A Richardson

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint Compensatory changes in GroEL/Gp31 affinity as a mechanism for allele-specific genetic interaction
    A Richardson
    Departement de Biochimie Medicale, University of Geneva, 1 rue Michel Servet, 1211 Geneva, Switzerland
    J Biol Chem 274:52-8. 1999
  2. pmc Genetic analysis of the bacteriophage T4-encoded cochaperonin Gp31
    A Richardson
    Universite de Geneve, Departement de Biochimie Medicale, Centre Medical Universitaire, CH 1211 Geneva 4, Switzerland
    Genetics 152:1449-57. 1999
  3. ncbi request reprint Pseudo-T-even bacteriophage RB49 encodes CocO, a cochaperonin for GroEL, which can substitute for Escherichia coli's GroES and bacteriophage T4's Gp31
    D Ang
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1 rue Michel Servet, CH 1211 Geneve 4, Switzerland
    J Biol Chem 276:8720-6. 2001
  4. ncbi request reprint Genetic analysis of bacteriophage-encoded cochaperonins
    D Ang
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1 rue Michel Servet, Geneve 4, CH 1211 Switzerland
    Annu Rev Genet 34:439-456. 2000
  5. ncbi request reprint The ins and outs of a molecular chaperone machine
    A Richardson
    Departement de Biochimie Medicale, Universite de Geneve, Switzerland
    Trends Biochem Sci 23:138-43. 1998
  6. ncbi request reprint The importance of a mobile loop in regulating chaperonin/ co-chaperonin interaction: humans versus Escherichia coli
    A Richardson
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva, Switzerland
    J Biol Chem 276:4981-7. 2001
  7. ncbi request reprint Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3
    S Masure
    Department of Biotechnology, Janssen Research Foundation, Beerse, Belgium
    Eur J Biochem 265:353-60. 1999

Detail Information

Publications7

  1. ncbi request reprint Compensatory changes in GroEL/Gp31 affinity as a mechanism for allele-specific genetic interaction
    A Richardson
    Departement de Biochimie Medicale, University of Geneva, 1 rue Michel Servet, 1211 Geneva, Switzerland
    J Biol Chem 274:52-8. 1999
    ..Mutations studied in this work indirectly alter affinity by modulating a folding transition in the Gp31 mobile loop or by modulating a hinged conformational change in GroEL...
  2. pmc Genetic analysis of the bacteriophage T4-encoded cochaperonin Gp31
    A Richardson
    Universite de Geneve, Departement de Biochimie Medicale, Centre Medical Universitaire, CH 1211 Geneva 4, Switzerland
    Genetics 152:1449-57. 1999
    ..Our genetic analyses highlight the crucial importance of all three highly conserved hydrophobic residues of the mobile loop of Gp31 in the productive interaction with GroEL...
  3. ncbi request reprint Pseudo-T-even bacteriophage RB49 encodes CocO, a cochaperonin for GroEL, which can substitute for Escherichia coli's GroES and bacteriophage T4's Gp31
    D Ang
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1 rue Michel Servet, CH 1211 Geneve 4, Switzerland
    J Biol Chem 276:8720-6. 2001
    ..Both the CocO wild type and epsilon22 proteins have been purified and shown in vitro to assist GroEL in the refolding of denatured citrate synthase...
  4. ncbi request reprint Genetic analysis of bacteriophage-encoded cochaperonins
    D Ang
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1 rue Michel Servet, Geneve 4, CH 1211 Switzerland
    Annu Rev Genet 34:439-456. 2000
    ..Conserved structural features between CocO and Gp31, which are absent from GroES, highlight their potential importance in specific cochaperonin function...
  5. ncbi request reprint The ins and outs of a molecular chaperone machine
    A Richardson
    Departement de Biochimie Medicale, Universite de Geneve, Switzerland
    Trends Biochem Sci 23:138-43. 1998
    ....
  6. ncbi request reprint The importance of a mobile loop in regulating chaperonin/ co-chaperonin interaction: humans versus Escherichia coli
    A Richardson
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva, Switzerland
    J Biol Chem 276:4981-7. 2001
    ..It seems likely that the single ring mitochondrial Hsp60 exhibits intrinsically lower affinity for the co-chaperonin that can be compensated for by a higher affinity mobile loop...
  7. ncbi request reprint Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3
    S Masure
    Department of Biotechnology, Janssen Research Foundation, Beerse, Belgium
    Eur J Biochem 265:353-60. 1999
    ..These observations suggest that Akt-3 is a promising target for the discovery of novel chemotherapeutic agents which do not interfere with insulin signalling...