Research Topics
| Marc RighiniSummaryAffiliation: University Hospital Country: Switzerland Publications
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Detail Information
Publications
Clinical usefulness of D-dimer testing in cancer patients with suspected pulmonary embolismMarc Righini
Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
Thromb Haemost 95:715-9. 2006..Increasing the cut-off value of D-dimer in cancer patients might increase the test's clinical usefulness...
Management of severe ischemia of the hand following intra-arterial injectionMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland
Thromb Haemost 94:219-21. 2005
Clinical relevance of distal deep vein thrombosis. Review of literature dataMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, 24, Rue Micheli du Crest, 1211 Geneva 14, Switzerland
Thromb Haemost 95:56-64. 2006..There is an urgent need for randomised trials assessing the usefulness of anticoagulant treatment in distal DVT...
Complete venous ultrasound in outpatients with suspected pulmonary embolismM Righini
Division of Angiology and Haemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
J Thromb Haemost 7:406-12. 2009..Recent studies suggested a limited yield of proximal US when multislice computed tomography (MSCT) was used...
Extensive thromboembolic event as initial presentation of monoclonal gammopathy of undetermined significanceMarc Righini
Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
Thromb Haemost 96:93-4. 2006
Images in cardiovascular medicine. An unusual cause of hand cellulitisMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland
Circulation 115:e65-6. 2007
Venous thrombosis: risk factors and managementMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
Herz 32:27-34. 2007....
Clinical relevance of distal deep vein thrombosisMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
Curr Opin Pulm Med 14:408-13. 2008..To discuss pros and cons of anticoagulant treatment in the presence of symptomatic distal deep vein thrombosis...
[Post-catheterization false femoral aneurysms]M Righini
Division d angiologie et d hémostase HUG, Geneve
Rev Med Suisse 3:341-5. 2007..Compression echography is safe and effectiveness varies between 70 and 100%, according to studies. Thrombin injection seems particularly effective, is painless and has a limited rate of complications in expert hands...
Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolismM Righini
Division of Angiology and Haemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
J Thromb Haemost 5:1869-77. 2007....
Is it worth diagnosing and treating distal deep vein thrombosis? NoM Righini
Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
J Thromb Haemost 5:55-9. 2007..There is an urgent need for randomized trials assessing the usefulness of anticoagulant treatment in distal DVT...
[D-dimers measurement to predict the risk of thromboembolic recurrence]M Righini
Division d angiologie et d hémostase, Hopitaux Universitaires de Geneve, 24, Rue Micheli du Crest, 1211 Geneve, Suisse
Rev Med Interne 29:476-81. 2008..Moreover, standardization of the cut-off and of the time of blood sampling in relation to cessation of anticoagulation is warranted...
Pulmonary cement embolism after vertebroplastyMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, 24 rue Micheli-du-Crest, 1211 Geneva 14, Switzerland
Thromb Haemost 95:388-9. 2006
The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategiesMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
J Am Geriatr Soc 53:1039-45. 2005..Therefore, a rational diagnostic approach to PE in older people should rest mainly on the sequential use of those tests that have demonstrated strong diagnostic yield, accuracy, and safety in this population...
Diagnosis of pulmonary embolism by multidetector CT alone or combined with venous ultrasonography of the leg: a randomised non-inferiority trialMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
Lancet 371:1343-52. 2008..We compared this combination with a strategy in which both a negative venous ultrasonography of the leg and MSCT were needed to exclude pulmonary embolism...
[Treatment of postcatheterization femoral false aneurysms]M Righini
Division d angiologie et d hémostase, Hopitaux Universitaires de Geneve, Suisse
J Mal Vasc 29:63-72. 2004..As recurrences have been described with each of these techniques, every non-surgically-treated false aneurysm should be monitored for 24 hour with ultrasonography control to ensure effective thrombosis...
Effect of age on the performance of single detector helical computed tomography in suspected pulmonary embolismMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
Thromb Haemost 91:296-9. 2004..Our data suggest that age does not have a marked influence on the diagnostic performances of hCT in clinically suspected pulmonary embolism...
Clinical usefulness of D-dimer depending on clinical probability and cutoff value in outpatients with suspected pulmonary embolismMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospital, 24, Rue Micheli du Crest, 1211 Geneva 14, Switzerland
Arch Intern Med 164:2483-7. 2004....
