Naomi Sakai

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint Anionic fullerenes, calixarenes, coronenes, and pyrenes as activators of oligo/polyarginines in model membranes and live cells
    Florent Perret
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland, Institute for Chemical Research, Kyoto University and PRESTO, JST, Kyoto, Japan
    J Am Chem Soc 127:1114-5. 2005
  2. ncbi request reprint Dendritic folate rosettes as ion channels in lipid bilayers
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 128:2218-9. 2006
  3. ncbi request reprint Programmed assembly of rigid-rod beta-barrel pores: thermal inversion of chirality
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chirality 16:S28-35. 2004
  4. ncbi request reprint Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, 30, Quai Ernest Ansermet, 1211 Geneva 4, Switzerland
    Chembiochem 6:114-22. 2005
  5. ncbi request reprint Anion-mediated transfer of polyarginine across liquid and bilayer membranes
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 125:14348-56. 2003
  6. ncbi request reprint G-quartet self-assembly under osmotic pressure: remote control by vesicle shrinking rather than stress
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chirality 15:766-71. 2003
  7. ncbi request reprint Synthetic catalytic pores
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, CH 1211 Geneva, Switzerland
    J Am Chem Soc 125:7776-7. 2003
  8. ncbi request reprint Voltage-dependent formation of anion channels by synthetic rigid-rod push-pull beta-barrels
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, 1211 Geneva 4, Switzerland
    Chemistry 9:223-32. 2003
  9. doi request reprint Ultrafast photoinduced charge separation in naphthalene diimide based multichromophoric systems in liquid solutions and in a lipid membrane
    Natalie Banerji
    Department of Physical Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH 1211 Geneva 4, Switzerland
    J Phys Chem B 112:8912-22. 2008
  10. ncbi request reprint Thermodynamic and kinetic stability of synthetic multifunctional rigid-rod beta-barrel pores: evidence for supramolecular catalysis
    Svetlana Litvinchuk
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 126:10067-75. 2004

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Anionic fullerenes, calixarenes, coronenes, and pyrenes as activators of oligo/polyarginines in model membranes and live cells
    Florent Perret
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland, Institute for Chemical Research, Kyoto University and PRESTO, JST, Kyoto, Japan
    J Am Chem Soc 127:1114-5. 2005
    ..Applied to HeLa cells, pyrenebutyrate is shown to significantly increase the uptake of a fluorescently labeled octaarginine in a concentration-dependent manner...
  2. ncbi request reprint Dendritic folate rosettes as ion channels in lipid bilayers
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 128:2218-9. 2006
    ..The found ion channels are small, quite homogeneous, long-lived, ohmic, cation selective (Eisenman I), and blockable by the permeant cation...
  3. ncbi request reprint Programmed assembly of rigid-rod beta-barrel pores: thermal inversion of chirality
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chirality 16:S28-35. 2004
    ..Qualitative thermal inversion of supramolecular chirality during programmed assembly was detected continuously. Inversion of supramolecular chirality occurred with decreasing solvent polarity as well...
  4. ncbi request reprint Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, 30, Quai Ernest Ansermet, 1211 Geneva 4, Switzerland
    Chembiochem 6:114-22. 2005
    ....
  5. ncbi request reprint Anion-mediated transfer of polyarginine across liquid and bilayer membranes
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 125:14348-56. 2003
    ..The infinite variability and dynamic nature of available regulatory anion cocktails may contribute to the elusive character of guanidinium-rich oligo/polymer function in biomembranes...
  6. ncbi request reprint G-quartet self-assembly under osmotic pressure: remote control by vesicle shrinking rather than stress
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chirality 15:766-71. 2003
    ....
  7. ncbi request reprint Synthetic catalytic pores
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, CH 1211 Geneva, Switzerland
    J Am Chem Soc 125:7776-7. 2003
    ..3) is discussed as one possible explanation of this global reduction of catalyst saturation. Control experiments show, inter alia, that similarly strong changes do not occur with opposing membrane potentials...
