Christian Ruiz

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, Basel, Switzerland
    PLoS ONE 7:e43265. 2012
  2. doi request reprint Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, Basel, Switzerland
    J Pathol 223:543-52. 2011
  3. doi request reprint Estrogen receptor β expression and androgen receptor phosphorylation correlate with a poor clinical outcome in hormone-naive prostate cancer and are elevated in castration-resistant disease
    Tobias Zellweger
    Department of Urology, St Claraspital, Basel, Switzerland
    Endocr Relat Cancer 20:403-13. 2013
  4. doi request reprint Klf4 transcription factor is expressed in the cytoplasm of prostate cancer cells
    Clémentine Le Magnen
    Institute for Surgical Research and Hospital Management, Department of Biomedicine, Basel University Hospital, Basel, Switzerland
    Eur J Cancer 49:955-63. 2013
  5. doi request reprint High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, University of Basel, Basel, Switzerland
    Prostate 72:1678-87. 2012
  6. ncbi request reprint VEGFA gene locus analysis across 80 human tumour types reveals gene amplification in several neoplastic entities
    Mariacarla Andreozzi
    Molecular Pathology Unit, Institute of Pathology, University Hospital of Basel, Schonbeinstrasse 40, 4003, Basel, Switzerland
    Angiogenesis 17:519-27. 2014
  7. pmc Role of KCNMA1 in breast cancer
    Martin Oeggerli
    Institute of Pathology, University of Basel, Basel, Switzerland
    PLoS ONE 7:e41664. 2012
  8. pmc Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients
    Luca Quagliata
    Institute of Pathology, Molecular Pathology Division, University Hospital of Basel, Basel, Switzerland
    Hepatology 59:911-23. 2014
  9. doi request reprint VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients
    Tatjana Vlajnic
    Institute of Pathology, University Hospital Basel, Basel, Switzerland
    Mod Pathol 24:1404-12. 2011
  10. pmc Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors
    Florence Brellier
    Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, Basel, Switzerland
    BMC Clin Pathol 12:14. 2012

Collaborators

Detail Information

Publications11

  1. pmc Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, Basel, Switzerland
    PLoS ONE 7:e43265. 2012
    ..Our results further suggest that Ano1 facilitates regulation of the cell volume and causes cell migration, which both can contribute to metastatic progression in HNSCC...
  2. doi request reprint Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, Basel, Switzerland
    J Pathol 223:543-52. 2011
    ..0001). Our data suggest that vinculin is a major driving gene of the 10q22 amplification in prostate cancer and that vinculin overexpression might contribute to prostate cancer progression by enhancing tumour cell proliferation...
  3. doi request reprint Estrogen receptor β expression and androgen receptor phosphorylation correlate with a poor clinical outcome in hormone-naive prostate cancer and are elevated in castration-resistant disease
    Tobias Zellweger
    Department of Urology, St Claraspital, Basel, Switzerland
    Endocr Relat Cancer 20:403-13. 2013
    ..005). Our results strongly suggest a major role for pAR(210) and ERβ in HN PC. The expression of these markers might be directly involved in CR tumor growth...
  4. doi request reprint Klf4 transcription factor is expressed in the cytoplasm of prostate cancer cells
    Clémentine Le Magnen
    Institute for Surgical Research and Hospital Management, Department of Biomedicine, Basel University Hospital, Basel, Switzerland
    Eur J Cancer 49:955-63. 2013
    ..Here we comparatively addressed the expression of genes encoding putative stemness regulators including c-Myc, Klf4, Nanog, Oct4A and Sox2 genes in benign prostatic hyperplasia (BPH) and prostate cancer (PCA)...
  5. doi request reprint High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, University of Basel, Basel, Switzerland
    Prostate 72:1678-87. 2012
    ..Consequently, we analyzed the role of NRBP1 expression in prostate cancer cell lines and its expression on prostate cancer tissue microarrays (TMA)...
  6. ncbi request reprint VEGFA gene locus analysis across 80 human tumour types reveals gene amplification in several neoplastic entities
    Mariacarla Andreozzi
    Molecular Pathology Unit, Institute of Pathology, University Hospital of Basel, Schonbeinstrasse 40, 4003, Basel, Switzerland
    Angiogenesis 17:519-27. 2014
    ..e. HER2 and trastuzumab). However the impact of VEGFA gene amplification has been only recently assessed for some cancer types such as osteosarcoma, colorectal, breast and liver cancer...
  7. pmc Role of KCNMA1 in breast cancer
    Martin Oeggerli
    Institute of Pathology, University of Basel, Basel, Switzerland
    PLoS ONE 7:e41664. 2012
    ..Our findings revealed that enhanced expression of KCNMA1 correlates with and contributes to high proliferation rate and malignancy of breast cancer...
  8. pmc Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients
    Luca Quagliata
    Institute of Pathology, Molecular Pathology Division, University Hospital of Basel, Basel, Switzerland
    Hepatology 59:911-23. 2014
    ..In addition, taking advantage of gain and loss of function experiments in liver cancer-derived cell lines (HuH-6 and HuH-7), we uncover a novel bidirectional regulatory loop between HOTTIP/HOXA13...
  9. doi request reprint VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients
    Tatjana Vlajnic
    Institute of Pathology, University Hospital Basel, Basel, Switzerland
    Mod Pathol 24:1404-12. 2011
    ..Further studies are needed to elucidate the potential role of amplification as a prognostic or predictive biomarker in both metastatic and nonmetastatic patients...
  10. pmc Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors
    Florence Brellier
    Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, Basel, Switzerland
    BMC Clin Pathol 12:14. 2012
    ..abstract:..
  11. doi request reprint Application of personalized medicine to solid tumors: opportunities and challenges
    Christian Ruiz
    Institute for Pathology, University Hospital Basel, Switzerland
    Swiss Med Wkly 142:w13587. 2012
    ..Discussion of the use and development of the various technologies will help us to understand the opportunities and challenges that arise when novel technologies are implemented...