[Diagnosis of suspected deep venous thrombosis and pulmonary embolism during pregnancy]M Righini
Service d angiologie et d hémostase, Hopital Universitaire de Geneve, 1211 Geneve 14
Rev Med Suisse 1:283, 286-9. 2005..Helical computed tomography (hCT) has widely replaced lung scan in the diagnostic approach of suspected pulmonary embolism. However, it has never been validated in pregnant women...
External validation and comparison of recently described prediction rules for suspected pulmonary embolismMarc Righini
Division of Angiology and Hemostasis, Geneva University Hospitals, Geneva, Switzerland
Curr Opin Pulm Med 10:345-9. 2004..Therefore, the purpose of this review is to discuss the external validation of these rules, because this particular point has been only recently achieved...
Diagnosis of venous thromboembolism: an updateHenri Bounameaux
Division of Angiology and Hemostasis, Department of Internal Medicine, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
Vasc Med 15:399-406. 2010..This review gives a critical appraisal of the sequential steps of the diagnostic work-up in suspected DVT or PE...
Usefulness of preemptive anticoagulation in patients with suspected pulmonary embolism: a decision analysisMarc Blondon
Division of General Internal Medicine, Department of Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland
Chest 142:697-703. 2012..The objective of this study was to compare the risks and benefits of bid low-molecular-weight heparin vs no treatment in patients with suspected PE...
Anti-(apolipoprotein A-1) IgGs are associated with high levels of oxidized low-density lipoprotein in acute coronary syndromeNicolas Vuilleumier
Division of Immunology and Allergy, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Clin Sci (Lond) 115:25-33. 2008..These results emphasize the role of humoral autoimmunity as a mediator of inflammation and coronary atherogenesis...
Influence of specific alternative diagnoses on the probability of pulmonary embolismAriane Testuz
Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
Thromb Haemost 95:958-62. 2006....
Venous thromboembolism: contemporary diagnostic and therapeutic aspectsH Bounameaux
Division of Angiology and Hemostasis, Department of Internal Medicine, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
Vasa 37:211-26. 2008..5-2) after an initial full-intensity treatment (INR 2-3) period of 3 to 12 months, and the emergence of new anticoagulant drugs such as direct oral synthetic inhibitors of thrombin or factor Xa...
Thromboprophylaxis with low-molecular-weight heparin after cesarean deliveryMarc Blondon
General Internal Medicine, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
Thromb Haemost 103:129-37. 2010..Our decision analysis suggests that the benefits of LMWH after cesarean delivery exceed the risks. This benefit is, however, very low in women with no risk factors...
[Diagnosis of venous thromboembolic disease during pregnancy]Helia Robert-Ebadi
Service d angiologie et d hémostase, HUG, 1211 Geneve 14
Rev Med Suisse 7:345-50. 2011..Fetal radiation is very low with both imaging techniques, and the potentially fatal outcome of undiagnosed PE widely justifies performing these tests...
Serial limited versus single complete compression ultrasonography for the diagnosis of lower extremity deep vein thrombosisRaphael Guanella
Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital, Rue Gabrielle Perret Gentil 4, Geneva 14, Switzerland
Semin Respir Crit Care Med 33:144-50. 2012..Incorporation of D-dimer testing and clinical pretest probability assessment in the diagnostic algorithm is beneficial because it allows excluding DVT without the need for diagnostic imaging in about a third of patients...
Portal vein thrombosis following a primary cytomegalovirus infection in an immunocompetent adultSalah Gueddi
Division of Angiology and Haemostasis, University Hospital of Geneva, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland
Thromb Haemost 95:199-201. 2006
Correlation between cardiac biomarkers and right ventricular enlargement on chest CT in non massive pulmonary embolismNicolas Vuilleumier
Department of Pathology, Clinical Chemistry, Geneva University Hospital, Switzerland
Thromb Res 121:617-24. 2008..Troponin I (cTnI), myoglobin, heart-type fatty acid binding protein (H-FABP), and natriuretic peptides (BNP, NTproBNP) were all reported to be elevated in patients with pulmonary embolism (PE)...
Differences in clinical presentation of pulmonary embolism in women and menH Robert-Ebadi
Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
J Thromb Haemost 8:693-8. 2010..The risk of recurrence of pulmonary embolism (PE) is higher in men than in women. Differences in clinical presentation of deep vein thrombosis (DVT) have been reported between the two genders but comparative data on PE are lacking...