  8. ncbi request reprint Voltage-dependent formation of anion channels by synthetic rigid-rod push-pull beta-barrels
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, 1211 Geneva 4, Switzerland
    Chemistry 9:223-32. 2003
    ..Fluorescence depth quenching and circular dichroism studies confirm the effect of membrane potentials in promotion of the partitioning of 5 (but not 6) into the bilayers, identifying partitioning as the voltage-dependent step...
  9. doi request reprint Ultrafast photoinduced charge separation in naphthalene diimide based multichromophoric systems in liquid solutions and in a lipid membrane
    Natalie Banerji
    Department of Physical Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH 1211 Geneva 4, Switzerland
    J Phys Chem B 112:8912-22. 2008
    ..A better spatial separation of the charges in the red system stemming from the localization of the hole on the p-octiphenyl scaffold could additionally contribute to the slowing down of charge recombination...
  10. ncbi request reprint Thermodynamic and kinetic stability of synthetic multifunctional rigid-rod beta-barrel pores: evidence for supramolecular catalysis
    Svetlana Litvinchuk
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 126:10067-75. 2004
    ..The first molecular mechanics modeling (MacroModel, MMFF94) of multifunctional rigid-rod beta-barrel pore hosts 1 with internal 1,3,6-pyrenetrisulfonate guests is reported...
  11. ncbi request reprint Photoproduction of proton gradients with pi-stacked fluorophore scaffolds in lipid bilayers
    Sheshanath Bhosale
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Science 313:84-6. 2006
    ..Ligand intercalation transformed the photoactive scaffolds into ion channels...
  12. doi request reprint Optoelectronically mismatched oligophenylethynyl-naphthalenediimide SHJ architectures
    Santanu Maity
    Department of Organic, University of Geneva, Geneva, Switzerland
    Org Biomol Chem 8:1052-7. 2010
    ..NDI excitation is not followed by the complementary hole transfer to the OPE rod. Scaffolds with higher HOMOs will be needed to integrate blue NDIs into SHJ photosystems...
  13. ncbi request reprint Counterion-activated polyions as soft sensing systems in lipid bilayer membranes: from cell-penetrating peptides to DNA
    Toshihide Takeuchi
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Faraday Discuss 143:187-203; discussion 265-75. 2009
    ....
  14. ncbi request reprint Synthetic multifunctional pores that open and close in response to chemical stimulation
    Virginie Gorteau
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Bioorg Med Chem 13:5171-80. 2005
    ..Refined molecular models show good agreement with pore design and experimental facts with regard to function...
  15. ncbi request reprint Ligand-gated synthetic ion channels
    Pinaki Talukdar
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chemistry 11:6525-32. 2005
    ..Control experiments demonstrate that minor structural changes leading to internal decrowding suffice to cleanly annihilate chiral self-organization and function...
  16. ncbi request reprint Use of the exciton chirality method in the investigation of ligand-gated synthetic ion channels
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chirality 18:91-4. 2006
    ....
  17. doi request reprint Substrate-initiated synthesis of cell-penetrating poly(disulfide)s
    Eun Kyoung Bang
    School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 135:2088-91. 2013
    ..The same process is further characterized by gel-permeation chromatography and fluorescence resonance energy transfer...
  18. doi request reprint Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesicles
    David Alonso Doval
    School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland
    Org Biomol Chem 10:6087-93. 2012
    ..These results confirm the potential of dynamic fluorescent amphiphiles to selectively label extra- and intracellular membrane domains and visualize biological function...
  19. ncbi request reprint Ion channels and pores, made from scratch
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Mol Biosyst 3:658-66. 2007
    ..We elaborate on the structural diversity well beyond the biological limitations that becomes accessible with synthetic ion channels and pores, and on the importance of advanced nanoarchitecture to create significant function...
