Research Topics
| Michel F RossierSummaryAffiliation: University Hospital Country: Switzerland Publications
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Detail Information
Publications
T channels and steroid biosynthesis: in search of a link with mitochondriaMichel F Rossier
Division of Endocrinology, Diabetology and Nutrition, Department of Internal Medicine, University Hospital, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
Cell Calcium 40:155-64. 2006..Both functional and structural evidences supporting this model of calcium transport within steroidogenic glomerulosa cells are reviewed in the present article...
Contribution of mineralocorticoid and glucocorticoid receptors to the chronotropic and hypertrophic actions of aldosterone in neonatal rat ventricular myocytesMichel F Rossier
Service of Endocrinology and Diabetology, University Hospital of Geneva, 4 rue Gabrielle Perret Gentil, CH 1211 Geneva 14, Switzerland
Endocrinology 151:2777-87. 2010....
Corticosteroids and redox potential modulate spontaneous contractions in isolated rat ventricular cardiomyocytesMichel F Rossier
Department of Internal Medicine, Division of Endocrinology and Diabetology, University Hospital of Geneva, Geneva, Switzerland
Hypertension 52:721-8. 2008..This phenomenon is believed to be because of cell electric remodeling and could contribute in vivo to the deleterious consequence of inappropriate receptor activation, leading to increased susceptibility of patients to arrhythmias...
Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytesNathalie Lalevee
Division of Endocrinology and Diabetology, Department of Internal Medicine, University Hospital, CH 1211 Geneva 14, Switzerland
Cardiovasc Res 67:216-24. 2005..This study was designed to investigate the effect of aldosterone on calcium channel expression and cardiomyocyte contraction frequency...
Hint2 is expressed in the mitochondria of H295R cells and is involved in steroidogenesisSebastien Lenglet
Service of Endocrinology and Diabetology, University Hospital of Geneva, Geneva, Switzerland
Endocrinology 149:5461-9. 2008....
Intracellular transport of calcium from plasma membrane to mitochondria in adrenal H295R cells: implication for steroidogenesisNathalie Lalevee
Division of Endocrinology and Diabetology, Department of Internal Medicine, University Hospital, CH 1211 Geneva 14, Switzerland
Endocrinology 144:4575-85. 2003..The response to potassium is proposed to be dependent on the endoplasmic reticulum-mediated transfer of calcium entering through plasma membrane calcium channels to the mitochondria...
Antiapolipoprotein A-1 IgG chronotropic effects require nongenomic action of aldosterone on L-type calcium channelsMichel F Rossier
Service of Endocrinology and Diabetology, Department of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland
Endocrinology 153:1269-78. 2012..In conclusion, our results indicate that, on NRVC, the aldosterone-dependent chronotropic effects of antiapoA-1 IgG involve the nongenomic activation of L-type calcium channels...
DHEA prevents mineralo- and glucocorticoid receptor-induced chronotropic and hypertrophic actions in isolated rat cardiomyocytesTiphaine Mannic
Service of Endocrinology, Diabetology, and Nutrition, University Hospital of Geneva, 4 rue Gabrielle Perret Gentil, CH 1211 Geneva 14, Switzerland
Endocrinology 154:1271-81. 2013..On the whole, these results suggest new mechanisms for a putative cardioprotective role of DHEA in corticosteroid-associated heart diseases...
Cortisol responses to combined dexamethasone/CRH test in outpatients with a major depressive episodeNicola Gervasoni
Adult Psychiatric Service, Department of Psychiatry, Geneva University Hospital, 16 18 bd Saint Georges, 1205 Geneva, Switzerland
J Psychiatr Res 38:553-7. 2004..In future studies, it could be interesting to use this test more specifically by dividing ambulatory patients into subgroups according to their past depressive history. It could also be interesting to measure the ACTH level...
CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosisNicolas Vuilleumier
Central Clinical Chemistry Laboratory, Department of Clinical Pathology, Geneva University Hospital, 24 Micheli du Crest, 1211, Geneva 14, Switzerland
Eur J Clin Pharmacol 62:423-9. 2006....
Anti-apolipoprotein A-1 IgG as an independent cardiovascular prognostic marker affecting basal heart rate in myocardial infarctionNicolas Vuilleumier
Service of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, Geneva 14, Switzerland
Eur Heart J 31:815-23. 2010..Anti-apoA-1 IgG have been reported in MI without autoimmune disease, but their clinical significance remains undetermined...
Aldosterone regulation of T-type calcium channelsMichel F Rossier
Division of Endocrinology and Diabetology, University Hospital of Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
J Steroid Biochem Mol Biol 85:383-8. 2003..In conclusion, it appears that T-type calcium channel expression vary in different patho-physiological conditions and that aldosterone, in several cell types, is able to modulate this expression...
Cytosolic calcium oscillations in signal transduction pathwaysMichel F Rossier
Division of Endocrinology Diabetology, Department of Internal Medicine, University Hospital, CH 1211 Geneva 14, Switzerland
Mini Rev Med Chem 2:353-60. 2002....
Control of calcium homeostasis by angiotensin II in adrenal glomerulosa cells through activation of p38 MAPKIrina Startchik
Division of Endocrinology and Diabetology, Department of Internal Medicine, and the Laboratory of Clinical Chemistry, Department of Pathology, University Hospital, CH-1211 Geneva 14, Switzerland
J Biol Chem 277:24265-73. 2002..The hormone exerts its action on the exchanger through a caffeine-sensitive pathway involving the p38 MAPK and lipoxygenase products...
Mineralocorticoid receptor antagonism prevents the electrical remodeling that precedes cellular hypertrophy after myocardial infarctionEmeline Perrier
INSERM U637 EA3759, IFR3, Montpellier, France
Circulation 110:776-83. 2004..We sought to establish the sequence of ionic events that link the initiating insult and MR to hypertrophy development...
Overexpression of an alpha 1H (Cav3.2) T-type calcium channel during neuroendocrine differentiation of human prostate cancer cellsPascal Mariot
Laboratoire de Physiologie Cellulaire, INSERM EPI9938, Batiment SN3, Universite des Sciences et Technologies de Lille, 59655 Villeneuve d Ascq cedex, France
J Biol Chem 277:10824-33. 2002..This voltage-dependent calcium channel could be involved in the stimulation of mitogenic factor secretion and could therefore be a target for future therapeutic strategies...