[Is computed tomographic venography of lower limbs useful in suspected pulmonary embolism?]Gregoire Le Gal
Division d angiologie et d hémostase HUG, 1211 Geneve 14
Rev Med Suisse 4:354, 356-9. 2008..Recent studies have confirmed that CUS is no more mandatory when using the recent sensitive multi-slice computed tomography. These data limit the potential use of CT venography of the lower limbs veins in patients with suspected PE...
Diffuse fibromuscular dysplasia successfully treated with scoring balloon angioplasty in a 3-year-old boyRobert F Bonvini
Angiology Division, Heart Center Bad Krozingen, Südring 15, 79189 Bad Krozingen, Germany
Heart Vessels 24:460-2. 2009....
[Cardiac biomarkers and pulmonary embolism: prognostic stratification]Grégoire Blaudszun
Service de médecine interne générale, Departement de Medecine Interne, HUG, 1211 Geneve 14
Rev Med Suisse 5:2022-4, 2026-7. 2009..This article discusses more specifically the role of cardiac biomarkers (natriuretic peptides and troponin) in assessing PE prognosis and severity at the time of the diagnosis...
[New techniques for the endovascular treatment of peripheral arterial disease]R F Bonvini
Division de cardiologie interventionnelle, hôpitaux universitaires et faculté de médecine de Genève, 4 rue Gabrielle Gentil Perret, Geneva, Switzerland
J Mal Vasc 36:16-23. 2011..g. crossing, reentry, debulking devices) actually at the interventionist's disposal. As endovascular techniques are constantly evolving, a multidisciplinary approach, including all cardiovascular specialists, is often needed...
[Diagnostic strategy and comparison of clinical scores for pulmonary embolism]M Blondon
Service de médecine interne générale, Hopitaux Universitaires de Geneve, 4, rue Gabrielle Perret Gentil, 1211 Geneve 14, Suisse
Rev Med Interne 31:742-9. 2010..When positive, a multidetector thoracic CT will confirm or exclude the diagnosis. The utility of a lower-limb venous ultrasound is very low, and its use is therefore no longer recommended...
Incidence of atrial fibrillation after percutaneous closure of patent foramen ovale and small atrial septal defects in patients presenting with cryptogenic strokeR F Bonvini
Cardiology Service, University Hospital, Geneva, Switzerland
Int J Stroke 5:4-9. 2010..However, its precise incidence and mechanism are presently unclear and remain to be elucidated...
Impending paradoxical embolism. When and how to treat?R F Bonvini
Angiology and Hemostasis Division, University Hospital, Geneva, Switzerland
Ann Cardiol Angeiol (Paris) 57:234-7. 2008....
Cardiac biomarkers for risk stratification in non-massive pulmonary embolism: a multicenter prospective studyN Vuilleumier
Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals and University of Geneva, Geneva, Switzerland
J Thromb Haemost 7:391-8. 2009..Troponins (cTnI and cTnT), N-terminal pro-Brain Natriuretic Peptide (NT-proBNP), myoglobin, heart-type fatty acid-binding protein (H-FABP) and fibrin D-Dimer are emergent candidates for risk stratification in pulmonary embolism (PE)...
[Thrombopenias induced by heparin: diagnostic and therapeutic innovations]M Righini
Unite d hémostase, Departement de Medecine Interne, Hopital Universitaire de Geneve, Suisse
Rev Med Suisse Romande 121:313-8. 2001..In case of suspicion of HIT, treatment by heparin should imperatively be stopped and an alternative anticoagulant treatment should be started before any laboratory confirmation...
Contrast-enhanced sonographic diagnosis of unsuspected internal iliac vein thrombosisThomas de Perrot
Department of Radiology, Geneva University Hospitals, Geneva, Switzerland
J Clin Ultrasound 39:553-5. 2011..Contrast-enhanced ultrasound confirmed the diagnosis, by displaying a well-defined filling defect...
Use of anticoagulants in elderly patients: practical recommendationsHelia Robert-Ebadi
Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
Clin Interv Aging 4:165-77. 2009..Newer anticoagulants that are currently under study could simplify the management and increase the safety of anticoagulation in the future...