  20. doi request reprint Excited-state dynamics of hybrid multichromophoric systems: toward an excitation wavelength control of the charge separation pathways
    Natalie Banerji
    Department of Physical Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH 1211 Geneva 4, Switzerland
    J Phys Chem A 113:8202-12. 2009
    ..Because of this, the relative energies of the two charge-separated states (hole on the OPE or an NDI) are inverted...
  21. ncbi request reprint Arginine magic with new counterions up the sleeve
    Masamichi Nishihara
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Org Biomol Chem 3:1659-69. 2005
    ....
  22. ncbi request reprint Outer surface modification of synthetic multifunctional pores
    Pinaki Talukdar
    Department of Organic Chemistry, University of Geneva, CH 1211 Geneva 4, Switzerland
    Bioorg Med Chem 12:1325-36. 2004
    ..The relation between the stability of supramolecular (pre)pores and dependence of activity on monomer concentration is discussed in a more general context...
  23. ncbi request reprint Rapid and mild synthesis of functionalized naphthalenediimides
    Ravuri S K Kishore
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Org Chem 73:738-40. 2008
    ..Here, we report rapid access to blue, red, and yellow NDIs under mild conditions with tolerance toward the additional presence of pertinent functional groups...
  24. doi request reprint Transmembrane anion transport mediated by halogen-bond donors
    Andreas Vargas Jentzsch
    Department of Organic Chemistry, University of Geneva, Geneva CH 1211, Switzerland
    Nat Commun 3:905. 2012
    ..Contrary to the destructive action of small-molecule detergents, transport with halogen bonds is leakage-free, cooperative, non-ohmic and highly selective, with anion/cation permeability ratios <37...
  25. ncbi request reprint Engineering antiparallel charge-transfer cascades into supramolecular n/p-heterojunction photosystems: toward directional self-sorting on surfaces
    Marco Lista
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Faraday Discuss 155:63-77; discussion 103-14. 2012
    ..However, the reduction of efforts devoted to covalent organic synthesis will have to be compensated by the development of strategic concepts on the supramolecular level to tackle basic questions such as self-sorting on surfaces...
  26. doi request reprint Naphthalene- and perylenediimides with hydroquinones, catechols, boronic esters and imines in the core
    Andrea Fin
    School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland
    Org Biomol Chem 9:8246-52. 2011
    ..We conclude that the panchromatic hypersensitivity toward the environment of the new cNDIs is ideal for pattern generation in differential sensing arrays...
  27. ncbi request reprint Complementary characteristics of homologous p-octiphenyl beta-barrels with ion channel and esterase activity
    Abhigyan Som
    Department of Organic Chemistry, University of Geneva, CH 1211 Geneva 4, Switzerland
    Bioorg Med Chem 11:1363-9. 2003
    ....
  28. ncbi request reprint Synthetic multifunctional pores with external and internal active sites for ligand gating and noncompetitive blockage
    Virginie Gorteau
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 126:13592-3. 2004
    ..Practical usefulness of ligand-gated synthetic multifunctional pores is exemplified with the continuous detection of chemical processes...
  29. doi request reprint Anion-π catalysis
    Yingjie Zhao
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 136:2101-11. 2014
    ..e., the existence of anion-π catalysis. Preliminary results on the general significance of anion-π catalysis beyond the Kemp elimination are briefly discussed. ..
  30. doi request reprint Self-organizing surface-initiated polymerization, templated self-sorting and templated stack exchange: synthetic methods to build complex systems
    Marco Lista
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Org Biomol Chem 11:1754-65. 2013
    ..Compatibility of this robust method with the creation of double-channel architectures with antiparallel two-component gradients has been demonstrated...
