use in future trials of acupuncture for gastroscopy. Such trials should be performed in an outpatient setting... - "Quality profiling" for complementary medicine: the example of a hospital for traditional Chinese medicineDieter Melchart
Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat Munchen, Munchen, Germany
J Altern Complement Med 9:193-206. 2003.... - Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind studyReto Widrig
Rheumatology Clinic, 9004, St Gallen, Switzerland
Rheumatol Int 27:585-91. 2007..Adverse events were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica. Our results confirm that this preparation of arnica is not inferior to ibuprofen when treating osteoarthritis of hands... - [Protocol application as an understandable format and systematic elevated experiences]Reinhard Saller
Forsch Komplementarmed Klass Naturheilkd 12:312-3. 2005 - [Willow bark extract: more than a natural alternative for the treatment of rheumatism?]Reinhard Saller
Rev Med Suisse 1:971. 2005 - Polysaccharides isolated from Echinacea purpurea herba cell cultures to counteract undesired effects of chemotherapy--a pilot studyDieter Melchart
Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat, Kaiserstrasse 9, 80801 Munich, Germany
Phytother Res 16:138-42. 2002..The results of this pilot study suggest that EPS-EPO VIIa might be effective in reducing chemotherapy-induced leukopenia. The efficacy and safety should be investigated in further studies...