Skin necrosis is a clinical manifestation of low-molecular weight heparin-induced thrombocytopeniaPierre Fontana
Division of Angiology and Hemostasis, Geneva University Hospital, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland
Thromb Haemost 91:196-7. 2004
Treatment strategies for acute pulmonary embolismMarc Blondon
Division of General Internal Medicine, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
Expert Opin Pharmacother 10:1159-71. 2009..Acute pulmonary embolism (PE) is a life-threatening condition that has been treated with anticoagulation for almost 50 years...
[Diagnosis and treatment of thromboembolic events in pediatrics]M Righini
, , Suisse
J Mal Vasc 31:135-42. 2006....
[Value of D-dimers in diagnosis of acute pulmonary embolism]M Righini
, , 24, rue Micheli-du-Crest,
Presse Med 30:1945-52. 2001..The association of high clinical probability of pulmonary embolism and normal D-dimer leves is rare and has a weaker negative predictive value, even when the ELISA technique is used...
D-Dimer for venous thromboembolism diagnosis: 20 years laterM Righini
Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
J Thromb Haemost 6:1059-71. 2008....
[Clinical and ultrasonographic follow-up after femoro-popliteal venous bypass for lower limb revascularization]M Righini
Division d angiologie et d hémostase, Hopitaux Universitaires de Geneve, Suisse
J Mal Vasc 28:121-9. 2003..The results of an ongoing randomised controlled trial (the Vein Graft Trial) comparing duplex ultrasound surveillance against clinical surveillance only will certainly bring more data on the benefits of echographic surveillance...
Clinical prediction rules for pulmonary embolism: a systematic review and meta-analysisE Ceriani
Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
J Thromb Haemost 8:957-70. 2010..Pretest probability assessment is necessary to identify patients in whom pulmonary embolism (PE) can be safely ruled out by a negative D-dimer without further investigations...
Value of D-dimer testing for the exclusion of pulmonary embolism in patients with previous venous thromboembolismGregoire Le Gal
Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France
Arch Intern Med 166:176-80. 2006....
Pulmonary embolism in the elderly: a review on clinical, instrumental and laboratory presentationLuca Masotti
Internal Medicine, Cecina Hospital, Cecina, Italy
Vasc Health Risk Manag 4:629-36. 2008..The aim of the present study was to analyze the reported clinical presentation of PE in patients aged 65 and more...
A positive compression ultrasonography of the lower limb veins is highly predictive of pulmonary embolism on computed tomography in suspected patientsGregoire Le Gal
EA 3878, département de médecine interne et de pneumologie, CHU de la Cavale Blanche, 29609 Brest Cedex, France
Thromb Haemost 95:963-6. 2006..It allows ruling in the diagnosis of PE without further invasive and/or expensive testing in suspected patients...
Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based studyGregoire Le Gal
EA 3878 and Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France
Thromb Res 118:691-7. 2006....
D-dimer and venous thromboembolismGregoire Le Gal
Ann Intern Med 141:481-2; author reply 483. 2004
Prediction of pulmonary embolism in the emergency department: the revised Geneva scoreGregoire Le Gal
Brest University Hospital, Brest, France
Ann Intern Med 144:165-71. 2006..Diagnosis of pulmonary embolism requires clinical probability assessment. Implicit assessment is accurate but is not standardized, and current prediction rules have shortcomings...
Giant cell arteritis mimicking fever of unknown origin: potential diagnostic role of PET scanOlivier Chavaillaz
Service of Ambulatory Investigation, Department of Community Medicine, Geneva Switzerland
Thromb Haemost 95:390-2. 2006
Single complete compression ultrasonography for suspected deep venous thrombosis: ideal in routine clinical practice?Marc Righini
Ann Intern Med 141:888-9; author reply 889. 2004
Reproduction of chest pain by palpation: diagnostic accuracy in suspected pulmonary embolismGregoire Le Gal
Equipe d accueil 3878 GETBO, Brest University Hospital, 29609 Brest, France
BMJ 330:452-3. 2005
Pulmonary embolism in patients with unexplained exacerbations of chronic obstructive pulmonary diseaseGregoire Le Gal
Ann Intern Med 145:310; author reply 310. 2006
Bivalirudin in acute coronary syndromesRobert F Bonvini
N Engl J Med 356:1070; author reply 1070-1. 2007
Venous thrombosis in childrenMarc Righini
N Engl J Med 351:2451-2; author reply 2451-2. 2004