  31. doi request reprint Catalysis with anion-π interactions
    Yingjie Zhao
    Department of Organic Chemistry, University of Geneva, Geneva Switzerland http www unige ch sciences chiorg matile
    Angew Chem Int Ed Engl 52:9940-3. 2013
    ..The conclusion is inevitable: Increasing stabilization of an anionic transition state with increasing π-acidity of the catalyst is observed; thus, anion-π interactions can contribute to catalysis. ..
  32. doi request reprint Directional stack exchange along oriented oligothiophene stacks
    Jetsuda Areephong
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chem Commun (Camb) 48:10618-20. 2012
    ..Successful addition of co-axial π-acidic stacks by templated hydrazone exchange provides general access to multicomponent architectures of unique complexity...
  33. doi request reprint Synthesis of an enlarged library of dynamic DNA activators with oxime, disulfide and hydrazone bridges
    Javier Montenegro
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chemistry 18:10436-43. 2012
    ..Moreover, oximes, contrary to hydrazones, remain active under acidic conditions. Linear elongation of dendritic head-groups seems to cause increasing detergent effects and should therefore be avoided...
  34. doi request reprint Conceptually new entries into cells
    Javier Montenegro
    School of Chemistry and Biochemistry, University of Geneva, CH 1211 Geneva, Switzerland
    Chimia (Aarau) 65:853-8. 2011
    ..Emphasis is on the use of dynamic covalent chemistry for counterion activation, slow release of polyions and fluorescent probes, and the generation of activator libraries and polyions that grow and shrink...
  35. ncbi request reprint Synthetic functional pi-stack architecture in lipid bilayers
    Sheshanath Bhosale
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Org Biomol Chem 4:3031-9. 2006
    ....
  36. ncbi request reprint Self-organizing surface-initiated polymerization: facile access to complex functional systems
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva 1211, Switzerland
    J Am Chem Soc 133:15224-7. 2011
    ..The activity of SOSIP architectures is clearly better than that of disordered controls...
  37. doi request reprint Artificial beta-barrels
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Acc Chem Res 41:1354-65. 2008
    ..Further refinements include the introduction of asymmetric staves for voltage gating and anchoring of the pore at the membrane-water interface...
  38. ncbi request reprint Rigid-rod molecules in biomembrane models: from hydrogen-bonded chains to synthetic multifunctional pores
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Acc Chem Res 38:79-87. 2005
    ..Recent molecular mechanics simulations are presented as a valuable approach to insights on the elusive suprastructures of multifunctional pores made from rigid rods...
  39. doi request reprint Ordered and oriented supramolecular n/p-heterojunction surface architectures: completion of the primary color collection
    Ravuri S K Kishore
    Department of Organic, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 131:11106-16. 2009
    ....
  40. ncbi request reprint Cellular uptake of substrate-initiated cell-penetrating poly(disulfide)s
    Giulio Gasparini
    School of Chemistry and Biochemistry, National Centre of Competence in Research NCCR Chemical Biology, University of Geneva, Geneva 1211, Switzerland
    J Am Chem Soc 136:6069-74. 2014
    ..Supported by experimental evidence, a unique combination of the counterion-mediated translocation of CPPs with the underexplored, thiol-mediated covalent translocation is considered to account for this decisive difference. ..
  41. doi request reprint A quantitative model for the transcription of 2D patterns into functional 3D architectures
    Edvinas Orentas
    Department of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland
    Nat Chem 4:746-50. 2012
    ..The functional relevance of surface-templated self-sorting and meaningful dependences of templation efficiencies on structural modifications are demonstrated...
  42. pmc A rivet model for channel formation by aerolysin-like pore-forming toxins
    Ioan Iacovache
    Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland
    EMBO J 25:457-66. 2006
    ..This rivet-like conformation was modeled and sequence alignments suggest that such channel riveting may operate for many other pore-forming toxins...
  43. ncbi request reprint Polarized vesicles in molecular recognition and catalysis
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH 1211 Geneva
    Chem Biodivers 1:28-43. 2004
    ..Examples for the recognition of and self-assembly, molecular recognition, and catalysis in polarized vesicles are discussed with emphasis on 'remote control' by dipole-potential interactions and electrostatic steering...
