Xavier Robin

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. pmc pROC: an open-source package for R and S+ to analyze and compare ROC curves
    Xavier Robin
    Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, Geneva, Switzerland
    BMC Bioinformatics 12:77. 2011
  2. pmc Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness
    Natalia Tiberti
    Translational Biomarker Group, Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland
    PLoS Negl Trop Dis 7:e2088. 2013
  3. doi The prognostic significance of the serum biomarker heart-fatty acidic binding protein in comparison with s100b in severe traumatic brain injury
    Bernhard Walder
    1 Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    J Neurotrauma 30:1631-7. 2013
  4. pmc Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness
    Natalia Tiberti
    Biomedical Proteomics Research Group, Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland
    PLoS ONE 7:e40909. 2012
  5. pmc Discovery and verification of osteopontin and Beta-2-microglobulin as promising markers for staging human African trypanosomiasis
    Natalia Tiberti
    Biomedical Proteomics Research Group, Medical University Centre, Geneva, Switzerland
    Mol Cell Proteomics 9:2783-95. 2010
  6. doi Matrix metalloproteinase-9 and intercellular adhesion molecule 1 are powerful staging markers for human African trypanosomiasis
    Alexandre Hainard
    Biomedical Proteomics Research Group, Medical University Centre, Geneva, Switzerland
    Trop Med Int Health 16:119-26. 2011
  7. pmc New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patients
    Natalia Tiberti
    Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland
    Clin Transl Med 2:1. 2013
  8. doi Bioinformatics for protein biomarker panel classification: what is needed to bring biomarker panels into in vitro diagnostics?
    Xavier Robin
    Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, Geneva, Switzerland
    Expert Rev Proteomics 6:675-89. 2009
  9. doi A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage
    Natacha Turck
    Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, DBSB CMU, rue Michel Servet, 1, 1211 Geneva 4, Switzerland
    Intensive Care Med 36:107-15. 2010
  10. ncbi EasyProt--an easy-to-use graphical platform for proteomics data analysis
    Florent Gluck
    Swiss Center for Applied Human Toxicology SCAHT, Geneva, Switzerland
    J Proteomics 79:146-60. 2013

Collaborators

Detail Information

Publications15

  1. pmc pROC: an open-source package for R and S+ to analyze and compare ROC curves
    Xavier Robin
    Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, Geneva, Switzerland
    BMC Bioinformatics 12:77. 2011
    ....
  2. pmc Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness
    Natalia Tiberti
    Translational Biomarker Group, Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland
    PLoS Negl Trop Dis 7:e2088. 2013
    ..New markers for treatment outcome evaluation are needed. We hypothesized that alternative CSF markers, able to diagnose the meningo-encephalitic stage of the disease, could also be useful for the evaluation of treatment outcome...
  3. doi The prognostic significance of the serum biomarker heart-fatty acidic binding protein in comparison with s100b in severe traumatic brain injury
    Bernhard Walder
    1 Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    J Neurotrauma 30:1631-7. 2013
    ..Early blood levels of H-FABP after sTBI have prognostic significance for survival and disability...
  4. pmc Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness
    Natalia Tiberti
    Biomedical Proteomics Research Group, Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland
    PLoS ONE 7:e40909. 2012
    ..In the present study we evaluated the potential of CXCL10, CXCL13, ICAM-1, VCAM-1, MMP-9, B2MG, neopterin and IgM to complement current methods for staging Trypanosoma brucei gambiense patients...
  5. pmc Discovery and verification of osteopontin and Beta-2-microglobulin as promising markers for staging human African trypanosomiasis
    Natalia Tiberti
    Biomedical Proteomics Research Group, Medical University Centre, Geneva, Switzerland
    Mol Cell Proteomics 9:2783-95. 2010
    ..8 and 5.5 respectively) make the two markers good candidates for the development of a test for staging HAT patients...
  6. doi Matrix metalloproteinase-9 and intercellular adhesion molecule 1 are powerful staging markers for human African trypanosomiasis
    Alexandre Hainard
    Biomedical Proteomics Research Group, Medical University Centre, Geneva, Switzerland
    Trop Med Int Health 16:119-26. 2011
    ....
  7. pmc New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patients
    Natalia Tiberti
    Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland
    Clin Transl Med 2:1. 2013
    ..b. rhodesiense patients. Further investigations are needed to better evaluate these molecules, alone or in panels, as alternatives to WBC to make reliable choice of treatment...
  8. doi Bioinformatics for protein biomarker panel classification: what is needed to bring biomarker panels into in vitro diagnostics?
    Xavier Robin
    Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, Geneva, Switzerland
    Expert Rev Proteomics 6:675-89. 2009
    ..In this article, we present a discussion of the bioinformatics aspects of biomarker panels and the concomitant challenges, including high dimensionality and low patient number and reproducibility...
  9. doi A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage
    Natacha Turck
    Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Medical University Centre, DBSB CMU, rue Michel Servet, 1, 1211 Geneva 4, Switzerland
    Intensive Care Med 36:107-15. 2010
    ....
  10. ncbi EasyProt--an easy-to-use graphical platform for proteomics data analysis
    Florent Gluck
    Swiss Center for Applied Human Toxicology SCAHT, Geneva, Switzerland
    J Proteomics 79:146-60. 2013
    ..To illustrate the EasyProt platform, we present two identification and quantification workflows based on isobaric tagging and label-free methods...
  11. pmc Matrix metalloproteinase 9 and cellular fibronectin plasma concentrations are predictors of the composite endpoint of length of stay and death in the intensive care unit after severe traumatic brain injury
    Jean Christophe Copin
    Geneva Neuroscience Center, University of Geneva, Geneva, Switzerland
    Scand J Trauma Resusc Emerg Med 20:83. 2012
    ..Secondary outcomes were the state of consciousness measured with the Glasgow Coma Scale (GCS) of survivors at 14 days and Glasgow Outcome Scale Extended (GOSE) at 3 months...
  12. pmc Blood glutathione S-transferase-π as a time indicator of stroke onset
    Natacha Turck
    Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland
    PLoS ONE 7:e43830. 2012
    ....
  13. pmc A combined CXCL10, CXCL8 and H-FABP panel for the staging of human African trypanosomiasis patients
    Alexandre Hainard
    Biomedical Proteomics Research Group, Medical University Centre, Geneva, Switzerland
    PLoS Negl Trop Dis 3:e459. 2009
    ..We hypothesized that markers of brain damage discovered by proteomic strategies and inflammation-related proteins could individually or in combination indicate the CNS invasion by the parasite...
  14. doi A suite of tools to analyse and publish 2-DE data
    Christine Hoogland
    Proteome Informatics Group, Swiss Institute of Bioinformatics, Geneva, Switzerland
    Proteomics 8:4907-9. 2008
    ..This short communication highlights in a single and summarised view, this workflow and the current bioinformatics solutions developed by the Proteome Informatics Group at the Swiss Institute of Bioinformatics...
  15. doi MIAPEGelDB, a web-based submission tool and public repository for MIAPE gel electrophoresis documents
    Xavier Robin
    Proteome Informatics Group, Swiss Institute of Bioinformatics, Geneva, Switzerland
    J Proteomics 71:249-51. 2008
    ..After publication by their author, documents in MIAPEGelDB can be viewed in HTML or plain text formats, and further used through stable URL links from remote resources. MIAPEGelDB is accessible at: http://miapegeldb.expasy.org/...