  44. ncbi request reprint Comparison of lipoic and asparagusic acid for surface-initiated disulfide-exchange polymerization
    Alessio Carmine
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chemistry 19:11558-63. 2013
    ....
  45. doi request reprint Toward oriented surface architectures with three coaxial charge-transporting pathways
    Giuseppe Sforazzini
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 135:12082-90. 2013
    ..The reported approach will allow us to systematically unravel the ultrafast photophysics of molecular dyads and triads in surface architectures, and might become useful to develop conceptually innovative optoelectronic devices. ..
  46. ncbi request reprint Supramolecular n/p-Heterojunction Photosystems with Antiparallel Redox Gradients in Electron- and Hole-Transporting Pathways
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, 1211 Geneva 4, Switzerland
    J Am Chem Soc 132:6923-5. 2010
    ..The presence of both gradients is shown to be essential for achieving photoinduced charge separation over very long distances...
  47. ncbi request reprint Sensing, threading, orienting, and cutting polymers with rigid-rod pores
    Stefan Matile
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Recept Signal Transduct Res 26:461-72. 2006
    ..The spotlight is on recent breakthroughs to image the longtime elusive pore-polymer host-guest complexes as single giant pseudorotaxanes...
  48. doi request reprint Supramolecular n/p-heterojunction photosystems with oriented multicolored antiparallel redox gradients (OMARG-SHJs)
    Rajesh Bhosale
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chem Soc Rev 39:138-49. 2010
    ..This conceptually innovative twist added to a timely topic should appeal to the synthetic organic, supramolecular, biological, physical, analytical and materials chemist as well as to the expert in energy and environmental sciences...
  49. ncbi request reprint Ion-gated synthetic photosystems
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, CH 1211 Geneva, Switzerland
    J Am Chem Soc 136:5575-8. 2014
    ..Turned off by inhibited anion mobility, that is, proton hopping, hole/proton antiport is identified to account for long-distance charge transport in ion-gated photosystems. ..
  50. ncbi request reprint Lateral self-sorting on surfaces: a practical approach to double-channel photosystems
    Marco Lista
    Department of Organic Chemistry, University of Geneva, Geneva 1211, Switzerland
    J Am Chem Soc 133:15228-31. 2011
    ..Experimental support for self-repair during co-SOSIP is reported. Initiators on the surface are shown to serve as templates for the self-sorting into multichannel architectures of freely variable composition...
  51. ncbi request reprint Interface engineering of synthetic pores: towards hypersensitive biosensors
    Federico Mora
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chemistry 14:1947-53. 2008
    ..The scope and limitations of this approach are exemplified with pertinent analyte pairs that are essential for the sensing of sucrose, lactose, acetate, and glutamate with synthetic pores in samples from the supermarket...
  52. ncbi request reprint Recognition of polarized lipid bilayers by p-oligophenyl ion channels: from push-pull rods to push-pull barrels
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, CH 1211 Geneva, Switzerland
    J Am Chem Soc 124:1184-5. 2002
    ..Nonlinear concentration dependence of activity at -180 mV indicates parallel self-assembly of push-pull rod 1 into a tetrameric barrel-stave supramolecule...
  53. ncbi request reprint Zipper and layer-by-layer assemblies of artificial photosystems analyzed by combining optical and piezoelectric surface techniques
    Mariya Porus
    Department of Inorganic, Analytical, and Applied Chemistry, University of Geneva, Geneva, Switzerland
    Langmuir 27:7213-21. 2011
    ..These features are in excellent agreement with the better photophysical performance of the OPE-NDI assemblies when compared to the POP-NDI films...
  54. ncbi request reprint Enolate chemistry with anion-π interactions
    Yingjie Zhao
    Department of Organic Chemistry, University of Geneva, Geneva CH 1211, Switzerland
    Nat Commun 5:3911. 2014
    ..These findings are significant because enolate chemistry is central in chemistry and biology, and they will stimulate the use of anion-π interactions in catalysis in the broadest sense...
  55. ncbi request reprint A collection of fullerenes for synthetic access toward oriented charge-transfer cascades in triple-channel photosystems
    Altan Bolag
    Department of Organic Chemistry, University of Geneva, Geneva Switzerland http www unige ch sciences chiorg matile
    Angew Chem Int Ed Engl 53:4890-5. 2014
    ..For the creation of this collection, modern fullerene chemistry-methanofullerenes and 1,4-diarylfullerenes-is combined with classical Nierengarten-Diederich-Bingel approaches. ..
  56. doi request reprint Stereoselective self-sorting on surfaces: transcription of chiral information
    Edvinas Orentas
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Chirality 25:107-13. 2013
    ....
  57. doi request reprint Oligothiophene amphiphiles as planarizable and polarizable fluorescent membrane probes
    Andrea Fin
    Department of Organic Chemistry, University of Geneva, Geneva Switzerland http www unige ch sciences chiorg matile
    Angew Chem Int Ed Engl 51:12736-9. 2012
    ....
  58. ncbi request reprint Recent progress with functional biosupramolecular systems
    David Alonso Doval
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Langmuir 27:9696-705. 2011
    ..The functional diversity accessible with biosupramolecular systems is highlighted, as is the critical importance of cross-fertilization at intertopical convergence zones...
  59. doi request reprint Lysobisphosphatidic acid controls endosomal cholesterol levels
    Julien Chevallier
    Departments of Biochemistry, University of Geneva, 30 quai E Ansermet, 1211 Geneva 4, Switzerland
    J Biol Chem 283:27871-80. 2008
    ..We conclude that LBPA controls the cholesterol capacity of endosomes...
  60. ncbi request reprint Binding of organic anions by synthetic supramolecular metallopores with internal Mg2+-aspartate complexes
    Gopal Das
    Department of Organic Chemistry University of Geneva 1211 Geneva 4, Switzerland
    Chembiochem 3:1089-96. 2002
    ..The negligible flippase activity measurable for Mg(2+)-free pores indicates that transmembrane p-octiphenyl beta barrels do not disturb the lipid bilayer suprastructure, in other words, they form barrel-stave rather than toroidal pores...
  61. ncbi request reprint Direct and rapid cytosolic delivery using cell-penetrating peptides mediated by pyrenebutyrate
    Toshihide Takeuchi
    ACS Chem Biol 1:299-303. 2006
    ..Thus, coupling arginine-rich peptides with this hydrophobic anion dramatically improved their ability to translocate cellular membranes, suggesting the great impact of this approach on exploring and controlling cell function...
  62. doi request reprint Synthetic ion channels
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Langmuir 29:9031-40. 2013
    ..The perspectives outline promising directions and major challenges waiting to be addressed. ..
  63. pmc Multistep organic synthesis of modular photosystems
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    Beilstein J Org Chem 8:897-904. 2012
    ....
  64. ncbi request reprint Stack exchange strategies for the synthesis of covalent double-channel photosystems by self-organizing surface-initiated polymerization
    Naomi Sakai
    Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
    J Am Chem Soc 133:18542-5. 2011
    ..With appropriate templation from the surface, post-SOSIP stack exchange is nearly quantitative...
  65. ncbi request reprint Comparison of larvicidal, adulticidal and acaricidal activity of two geometrical butylidenephthalide isomers
    Toshihiko Tsukamoto
    Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Higashiosaka, Osaka, Japan
    Biol Pharm Bull 29:592-4. 2006
    ..Insecticidal activity of both (E)- and (Z)-butylidenephthalide toward adults of C. felis was not detected even at the maximum concentration of 200 microg/cm2...